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Key Largo

$374+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
Jun 23 — Jun 301
Mon 6/23
Mon 6/30
1 adult, Economy
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Cheap flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated June 18, 2025.

Round-trip from

$490
(American Airlines)

One-way from

$374
(American Airlines)

Popular in

May

Cheapest in

September
From Columbia Regional to Key Largo
Search Deals
One-way flight from Columbia Regional to Key Largo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
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Find flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 18, 2025.

This American Airlines deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/16:19 amCOU - MIA
1 stop7h 08mAmerican Airlines
Sat 7/55:18 amMIA - COU
1 stop6h 04mAmerican Airlines
Deal found 6/17$490
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:00 amCOU - MIA
1 stop11h 59mUnited Airlines
Mon 11/177:00 amMIA - COU
1 stop15h 10mUnited Airlines
Deal found 6/16$498

Cheapflights Fare Finder

Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Columbia

Fly to

Key Largo

Route

Depart

Return

Price

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Tue 7/1

6:19 am-2:27 pm

1 stop7h 08m

Miami

Sat 7/5

5:18 am-10:22 am

1 stop6h 04m

$490

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 11/8

9:00 am-9:59 pm

1 stop11h 59m

Miami

Mon 11/17

7:00 am-9:10 pm

1 stop15h 10m

$498

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Wed 7/16

6:17 am-12:35 pm

1 stop5h 18m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/17

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo

Rainfall in Key Largo by month

Plan your trip to Key Largo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

Temperature in Key Largo by month

Plan your trip to Key Largo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated June 18, 2025.
United Airlines
7.4
Good
8,809 reviews

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.0

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,809 reviews
United Airlines
7.4
Good
8,809 reviews

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.0

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,809 reviews

Overall

7.4

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.0

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 1 airline have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Columbia, Missouri to Key Largo (average of $229). Flying from Columbia, Missouri to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Columbia to Key Largo

Discover the top airline that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$390Average$646FlexibilityNo cancel feeOn-time71%

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