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Key Largo

$274+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
Mar 28 — Apr 41
Sat 3/28
Sat 4/4
1 adult, Economy
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Cheap flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 26, 2026.

This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:00 am
COU
-
MIA
1 stop7h 08m
United Airlines
Tue 4/289:00 am
MIA
-
COU
2 stops13h 03m
United Airlines
Deal found 2/25$274
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:00 am
COU
-
MIA
1 stop9h 29m
United Airlines
Fri 5/157:25 pm
MIA
-
COU
1 stop6h 08m
United Airlines
Deal found 2/25$314
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/72:41 pm
COU
-
MIA
1 stop6h 43m
United Airlines
Wed 3/1112:00 pm
MIA
-
COU
1 stop9h 20m
United Airlines
Deal found 2/24$343
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:23 pm
COU
-
MIA
1 stop6h 22m
United Airlines
Sat 4/258:55 am
MIA
-
COU
1 stop6h 53m
United Airlines
Deal found 2/25$348
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:05 am
COU
-
MIA
1 stop9h 43m
United Airlines
Tue 3/109:00 am
MIA
-
COU
2 stops12h 20m
United Airlines
Deal found 2/23$349
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:00 am
COU
-
MIA
2 stops11h 58m
United Airlines
Sat 4/259:00 am
MIA
-
COU
2 stops13h 03m
United Airlines
Deal found 2/25$359
This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:16 am
COU
-
MIA
1 stop11h 56m
American Airlines
Tue 4/2812:00 pm
MIA
-
COU
1 stop10h 30m
American Airlines
Deal found 2/25$362
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:02 am
COU
-
MIA
2 stops12h 26m
United Airlines
Fri 4/244:13 pm
MIA
-
COU
1 stop9h 20m
United Airlines
Deal found 2/23$365

Find flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated February 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$274
(United Airlines)

Popular in

December

Cheapest in

February

Average price

$268
Provider with most accurate pricing for Columbia Regional-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Miami flights.
Search Deals
From Columbia Regional to Key Largo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 4/25

5:00 am-1:08 pm

1 stop7h 08m

Miami

Tue 4/28

9:00 am-9:03 pm

2 stops13h 03m

$274

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Fri 5/8

9:00 am-7:29 pm

1 stop9h 29m

Miami

Fri 5/15

7:25 pm-12:33 am

1 stop6h 08m

$314

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Mon 4/20

3:23 pm-10:45 pm

1 stop6h 22m

Miami

Sat 4/25

9:00 am-9:03 pm

2 stops13h 03m

$354

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 6/6

3:05 pm-10:27 pm

1 stop6h 22m

Miami

Sat 6/13

4:06 pm-9:59 pm

1 stop6h 53m

$484

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Wed 7/29

5:00 am-3:04 pm

1 stop9h 04m

Miami

Mon 8/3

5:22 pm-2:30 pm

2 stops22h 08m

$515

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 4/25

5:00 am-1:08 pm

1 stop7h 08m

Miami

Wed 4/29

12:24 pm-9:56 pm

1 stop10h 32m

$544

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 3/7

2:41 pm-10:24 pm

1 stop6h 43m

$405

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Wed 3/4

6:00 am-12:55 pm

1 stop5h 55m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/24

Sorted by cheapest first

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo

How much does it cost to fly round-trip from Columbia, Missouri to Key Largo?

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated February 26, 2026.
See what other customers who have flown with American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,353 reviews

Crew

8.0

Entertainment

6.9

Food

6.4

Boarding

7.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,353 reviews
American Airlines
7.2
Good
11,353 reviews

Crew

8.0

Entertainment

6.9

Food

6.4

Boarding

7.5

Overall

7.2

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 1 airline have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Columbia, Missouri to Key Largo?

    There are many flights that can get you from Columbia, Missouri to Key Largo in 7h 08m. Fly via United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Columbia to Key Largo

Discover the top airline that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$420Average$607FlexibilityNo cancel feeOn-time71%

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