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Key Largo

$357+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
out 11 — out 181
sáb 10/11
sáb 10/18
1 adult, Economy
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Cheap flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated setembro 11, 2025.

Round-trip from

$357
(American Airlines)

Popular in

May

Cheapest in

September

Average price

$477
From Columbia Regional to Key Largo
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on setembro 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/307:24 pmCOU - MIA
1 stop12h 51mAmerican Airlines
qui 1/11:40 pmMIA - COU
1 stop9h 18mAmerican Airlines
Deal found 9/11$409
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 10/247:49 pmCOU - MIA
1 stop12h 16mAmerican Airlines
sáb 11/16:35 amMIA - COU
1 stop13h 44mAmerican Airlines
Deal found 9/9$430
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/1011:54 amCOU - MIA
1 stop10h 31mAmerican Airlines
sáb 12/136:20 amMIA - COU
1 stop13h 44mAmerican Airlines
Deal found 9/10$441
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 10/242:52 pmCOU - MIA
2 stops22h 50mUnited Airlines
sáb 11/16:45 amMIA - COU
1 stop15h 34mUnited Airlines
Deal found 9/9$499
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 12/109:00 amCOU - MIA
1 stop11h 59mUnited Airlines
sáb 12/139:00 amMIA - COU
2 stops13h 22mUnited Airlines
Deal found 9/10$522
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
qua 9/244:23 pmCOU - MIA
1 stop5h 42mAmerican Airlines
dom 9/286:20 amMIA - COU
1 stop7h 46mAmerican Airlines
Deal found 9/9$570
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 12/303:10 pmCOU - MIA
1 stop18h 20mUnited Airlines
qui 1/16:20 amMIA - COU
2 stops15h 59mUnited Airlines
Deal found 9/11$628

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 11, 2025.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Columbia

Fly to

Key Largo

Route

Depart

Return

Price

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

dom 2/22

6:03 am-9:59 pm

1 stop14h 56m

Miami

sáb 2/28

9:12 am-8:00 pm

1 stop11h 48m

$357

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

ter 12/30

7:24 pm-9:15 am

1 stop12h 51m

Miami

qui 1/1

1:40 pm-9:58 pm

1 stop9h 18m

$409

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

sex 1/23

3:10 pm-3:05 pm

1 stop22h 55m

Miami

qua 1/28

12:18 pm-9:37 pm

1 stop10h 19m

$441

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

qua 12/10

11:54 am-11:25 pm

1 stop10h 31m

Miami

sáb 12/13

6:20 am-7:04 pm

1 stop13h 44m

$441

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

qui 1/22

8:09 am-10:15 pm

1 stop13h 06m

Miami

qua 1/28

12:18 pm-9:37 pm

1 stop10h 19m

$457

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

qui 1/1

8:05 am-10:15 pm

1 stop13h 10m

Miami

qua 1/14

12:18 pm-9:37 pm

1 stop10h 19m

$457

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

sex 10/24

2:52 pm-2:42 pm

2 stops22h 50m

Miami

sáb 11/1

6:45 am-9:19 pm

1 stop15h 34m

$499

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

dom 2/22

3:16 pm-8:21 pm

2 stops28h 05m

Miami

sáb 2/28

7:35 pm-2:29 pm

1 stop19h 54m

$505

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

dom 12/7

6:15 pm-9:43 pm

2 stops26h 28m

$728

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

dom 12/7

12:08 pm-8:56 pm

1 stop7h 48m

$766

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated setembro 11, 2025.
See what other customers who have flown with American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Food

6.4

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 1 airline have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Columbia, Missouri to Key Largo?

    There are many flights that can get you from Columbia, Missouri to Key Largo in 14h 56m. Fly via American Airlines or United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Key Largo?

    Currently, September is the cheapest month in which you can book a flight from Columbia, Missouri to Key Largo (average of $232). Flying from Columbia, Missouri to Key Largo in March is currently the most expensive (average of $289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Columbia to Key Largo

Discover the top airline that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated setembro 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$390Average$592FlexibilityNo cancel feeOn-time71%

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