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Key Largo

$266+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
Aug 2 — Aug 91
Sun 8/2
Sun 8/9
1 adult, Economy
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Cheap flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.

This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:00 am
COU
-
MIA
1 stop5h 57m
United Airlines
Sat 8/15:32 pm
MIA
-
COU
1 stop7h 01m
United Airlines
Deal found 6/30$330
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:15 am
COU
-
MIA
1 stop7h 39m
United Airlines
Sat 9/53:57 pm
MIA
-
COU
1 stop7h 58m
United Airlines
Deal found 6/30$333
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3011:15 am
COU
-
MIA
2 stops11h 29m
United Airlines
Wed 10/71:26 pm
MIA
-
COU
2 stops10h 29m
United Airlines
Deal found 7/1$343
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:25 pm
COU
-
MIA
1 stop6h 02m
United Airlines
Mon 8/35:32 pm
MIA
-
COU
1 stop7h 01m
United Airlines
Deal found 6/30$355
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:25 pm
COU
-
MIA
1 stop6h 02m
United Airlines
Mon 7/274:10 pm
MIA
-
COU
1 stop8h 23m
United Airlines
Deal found 7/2$356
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:00 am
COU
-
MIA
1 stop5h 57m
United Airlines
Sun 7/195:40 pm
MIA
-
COU
1 stop6h 53m
United Airlines
Deal found 7/1$394
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:19 am
COU
-
MIA
2 stops11h 25m
United Airlines
Sat 10/31:26 pm
MIA
-
COU
2 stops10h 29m
United Airlines
Deal found 7/1$395
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
COU
-
MIA
1 stop7h 39m
United Airlines
Wed 9/23:57 pm
MIA
-
COU
1 stop7h 58m
United Airlines
Deal found 7/2$398
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:44 am
COU
-
MIA
1 stop14h 09m
American Airlines
Sat 10/38:22 am
MIA
-
COU
1 stop13h 50m
American Airlines
Deal found 7/1$408

Find flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated July 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$330
(United Airlines)

One-way from

$266
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$398
Provider with most accurate pricing for Columbia Regional-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Miami flights.
Search Deals
From Columbia Regional to Key Largo
Search Deals
One-way flight from Columbia Regional to Key Largo
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 9/26

11:19 am-11:44 pm

2 stops11h 25m

Miami

Sat 10/3

1:26 pm-10:55 pm

2 stops10h 29m

$395

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 8/29

6:15 am-2:54 pm

1 stop7h 39m

Miami

Wed 9/2

3:57 pm-10:55 pm

1 stop7h 58m

$398

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Wed 9/30

6:15 am-6:52 pm

3 stops11h 37m

Miami

Wed 10/7

1:26 pm-10:55 pm

2 stops10h 29m

$414

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Thu 8/13

6:15 am-2:54 pm

1 stop7h 39m

Miami

Tue 8/18

11:30 am-8:59 pm

2 stops10h 29m

$479

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Tue 7/14

8:00 am-2:57 pm

1 stop5h 57m

Miami

Sat 7/18

5:32 pm-11:33 pm

1 stop7h 01m

$489

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Thu 9/3

6:15 am-2:54 pm

1 stop7h 39m

Miami

Sun 9/6

4:13 pm-10:55 pm

1 stop7h 42m

$499

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 8/29

9:00 am-10:34 pm

2 stops12h 34m

Miami

Mon 8/31

11:30 am-10:16 am

2 stops23h 46m

$555
Quickest round-trip

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Tue 7/21

8:00 am-2:57 pm

1 stop5h 57m

Miami

Sun 7/26

5:40 pm-11:33 pm

1 stop6h 53m

$567
Cheapest one-way

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Mon 7/27

10:06 am-12:31 am

3 stops37h 25m

$266
Quickest one-way

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Mon 7/27

8:00 am-2:57 pm

1 stop5h 57m

$298

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated July 3, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,927 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,927 reviews
United Airlines
7.4
Good
9,927 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.1
Good
11,764 reviews
United Airlines
7.4
Good
9,927 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Overall

7.4

Food

6.7

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 2 airlines have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Columbia, Missouri to Key Largo?

    There are many flights that can get you from Columbia, Missouri to Key Largo in 5h 57m. Fly via United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Columbia to Key Largo

Discover the top 2 airlines that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$268Average$420FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$333Average$552FlexibilityNo cancel feeOn-time71%

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