HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Jacksonville

$625+ Cheap flights from Des Moines to Jacksonville, NC (DSM - OAJ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — OAJ
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Jacksonville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Jacksonville

Cheapest flights from Des Moines to Jacksonville
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:52 pmDSM - OAJ
2 stops14h 31mAmerican Airlines
Fri 1/27:55 pmOAJ - DSM
1 stop5h 42mAmerican Airlines
Deal found 12/12$625
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:41 amDSM - OAJ
1 stop4h 46mAmerican Airlines
Thu 12/187:55 pmOAJ - DSM
1 stop5h 42mAmerican Airlines
Deal found 12/14$1,050

Find flight deals from Des Moines to Jacksonville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (OAJ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$514
(Delta)
Provider with most accurate pricing for Des Moines-Jacksonville Albert J Ellis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Jacksonville Albert J Ellis flights.
Search Deals
From Des Moines to Jacksonville Albert J Ellis
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Des Moines

Fly to

Jacksonville

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - OAJ

DSMOAJ

Des Moines

Sun 12/28

6:52 pm-10:23 am

2 stops14h 31m

Jacksonville Albert J Ellis

Fri 1/2

7:55 pm-12:37 am

1 stop5h 42m

$625

Des MoinesJacksonville

DSM - OAJ

DSMOAJ

Des Moines

Thu 12/18

6:41 am-12:27 pm

1 stop4h 46m

Jacksonville Albert J Ellis

Thu 12/18

7:55 pm-12:37 am

1 stop5h 42m

$1,050

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/12

Compare providers for flights from Des Moines to Jacksonville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Jacksonville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Jacksonville, North Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Jacksonville, North Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Jacksonville, North Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Jacksonville, North Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Jacksonville, North Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Jacksonville

What is the cheapest month to book a flight from Des Moines to Jacksonville, North Carolina?

Currently, July is the cheapest month in which you can book a flight from Des Moines to Jacksonville, North Carolina (average of $247). Flying from Des Moines to Jacksonville, North Carolina in October is currently the most expensive (average of $622). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Jacksonville, North Carolina?

    American Airlines can get you from Des Moines to Jacksonville, North Carolina in just under 14h 31m. Your travel time can differ by up to . Des Moines and Jacksonville, North Carolina are separated by a distance of 984 mi.

  • Can I find deals for flights from Des Moines to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Jacksonville.

  • Can I find deals for business class flights from Des Moines to Jacksonville?

    Yes. Cheapflights offers flight deals from Des Moines to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Jacksonville, North Carolina?

    Currently, July is the cheapest month in which you can book a flight from Des Moines to Jacksonville, North Carolina (average of $247). Flying from Des Moines to Jacksonville, North Carolina in October is currently the most expensive (average of $622). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Jacksonville

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Charlotte flights
Omaha to Charlotte flights
Cedar Rapids to Charlotte flights
Moline to Charlotte flights
Des Moines to Knoxville flights
Des Moines to Raleigh flights
Omaha to Norfolk flights
Cedar Rapids to Raleigh flights
Moline to Myrtle Beach flights
Des Moines to Greensboro flights
Cedar Rapids to Knoxville flights
Cedar Rapids to Myrtle Beach flights
Omaha to Raleigh flights
Des Moines to Norfolk flights
Moline to Raleigh flights
Omaha to Asheville flights
Des Moines to Wilmington flights
Omaha to Myrtle Beach flights
Cedar Rapids to Wilmington flights
Cedar Rapids to Norfolk flights
Cedar Rapids to Blountville flights
Des Moines to Asheville flights
Omaha to Greensboro flights
Omaha to Wilmington flights
Des Moines to Myrtle Beach flights
Moline to Wilmington flights
Cedar Rapids to Asheville flights
Moline to Knoxville flights
Omaha to Fayetteville flights
Cedar Rapids to Jacksonville flights
Moline to Fayetteville flights
Omaha to Knoxville flights
Cedar Rapids to Greensboro flights
Moline to Norfolk flights
Sioux City to Charlotte flights
La Crosse to Charlotte flights
Moline to Asheville flights
Moline to Greensboro flights
Des Moines to Blountville flights
Sioux City to Greensboro flights
Omaha to Jacksonville flights
Sioux City to Raleigh flights
Sioux City to Knoxville flights
Dubuque to Charlotte flights
Waterloo to Raleigh flights
Omaha to Greenville flights
Omaha to Blountville flights
Sioux City to Fayetteville flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.