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$538+ Cheap flights from Des Moines to Jacksonville, NC (DSM - OAJ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — OAJ
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Jacksonville

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Jacksonville (OAJ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$538
(Delta)
From Des Moines to Jacksonville Albert J Ellis
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Cheapest flights from Des Moines to Jacksonville
Explore the most affordable flight options available from Des Moines to Jacksonville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/25:44 amDSM - OAJ
1 stop4h 24mDelta
mié. 10/84:30 pmOAJ - DSM
1 stop7h 00mDelta
Deal found 9/11$538

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Des Moines to Jacksonville that are best for you.

Fly from

Des Moines

Fly to

Jacksonville

Route

Depart

Return

Price

Des MoinesJacksonville

DSM - OAJ

DSMOAJ

Des Moines

jue. 10/2

5:44 am-11:08 am

1 stop4h 24m

Jacksonville Albert J Ellis

mié. 10/8

4:30 pm-10:30 pm

1 stop7h 00m

$538

Des MoinesJacksonville

DSM - OAJ

DSMOAJ

Des Moines

dom. 10/26

5:05 am-2:23 pm

2 stops8h 18m

$603

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Des Moines to Jacksonville

Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Jacksonville

Get insights into the airlines that provide service to Jacksonville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Jacksonville. Reviews last updated septiembre 11, 2025.
See what other customers who have flown with American Airlines from Des Moines to Jacksonville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.4

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Jacksonville, North Carolina?

    Delta can get you from Des Moines to Jacksonville, North Carolina in just under 4h 24m. Your travel time can differ by up to . Des Moines and Jacksonville, North Carolina are separated by a distance of 984 mi.

  • What is the cheapest airline to fly from Des Moines to Jacksonville, North Carolina round-trip?

    American Airlines, at $376, was found to be the cheapest airline from Des Moines to Jacksonville, North Carolina..

  • Can I find deals for flights from Des Moines to Jacksonville that include hotel bookings?

    Yes. In addition to deals on Des Moines to Jacksonville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Jacksonville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Jacksonville.

  • Can I find deals for business class flights from Des Moines to Jacksonville?

    Yes. Cheapflights offers flight deals from Des Moines to Jacksonville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Jacksonville, North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Jacksonville, North Carolina (average of $366). Flying from Des Moines to Jacksonville, North Carolina in December is currently the most expensive (average of $490). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top airline flying from Des Moines to Jacksonville

Discover the top airline that operate flights from Des Moines to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$376Average$504FlexibilityNo cancel feeOn-time71%

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