$384+ Cheap flights from Missouri to Jacksonville, NC (OAJ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — OAJ
Jan 26 — Feb 21
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Jacksonville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Jacksonville
Best flights from Missouri to JacksonvilleDiscover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.
Discover carefully curated flight deals from Missouri to Jacksonville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 amSTL - OAJ
1 stop6h 34mDelta
Sun 3/12:15 pmOAJ - STL
1 stop4h 36mDelta
Deal found 12/25![Delta logo]()
$384
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:04 amSTL - OAJ
2 stops8h 23mAmerican Airlines
Sun 3/15:00 amOAJ - STL
1 stop4h 32mAmerican Airlines
Deal found 12/25![American Airlines logo]()
$389
Find flight deals from Missouri to Jacksonville
Keep the following information in mind while searching for Missouri to Jacksonville flight deals. Data was last updated December 27, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $384 (Delta) |
Popular in | December |
Cheapest in | August |
Average price | $727 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Jacksonville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Missouri to Jacksonville that are best for you.
Fly from
Missouri
Fly to
Jacksonville
Route
Depart
Return
Price
St. LouisJacksonville
STL - OAJ
STLOAJ
Lambert-St Louis
Thu 2/26
6:00 am-1:34 pm
1 stop6h 34m
Jacksonville Albert J Ellis
Sun 3/1
2:15 pm-5:51 pm
1 stop4h 36m
$384
St. LouisJacksonville
STL - OAJ
STLOAJ
Lambert-St Louis
Thu 2/26
10:04 am-7:27 pm
2 stops8h 23m
Jacksonville Albert J Ellis
Sun 3/1
5:00 am-8:32 am
1 stop4h 32m
$389
Best time to book a flight from Missouri to Jacksonville
Have a flexible travel schedule? Discover the best time to fly to Jacksonville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Jacksonville
What is the cheapest month to book a flight from Missouri to Jacksonville, North Carolina?
Currently, June is the cheapest month in which you can book a flight from Missouri to Jacksonville, North Carolina (average of $162). Flying from Missouri to Jacksonville, North Carolina in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Jacksonville, North Carolina?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Jacksonville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes for Missouri to Jacksonville
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Missouri to Jacksonville
Discover the top 2 airlines that operate flights from Missouri to Jacksonville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$222 | Average$394 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$266 | Average$425 | FlexibilityNo cancel fee | On-timeN/A |