HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Irvine

$117+ Cheap flights from Myrtle Beach (MYR) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — LAX
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Myrtle Beach to Irvine with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Myrtle Beach Intl to Irvine are usually found in September or August, booked 85 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from Myrtle Beach to Irvine

Keep the following information in mind while searching for Myrtle Beach to Irvine flight deals. Data was last updated November 3, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$248
(CheapOair)

One-way from

$117
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$426
Provider with most accurate pricing for Myrtle Beach Intl-Los Angeles flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Los Angeles flights.
Search Deals
From Myrtle Beach Intl to Irvine
Search Deals
One-way flight from Myrtle Beach Intl to Irvine
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Myrtle Beach to Irvine

Cheapest flights from Myrtle Beach to Irvine
Explore the most affordable flight options available from Myrtle Beach to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/252:46 pmMYR - LAX
2 stops19h 08mSpirit Airlines
Tue 12/210:40 pmLAX - MYR
2 stops18h 14mSpirit Airlines
Deal found 11/3$268
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:59 pmMYR - LAX
1 stop19h 30mMultiple Airlines
Tue 12/161:42 pmLAX - MYR
2 stops25h 06mMultiple Airlines
Deal found 11/2$271
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:59 pmMYR - LAX
2 stops20h 48mMultiple Airlines
Thu 12/1112:03 pmLAX - MYR
1 stop26h 45mMultiple Airlines
Deal found 11/3$281
This Trip.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:46 pmMYR - LAX
2 stops12h 04mSpirit Airlines
Mon 11/248:57 amLAX - MYR
1 stop11h 57mSpirit Airlines
Deal found 11/2$282
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:46 pmMYR - LAX
1 stop8h 53mSpirit Airlines
Mon 11/248:57 amLAX - MYR
1 stop11h 57mSpirit Airlines
Deal found 11/2$284
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:54 amMYR - LAX
1 stop12h 25mSpirit Airlines
Wed 1/75:59 pmLAX - MYR
2 stops13h 42mSpirit Airlines
Deal found 11/3$293
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:46 pmMYR - LAX
1 stop8h 53mSpirit Airlines
Fri 11/288:57 amLAX - MYR
1 stop11h 57mSpirit Airlines
Deal found 11/2$294
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:41 pmMYR - LAX
2 stops22h 30mSpirit Airlines
Thu 12/1111:30 pmLAX - MYR
2 stops15h 18mSpirit Airlines
Deal found 11/3$297
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:13 amMYR - LAX
1 stop16h 30mSpirit Airlines
Mon 11/2410:40 pmLAX - MYR
2 stops22h 14mSpirit Airlines
Deal found 11/2$310

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Irvine that are best for you.

Fly from

Myrtle Beach

Fly to

Irvine

Route

Depart

Return

Price

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 1/28

9:59 am-8:11 pm

1 stop13h 12m

Los Angeles

Wed 2/4

5:18 pm-10:41 am

2 stops14h 23m

$248

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 11/21

2:46 pm-9:30 pm

2 stops33h 44m

Los Angeles

Sun 12/7

12:03 pm-5:48 pm

1 stop26h 45m

$284

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Thu 4/30

4:01 pm-10:59 pm

1 stop9h 58m

Los Angeles

Sun 5/10

11:59 pm-11:38 am

1 stop8h 39m

$291

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Thu 11/20

2:46 pm-11:50 pm

2 stops12h 04m

Los Angeles

Mon 11/24

10:40 pm-11:54 pm

2 stops22h 14m

$299

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Tue 11/25

2:46 pm-6:54 am

2 stops19h 08m

Los Angeles

Tue 12/2

5:35 am-7:54 pm

1 stop11h 19m

$304

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Thu 1/1

3:59 pm-10:38 pm

1 stop9h 39m

Los Angeles

Wed 1/7

1:28 pm-10:05 am

1 stop17h 37m

$309

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 12/29

9:54 am-7:19 pm

1 stop12h 25m

Los Angeles

Wed 1/7

8:59 pm-2:58 pm

1 stop14h 59m

$310

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 11/21

2:46 pm-8:39 pm

1 stop8h 53m

$117

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Tue 12/2

2:46 pm-6:47 am

2 stops19h 01m

$127

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 12/15

9:54 am-9:11 pm

2 stops38h 17m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 14 results
1
2

Best time to book a flight from Myrtle Beach to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Irvine

How far ahead should I book a flight from Myrtle Beach to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Irvine. Price data was last updated on October 31, 2025.

The price you pay for your flight from Myrtle Beach to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Myrtle Beach to Irvine?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $91). Flying from Myrtle Beach to Irvine in January is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IR9?

Find hourly flight availability from Myrtle Beach to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Irvine is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated November 3, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Myrtle Beach to Irvine to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,001 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,036 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,114 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Overall

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Irvine?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Irvine. 4 airlines have flights from Myrtle Beach Intl to Irvine on a regular basis. Booking flights from Myrtle Beach Intl to Irvine should not be difficult; the airport handles an average of 0 outbound flights to Irvine per day.

  • How long is the flight from Myrtle Beach to Irvine?

    Airlines like Spirit Airlines fly from Myrtle Beach to Irvine in about 23h 31m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 2251 mi.

  • Can I find deals for flights from Myrtle Beach to Irvine that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Irvine.

  • Can I find deals for business class flights from Myrtle Beach to Irvine?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Irvine?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $91). Flying from Myrtle Beach to Irvine in January is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Myrtle Beach to Irvine

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Las Vegas flights
Charlotte to Los Angeles flights
Charleston to Las Vegas flights
Charlotte to San Francisco flights
Charlotte to Ontario flights
Charlotte to San Diego flights
Greenville to Las Vegas flights
Savannah to Las Vegas flights
Charlotte to Santa Ana flights
Charleston to Los Angeles flights
Myrtle Beach to Las Vegas flights
Columbia to Las Vegas flights
Charleston to San Francisco flights
Charlotte to Sacramento flights
Charlotte to San Jose flights
Greenville to San Francisco flights
Charlotte to Palm Springs flights
Savannah to Los Angeles flights
Charleston to Sacramento flights
Charleston to Ontario flights
Greenville to Palm Springs flights
Savannah to San Francisco flights
Augusta to Las Vegas flights
Charlotte to Fresno flights
Greenville to Ontario flights
Greenville to Santa Ana flights
Columbia to Los Angeles flights
Greenville to Los Angeles flights
Augusta to Los Angeles flights
Charleston to Palm Springs flights
Charlotte to Reno flights
Savannah to Ontario flights
Columbia to San Diego flights
Charleston to San Diego flights
Charlotte to Burbank flights
Myrtle Beach to San Diego flights
Myrtle Beach to Los Angeles flights
Greenville to Oakland flights
Savannah to San Diego flights
Greenville to San Diego flights
Charlotte to Oakland flights
Columbia to Ontario flights
Greenville to Sacramento flights
Charlotte to Monterey flights
Charlotte to Santa Barbara flights
Savannah to Palm Springs flights
Charleston to Santa Ana flights
Greenville to San Jose flights
Charleston to Reno flights
Charleston to Long Beach flights

Top 4 airlines flying from Myrtle Beach to Irvine

Discover the top 4 airlines that operate flights from Myrtle Beach to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$207Average$368FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$312Average$477FlexibilityNo cancel feeOn-time71%
DeltaCheapest$312Average$491FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$409Average$527FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.