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$112+ Cheap flights from Myrtle Beach (MYR) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — LAX
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to Irvine are usually found in September or August, booked 36 days in advance, depart on a Saturday or Tuesday and return on a Tuesday

Cheap flight deals from Myrtle Beach to Irvine

Cheapest flights from Myrtle Beach to Irvine
Explore the most affordable flight options available from Myrtle Beach to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:18 pmMYR - LAX
1 stop8h 22mDelta
Sat 12/2712:15 pmLAX - MYR
1 stop7h 35mDelta
Deal found 12/16$597
This CheapOair deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:54 amMYR - LAX
1 stop12h 25mSpirit Airlines
Sat 12/278:23 amLAX - MYR
1 stop12h 36mSpirit Airlines
Deal found 12/17$658
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:54 amMYR - LAX
1 stop12h 25mSpirit Airlines
Tue 12/239:20 pmLAX - MYR
2 stops41h 48mSpirit Airlines
Deal found 12/17$673
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:54 amMYR - LAX
2 stops24h 24mSpirit Airlines
Thu 1/18:23 amLAX - MYR
1 stop12h 36mSpirit Airlines
Deal found 12/16$693
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/283:59 pmMYR - LAX
1 stop9h 39mMultiple Airlines
Sun 1/49:20 pmLAX - MYR
2 stops41h 48mMultiple Airlines
Deal found 12/16$719
This CheapOair deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - LAX
1 stop12h 25mSpirit Airlines
Sat 1/36:00 amLAX - MYR
2 stops14h 59mSpirit Airlines
Deal found 12/16$740
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:54 amMYR - LAX
1 stop12h 25mSpirit Airlines
Sun 1/49:20 pmLAX - MYR
2 stops41h 48mSpirit Airlines
Deal found 12/16$746
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:25 pmMYR - LAX
1 stop8h 05mSouthwest
Sun 1/411:40 pmLAX - MYR
1 stop9h 25mSouthwest
Deal found 12/16$767

Find flight deals from Myrtle Beach to Irvine

Keep the following information in mind while searching for Myrtle Beach to Irvine flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$218
(Kiwi.com)

One-way from

$112
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$522
Provider with most accurate pricing for Myrtle Beach Intl-Los Angeles flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Los Angeles flights.
Search Deals
From Myrtle Beach Intl to Irvine
Search Deals
One-way flight from Myrtle Beach Intl to Irvine
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Irvine that are best for you.

Fly from

Myrtle Beach

Fly to

Irvine

Route

Depart

Return

Price

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 1/21

10:00 am-12:33 pm

1 stop29h 33m

Los Angeles

Mon 1/26

8:20 am-2:42 pm

1 stop27h 22m

$218

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Thu 5/28

3:53 pm-10:44 pm

1 stop9h 51m

Los Angeles

Wed 6/3

11:59 pm-10:05 am

1 stop7h 06m

$246

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 2/9

8:15 pm-6:02 pm

2 stops24h 47m

Los Angeles

Wed 2/18

9:12 am-8:13 am

3 stops20h 01m

$259

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Sat 2/28

9:09 am-11:50 pm

1 stop17h 41m

Los Angeles

Sat 3/7

11:34 pm-10:05 am

1 stop6h 31m

$273

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Sat 1/10

1:07 pm-10:40 pm

2 stops12h 33m

Los Angeles

Fri 1/16

12:33 am-7:20 pm

2 stops15h 47m

$296

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 1/9

8:15 pm-5:48 pm

2 stops24h 33m

Los Angeles

Sun 1/11

11:59 pm-7:20 pm

1 stop16h 21m

$302

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 1/9

10:00 am-12:33 pm

1 stop29h 33m

Los Angeles

Sun 1/11

11:59 pm-7:20 pm

1 stop16h 21m

$322

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 2/9

1:20 pm-7:20 pm

1 stop9h 00m

Los Angeles

Wed 2/18

6:00 am-7:45 pm

2 stops10h 45m

$355

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 2/25

10:02 am-12:38 pm

1 stop29h 36m

$112

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 1/9

8:15 pm-10:40 pm

2 stops29h 25m

$147

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 15 results
1
2

Best time to book a flight from Myrtle Beach to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Irvine

How far ahead should I book a flight from Myrtle Beach to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Irvine. Price data was last updated on December 12, 2025.

The price you pay for your flight from Myrtle Beach to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 34 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Myrtle Beach to Irvine?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $91). Flying from Myrtle Beach to Irvine in December is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IR9?

Find hourly flight availability from Myrtle Beach to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Myrtle Beach to Irvine is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

How much does it cost to fly round-trip from Myrtle Beach to Irvine?

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Myrtle Beach to Irvine to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Food

7.0

Overall

7.9

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Overall

7.9

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,005 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Overall

7.9

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,055 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Overall

7.9

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,190 reviews
Southwest
7.9
Good
4,250 reviews

Food

7.0

Overall

7.9

Comfort

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Irvine?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Irvine. 4 airlines have flights from Myrtle Beach Intl to Irvine on a regular basis. Booking flights from Myrtle Beach Intl to Irvine should not be difficult; the airport handles an average of 0 outbound flights to Irvine per day.

  • How long is the flight from Myrtle Beach to Irvine?

    Airlines like Spirit Airlines and Breeze Airways fly from Myrtle Beach to Irvine in about 9h 51m. The time it takes to get you to your destination can typically vary by up to 19h 42m. Airlines will cover a distance of 2251 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Irvine one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $93. Users have also found prices from $132 and $156 on American Airlines and Southwest, respectively.

  • Can I find deals for flights from Myrtle Beach to Irvine that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Irvine.

  • Can I find deals for business class flights from Myrtle Beach to Irvine?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Irvine?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $91). Flying from Myrtle Beach to Irvine in December is currently the most expensive (average of $279). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Myrtle Beach to Irvine

Discover the top 4 airlines that operate flights from Myrtle Beach to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$194Average$336FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$312Average$474FlexibilityNo cancel feeOn-time71%
DeltaCheapest$312Average$504FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$351Average$447FlexibilityNo cancel feeOn-time63%

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