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$113+ Cheap flights from Myrtle Beach (MYR) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — LAX
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Irvine

Cheapest flights from Myrtle Beach to Irvine
Explore the most affordable flight options available from Myrtle Beach to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/49:09 am
MYR
-
LAX
2 stops25h 06m
Spirit Airlines
Tue 3/108:20 am
LAX
-
MYR
1 stop27h 35m
Spirit Airlines
Deal found 2/11$221
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:28 pm
MYR
-
LAX
1 stop8h 28m
Multiple Airlines
Sat 4/1111:59 pm
LAX
-
MYR
1 stop7h 06m
Multiple Airlines
Deal found 2/10$222
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1612:50 pm
MYR
-
LAX
1 stop8h 49m
Multiple Airlines
Sat 5/3011:55 pm
LAX
-
MYR
1 stop7h 10m
Multiple Airlines
Deal found 2/12$228
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:28 pm
MYR
-
LAX
1 stop8h 28m
Spirit Airlines
Mon 3/3011:30 pm
LAX
-
MYR
1 stop15h 03m
Spirit Airlines
Deal found 2/10$250
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:58 am
MYR
-
LAX
2 stops39h 44m
Multiple Airlines
Tue 4/148:18 am
LAX
-
MYR
1 stop27h 16m
Multiple Airlines
Deal found 2/10$252
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:28 pm
MYR
-
LAX
1 stop32h 28m
Spirit Airlines
Tue 4/148:18 am
LAX
-
MYR
1 stop27h 16m
Spirit Airlines
Deal found 2/10$253
This Expedia deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:28 pm
MYR
-
LAX
2 stops17h 38m
Multiple Airlines
Sat 4/411:59 pm
LAX
-
MYR
1 stop7h 06m
Multiple Airlines
Deal found 2/11$254
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1612:50 pm
MYR
-
LAX
1 stop8h 49m
Multiple Airlines
Sat 4/258:54 pm
LAX
-
MYR
1 stop11h 54m
Multiple Airlines
Deal found 2/11$257

Find flight deals from Myrtle Beach to Irvine

Keep the following information in mind while searching for Myrtle Beach to Irvine flight deals. Data was last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$113
(Super.com)

Popular in

March

Cheapest in

August

Average price

$446
Provider with most accurate pricing for Myrtle Beach Intl-Los Angeles flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Los Angeles flights.
Search Deals
From Myrtle Beach Intl to Irvine
Search Deals
One-way flight from Myrtle Beach Intl to Irvine
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Irvine that are best for you.

Fly from

Myrtle Beach

Fly to

Irvine

Route

Depart

Return

Price

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 3/20

6:28 pm-11:56 pm

1 stop8h 28m

Los Angeles

Mon 3/30

11:30 pm-5:33 pm

1 stop15h 03m

$250

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Sat 3/14

4:40 pm-11:56 pm

1 stop10h 16m

Los Angeles

Mon 3/16

11:30 pm-5:33 pm

1 stop15h 03m

$268

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Fri 5/8

7:31 pm-10:46 pm

1 stop30h 15m

Los Angeles

Tue 5/12

8:05 am-2:34 pm

1 stop27h 29m

$272

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 4/15

7:51 pm-11:51 pm

1 stop31h 00m

Los Angeles

Mon 4/20

8:05 am-8:58 am

1 stop21h 53m

$273

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 4/6

6:28 pm-9:06 am

2 stops17h 38m

Los Angeles

Mon 4/13

1:11 am-5:33 pm

2 stops13h 22m

$273

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 3/4

9:09 am-7:15 am

2 stops25h 06m

Los Angeles

Tue 3/10

8:20 am-2:55 pm

1 stop27h 35m

$277

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Sat 3/28

6:28 pm-11:56 pm

1 stop8h 28m

Los Angeles

Sat 4/4

11:59 pm-10:05 am

1 stop7h 06m

$286

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Wed 4/1

6:28 pm-11:56 pm

1 stop8h 28m

$113

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 4/27

3:20 pm-6:39 pm

1 stop30h 19m

$130

Myrtle BeachLos Angeles

MYR - LAX

MYRLAX

Myrtle Beach Intl

Mon 4/13

6:28 pm-9:02 pm

1 stop29h 34m

$131

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 15 results
1
2

Best time to book a flight from Myrtle Beach to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Irvine

What is the cheapest month to book a flight from Myrtle Beach to Irvine?

Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $102). Flying from Myrtle Beach to Irvine in December is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated February 13, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Myrtle Beach to Irvine to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,283 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,283 reviews
Southwest
8.0
Very good
4,283 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,191 reviews
Southwest
8.0
Very good
4,283 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,277 reviews
Southwest
8.0
Very good
4,283 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,451 reviews
Southwest
8.0
Very good
4,283 reviews

Overall

8.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Irvine?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Irvine. 4 airlines have flights from Myrtle Beach Intl to Irvine on a regular basis. Booking flights from Myrtle Beach Intl to Irvine should not be difficult; the airport handles an average of 0 outbound flights to Irvine per day.

  • How long is the flight from Myrtle Beach to Irvine?

    Airlines like Spirit Airlines fly from Myrtle Beach to Irvine in about 8h 28m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 2251 mi.

  • What are the cheapest airlines to fly from Myrtle Beach to Irvine one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $101. Users have also found prices from $132 and $156 on American Airlines and Southwest, respectively.

  • Can I find deals for flights from Myrtle Beach to Irvine that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Irvine.

  • Can I find deals for business class flights from Myrtle Beach to Irvine?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Irvine?

    Currently, May is the cheapest month in which you can book a flight from Myrtle Beach to Irvine (average of $102). Flying from Myrtle Beach to Irvine in December is currently the most expensive (average of $272). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Myrtle Beach to Irvine

Discover the top 4 airlines that operate flights from Myrtle Beach to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$194Average$336FlexibilityNo cancel feeOn-time65%
DeltaCheapest$223Average$488FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$312Average$472FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$351Average$447FlexibilityNo cancel feeOn-time63%

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