HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$90+ Cheap flights from Charleston (CHS) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Charleston to Iowa

Cheapest flights from Charleston to Iowa
Explore the most affordable flight options available from Charleston to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:53 pmCHS - CID
1 stop5h 06mAmerican Airlines
Wed 12/31:28 pmCID - CHS
1 stop7h 44mAmerican Airlines
Deal found 10/26$274
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:28 pmCHS - CID
1 stop5h 10mDelta
Sat 11/155:54 amCID - CHS
1 stop6h 11mDelta
Deal found 10/28$279
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:21 pmCHS - MLI
1 stop8h 42mAmerican Airlines
Wed 11/125:22 pmMLI - CHS
1 stop5h 03mAmerican Airlines
Deal found 10/26$289
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:11 pmCHS - DSM
1 stop21h 44mMultiple Airlines
Sun 11/1610:50 amDSM - CHS
1 stop10h 52mMultiple Airlines
Deal found 10/27$301
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:38 pmCHS - MLI
1 stop5h 40mUnited Airlines
Sat 11/156:35 amMLI - CHS
1 stop6h 20mUnited Airlines
Deal found 10/28$309
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:15 amCHS - CID
1 stop5h 20mUnited Airlines
Sat 11/158:00 amCID - CHS
1 stop4h 55mUnited Airlines
Deal found 10/27$329
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:15 amCHS - MLI
1 stop6h 35mUnited Airlines
Sat 11/1510:50 amMLI - CHS
1 stop7h 33mUnited Airlines
Deal found 10/27$329
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:31 amCHS - OMA
1 stop6h 44mDelta
Sat 12/137:00 amOMA - CHS
1 stop5h 05mDelta
Deal found 10/27$332
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:25 amCHS - DSM
1 stop6h 13mDelta
Tue 12/2310:29 amDSM - CHS
1 stop4h 42mDelta
Deal found 10/28$334
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:00 amCHS - OMA
2 stops9h 35mSouthwest
Sat 12/1312:45 pmOMA - CHS
1 stop4h 45mSouthwest
Deal found 10/27$337
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:10 amCHS - OMA
2 stops9h 32mAmerican Airlines
Sat 12/136:00 amOMA - CHS
2 stops8h 35mAmerican Airlines
Deal found 10/27$342
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:51 pmCHS - DSM
1 stop5h 55mDelta
Mon 11/247:46 amDSM - CHS
1 stop8h 32mDelta
Deal found 10/28$344

Cheap flight deals from Charleston to Iowa

Keep the following information in mind while searching for Charleston to Iowa flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$90
(Kiwi.com)

Popular in

February

Cheapest in

January

Average price

$392
Provider with most accurate pricing for Charleston-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Des Moines flights.
Search Deals
From Charleston to Iowa
Search Deals
One-way flight from Charleston to Iowa
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($112 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Charleston to Iowa that are best for you.

Fly from

Charleston

Fly to

Iowa

Route

Depart

Return

Price

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Wed 4/1

4:30 pm-10:34 pm

1 stop7h 04m

Moline Quad-City

Sat 4/4

5:55 am-11:25 am

1 stop4h 30m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Wed 11/26

7:53 pm-11:59 pm

1 stop5h 06m

Cedar Rapids

Wed 12/3

1:28 pm-10:12 pm

1 stop7h 44m

$274

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Tue 11/11

6:28 pm-10:38 pm

1 stop5h 10m

Cedar Rapids

Sat 11/15

5:54 am-1:05 pm

1 stop6h 11m

$279

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Sat 11/8

3:21 pm-11:03 pm

1 stop8h 42m

Moline Quad-City

Wed 11/12

5:22 pm-11:25 pm

1 stop5h 03m

$289

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Wed 4/15

3:10 pm-10:19 pm

1 stop8h 09m

Cedar Rapids

Sat 4/18

12:05 pm-11:41 pm

2 stops10h 36m

$299

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 11/13

6:11 pm-2:55 pm

1 stop21h 44m

Des Moines

Sun 11/16

10:50 am-10:42 pm

1 stop10h 52m

$301

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 2/26

2:05 pm-8:03 pm

1 stop6h 58m

Des Moines

Tue 3/3

10:15 am-6:02 pm

1 stop6h 47m

$313

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 2/26

2:05 pm-8:03 pm

1 stop6h 58m

Des Moines

Mon 3/2

7:00 am-2:11 pm

1 stop6h 11m

$313

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Wed 2/25

11:05 am-4:56 pm

1 stop6h 51m

Des Moines

Tue 3/3

5:45 am-11:25 am

1 stop4h 40m

$313

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Sat 2/28

6:30 am-10:23 am

1 stop4h 53m

Des Moines

Mon 3/2

5:15 pm-11:39 pm

1 stop5h 24m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 55 results
1
2
3
...
6

Best time to book a flight from Charleston to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Iowa

What is the cheapest month to book a flight from Charleston to Iowa?

Currently, September is the cheapest month in which you can book a flight from Charleston to Iowa (average of $162). Flying from Charleston to Iowa in December is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to IA?

Find hourly flight availability from Charleston to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s typically best to fly out from Charleston to Iowa in the evening. Doing so could potentially save you 37% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Charleston to Iowa, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Boarding

8.2

Overall

7.9

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Iowa?

    Charleston (CHS), located 10.2 mi from the city center, is the airport you fly out of when you book flights from Charleston to Iowa.

  • How long is the flight from Charleston to Iowa?

    Delta, American Airlines, and Southwest can get you from Charleston to Iowa in just under 5h 06m. Your travel time can differ by up to 4h 29m. The distance between Charleston and Iowa is about 890 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Charleston to Iowa one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $157. Users have also found prices from $157 and $274 on Delta and United Airlines, respectively.

  • What are the most popular routes from Charleston to Iowa?

    The most popular flight routes from Charleston to Iowa are Charleston - Omaha Eppley Airfield, Charleston - Des Moines and Charleston - Cedar Rapids.

  • Can I find deals for flights from Charleston to Iowa that include hotel bookings?

    Yes. In addition to deals on Charleston to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Iowa.

  • Can I find deals for business class flights from Charleston to Iowa?

    Yes. Cheapflights offers flight deals from Charleston to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Iowa (average of $162). Flying from Charleston to Iowa in December is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to LaGuardia flights
Charlotte to Newark flights
Charlotte to Dallas/Fort Worth flights
Charlotte to O'Hare Intl flights
Charlotte to Denver flights
Charlotte to Las Vegas flights
Charlotte to Orlando flights
Charlotte to Hobby flights
Charlotte to Boston flights
Charlotte to George Bush Intcntl flights
Charleston to John F Kennedy Intl flights
Charlotte to Miami flights
Charleston to Newark flights
Charlotte to Fort Lauderdale flights
Charlotte to Sky Harbor Intl flights
Charlotte to Los Angeles flights
Savannah to John F Kennedy Intl flights
Charlotte to Philadelphia flights
Greenville to Newark flights
Greenville to John F Kennedy Intl flights
Charlotte to Nashville flights
Savannah to Newark flights
Greenville to LaGuardia flights
Charleston to LaGuardia flights
Charleston to Fort Lauderdale flights
Charlotte to San Francisco flights
Charlotte to Love Field flights
Charlotte to Baltimore flights
Charlotte to Midway flights
Charleston to O'Hare Intl flights
Charlotte to Dulles Intl flights
Charlotte to New Orleans flights
Charlotte to Seattle flights
Charlotte to Salt Lake City flights
Myrtle Beach to Newark flights
Savannah to LaGuardia flights
Charlotte to Minneapolis flights
Charlotte to Reagan-National flights
Charlotte to Detroit flights
Charleston to Miami flights
Charlotte to Honolulu flights
Columbia to LaGuardia flights
Savannah to Dulles Intl flights
Charlotte to Atlanta flights
Charleston to Las Vegas flights
Charlotte to Ontario flights
Charlotte to Buffalo flights
Charlotte to San Diego flights
Charleston to Hobby flights

Top 2 airlines flying from Charleston to Iowa

Discover the top 2 airlines that operate flights from Charleston to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$409FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.