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$138+ Cheap flights from Charleston (CHS) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Charleston to Iowa

Cheapest flights from Charleston to Iowa
Explore the most affordable flight options available from Charleston to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/95:55 pm
CHS
-
MLI
1 stop5h 36m
Delta
Tue 6/165:00 pm
MLI
-
CHS
1 stop5h 57m
Delta
Deal found 1/27$269
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1110:15 am
CHS
-
MLI
1 stop5h 54m
United Airlines
Sun 2/158:15 am
MLI
-
CHS
1 stop4h 37m
United Airlines
Deal found 1/27$279
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1112:29 pm
CHS
-
MLI
2 stops10h 57m
American Airlines
Sun 2/156:00 am
MLI
-
CHS
2 stops6h 52m
American Airlines
Deal found 1/27$289
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:00 am
CHS
-
MLI
2 stops7h 53m
United Airlines
Tue 6/163:47 pm
MLI
-
CHS
1 stop5h 03m
United Airlines
Deal found 1/27$304
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/66:05 am
CHS
-
CID
1 stop5h 42m
United Airlines
Sun 2/86:35 am
CID
-
CHS
1 stop6h 27m
United Airlines
Deal found 1/27$339
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:35 am
CHS
-
DSM
1 stop7h 36m
American Airlines
Sat 5/166:00 am
DSM
-
CHS
1 stop4h 44m
American Airlines
Deal found 1/26$341
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/65:25 am
CHS
-
CID
2 stops7h 06m
Delta
Sun 2/85:35 am
CID
-
CHS
1 stop5h 13m
Delta
Deal found 1/27$344
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:00 am
CHS
-
MLI
1 stop6h 46m
United Airlines
Wed 2/188:15 am
MLI
-
CHS
1 stop4h 37m
United Airlines
Deal found 1/26$344
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:00 am
CHS
-
CID
1 stop7h 15m
United Airlines
Wed 2/1811:30 am
CID
-
CHS
2 stops11h 14m
United Airlines
Deal found 1/27$349
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:03 pm
CHS
-
OMA
1 stop6h 12m
American Airlines
Sun 3/85:17 pm
OMA
-
CHS
1 stop5h 38m
American Airlines
Deal found 1/27$372
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:30 am
CHS
-
CID
1 stop7h 22m
United Airlines
Tue 2/106:35 am
CID
-
CHS
1 stop6h 27m
United Airlines
Deal found 1/25$379
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:15 am
CHS
-
OMA
1 stop7h 09m
United Airlines
Mon 3/93:20 pm
OMA
-
CHS
1 stop4h 37m
United Airlines
Deal found 1/27$383

Find flight deals from Charleston to Iowa

Keep the following information in mind while searching for Charleston to Iowa flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$138
(Kiwi.com)

Popular in

February

Cheapest in

May

Average price

$321
Provider with most accurate pricing for Charleston-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Des Moines flights.
Search Deals
From Charleston to Iowa
Search Deals
One-way flight from Charleston to Iowa
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Charleston to Iowa that are best for you.

Fly from

Charleston

Fly to

Iowa

Route

Depart

Return

Price

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Tue 6/9

5:55 pm-10:31 pm

1 stop5h 36m

Moline Quad-City

Tue 6/16

5:00 pm-11:57 pm

1 stop5h 57m

$269

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Wed 2/11

10:15 am-3:09 pm

1 stop5h 54m

Moline Quad-City

Sun 2/15

8:15 am-1:52 pm

1 stop4h 37m

$279

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Wed 2/11

12:29 pm-10:26 pm

2 stops10h 57m

Moline Quad-City

Sun 2/15

6:00 am-1:52 pm

2 stops6h 52m

$289

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Tue 6/9

10:00 am-4:53 pm

2 stops7h 53m

Moline Quad-City

Tue 6/16

3:47 pm-9:50 pm

1 stop5h 03m

$304

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 5/14

5:30 am-10:16 am

1 stop5h 46m

Des Moines

Sat 5/16

2:15 pm-9:19 pm

1 stop6h 04m

$341

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Sat 2/14

6:00 am-12:15 pm

1 stop7h 15m

Cedar Rapids

Wed 2/18

1:10 pm-9:27 pm

1 stop7h 17m

$344

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Sat 2/14

6:00 am-11:46 am

1 stop6h 46m

Moline Quad-City

Wed 2/18

6:30 am-1:52 pm

1 stop6h 22m

$344

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 5/14

6:23 pm-11:29 pm

1 stop6h 06m

Des Moines

Sat 5/16

6:00 am-2:10 pm

2 stops7h 10m

$346

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Wed 5/13

7:15 am-1:48 pm

1 stop7h 33m

Des Moines

Sat 5/16

6:00 am-2:10 pm

2 stops7h 10m

$346

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

Sat 2/28

7:03 pm-12:15 am

1 stop6h 12m

Omaha Eppley Airfield

Sun 3/8

3:00 pm-11:01 pm

1 stop7h 01m

$372

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 36 results
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Best time to book a flight from Charleston to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Iowa

What is the cheapest month to book a flight from Charleston to Iowa?

Currently, September is the cheapest month in which you can book a flight from Charleston to Iowa (average of $162). Flying from Charleston to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Charleston to Iowa, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,123 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,123 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Iowa?

    Charleston (CHS), located 10.2 mi from the city center, is the airport you fly out of when you book flights from Charleston to Iowa.

  • How long is the flight from Charleston to Iowa?

    Delta, United Airlines, and American Airlines can get you from Charleston to Iowa in just under 5h 36m. Your travel time can differ by up to 5h 21m. The distance between Charleston and Iowa is about 824 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Charleston to Iowa?

    The most popular flight routes from Charleston to Iowa are Charleston - Omaha Eppley Airfield, Charleston - Des Moines and Charleston - Moline Quad-City.

  • Can I find deals for flights from Charleston to Iowa that include hotel bookings?

    Yes. In addition to deals on Charleston to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Iowa.

  • Can I find deals for business class flights from Charleston to Iowa?

    Yes. Cheapflights offers flight deals from Charleston to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Iowa?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Iowa (average of $162). Flying from Charleston to Iowa in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Iowa

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Top 2 airlines flying from Charleston to Iowa

Discover the top 2 airlines that operate flights from Charleston to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$233Average$360FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$418FlexibilityNo cancel feeOn-timeN/A

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