HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Iowa

$110+ Cheap flights from Charleston (CHS) to Iowa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Iowa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Iowa

Keep the following information in mind while searching for Charleston to Iowa flight deals. Data was last updated September 11, 2025.

Round-trip from

$219
(United Airlines)

One-way from

$110
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$275
From Charleston to Iowa
Search Deals
One-way flight from Charleston to Iowa
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($150 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Charleston to Iowa

Cheapest flights from Charleston to Iowa
Explore the most affordable flight options available from Charleston to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:02 amCHS - DSM
1 stop7h 17mUnited Airlines
Sat 10/1112:52 pmDSM - CHS
1 stop6h 16mUnited Airlines
Deal found 9/11$219
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:08 pmCHS - DSM
1 stop22h 42mMultiple Airlines
Sun 10/1910:41 amDSM - CHS
1 stop21h 25mMultiple Airlines
Deal found 9/11$228
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:40 amCHS - DSM
1 stop4h 25mDelta
Sat 10/115:15 pmDSM - CHS
1 stop5h 44mDelta
Deal found 9/11$237
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:45 pmCHS - OMA
1 stop14h 18mAmerican Airlines
Wed 10/297:10 amOMA - CHS
1 stop11h 05mAmerican Airlines
Deal found 9/11$239
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:05 amCHS - DSM
2 stops12h 50mSouthwest
Tue 11/116:15 amDSM - CHS
2 stops9h 50mSouthwest
Deal found 9/9$240
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/37:28 pmCHS - CID
1 stop4h 28mAmerican Airlines
Sun 10/56:01 amCID - CHS
1 stop4h 18mAmerican Airlines
Deal found 9/9$249
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:59 pmCHS - MLI
1 stop4h 25mDelta
Wed 11/125:08 pmMLI - CHS
1 stop4h 40mDelta
Deal found 9/9$249
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:00 pmCHS - CID
2 stops6h 41mDelta
Sun 11/25:00 amCID - CHS
1 stop4h 46mDelta
Deal found 9/10$254
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:48 pmCHS - MLI
1 stop5h 49mAmerican Airlines
Wed 11/129:48 amMLI - CHS
2 stops10h 18mAmerican Airlines
Deal found 9/9$254
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:03 pmCHS - OMA
1 stop4h 56mDelta
Mon 10/137:04 amOMA - CHS
1 stop7h 05mDelta
Deal found 9/10$257
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:59 pmCHS - CID
1 stop4h 44mDelta
Mon 9/295:57 amCID - CHS
1 stop6h 48mDelta
Deal found 9/10$259
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/314:36 pmCHS - DSM
1 stop5h 56mUnited Airlines
Tue 11/113:15 pmDSM - CHS
1 stop4h 53mUnited Airlines
Deal found 9/9$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Charleston to Iowa that are best for you.

Fly from

Charleston

Fly to

Iowa

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Tue 10/7

6:02 am-12:19 pm

1 stop7h 17m

Des Moines

Sat 10/11

12:52 pm-8:08 pm

1 stop6h 16m

$219

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Wed 10/15

7:41 pm-11:08 pm

1 stop4h 27m

Des Moines

Sat 10/18

6:44 am-1:23 pm

1 stop5h 39m

$219

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Tue 10/21

6:02 am-4:17 pm

2 stops11h 15m

Des Moines

Sat 10/25

12:52 pm-8:07 pm

1 stop6h 15m

$224

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Wed 10/8

6:40 am-10:05 am

1 stop4h 25m

Des Moines

Sat 10/11

5:15 pm-11:59 pm

1 stop5h 44m

$237

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Wed 10/15

7:00 am-2:35 pm

1 stop8h 35m

Des Moines

Sat 10/18

10:00 am-7:11 pm

1 stop8h 11m

$237

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

Fri 10/24

7:45 pm-9:03 am

1 stop14h 18m

Omaha Eppley Airfield

Wed 10/29

7:10 am-7:15 pm

1 stop11h 05m

$239

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Sat 11/8

11:10 am-4:24 pm

1 stop6h 14m

Moline Quad-City

Wed 11/12

5:08 pm-11:57 pm

1 stop5h 49m

$249

CharlestonMoline

CHS - MLI

CHSMLI

Charleston

Sat 11/8

1:48 pm-6:37 pm

1 stop5h 49m

Moline Quad-City

Wed 11/12

5:22 pm-11:25 pm

1 stop5h 03m

$249

CharlestonCedar Rapids

CHS - CID

CHSCID

Charleston

Sat 11/1

5:00 pm-10:41 pm

2 stops6h 41m

Cedar Rapids

Sun 11/2

5:00 am-10:46 am

1 stop4h 46m

$254

CharlestonOmaha

CHS - OMA

CHSOMA

Charleston

Thu 10/9

8:03 pm-11:59 pm

1 stop4h 56m

Omaha Eppley Airfield

Mon 10/13

7:04 am-3:09 pm

1 stop7h 05m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 46 results
1
2
3
...
5

Best time to book a flight from Charleston to Iowa

Have a flexible travel schedule? Discover the best time to fly to Iowa from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Iowa

What is the cheapest month to book a flight from Charleston to Iowa?

Currently, August is the cheapest month in which you can book a flight from Charleston to Iowa (average of $336). Flying from Charleston to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to IA?

Find hourly flight availability from Charleston to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to Iowa as you normally would.

Reviews of airlines servicing Iowa

Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Charleston to Iowa, such as Delta and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Iowa?

    Charleston (CHS), located 10.2 mi from the city center, is the airport you fly out of when you book flights from Charleston to Iowa.

  • How long is the flight from Charleston to Iowa?

    United Airlines, American Airlines, and Delta can get you from Charleston to Iowa in just under 4h 25m. Your travel time can differ by up to 2h 52m. The distance between Charleston and Iowa is about 956 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Charleston to Iowa one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $110. Users have also found prices from $249 and $332 on United Airlines and Delta, respectively.

  • What are the most popular routes from Charleston to Iowa?

    The most popular flight routes from Charleston to Iowa are Charleston - Omaha Eppley Airfield, Charleston - Des Moines and Charleston - Cedar Rapids.

  • Can I find deals for flights from Charleston to Iowa that include hotel bookings?

    Yes. In addition to deals on Charleston to Iowa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Iowa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Iowa.

  • Can I find deals for business class flights from Charleston to Iowa?

    Yes. Cheapflights offers flight deals from Charleston to Iowa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Iowa?

    Currently, August is the cheapest month in which you can book a flight from Charleston to Iowa (average of $336). Flying from Charleston to Iowa in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Iowa

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to John F Kennedy Intl flights
Charlotte to Newark flights
Charlotte to LaGuardia flights
Charlotte to Las Vegas flights
Charlotte to Denver flights
Charlotte to O'Hare Intl flights
Charlotte to Dallas/Fort Worth flights
Charlotte to Boston flights
Charlotte to Hobby flights
Charlotte to Fort Lauderdale flights
Charlotte to Orlando flights
Charlotte to Miami flights
Charlotte to George Bush Intcntl flights
Charlotte to Dulles Intl flights
Charlotte to Sky Harbor Intl flights
Charlotte to Baltimore flights
Charlotte to Los Angeles flights
Charlotte to Seattle flights
Charlotte to Love Field flights
Charlotte to Philadelphia flights
Charleston to Newark flights
Charleston to O'Hare Intl flights
Charlotte to Reagan-National flights
Charleston to John F Kennedy Intl flights
Charlotte to Minneapolis flights
Charleston to Denver flights
Savannah to John F Kennedy Intl flights
Greenville to Newark flights
Charlotte to Midway flights
Charleston to LaGuardia flights
Charlotte to Nashville flights
Charlotte to Salt Lake City flights
Charleston to Las Vegas flights
Greenville to John F Kennedy Intl flights
Charlotte to Atlanta flights
Greenville to LaGuardia flights
Charlotte to Austin flights
Savannah to Newark flights
Charlotte to New Orleans flights
Charlotte to Detroit flights
Charlotte to San Francisco flights
Charlotte to Honolulu flights
Charleston to Dallas/Fort Worth flights
Charlotte to Buffalo flights
Greenville to Dulles Intl flights
Greenville to Dallas/Fort Worth flights
Savannah to LaGuardia flights
Columbia to LaGuardia flights
Charleston to Boston flights
Charlotte to Ontario flights

Top 2 airlines flying from Charleston to Iowa

Discover the top 2 airlines that operate flights from Charleston to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$340FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$407FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.