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$125+ Cheap flights from Mississippi to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheap flight deals from Mississippi to Indianapolis

Keep the following information in mind while searching for Mississippi to Indianapolis flight deals. Data was last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

One-way from

$125
(Delta)

Popular in

February

Cheapest in

January

Average price

$386
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
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From Mississippi to Indianapolis
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One-way flight from Mississippi to Indianapolis
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Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Mississippi to Indianapolis

Cheapest flights from Mississippi to Indianapolis
Explore the most affordable flight options available from Mississippi to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:59 pmMOB - IND
1 stop5h 13mDelta
Mon 12/297:38 pmIND - MOB
1 stop4h 39mDelta
Deal found 11/2$249
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:03 pmGPT - IND
1 stop5h 23mDelta
Sat 11/296:00 amIND - GPT
1 stop4h 49mDelta
Deal found 11/1$249
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:09 pmBTR - IND
1 stop4h 46mUnited Airlines
Fri 12/511:50 amIND - BTR
1 stop6h 38mUnited Airlines
Deal found 10/31$266
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:55 pmMEM - IND
2 stops25h 25mMultiple Airlines
Fri 11/219:32 amIND - MEM
1 stop24h 30mMultiple Airlines
Deal found 11/1$275
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:07 amBTR - IND
1 stop4h 46mUnited Airlines
Wed 11/196:45 amIND - BTR
1 stop7h 37mUnited Airlines
Deal found 10/31$279
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/157:15 amGPT - IND
1 stop4h 56mAmerican Airlines
Wed 11/195:26 amIND - GPT
1 stop8h 11mAmerican Airlines
Deal found 10/31$279
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:15 amMEM - IND
1 stop11h 56mAmerican Airlines
Sun 12/287:33 pmIND - MEM
1 stop5h 26mAmerican Airlines
Deal found 11/1$280
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:26 pmGPT - IND
1 stop5h 00mAmerican Airlines
Mon 12/810:30 amIND - GPT
2 stops7h 32mAmerican Airlines
Deal found 11/1$283
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:30 pmMEM - IND
2 stops29h 48mMultiple Airlines
Mon 11/249:29 pmIND - MEM
1 stop12h 33mMultiple Airlines
Deal found 10/30$291
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/113:56 pmBTR - IND
1 stop6h 48mUnited Airlines
Tue 12/27:00 amIND - BTR
1 stop7h 14mUnited Airlines
Deal found 11/1$294
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:48 amJAN - IND
1 stop6h 26mDelta
Sat 12/65:34 pmIND - JAN
1 stop6h 28mDelta
Deal found 11/1$297
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amBTR - IND
1 stop6h 25mDelta
Tue 11/182:20 pmIND - BTR
1 stop4h 48mDelta
Deal found 10/31$309

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Mississippi to Indianapolis that are best for you.

Fly from

Mississippi

Fly to

Indianapolis

Route

Depart

Return

Price

MobileIndianapolis

MOB - IND

MOBIND

Mobile

Tue 12/23

5:59 pm-12:12 am

1 stop5h 13m

Indianapolis

Mon 12/29

7:38 pm-11:17 pm

1 stop4h 39m

$249

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Fri 2/20

6:00 pm-11:57 pm

1 stop4h 57m

Indianapolis

Tue 2/24

6:00 am-9:41 am

1 stop4h 41m

$249

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Tue 11/25

6:03 pm-12:26 am

1 stop5h 23m

Indianapolis

Sat 11/29

6:00 am-9:49 am

1 stop4h 49m

$249

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Tue 12/2

2:53 pm-9:42 pm

1 stop5h 49m

Indianapolis

Mon 12/8

6:42 pm-10:03 pm

1 stop4h 21m

$249

Baton RougeIndianapolis

BTR - IND

BTRIND

Baton Rouge Ryan

Fri 11/28

6:09 pm-11:55 pm

1 stop4h 46m

Indianapolis

Fri 12/5

11:50 am-5:28 pm

1 stop6h 38m

$266

MobileIndianapolis

MOB - IND

MOBIND

Mobile

Wed 4/15

7:15 pm-11:58 pm

1 stop3h 43m

Indianapolis

Sat 4/18

6:25 pm-10:55 pm

1 stop5h 30m

$274

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Mon 11/17

8:55 pm-11:20 pm

2 stops25h 25m

Indianapolis

Fri 11/21

9:32 am-9:02 am

1 stop24h 30m

$275

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Sat 11/15

7:15 am-1:11 pm

1 stop4h 56m

Indianapolis

Wed 11/19

5:26 am-12:37 pm

1 stop8h 11m

$279

Baton RougeIndianapolis

BTR - IND

BTRIND

Baton Rouge Ryan

Sat 11/15

5:07 am-10:53 am

1 stop4h 46m

Indianapolis

Wed 11/19

6:45 am-1:22 pm

1 stop7h 37m

$279

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 12/24

9:15 am-10:11 pm

1 stop11h 56m

Indianapolis

Sun 12/28

7:33 pm-11:59 pm

1 stop5h 26m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 48 results
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Best time to book a flight from Mississippi to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indianapolis

What is the cheapest month to book a flight from Mississippi to Indianapolis?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $144). Flying from Mississippi to Indianapolis in November is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IND?

Find hourly flight availability from Mississippi to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

One of the essential ways to save on airfare from Mississippi to Indianapolis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 38% on airfare.

How much does it cost to fly round-trip from Mississippi to Indianapolis?

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Mississippi?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Mississippi to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Mississippi to Indianapolis?

    A quick flight from Mississippi to Indianapolis can take about 4h 46m. Delta provides one of the quickest options available for as low as $266. Mississippi and Indianapolis are separated by a distance of 690 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mississippi to Indianapolis one-way?

    The cheapest airlines for a one-way flight from Mississippi to Indianapolis are Delta ($125), United Airlines ($125), and American Airlines ($185).

  • What are the most popular routes from Mississippi to Indianapolis?

    The most popular flight routes from Mississippi to Indianapolis are Memphis - Indianapolis, Baton Rouge Ryan - Indianapolis and Mobile - Indianapolis.

  • Can I find deals for flights from Mississippi to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indianapolis.

  • Can I find deals for business class flights from Mississippi to Indianapolis?

    Yes. Cheapflights offers flight deals from Mississippi to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indianapolis?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $144). Flying from Mississippi to Indianapolis in November is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Anderson
Kokomo
Bloomington
Plainfield
Franklin
Carmel
Crawfordsville
Speedway

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Alternative routes for Mississippi to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Indianapolis

Discover the top 3 airlines that operate flights from Mississippi to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$183Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$343FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$316Average$381FlexibilityNo cancel feeOn-time63%

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