HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$122+ Cheap flights from Mississippi to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Indianapolis

Keep the following information in mind while searching for Mississippi to Indianapolis flight deals. Data was last updated September 16, 2025.

Round-trip from

$221
(Kiwi.com)

One-way from

$122
(Kiwi.com)

Popular in

February

Cheapest in

January

Average price

$622
From Mississippi to Indianapolis
Search Deals
One-way flight from Mississippi to Indianapolis
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Mississippi to Indianapolis

Cheapest flights from Mississippi to Indianapolis
Explore the most affordable flight options available from Mississippi to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:30 pmMEM - IND
1 stop13h 47mMultiple Airlines
Mon 10/66:05 pmIND - MEM
1 stop26h 40mMultiple Airlines
Deal found 9/14$221
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/58:20 pmMEM - IND
1 stop15h 57mMultiple Airlines
Tue 10/76:20 pmIND - MEM
2 stops26h 25mMultiple Airlines
Deal found 9/16$229
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amMEM - IND
1 stop8h 42mAmerican Airlines
Sat 11/1510:30 amIND - MEM
1 stop11h 48mAmerican Airlines
Deal found 9/15$235
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:19 pmMEM - IND
1 stop16h 08mSpirit Airlines
Sun 11/95:49 amIND - MEM
1 stop10h 25mSpirit Airlines
Deal found 9/15$237
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/94:08 pmMEM - IND
1 stop14h 53mMultiple Airlines
Mon 10/2010:06 pmIND - MEM
1 stop22h 39mMultiple Airlines
Deal found 9/13$248
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:00 amMEM - IND
1 stop12h 22mMultiple Airlines
Sat 10/49:27 pmIND - MEM
1 stop23h 03mMultiple Airlines
Deal found 9/15$251
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:52 pmMEM - IND
2 stops19h 41mSpirit Airlines
Sat 11/1510:32 amIND - MEM
1 stop5h 42mSpirit Airlines
Deal found 9/15$253
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:00 amMEM - IND
1 stop12h 22mMultiple Airlines
Sun 10/196:40 pmIND - MEM
2 stops50h 05mMultiple Airlines
Deal found 9/14$258
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:40 amMOB - IND
1 stop4h 43mAmerican Airlines
Sat 10/46:52 pmIND - MOB
1 stop5h 10mAmerican Airlines
Deal found 9/15$259
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:30 amMEM - IND
2 stops9h 15mSouthwest
Sat 11/156:30 amIND - MEM
1 stop5h 40mSouthwest
Deal found 9/16$262
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/28:30 pmMEM - IND
1 stop13h 47mMultiple Airlines
Sun 10/51:57 pmIND - MEM
1 stop5h 34mMultiple Airlines
Deal found 9/15$263
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:56 pmBTR - IND
1 stop6h 48mUnited Airlines
Sun 11/96:45 amIND - BTR
1 stop5h 33mUnited Airlines
Deal found 9/15$264

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Mississippi to Indianapolis that are best for you.

Fly from

Mississippi

Fly to

Indianapolis

Route

Depart

Return

Price

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 11/12

6:00 am-3:42 pm

1 stop8h 42m

Indianapolis

Sat 11/15

10:30 am-9:18 pm

1 stop11h 48m

$235

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 10/15

7:00 am-11:04 pm

1 stop15h 04m

Indianapolis

Fri 10/24

10:23 pm-11:08 pm

1 stop25h 45m

$237

GulfportIndianapolis

GPT - IND

GPTIND

Gulfport Biloxi Regional

Sat 2/21

3:00 pm-8:04 pm

1 stop4h 04m

Indianapolis

Tue 2/24

9:55 am-1:37 pm

1 stop4h 42m

$249

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 11/12

3:52 pm-12:33 pm

2 stops19h 41m

Indianapolis

Sat 11/15

10:32 am-3:14 pm

1 stop5h 42m

$253

MobileIndianapolis

MOB - IND

MOBIND

Mobile

Tue 9/30

6:40 am-12:23 pm

1 stop4h 43m

Indianapolis

Sat 10/4

6:52 pm-11:02 pm

1 stop5h 10m

$259

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 11/12

7:30 am-12:10 pm

1 stop3h 40m

Indianapolis

Sat 11/15

6:40 am-1:20 pm

2 stops7h 40m

$262

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Thu 10/2

8:30 pm-11:17 am

1 stop13h 47m

Indianapolis

Sun 10/5

6:40 pm-11:08 pm

2 stops29h 28m

$262

Baton RougeIndianapolis

BTR - IND

BTRIND

Baton Rouge Ryan

Sat 11/8

3:56 pm-11:44 pm

1 stop6h 48m

Indianapolis

Sun 11/9

6:45 am-11:18 am

1 stop5h 33m

$264

MobileIndianapolis

MOB - IND

MOBIND

Mobile

Tue 9/30

12:45 pm-11:44 pm

2 stops9h 59m

Indianapolis

Sat 10/4

5:24 pm-9:48 pm

1 stop5h 24m

$264

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Fri 11/7

4:19 pm-3:35 pm

2 stops22h 16m

Indianapolis

Sun 11/9

5:49 am-3:14 pm

1 stop10h 25m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Mississippi to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indianapolis

What is the cheapest month to book a flight from Mississippi to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $286). Flying from Mississippi to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IND?

Find hourly flight availability from Mississippi to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Indianapolis as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Mississippi?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Mississippi to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Mississippi to Indianapolis?

    A quick flight from Mississippi to Indianapolis can take about 4h 04m. American Airlines provides one of the quickest options available for as low as $249. Mississippi and Indianapolis are separated by a distance of 661 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mississippi to Indianapolis one-way?

    The cheapest airlines for a one-way flight from Mississippi to Indianapolis are Spirit Airlines ($122), Delta ($199), and American Airlines ($199).

  • What are the most popular routes from Mississippi to Indianapolis?

    The most popular flight routes from Mississippi to Indianapolis are Memphis - Indianapolis, Jackson-Evers Intl - Indianapolis and Baton Rouge Ryan - Indianapolis.

  • Can I find deals for flights from Mississippi to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indianapolis.

  • Can I find deals for business class flights from Mississippi to Indianapolis?

    Yes. Cheapflights offers flight deals from Mississippi to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $286). Flying from Mississippi to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Muncie
Terre Haute
Noblesville
Fishers
Anderson
Kokomo
Greenwood
Bloomington
Franklin
Plainfield
Carmel
Crawfordsville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
Newark to O'Hare Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Dallas/Fort Worth to Midway flights
Reagan-National to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
Seattle to O'Hare Intl flights
Atlanta to O'Hare Intl flights
Philadelphia to O'Hare Intl flights
Baltimore to O'Hare Intl flights
Denver to O'Hare Intl flights
Boston to O'Hare Intl flights
John F Kennedy Intl to Midway flights
Ontario to O'Hare Intl flights
LaGuardia to Midway flights
Newark to Midway flights
Atlanta to Midway flights
Los Angeles to Midway flights
Santa Ana to O'Hare Intl flights
Sky Harbor Intl to O'Hare Intl flights
Austin to O'Hare Intl flights
Dulles Intl to Midway flights
Baltimore to Midway flights
Hobby to O'Hare Intl flights
Raleigh to O'Hare Intl flights
Philadelphia to Midway flights
LaGuardia to Cincinnati flights
Charlotte to O'Hare Intl flights
Minneapolis to Midway flights
LaGuardia to Indianapolis flights
John F Kennedy Intl to Cincinnati flights
Minneapolis to O'Hare Intl flights
John F Kennedy Intl to Indianapolis flights
Portland to O'Hare Intl flights
San Diego to O'Hare Intl flights
Tampa to O'Hare Intl flights
Love Field to O'Hare Intl flights
Boston to Cincinnati flights
San Francisco to Midway flights
Burbank to O'Hare Intl flights
Miami to O'Hare Intl flights
Hartford to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Orlando to O'Hare Intl flights
San Jose to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Newark to Cincinnati flights

Top 3 airlines flying from Mississippi to Indianapolis

Discover the top 3 airlines that operate flights from Mississippi to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$236Average$337FlexibilityNo cancel feeOn-time71%
DeltaCheapest$238Average$350FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$316Average$376FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.