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$103+ Cheap flights from Mississippi to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — IND
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Mississippi to Indianapolis

Cheapest flights from Mississippi to Indianapolis
Explore the most affordable flight options available from Mississippi to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:27 amMOB - IND
1 stop7h 08mAmerican Airlines
Thu 1/16:03 amIND - MOB
1 stop5h 22mAmerican Airlines
Deal found 12/16$324
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amJAN - IND
1 stop7h 49mUnited Airlines
Sun 1/46:20 amIND - JAN
1 stop6h 06mUnited Airlines
Deal found 12/16$351
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/194:34 pmBTR - IND
1 stop4h 34mAmerican Airlines
Tue 12/235:29 amIND - BTR
1 stop5h 10mAmerican Airlines
Deal found 12/16$354
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:58 pmGPT - IND
1 stop5h 00mAmerican Airlines
Mon 12/228:11 pmIND - GPT
1 stop5h 01mAmerican Airlines
Deal found 12/15$354
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amMOB - IND
2 stops11h 02mUnited Airlines
Sun 1/45:45 amIND - MOB
1 stop5h 58mUnited Airlines
Deal found 12/16$357
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amMEM - IND
1 stop5h 11mDelta
Sun 1/46:00 amIND - MEM
1 stop3h 45mDelta
Deal found 12/16$381
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:35 amMEM - IND
1 stop5h 28mUnited Airlines
Sun 1/45:05 pmIND - MEM
1 stop5h 41mUnited Airlines
Deal found 12/16$411
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:08 pmMEM - IND
1 stop19h 15mMultiple Airlines
Sun 1/45:06 pmIND - MEM
2 stops19h 24mMultiple Airlines
Deal found 12/16$429
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:34 pmBTR - IND
1 stop7h 04mAmerican Airlines
Tue 12/235:29 amIND - BTR
1 stop5h 10mAmerican Airlines
Deal found 12/17$434
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:17 pmMOB - IND
1 stop4h 09mDelta
Mon 12/227:00 amIND - MOB
1 stop5h 31mDelta
Deal found 12/15$434
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:34 pmBTR - IND
1 stop7h 04mAmerican Airlines
Wed 12/2411:52 amIND - BTR
1 stop4h 58mAmerican Airlines
Deal found 12/17$444
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/183:03 pmMOB - IND
1 stop6h 08mAmerican Airlines
Mon 12/228:11 pmIND - MOB
1 stop4h 45mAmerican Airlines
Deal found 12/15$449

Find flight deals from Mississippi to Indianapolis

Keep the following information in mind while searching for Mississippi to Indianapolis flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$189
(Kiwi.com)

One-way from

$103
(Priceline)

Popular in

February

Cheapest in

December

Average price

$263
Provider with most accurate pricing for Jackson-Evers Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Indianapolis flights.
Search Deals
From Mississippi to Indianapolis
Search Deals
One-way flight from Mississippi to Indianapolis
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mississippi to Indianapolis that are best for you.

Fly from

Mississippi

Fly to

Indianapolis

Route

Depart

Return

Price

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 1/14

11:44 am-1:15 pm

1 stop24h 31m

Indianapolis

Wed 1/21

12:21 pm-10:49 am

1 stop23h 28m

$189

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Fri 1/9

11:44 am-9:43 am

1 stop20h 59m

Indianapolis

Sun 1/11

2:12 pm-10:49 am

1 stop21h 37m

$201

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Sun 1/11

11:44 am-12:46 pm

1 stop24h 02m

Indianapolis

Sat 1/17

11:55 am-10:49 am

1 stop23h 54m

$206

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Fri 1/16

11:44 am-11:00 am

1 stop22h 16m

Indianapolis

Fri 1/23

8:26 pm-10:49 am

2 stops15h 23m

$217

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Fri 2/6

3:40 pm-11:15 pm

1 stop6h 35m

Indianapolis

Tue 2/10

5:10 am-10:49 am

2 stops30h 39m

$229

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 2/18

11:14 am-7:23 pm

2 stops7h 09m

Indianapolis

Mon 2/23

8:18 pm-10:19 am

2 stops15h 01m

$242

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Wed 2/11

11:44 am-11:04 am

2 stops22h 20m

Indianapolis

Fri 2/13

10:48 pm-10:19 am

1 stop12h 31m

$257

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Fri 2/20

5:00 pm-10:11 am

2 stops16h 11m

Indianapolis

Sun 2/22

9:57 pm-10:19 am

1 stop13h 22m

$258

MemphisIndianapolis

MEM - IND

MEMIND

Memphis

Sat 1/17

4:24 pm-12:06 am

1 stop6h 42m

Indianapolis

Sun 1/18

6:00 am-9:22 am

1 stop4h 22m

$259

Baton RougeIndianapolis

BTR - IND

BTRIND

Baton Rouge Ryan

Thu 1/1

4:21 pm-10:11 pm

1 stop4h 50m

Indianapolis

Mon 1/5

7:25 am-1:48 pm

1 stop7h 23m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 49 results
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Best time to book a flight from Mississippi to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Indianapolis

What is the cheapest month to book a flight from Mississippi to Indianapolis?

Currently, March is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $143). Flying from Mississippi to Indianapolis in November is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to IND?

Find hourly flight availability from Mississippi to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Mississippi to Indianapolis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 38% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from Mississippi?

    Indianapolis (IND) is the airport you will fly into if you book a flight from Mississippi to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How long is the flight from Mississippi to Indianapolis?

    A quick flight from Mississippi to Indianapolis can take about 4h 50m. Spirit Airlines provides one of the quickest options available for as low as $264. Mississippi and Indianapolis are separated by a distance of 690 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Mississippi to Indianapolis?

    The most popular flight routes from Mississippi to Indianapolis are Memphis - Indianapolis, Baton Rouge Ryan - Indianapolis and Mobile - Indianapolis.

  • Can I find deals for flights from Mississippi to Indianapolis that include hotel bookings?

    Yes. In addition to deals on Mississippi to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Indianapolis.

  • Can I find deals for business class flights from Mississippi to Indianapolis?

    Yes. Cheapflights offers flight deals from Mississippi to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Indianapolis?

    Currently, March is the cheapest month in which you can book a flight from Mississippi to Indianapolis (average of $143). Flying from Mississippi to Indianapolis in November is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Terre Haute
Muncie
Noblesville
Fishers
Greenwood
Plainfield
Anderson
Kokomo
Franklin
Carmel
Crawfordsville
Bloomington
Speedway

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Alternative routes for Mississippi to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to Indianapolis

Discover the top 2 airlines that operate flights from Mississippi to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$183Average$435FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$236Average$343FlexibilityNo cancel feeOn-time71%

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