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$68+ Cheap flights from Myrtle Beach (MYR) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Indiana

Cheapest flights from Myrtle Beach to Indiana
Explore the most affordable flight options available from Myrtle Beach to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/33:59 pm
MYR
-
ORD
1 stop9h 41m
Spirit Airlines
Tue 3/108:16 pm
ORD
-
MYR
1 stop10h 57m
Spirit Airlines
Deal found 2/3$140
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:09 am
MYR
-
IND
1 stop13h 16m
Spirit Airlines
Wed 3/116:00 am
IND
-
MYR
1 stop8h 55m
Spirit Airlines
Deal found 2/2$142
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:54 pm
MYR
-
ORD
1 stop27h 46m
Spirit Airlines
Sun 3/16:51 pm
ORD
-
MYR
1 stop13h 07m
Spirit Airlines
Deal found 2/3$146
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:54 pm
MYR
-
ORD
1 stop12h 28m
Spirit Airlines
Mon 3/26:51 pm
ORD
-
MYR
1 stop19h 04m
Spirit Airlines
Deal found 2/2$147
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:09 am
MYR
-
ORD
1 stop11h 02m
Spirit Airlines
Mon 3/98:16 pm
ORD
-
MYR
1 stop10h 57m
Spirit Airlines
Deal found 2/2$150
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2710:09 am
MYR
-
IND
1 stop13h 16m
Spirit Airlines
Tue 3/36:00 am
IND
-
MYR
1 stop8h 55m
Spirit Airlines
Deal found 2/3$155
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/209:09 am
MYR
-
ORD
1 stop13h 04m
Spirit Airlines
Mon 2/236:51 pm
ORD
-
MYR
1 stop13h 07m
Spirit Airlines
Deal found 2/2$158
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:59 pm
MYR
-
IND
1 stop7h 26m
Spirit Airlines
Fri 3/66:00 am
IND
-
MYR
1 stop26h 58m
Spirit Airlines
Deal found 2/2$163
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:09 am
MYR
-
ORD
1 stop11h 02m
Multiple Airlines
Thu 3/129:15 am
ORD
-
MYR
1 stop7h 18m
Multiple Airlines
Deal found 2/3$164
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:49 pm
MYR
-
ORD
1 stop13h 31m
Spirit Airlines
Wed 3/186:10 pm
ORD
-
MYR
1 stop22h 23m
Spirit Airlines
Deal found 2/3$167
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:58 pm
MYR
-
MDW
1 stop16h 02m
Multiple Airlines
Mon 4/207:30 am
MDW
-
MYR
1 stop24h 28m
Multiple Airlines
Deal found 2/2$172
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:57 am
MYR
-
ORD
1 stop13h 43m
Spirit Airlines
Sat 3/217:31 pm
ORD
-
MYR
1 stop12h 21m
Spirit Airlines
Deal found 2/3$173

Find flight deals from Myrtle Beach to Indiana

Keep the following information in mind while searching for Myrtle Beach to Indiana flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$140
(Mytrip)

One-way from

$68
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$319

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From Myrtle Beach Intl to Indiana
Search Deals
One-way flight from Myrtle Beach Intl to Indiana
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($125 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Indiana.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Indiana that are best for you.

Fly from

Myrtle Beach

Fly to

Indiana

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 3/3

3:59 pm-12:40 am

1 stop9h 41m

Chicago O'Hare Intl

Tue 3/10

8:16 pm-8:13 am

1 stop10h 57m

$140

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 2/27

9:54 pm-9:22 am

1 stop12h 28m

Chicago O'Hare Intl

Mon 3/2

6:51 pm-2:55 pm

1 stop19h 04m

$147

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 3/5

9:09 am-7:11 pm

1 stop11h 02m

Chicago O'Hare Intl

Mon 3/9

8:16 pm-8:13 am

1 stop10h 57m

$150

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 3/2

3:59 pm-11:25 pm

1 stop7h 26m

Indianapolis

Fri 3/6

6:00 am-8:58 am

1 stop26h 58m

$163

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sun 3/15

6:28 pm-5:15 pm

1 stop23h 47m

Chicago O'Hare Intl

Wed 3/18

6:10 pm-5:33 pm

1 stop22h 23m

$164

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Fri 4/17

9:58 pm-1:00 pm

1 stop16h 02m

Chicago Midway

Mon 4/20

7:30 am-8:58 am

1 stop24h 28m

$172

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sat 3/7

11:57 am-12:40 am

1 stop13h 43m

Chicago O'Hare Intl

Sat 3/21

7:31 pm-8:52 am

1 stop12h 21m

$173

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Thu 3/5

9:09 am-7:23 pm

1 stop10h 14m

Indianapolis

Sun 3/8

8:18 pm-8:13 am

1 stop11h 55m

$174

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Mon 3/16

6:28 pm-10:32 pm

1 stop28h 04m

Indianapolis

Wed 3/18

6:00 am-2:32 pm

1 stop8h 32m

$179

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 2/27

10:09 am-11:25 pm

1 stop13h 16m

Indianapolis

Tue 3/3

3:12 pm-2:55 pm

2 stops23h 43m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 60 results
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Best time to book a flight from Myrtle Beach to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indiana

What is the cheapest month to book a flight from Myrtle Beach to Indiana?

Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Indiana (average of $45). Flying from Myrtle Beach to Indiana in April is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IN?

Find hourly flight availability from Myrtle Beach to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 4, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 32% on flights from Myrtle Beach to Indiana by exploring options for tickets in the evening.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated February 4, 2026.
Read through reviews of airlines operating flights from Myrtle Beach to Indiana, such as Delta, American Airlines, and Spirit Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,138 reviews
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,218 reviews
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,407 reviews
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Indiana?

    For a flight from Myrtle Beach to Indiana, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city.

  • How long is the flight from Myrtle Beach to Indiana?

    A quick flight from Myrtle Beach to Indiana can take about 4h 53m. Spirit Airlines provides one of the quickest options available for as low as $269. There are 520 mi between Myrtle Beach and Indiana. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Myrtle Beach to Indiana one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $38. However, be on the lookout for offers from Spirit Airlines and Delta, as they are both options that can get you from Myrtle Beach to Indiana for a low price.

  • What are the most popular routes from Myrtle Beach to Indiana?

    Most travelers choose Myrtle Beach Intl - Chicago O'Hare Intl, Myrtle Beach Intl - Chicago Midway or Myrtle Beach Intl - Indianapolis when deciding on the best route from Myrtle Beach to Indiana.

  • What are the cheapest flights from Myrtle Beach to Indiana?

    The cheapest flight price from Myrtle Beach to Indiana is $94. On average you can expect to pay $119. The most popular route, (Myrtle Beach Intl - Chicago O'Hare Intl), can usually be booked for $140.

  • Can I find deals for flights from Myrtle Beach to Indiana that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indiana.

  • Can I find deals for business class flights from Myrtle Beach to Indiana?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indiana?

    Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Indiana (average of $45). Flying from Myrtle Beach to Indiana in April is currently the most expensive (average of $251). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Indiana

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Top 3 airlines flying from Myrtle Beach to Indiana

Discover the top 3 airlines that operate flights from Myrtle Beach to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$83Average$174FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$248Average$390FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$406FlexibilityNo cancel feeOn-timeN/A

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