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$80+ Cheap flights from Myrtle Beach (MYR) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — IND
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from Myrtle Beach to Indiana

Cheapest flights from Myrtle Beach to Indiana
Explore the most affordable flight options available from Myrtle Beach to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Priceline deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Mon 12/87:20 amORD - MYR
1 stop5h 00mSpirit Airlines
Deal found 11/19$164
This Super.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:15 pmMYR - ORD
1 stop8h 33mSpirit Airlines
Mon 12/87:20 amORD - MYR
1 stop5h 00mSpirit Airlines
Deal found 11/19$167
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Sat 12/67:20 amORD - MYR
1 stop5h 00mSpirit Airlines
Deal found 11/20$168
This Expedia deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:15 amMYR - ORD
1 stop10h 48mSpirit Airlines
Sun 12/77:20 amORD - MYR
1 stop11h 12mSpirit Airlines
Deal found 11/18$169
This Super.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Wed 12/315:00 amORD - MYR
1 stop12h 08mSpirit Airlines
Deal found 11/19$174
This Cheapflightsfares deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Tue 12/165:00 amORD - MYR
1 stop11h 48mSpirit Airlines
Deal found 11/19$175
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:40 pmMYR - CVG
1 stop4h 13mDelta
Wed 12/1010:00 amCVG - MYR
1 stop3h 55mDelta
Deal found 11/18$177
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:37 pmMYR - CVG
1 stop3h 55mAmerican Airlines
Wed 12/1011:58 amCVG - MYR
2 stops7h 04mAmerican Airlines
Deal found 11/18$182
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:54 amMYR - ORD
1 stop11h 07mSpirit Airlines
Sun 12/712:09 pmORD - MYR
1 stop6h 23mSpirit Airlines
Deal found 11/20$183
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:54 amMYR - ORD
1 stop9h 45mSpirit Airlines
Wed 12/317:30 amORD - MYR
1 stop9h 38mSpirit Airlines
Deal found 11/19$186
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/39:46 amMYR - ORD
2 stops10h 00mMultiple Airlines
Sun 12/77:20 amORD - MYR
1 stop11h 12mMultiple Airlines
Deal found 11/18$206
This Priceline deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:15 pmMYR - IND
1 stop7h 20mSpirit Airlines
Tue 12/912:03 pmIND - MYR
1 stop5h 45mSpirit Airlines
Deal found 11/20$213

Cheap flight deals from Myrtle Beach to Indiana

Keep the following information in mind while searching for Myrtle Beach to Indiana flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$164
(Priceline)

One-way from

$80
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$361

Good one-way deal

$119 or less
Provider with most accurate pricing for Myrtle Beach Intl-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Indianapolis flights.
Search Deals
From Myrtle Beach Intl to Indiana
Search Deals
One-way flight from Myrtle Beach Intl to Indiana
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($186 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Indiana.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Indiana that are best for you.

Fly from

Myrtle Beach

Fly to

Indiana

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 12/4

9:54 am-8:01 pm

1 stop11h 07m

Chicago O'Hare Intl

Mon 12/8

7:20 am-1:20 pm

1 stop5h 00m

$164

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 12/5

2:15 pm-9:48 pm

1 stop8h 33m

Chicago O'Hare Intl

Mon 12/8

7:20 am-1:20 pm

1 stop5h 00m

$167

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 12/12

9:54 am-8:01 pm

1 stop11h 07m

Chicago O'Hare Intl

Tue 12/16

5:00 am-5:48 pm

1 stop11h 48m

$175

Myrtle BeachCincinnati

MYR - CVG

MYRCVG

Myrtle Beach Intl

Tue 12/9

2:40 pm-6:53 pm

1 stop4h 13m

Cincinnati Cinci./N. Kentucky

Wed 12/10

10:00 am-1:55 pm

1 stop3h 55m

$177

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 12/4

9:54 am-8:01 pm

1 stop11h 07m

Chicago O'Hare Intl

Sun 12/7

12:09 pm-7:32 pm

1 stop6h 23m

$183

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 2/6

9:53 am-10:37 pm

1 stop13h 44m

Chicago O'Hare Intl

Mon 2/9

7:29 am-7:20 pm

1 stop10h 51m

$184

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Mon 12/22

9:54 am-6:39 pm

1 stop9h 45m

Chicago O'Hare Intl

Wed 12/31

7:30 am-6:08 pm

1 stop9h 38m

$186

Myrtle BeachCincinnati

MYR - CVG

MYRCVG

Myrtle Beach Intl

Tue 12/9

7:30 am-3:33 pm

2 stops8h 03m

Cincinnati Cinci./N. Kentucky

Wed 12/10

6:43 am-1:29 pm

2 stops6h 46m

$187

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 12/3

6:15 am-4:03 pm

1 stop10h 48m

Chicago O'Hare Intl

Sun 12/7

7:41 pm-5:48 pm

3 stops21h 07m

$207

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Tue 12/23

9:54 am-10:43 pm

2 stops12h 49m

Indianapolis

Mon 1/5

4:51 pm-11:59 pm

1 stop7h 08m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 60 results
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Best time to book a flight from Myrtle Beach to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Indiana

What is the cheapest month to book a flight from Myrtle Beach to Indiana?

Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Indiana (average of $45). Flying from Myrtle Beach to Indiana in January is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to IN?

Find hourly flight availability from Myrtle Beach to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 26% on flights from Myrtle Beach to Indiana by exploring options for tickets at noon.

What is the cheapest day to fly from Myrtle Beach to Indiana?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Indiana. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Myrtle Beach to Indiana flight should consider departing on Tuesday at noon when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated November 20, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Indiana, such as Delta, American Airlines, and Spirit Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,158 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Indiana?

    For a flight from Myrtle Beach to Indiana, you will be flying from Myrtle Beach Intl. Myrtle Beach Intl (MYR) is just 2.1 mi from the center of the city.

  • How long is the flight from Myrtle Beach to Indiana?

    A quick flight from Myrtle Beach to Indiana can take about 4h 13m. Spirit Airlines provides one of the quickest options available for as low as $177. There are 489 mi between Myrtle Beach and Indiana. This flight may include one or multiple stops.

  • What are the most popular routes from Myrtle Beach to Indiana?

    Most travelers choose Myrtle Beach Intl - Chicago O'Hare Intl, Myrtle Beach Intl - Chicago Midway or Myrtle Beach Intl - Indianapolis when deciding on the best route from Myrtle Beach to Indiana.

  • What are the cheapest flights from Myrtle Beach to Indiana?

    The cheapest flight price from Myrtle Beach to Indiana is $94. On average you can expect to pay $119. The most popular route, (Myrtle Beach Intl - Chicago O'Hare Intl), can usually be booked for $167.

  • Can I find deals for flights from Myrtle Beach to Indiana that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Indiana.

  • Can I find deals for business class flights from Myrtle Beach to Indiana?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Indiana?

    Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Indiana (average of $45). Flying from Myrtle Beach to Indiana in January is currently the most expensive (average of $257). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Myrtle Beach to Indiana

Discover the top 3 airlines that operate flights from Myrtle Beach to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$146Average$192FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$248Average$404FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$406FlexibilityNo cancel feeOn-timeN/A

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