How long is the flight from Des Moines to Harrisburg?

Airlines like United Airlines and American Airlines fly from Des Moines to Harrisburg in about 5h 15m. The time it takes to get you to your destination can typically vary by up to 43m. Airlines will cover a distance of 886 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to Harrisburg round-trip?

Flying on United Airlines is currently your cheapest option to Harrisburg, with prices starting at $219. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $226 and $248, respectively. Users have found that United Airlines is 32% cheaper than the other options available to this destination.

In terms of precipitation, rainfall in Harrisburg ranges from 2.7 - 4.1 inches per month. May is typically the wettest month, when rainfall can reach 4.1 in. February is typically the driest time to visit Harrisburg when rainfall is around 2.7 in.

If weather is an important factor for your trip to Harrisburg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What are the most popular airlines that fly from Des Moines to Harrisburg?

The most popular airlines flying from Des Moines to Harrisburg are American Airlines, United Airlines and Delta. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from DSM to MDT?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Harrisburg as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Harrisburg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Harrisburg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Harrisburg flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Harrisburg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Harrisburg that include hotel bookings?

Yes. In addition to deals on Des Moines to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Harrisburg?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Harrisburg.

Can I find deals for business class flights from Des Moines to Harrisburg?

Yes. Cheapflights offers flight deals from Des Moines to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$196+ Flights from Des Moines to Harrisburg

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Cheap flight deals from Des Moines to Harrisburg

Cheapest flights from Des Moines to Harrisburg
Explore the most affordable flight options available from Des Moines to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Fri 12/266:46 pmDSM - MDT

1 stop4h 21mUnited Airlines

Tue 12/306:30 amMDT - DSM

1 stop5h 20mUnited Airlines

Deal found 12/10

$394

Sat 12/276:46 pmDSM - MDT

1 stop4h 21mUnited Airlines

Wed 12/316:15 amMDT - DSM

2 stops9h 18mUnited Airlines

Deal found 12/11

$399

Best flights from Des Moines to Harrisburg
Discover carefully curated flight deals from Des Moines to Harrisburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Sun 1/188:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Sat 1/245:26 pmMDT - DSM

1 stop5h 24mUnited Airlines

Deal found 12/10

$233

Sat 1/105:00 pmDSM - MDT

1 stop5h 58mAmerican Airlines

Mon 1/124:47 pmMDT - DSM

1 stop7h 21mAmerican Airlines

Deal found 12/12

$269

Fri 1/98:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Fri 1/163:10 pmMDT - DSM

1 stop7h 40mUnited Airlines

Deal found 12/11

$269

Fri 1/94:25 pmDSM - MDT

1 stop6h 12mAmerican Airlines

Mon 1/124:47 pmMDT - DSM

1 stop7h 21mAmerican Airlines

Deal found 12/11

$289

Thu 1/88:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Sat 1/103:10 pmMDT - DSM

1 stop7h 40mUnited Airlines

Deal found 12/11

$269

Thu 1/11:25 pmDSM - MDT

1 stop5h 06mAmerican Airlines

Tue 1/64:47 pmMDT - DSM

1 stop7h 21mAmerican Airlines

Deal found 12/10

$289

Sat 1/103:35 pmDSM - MDT

1 stop4h 30mUnited Airlines

Mon 1/1210:34 amMDT - DSM

2 stops11h 00mUnited Airlines

Deal found 12/10

$274

Thu 1/224:25 pmDSM - MDT

1 stop6h 12mAmerican Airlines

Sun 1/259:15 amMDT - DSM

1 stop7h 46mAmerican Airlines

Deal found 12/10

$294

Fri 1/98:00 amDSM - MDT

2 stops9h 59mUnited Airlines

Mon 1/1210:34 amMDT - DSM

2 stops11h 00mUnited Airlines

Deal found 12/10

$284

Last-minute flights from Des Moines to Harrisburg
Discover last-minute flight deals from Des Moines to Harrisburg. Data last updated December 12, 2025 and is based on user searches.

Thu 1/11:25 pmDSM - MDT

1 stop5h 06mAmerican Airlines

Tue 1/64:47 pmMDT - DSM

1 stop7h 21mAmerican Airlines

Deal found 12/10

$289

Fri 1/22:07 pmDSM - MDT

1 stop6h 55mAmerican Airlines

Tue 1/67:00 amMDT - DSM

2 stops9h 45mAmerican Airlines

Deal found 12/10

$299

Thu 1/83:35 pmDSM - MDT

1 stop4h 30mUnited Airlines

Sat 1/106:30 amMDT - DSM

2 stops10h 58mUnited Airlines

Deal found 12/11

$274

Fri 1/98:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Mon 1/125:30 pmMDT - DSM

1 stop5h 20mUnited Airlines

Deal found 12/10

$269

Fri 1/95:30 amDSM - MDT

2 stops10h 04mUnited Airlines

Fri 1/166:15 amMDT - DSM

2 stops9h 18mUnited Airlines

Deal found 12/11

$316

Sat 1/107:50 amDSM - MDT

2 stops10h 09mUnited Airlines

Mon 1/1210:34 amMDT - DSM

2 stops11h 00mUnited Airlines

Deal found 12/10

$310

Sun 1/188:00 amDSM - MDT

1 stop5h 15mUnited Airlines

Sat 1/245:26 pmMDT - DSM

1 stop5h 24mUnited Airlines

Deal found 12/10

$233

Thu 1/221:16 pmDSM - MDT

2 stops7h 44mAmerican Airlines

Sun 1/255:02 pmMDT - DSM

1 stop7h 06mAmerican Airlines

Deal found 12/11

$294

One-way flights from Des Moines to Harrisburg
Search for one-way flight options from Des Moines to Harrisburg. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Sun 1/184:42 pmDSM - MDT

1 stop5h 55mAmerican Airlines

Deal found 12/9

$196

Sat 12/202:45 pmDSM - MDT

1 stop23h 15mAllegiant Air

Deal found 12/10

$217

Sat 12/203:47 pmDSM - MDT

2 stops17h 29mMultiple Airlines

Deal found 12/10

$234

Thu 3/57:00 amDSM - MDT

1 stop6h 50mAmerican Airlines

Deal found 12/10

$239

Mon 12/222:11 pmDSM - MDT

1 stop19h 20mAllegiant Air

Deal found 12/10

$276

Thu 3/57:27 pmDSM - MDT

3 stops20h 09mMultiple Airlines

Deal found 12/9

$298

Sat 12/276:46 pmDSM - MDT

1 stop4h 21mUnited Airlines

Deal found 12/10

$314

Mon 12/224:03 pmDSM - MDT

3 stops46h 35mMultiple Airlines

Deal found 12/10

$351

Find flight deals from Des Moines to Harrisburg

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$233 (United Airlines)
One-way from	$196 (American Airlines)
Popular in	February
Cheapest in	October
Average price	$285

Provider with most accurate pricing for Des Moines-Harrisburg flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Harrisburg flights.

Search Deals

From Des Moines to Harrisburg

Search Deals

One-way flight from Des Moines to Harrisburg

Search Deals

Highest demand for flights based on searches. 11% potential increase in price ($41 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Harrisburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Sun 1/18

8:00 am-2:15 pm

1 stop5h 15m

Harrisburg

Sat 1/24

5:26 pm-9:50 pm

1 stop5h 24m

$233

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Sat 1/10

5:00 pm-11:58 pm

1 stop5h 58m

Harrisburg

Mon 1/12

4:47 pm-11:08 pm

1 stop7h 21m

$269

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Fri 1/9

8:00 am-2:15 pm

1 stop5h 15m

Harrisburg

Fri 1/16

3:10 pm-9:50 pm

1 stop7h 40m

$269

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Thu 1/8

8:00 am-2:15 pm

1 stop5h 15m

Harrisburg

Sat 1/10

3:10 pm-9:50 pm

1 stop7h 40m

$269

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Sat 1/10

3:35 pm-9:05 pm

1 stop4h 30m

Harrisburg

Mon 1/12

10:34 am-8:34 pm

2 stops11h 00m

$274

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Fri 1/9

8:00 am-6:59 pm

2 stops9h 59m

Harrisburg

Mon 1/12

10:34 am-8:34 pm

2 stops11h 00m

$284

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Fri 1/9

4:25 pm-11:37 pm

1 stop6h 12m

Harrisburg

Mon 1/12

4:47 pm-11:08 pm

1 stop7h 21m

$289

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Thu 1/1

1:25 pm-7:31 pm

1 stop5h 06m

Harrisburg

Tue 1/6

4:47 pm-11:08 pm

1 stop7h 21m

$289

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Thu 1/22

4:25 pm-11:37 pm

1 stop6h 12m

Harrisburg

Sun 1/25

9:15 am-4:01 pm

1 stop7h 46m

$294

Des MoinesHarrisburg

DSM - MDT

DSMMDT

Des Moines

Sun 1/18

4:42 pm-11:37 pm

1 stop5h 55m

$196

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 18 results

Compare providers for flights from Des Moines to Harrisburg

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Harrisburg in December.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Harrisburg flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Harrisburg flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Harrisburg flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Harrisburg flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Harrisburg flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Harrisburg

What is the cheapest month to book a flight from Des Moines to Harrisburg?

Currently, October is the cheapest month in which you can book a flight from Des Moines to Harrisburg (average of $205). Flying from Des Moines to Harrisburg in November is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Harrisburg

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Harrisburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,008 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,095 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,050 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Des Moines to Harrisburg?
Airlines like United Airlines and American Airlines fly from Des Moines to Harrisburg in about 5h 15m. The time it takes to get you to your destination can typically vary by up to 43m. Airlines will cover a distance of 886 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Des Moines to Harrisburg round-trip?
Flying on United Airlines is currently your cheapest option to Harrisburg, with prices starting at $219. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $226 and $248, respectively. Users have found that United Airlines is 32% cheaper than the other options available to this destination.
Can I find deals for flights from Des Moines to Harrisburg that include hotel bookings?
Yes. In addition to deals on Des Moines to Harrisburg flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Harrisburg?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Harrisburg.
Can I find deals for business class flights from Des Moines to Harrisburg?
Yes. Cheapflights offers flight deals from Des Moines to Harrisburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Harrisburg?
Currently, October is the cheapest month in which you can book a flight from Des Moines to Harrisburg (average of $205). Flying from Des Moines to Harrisburg in November is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Complete your trip

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Top 3 airlines flying from Des Moines to Harrisburg

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$219	Average$318	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$226	Average$381	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$248	Average$284	FlexibilityNo cancel fee	On-timeN/A

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$196+ Cheap flights from Des Moines to Harrisburg (DSM - MDT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Harrisburg with Cheapflights

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Cheap flight deals from Des Moines to Harrisburg

Cheapest flights from Des Moines to HarrisburgExplore the most affordable flight options available from Des Moines to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Des Moines to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Des Moines to Harrisburg

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Harrisburg that are best for you.

Compare providers for flights from Des Moines to Harrisburg

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Harrisburg in December.

Best time to book a flight from Des Moines to Harrisburg

Have a flexible travel schedule? Discover the best time to fly to Harrisburg from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Harrisburg

What is the cheapest month to book a flight from Des Moines to Harrisburg?

Reviews of airlines servicing Harrisburg

Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Harrisburg by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Harrisburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Des Moines to Harrisburg?

What are the cheapest airlines flying from Des Moines to Harrisburg round-trip?

Can I find deals for flights from Des Moines to Harrisburg that include hotel bookings?

How can I find direct flights from Des Moines to Harrisburg?

Can I find deals for business class flights from Des Moines to Harrisburg?

What is the cheapest month to book a flight from Des Moines to Harrisburg?

Traveling to a place near Harrisburg?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to Harrisburg

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Top 3 airlines flying from Des Moines to Harrisburg

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Cheapest flights from Des Moines to Harrisburg
Explore the most affordable flight options available from Des Moines to Harrisburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.