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Guadalajara

$131+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Des Moines to Guadalajara

Cheapest flights from Des Moines to Guadalajara
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:39 pmDSM - GDL
1 stop5h 59mAmerican Airlines
Sun 1/114:44 pmGDL - DSM
1 stop6h 39mAmerican Airlines
Deal found 12/26$876
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:30 pmDSM - GDL
2 stops36h 35mMultiple Airlines
Sun 1/49:35 amGDL - DSM
1 stop26h 21mMultiple Airlines
Deal found 12/26$996
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:20 pmDSM - GDL
1 stop30h 05mMultiple Airlines
Sat 1/37:50 pmGDL - DSM
2 stops40h 06mMultiple Airlines
Deal found 12/25$1,047
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:23 amDSM - GDL
2 stops11h 59mDelta
Sun 1/48:00 amGDL - DSM
2 stops12h 44mDelta
Deal found 12/26$1,069
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:35 amDSM - GDL
2 stops33h 15mUnited Airlines
Sat 1/35:45 amGDL - DSM
2 stops32h 48mUnited Airlines
Deal found 12/25$1,154
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:59 amDSM - GDL
2 stops11h 14mDelta
Sun 1/116:40 pmGDL - DSM
2 stops15h 58mDelta
Deal found 12/26$1,220

Find flight deals from Des Moines to Guadalajara

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$482
(Kiwi.com)

One-way from

$131
(Mytrip)

Popular in

December

Cheapest in

April

Average price

$729
Provider with most accurate pricing for Des Moines-Guadalajara Miguel Hidal flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guadalajara Miguel Hidal flights.
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From Des Moines to Guadalajara Miguel Hidal
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One-way flight from Des Moines to Guadalajara Miguel Hidal
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Des Moines

Fly to

Guadalajara

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 1/18

8:30 am-6:25 pm

1 stop9h 55m

Guadalajara Miguel Hidal

Tue 1/27

9:18 pm-3:40 pm

2 stops42h 22m

$482

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 2/10

5:51 pm-11:36 am

1 stop17h 45m

Guadalajara Miguel Hidal

Tue 2/17

2:18 pm-10:47 am

1 stop20h 29m

$508

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 2/10

5:35 am-12:48 pm

1 stop7h 13m

Guadalajara Miguel Hidal

Tue 2/17

2:15 pm-10:28 pm

1 stop8h 13m

$531

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sat 2/7

5:05 am-3:27 pm

1 stop10h 22m

Guadalajara Miguel Hidal

Sat 2/14

2:18 pm-10:47 am

1 stop20h 29m

$547

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 2/10

6:54 am-5:38 pm

2 stops10h 44m

Guadalajara Miguel Hidal

Tue 2/17

2:15 pm-10:28 pm

1 stop8h 13m

$558

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 3/2

5:24 am-12:50 pm

1 stop7h 26m

Guadalajara Miguel Hidal

Wed 3/4

6:01 am-4:27 pm

2 stops10h 26m

$568

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 1/18

3:04 pm-10:35 pm

1 stop7h 31m

Guadalajara Miguel Hidal

Tue 1/27

5:45 am-2:22 pm

1 stop8h 37m

$583

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

4:00 pm-11:59 pm

1 stop7h 59m

Guadalajara Miguel Hidal

Sat 2/7

6:00 am-5:06 pm

1 stop11h 06m

$583

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 1/26

8:30 am-4:40 am

2 stops20h 10m

$164

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

8:30 am-5:41 pm

1 stop9h 11m

$176

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 16 results
1
2

Compare providers for flights from Des Moines to Guadalajara

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guadalajara in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guadalajara flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Guadalajara flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Guadalajara flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guadalajara flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guadalajara

Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guadalajara

What is the cheapest month to book a flight from Des Moines to Guadalajara?

Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $265). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Guadalajara

Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated December 28, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,113 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,113 reviews
United Airlines
7.4
Good
9,113 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
American Airlines
7.2
Good
11,073 reviews
United Airlines
7.4
Good
9,113 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Guadalajara?

    American Airlines and Aeromexico can get you from Des Moines to Guadalajara in just under 7h 13m. Your travel time can differ by up to 10h 32m. Des Moines and Guadalajara are separated by a distance of 1557 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Guadalajara round-trip?

    According to our current data, American Airlines ($517), and United Airlines ($527) offers the cheapest pricing from Des Moines to Guadalajara. Users have found that American Airlines is 18% cheaper than the other options available to this destination.

  • Can I find deals for flights from Des Moines to Guadalajara that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guadalajara flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guadalajara?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guadalajara.

  • Can I find deals for business class flights from Des Moines to Guadalajara?

    Yes. Cheapflights offers flight deals from Des Moines to Guadalajara by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guadalajara?

    Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $265). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tlaquepaque
Zapopan

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Top 2 airlines flying from Des Moines to Guadalajara

Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$517Average$655FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$527Average$631FlexibilityNo cancel feeOn-time69%

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