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Guadalajara

$184+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Dec 7 — Dec 141
Sun 12/7
Sun 12/14
1 adult, Economy
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Cheap flight deals from Des Moines to Guadalajara

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 7, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$468
(Mytrip)

One-way from

$184
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$673
Provider with most accurate pricing for Des Moines-Guadalajara Miguel Hidal flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guadalajara Miguel Hidal flights.
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From Des Moines to Guadalajara Miguel Hidal
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One-way flight from Des Moines to Guadalajara Miguel Hidal
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Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Guadalajara

Cheapest flights from Des Moines to Guadalajara
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 7, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:32 pmDSM - GDL
1 stop25h 53mMultiple Airlines
Tue 12/28:20 pmGDL - DSM
2 stops43h 11mMultiple Airlines
Deal found 11/4$483
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:28 pmDSM - GDL
1 stop22h 13mMultiple Airlines
Mon 12/229:53 pmGDL - DSM
2 stops40h 17mMultiple Airlines
Deal found 11/3$544
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:15 amDSM - GDL
1 stop14h 20mUnited Airlines
Mon 12/158:00 amGDL - DSM
1 stop6h 12mUnited Airlines
Deal found 11/3$546
This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:58 pmDSM - GDL
2 stops17h 19mFrontier
Mon 12/227:04 amGDL - DSM
2 stops27h 15mFrontier
Deal found 11/3$573
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:28 pmDSM - GDL
1 stop25h 07mMultiple Airlines
Thu 1/16:10 amGDL - DSM
2 stops37h 34mMultiple Airlines
Deal found 11/3$584
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - GDL
2 stops32h 35mMultiple Airlines
Mon 12/159:35 amGDL - DSM
1 stop9h 03mMultiple Airlines
Deal found 11/3$585
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:29 pmDSM - GDL
2 stops24h 06mMultiple Airlines
Sat 12/278:02 amGDL - DSM
1 stop11h 42mMultiple Airlines
Deal found 11/5$595
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1011:26 amDSM - GDL
2 stops11h 09mUnited Airlines
Tue 12/25:45 amGDL - DSM
2 stops10h 27mUnited Airlines
Deal found 11/4$620
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:39 pmDSM - GDL
1 stop19h 44mAmerican Airlines
Tue 12/24:10 pmGDL - DSM
1 stop7h 01mAmerican Airlines
Deal found 11/4$628
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:54 pmDSM - GDL
1 stop24h 41mMultiple Airlines
Fri 1/28:00 amGDL - DSM
2 stops35h 44mMultiple Airlines
Deal found 11/4$639

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 7, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Des Moines

Fly to

Guadalajara

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

8:30 am-8:35 pm

1 stop12h 05m

Guadalajara Miguel Hidal

Sat 2/7

6:08 am-3:03 pm

2 stops32h 55m

$460

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 11/10

2:32 pm-4:25 pm

1 stop25h 53m

Guadalajara Miguel Hidal

Tue 12/2

8:20 pm-3:31 pm

2 stops43h 11m

$483

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

8:30 am-5:41 pm

1 stop9h 11m

Guadalajara Miguel Hidal

Sun 2/8

9:35 pm-3:40 pm

2 stops18h 05m

$492

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 1/22

8:30 am-6:25 pm

1 stop9h 55m

Guadalajara Miguel Hidal

Sat 2/7

9:35 am-3:40 pm

1 stop30h 05m

$515

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 12/8

7:28 pm-5:41 pm

1 stop22h 13m

Guadalajara Miguel Hidal

Mon 12/22

9:53 pm-2:10 pm

2 stops40h 17m

$544

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/16

4:00 pm-11:59 pm

1 stop7h 59m

Guadalajara Miguel Hidal

Mon 1/19

4:44 pm-11:23 pm

1 stop6h 39m

$571

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 12/8

7:58 pm-1:17 pm

2 stops17h 19m

Guadalajara Miguel Hidal

Mon 12/22

7:04 am-10:19 am

2 stops27h 15m

$573

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 12/12

7:28 pm-8:35 pm

1 stop25h 07m

Guadalajara Miguel Hidal

Thu 1/1

6:10 am-7:44 pm

2 stops37h 34m

$584

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 12/11

2:56 pm-11:31 pm

2 stops32h 35m

Guadalajara Miguel Hidal

Mon 12/15

9:35 am-6:38 pm

1 stop9h 03m

$585

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 1/19

8:30 am-6:25 pm

1 stop9h 55m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 15 results
1
2

Compare providers for flights from Des Moines to Guadalajara

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guadalajara in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guadalajara flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Guadalajara flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Guadalajara flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guadalajara flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guadalajara

Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guadalajara

What is the cheapest month to book a flight from Des Moines to Guadalajara?

Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $291). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Guadalajara?

Reviews of airlines servicing Guadalajara

Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated November 7, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,007 reviews
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.2
Good
11,040 reviews
United Airlines
7.4
Good
9,007 reviews

Food

6.6

Crew

8.1

Comfort

7.3

Entertainment

7.1

Overall

7.4

Boarding

7.7

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guadalajara round-trip?

    According to our current data, American Airlines ($518), and United Airlines ($521) offers the cheapest pricing from Des Moines to Guadalajara. Users have found that American Airlines is 17% cheaper than the other options available to this destination.

  • Can I find deals for flights from Des Moines to Guadalajara that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guadalajara flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guadalajara?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guadalajara.

  • Can I find deals for business class flights from Des Moines to Guadalajara?

    Yes. Cheapflights offers flight deals from Des Moines to Guadalajara by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guadalajara?

    Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $291). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tlaquepaque
Zapopan

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Top 2 airlines flying from Des Moines to Guadalajara

Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$518Average$645FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$521Average$691FlexibilityNo cancel feeOn-time69%

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