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Guadalajara

$290+ Cheap flights from Des Moines (DSM) to Guadalajara (GDL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GDL
Nov 22 — Nov 291
Sat 11/22
Sat 11/29
1 adult, Economy
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Cheap flight deals from Des Moines to Guadalajara

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Guadalajara (GDL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$430
(Kiwi.com)

One-way from

$290
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$591
Provider with most accurate pricing for Des Moines-Guadalajara Miguel Hidal flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Guadalajara Miguel Hidal flights.
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From Des Moines to Guadalajara Miguel Hidal
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One-way flight from Des Moines to Guadalajara Miguel Hidal
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Highest demand for flights based on searches. 10% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Des Moines to Guadalajara

Cheapest flights from Des Moines to Guadalajara
Explore the most affordable flight options available from Des Moines to Guadalajara. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:58 pmDSM - GDL
2 stops35h 32mMultiple Airlines
Fri 12/1210:25 amGDL - DSM
1 stop8h 13mMultiple Airlines
Deal found 10/21$430
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:56 pmDSM - GDL
2 stops22h 25mMultiple Airlines
Thu 12/1112:29 pmGDL - DSM
1 stop30h 09mMultiple Airlines
Deal found 10/22$474
This Mytrip deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:56 pmDSM - GDL
2 stops22h 25mMultiple Airlines
Sun 12/146:31 pmGDL - DSM
2 stops26h 38mMultiple Airlines
Deal found 10/22$509
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:38 pmDSM - GDL
1 stop8h 12mAmerican Airlines
Thu 12/115:44 amGDL - DSM
1 stop10h 56mAmerican Airlines
Deal found 10/22$565
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/239:01 amDSM - GDL
2 stops13h 34mUnited Airlines
Wed 11/263:22 pmGDL - DSM
1 stop6h 58mUnited Airlines
Deal found 10/21$576
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/711:29 amDSM - GDL
1 stop12h 21mAmerican Airlines
Sun 12/144:09 pmGDL - DSM
1 stop6h 39mAmerican Airlines
Deal found 10/22$582
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:53 pmDSM - GDL
1 stop5h 57mUnited Airlines
Mon 12/151:35 pmGDL - DSM
2 stops10h 09mUnited Airlines
Deal found 10/20$583

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Des Moines

Fly to

Guadalajara

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 12/5

7:58 pm-7:30 am

2 stops35h 32m

Guadalajara Miguel Hidal

Fri 12/12

10:25 am-6:38 pm

1 stop8h 13m

$430

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 12/7

8:30 am-8:35 pm

1 stop12h 05m

Guadalajara Miguel Hidal

Sun 12/14

6:31 pm-9:09 pm

2 stops26h 38m

$516

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 12/4

2:56 pm-7:20 am

3 stops40h 24m

Guadalajara Miguel Hidal

Thu 12/11

11:03 pm-12:55 pm

1 stop13h 52m

$519

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 3/9

5:15 pm-2:13 pm

2 stops21h 58m

Guadalajara Miguel Hidal

Wed 3/11

6:45 pm-3:35 pm

2 stops19h 50m

$566

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 11/23

5:00 am-11:30 am

1 stop6h 30m

Guadalajara Miguel Hidal

Wed 11/26

6:00 am-2:51 pm

1 stop8h 51m

$576

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 11/23

1:05 pm-10:35 pm

2 stops9h 30m

Guadalajara Miguel Hidal

Wed 11/26

5:45 am-4:12 pm

2 stops10h 27m

$581

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 12/7

11:29 am-11:50 pm

1 stop12h 21m

Guadalajara Miguel Hidal

Sun 12/14

4:09 pm-10:48 pm

1 stop6h 39m

$582

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 12/2

2:53 pm-8:50 pm

1 stop5h 57m

Guadalajara Miguel Hidal

Mon 12/15

1:35 pm-11:44 pm

2 stops10h 09m

$583

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 12/21

8:30 am-8:35 pm

1 stop12h 05m

$290

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 12/7

3:38 pm-11:50 pm

1 stop8h 12m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Guadalajara

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Guadalajara in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Guadalajara flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Guadalajara flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Guadalajara flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Guadalajara flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Guadalajara flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Guadalajara

Have a flexible travel schedule? Discover the best time to fly to Guadalajara from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Guadalajara

What is the cheapest month to book a flight from Des Moines to Guadalajara?

Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $291). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Guadalajara?

Reviews of airlines servicing Guadalajara

Get insights into the airlines that provide service to Guadalajara. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guadalajara. Reviews last updated October 23, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Guadalajara to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
8,995 reviews
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
American Airlines
7.2
Good
11,032 reviews
United Airlines
7.4
Good
8,995 reviews

Comfort

7.3

Entertainment

7.1

Crew

8.1

Boarding

7.7

Food

6.6

Overall

7.4

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Guadalajara. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Guadalajara round-trip?

    According to our current data, American Airlines ($517), and United Airlines ($521) offers the cheapest pricing from Des Moines to Guadalajara. Users have found that American Airlines is 17% cheaper than the other options available to this destination.

  • Can I find deals for flights from Des Moines to Guadalajara that include hotel bookings?

    Yes. In addition to deals on Des Moines to Guadalajara flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Guadalajara?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Guadalajara.

  • Can I find deals for business class flights from Des Moines to Guadalajara?

    Yes. Cheapflights offers flight deals from Des Moines to Guadalajara by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Guadalajara?

    Currently, March is the cheapest month in which you can book a flight from Des Moines to Guadalajara (average of $291). Flying from Des Moines to Guadalajara in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tlaquepaque
Zapopan

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Top 2 airlines flying from Des Moines to Guadalajara

Discover the top 2 airlines that operate flights from Des Moines to Guadalajara. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$517Average$623FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$521Average$691FlexibilityNo cancel feeOn-time69%

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