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Greenville

$294+ Cheap flights from Panama to Greenville (GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — GSP
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Panama to Greenville

Keep the following information in mind while searching for Panama to Greenville flight deals. Data was last updated July 31, 2025.

Round-trip from

$501
(American Airlines)

One-way from

$294
(American Airlines)
From Panama to Greenville
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One-way flight from Panama to Greenville
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Find flight deals from Panama to Greenville

Cheapest flights from Panama to Greenville
Explore the most affordable flight options available from Panama to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/53:31 pmPTY - GSP
1 stop7h 25mAmerican Airlines
Wed 1/145:38 amGSP - PTY
1 stop7h 32mAmerican Airlines
Deal found 7/29$501
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:55 amPTY - GSP
1 stop13h 05mUnited Airlines
Sat 9/67:00 amGSP - PTY
1 stop12h 37mUnited Airlines
Deal found 7/31$576
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:20 amPTY - GSP
2 stops14h 26mMultiple Airlines
Fri 9/197:26 pmGSP - PTY
3 stops46h 04mMultiple Airlines
Deal found 7/29$881

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama to Greenville that are best for you.

Fly from

Panama

Fly to

Greenville

Route

Depart

Return

Price

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Fri 9/5

3:31 pm-11:56 pm

1 stop7h 25m

Greenville

Wed 1/14

5:38 am-1:10 pm

1 stop7h 32m

$501

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Tue 8/12

7:55 am-10:00 pm

1 stop13h 05m

Greenville

Sat 9/6

7:00 am-6:37 pm

1 stop12h 37m

$576

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 9/11

3:20 am-6:46 pm

2 stops14h 26m

Greenville

Fri 9/19

7:26 pm-4:30 pm

3 stops46h 04m

$881

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Fri 9/26

3:31 pm-11:56 pm

1 stop7h 25m

$294

Panama CityGreenville

PTY - GSP

PTYGSP

Panama City Tocumen Intl

Thu 9/25

3:20 am-6:46 pm

2 stops14h 26m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Panama to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Greenville

What is the cheapest month to book a flight from Panama to Greenville?

Currently, January is the cheapest month in which you can book a flight from Panama to Greenville (average of $329). Flying from Panama to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated July 31, 2025.
See what other customers who have flown with United Airlines and American Airlines from Panama to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
United Airlines
7.4
Good
8,900 reviews
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,900 reviews

Comfort

7.3

Overall

7.4

Boarding

7.7

Food

6.6

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Thomas,Apr 2025

TPE - SFO

The boarding experience was okay. The dietary food choices were limited, the midway snacks were hard and dry. The seat was uncomfortable - stiff seat cushion, seat back kept springing back to the upright position, narrow seat width. Love the app and the ability to track my luggage. Flight crew was efficient.

Related info for your journey

Find useful and relevant information for your journey from Panama to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Panama?

    For a flight from Panama to Greenville, you will be flying into Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • Can I find deals for flights from Panama to Greenville that include hotel bookings?

    Yes. In addition to deals on Panama to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Greenville.

  • Can I find deals for business class flights from Panama to Greenville?

    Yes. Cheapflights offers flight deals from Panama to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Panama to Greenville (average of $329). Flying from Panama to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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