$270+ Cheap flights from Panama to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Find cheap flights from Panama to South Carolina with Cheapflights
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Cheapest flights from Panama to South CarolinaExplore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Panama to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:30 am
PTY
- CLT
2 stops10h 42m
Multiple Airlines
Fri 7/316:48 pm
CLT
- PTY
1 stop14h 18m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:55 pm
PTY
- CLT
2 stops22h 17m
Multiple Airlines
Tue 8/46:48 pm
CLT
- PTY
1 stop14h 42m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$521
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:21 pm
PTY
- CLT
1 stop8h 36m
Delta
Mon 9/145:30 am
CLT
- PTY
1 stop8h 26m
Delta
Deal found 6/4![Delta logo]()
$551
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:25 am
PTY
- CLT
2 stops15h 42m
Multiple Airlines
Mon 8/36:48 pm
CLT
- PTY
1 stop14h 18m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:16 pm
PTY
- CLT
1 stop6h 58m
American Airlines
Mon 9/141:30 pm
CLT
- PTY
1 stop23h 54m
American Airlines
Deal found 6/6![American Airlines logo]()
$570
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:30 pm
PTY
- CLT
1 stop17h 10m
Delta
Mon 11/306:45 am
CLT
- PTY
1 stop7h 20m
Delta
Deal found 6/8![Delta logo]()
$583
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:24 pm
PTY
- CHS
1 stop9h 02m
Delta
Tue 7/285:10 am
CHS
- PTY
1 stop8h 55m
Delta
Deal found 6/7![Delta logo]()
$591
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/252:27 pm
PTY
- CLT
1 stop28h 47m
Delta
Mon 8/37:54 pm
CLT
- PTY
1 stop18h 01m
Delta
Deal found 6/5![Delta logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/241:14 pm
PTY
- CHS
2 stops21h 26m
American Airlines
Tue 7/286:00 am
CHS
- PTY
1 stop7h 14m
American Airlines
Deal found 6/7![American Airlines logo]()
$594
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:16 pm
PTY
- GSP
2 stops20h 47m
American Airlines
Sun 10/46:23 pm
GSP
- PTY
2 stops20h 37m
American Airlines
Deal found 6/5![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/263:35 pm
PTY
- CLT
1 stop18h 01m
American Airlines
Thu 11/58:19 pm
CLT
- PTY
1 stop17h 17m
American Airlines
Deal found 6/7![American Airlines logo]()
$602
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:55 pm
PTY
- CHS
1 stop8h 56m
United Airlines
Tue 7/2811:13 am
CHS
- PTY
1 stop17h 51m
United Airlines
Deal found 6/4![United Airlines logo]()
$609
Best flights from Panama to South CarolinaDiscover carefully curated flight deals from Panama to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Panama to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/102:21 pm
PTY
- CLT
1 stop8h 36m
Delta
Mon 9/145:30 am
CLT
- PTY
1 stop8h 26m
Delta
Deal found 6/4![Delta logo]()
$551
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:16 pm
PTY
- GSP
2 stops20h 47m
American Airlines
Sun 10/46:23 pm
GSP
- PTY
2 stops20h 37m
American Airlines
Deal found 6/5![American Airlines logo]()
$597
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:55 pm
PTY
- CHS
1 stop8h 56m
United Airlines
Tue 7/2811:13 am
CHS
- PTY
1 stop17h 51m
United Airlines
Deal found 6/5![United Airlines logo]()
$609
This Faresmojo deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:21 pm
PTY
- AGS
1 stop8h 34m
JetBlue
Sat 10/175:45 am
AGS
- PTY
1 stop8h 11m
JetBlue
Deal found 6/6![JetBlue logo]()
$797
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:24 pm
PTY
- CHS
1 stop9h 02m
Delta
Tue 7/285:10 am
CHS
- PTY
1 stop8h 55m
Delta
Deal found 6/7![Delta logo]()
$591
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:43 pm
PTY
- AGS
2 stops22h 10m
American Airlines
Sat 11/146:12 pm
AGS
- PTY
2 stops19h 24m
American Airlines
Deal found 6/7![American Airlines logo]()
$654
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:30 pm
PTY
- AGS
1 stop8h 25m
Delta
Sat 11/147:00 am
AGS
- PTY
1 stop7h 05m
Delta
Deal found 6/7![Delta logo]()
$630
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:55 pm
PTY
- GSP
1 stop10h 40m
United Airlines
Tue 9/111:25 am
GSP
- PTY
1 stop9h 06m
United Airlines
Deal found 6/5![United Airlines logo]()
$705
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:14 pm
PTY
- GSP
2 stops22h 00m
American Airlines
Wed 9/21:37 pm
GSP
- PTY
2 stops24h 02m
American Airlines
Deal found 6/8![American Airlines logo]()
$659
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:30 pm
PTY
- GSP
1 stop29h 28m
United Airlines
Mon 8/178:29 pm
GSP
- PTY
1 stop8h 35m
United Airlines
Deal found 6/8![United Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/233:30 pm
PTY
- CLT
1 stop8h 23m
Delta
Tue 12/15:30 am
CLT
- PTY
1 stop8h 35m
Delta
Deal found 6/8![Delta logo]()
$657
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/281:15 pm
PTY
- GSP
1 stop9h 44m
American Airlines
Sat 9/265:14 pm
GSP
- PTY
2 stops20h 02m
American Airlines
Deal found 6/4![American Airlines logo]()
$689
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2210:00 am
PTY
- CLT
1 stop8h 48m
United Airlines
Tue 12/16:00 am
CLT
- PTY
2 stops14h 02m
United Airlines
Deal found 6/8![United Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:00 am
PTY
- CLT
2 stops13h 34m
United Airlines
Thu 12/36:00 am
CLT
- PTY
2 stops14h 02m
United Airlines
Deal found 6/8![United Airlines logo]()
$707
This WestJet deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:20 am
PTY
- AGS
2 stops30h 36m
WestJet
Sat 11/1411:35 am
AGS
- PTY
2 stops20h 45m
WestJet
Deal found 6/4![WestJet logo]()
$1,968
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:30 pm
PTY
- CLT
2 stops21h 20m
United Airlines
Tue 7/288:05 am
CLT
- PTY
2 stops11h 32m
United Airlines
Deal found 6/6![United Airlines logo]()
$707
This oojo deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:02 pm
PTY
- AGS
2 stops18h 14m
Multiple Airlines
Sat 10/175:45 pm
AGS
- PTY
2 stops20h 36m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$2,171
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/282:20 pm
PTY
- AGS
1 stop8h 38m
Delta
Mon 9/77:00 am
AGS
- PTY
1 stop6h 55m
Delta
Deal found 6/5![Delta logo]()
$818
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:55 pm
PTY
- CAE
2 stops21h 21m
United Airlines
Tue 7/2811:19 am
CAE
- PTY
1 stop17h 45m
United Airlines
Deal found 6/5![United Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:55 am
PTY
- CLT
1 stop13h 04m
United Airlines
Sun 8/211:20 am
CLT
- PTY
1 stop17h 44m
United Airlines
Deal found 6/5![United Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:55 am
PTY
- CAE
2 stops25h 01m
United Airlines
Fri 7/247:45 pm
CAE
- PTY
2 stops23h 52m
United Airlines
Deal found 6/7![United Airlines logo]()
$716
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:45 am
PTY
- CLT
2 stops22h 59m
United Airlines
Sat 8/18:05 am
CLT
- PTY
2 stops20h 59m
United Airlines
Deal found 6/4![United Airlines logo]()
$718
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/243:30 pm
PTY
- CLT
2 stops17h 13m
United Airlines
Tue 7/282:35 pm
CLT
- PTY
1 stop14h 29m
United Airlines
Deal found 6/4![United Airlines logo]()
$721
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:16 pm
PTY
- AGS
3 stops19h 31m
American Airlines
Tue 9/297:25 pm
AGS
- PTY
3 stops17h 59m
American Airlines
Deal found 6/5![American Airlines logo]()
$2,489
Last-minute flights from Panama to South CarolinaDiscover last-minute flight deals from Panama to South Carolina. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to South Carolina. Data last updated June 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/281:15 pm
PTY
- GSP
2 stops20h 35m
American Airlines
Sat 9/267:41 pm
GSP
- PTY
2 stops17h 35m
American Airlines
Deal found 6/7![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:14 pm
PTY
- GSP
2 stops22h 00m
American Airlines
Wed 9/26:40 pm
GSP
- PTY
1 stop18h 59m
American Airlines
Deal found 6/8![American Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:30 am
PTY
- CLT
2 stops10h 42m
Multiple Airlines
Fri 7/316:48 pm
CLT
- PTY
1 stop14h 18m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$495
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:24 pm
PTY
- GSP
1 stop8h 30m
Delta
Tue 7/285:44 am
GSP
- PTY
1 stop8h 21m
Delta
Deal found 6/4![Delta logo]()
$648
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:03 pm
PTY
- CLT
1 stop8h 04m
Multiple Airlines
Tue 7/286:48 pm
CLT
- PTY
1 stop14h 18m
Multiple Airlines
Deal found 6/4![Multiple Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/242:24 pm
PTY
- CHS
1 stop9h 02m
Delta
Tue 7/285:10 am
CHS
- PTY
1 stop8h 55m
Delta
Deal found 6/7![Delta logo]()
$591
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/241:14 pm
PTY
- CHS
2 stops21h 26m
American Airlines
Tue 7/286:00 am
CHS
- PTY
1 stop7h 14m
American Airlines
Deal found 6/7![American Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:55 pm
PTY
- CHS
1 stop8h 56m
United Airlines
Tue 7/2811:13 am
CHS
- PTY
1 stop17h 51m
United Airlines
Deal found 6/4![United Airlines logo]()
$609
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:25 am
PTY
- CLT
2 stops15h 42m
Multiple Airlines
Mon 8/36:48 pm
CLT
- PTY
1 stop14h 18m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$558
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/252:27 pm
PTY
- CLT
1 stop28h 47m
Delta
Mon 8/37:54 pm
CLT
- PTY
1 stop18h 01m
Delta
Deal found 6/5![Delta logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:55 pm
PTY
- CLT
2 stops22h 17m
Multiple Airlines
Tue 8/46:48 pm
CLT
- PTY
1 stop14h 42m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$521
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:55 am
PTY
- CLT
2 stops12h 34m
United Airlines
Tue 8/41:06 pm
CLT
- PTY
2 stops15h 58m
United Airlines
Deal found 6/8![United Airlines logo]()
$686
One-way flights from Panama to South CarolinaSearch for one-way flight options from Panama to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Panama to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Trip.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:25 am
PTY
- CLT
2 stops11h 47m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am
PTY
- CLT
3 stops33h 35m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:16 pm
PTY
- GSP
1 stop7h 39m
American Airlines
Deal found 6/5![American Airlines logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:45 am
PTY
- CHS
2 stops23h 22m
United Airlines
Deal found 6/4![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:24 pm
PTY
- CHS
1 stop9h 02m
Delta
Deal found 6/4![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/301:16 pm
PTY
- CLT
1 stop19h 45m
American Airlines
Deal found 6/5![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:24 pm
PTY
- CHS
1 stop9h 02m
Delta
Deal found 6/6![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:55 pm
PTY
- CHS
2 stops21h 53m
United Airlines
Deal found 6/4![United Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:00 am
PTY
- CHS
1 stop11h 15m
United Airlines
Deal found 6/6![United Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:30 am
PTY
- CLT
3 stops15h 05m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:45 am
PTY
- CHS
1 stop22h 06m
United Airlines
Deal found 6/4![United Airlines logo]()
$337
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:30 pm
PTY
- CLT
1 stop8h 23m
Delta
Deal found 6/5![Delta logo]()
$341
Find flight deals from Panama to South Carolina
Keep the following information in mind while searching for Panama to South Carolina flight deals. Data was last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $495 (Kiwi.com) |
One-way from | $270 (Trip.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Panama to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Thu 9/10
2:21 pm-11:57 pm
1 stop8h 36m
Charlotte Douglas
Mon 9/14
5:30 am-12:56 pm
1 stop8h 26m
$551
Panama CityCharleston
PTY - CHS
PTYCHS
Panama City Tocumen Intl
Fri 7/24
2:24 pm-12:26 am
1 stop9h 02m
Charleston
Tue 7/28
5:10 am-1:05 pm
1 stop8h 55m
$591
Panama CityGreenville
PTY - GSP
PTYGSP
Panama City Tocumen Intl
Wed 9/30
1:16 pm-11:03 am
2 stops20h 47m
Greenville
Sun 10/4
6:23 pm-2:00 pm
2 stops20h 37m
$597
Panama CityCharleston
PTY - CHS
PTYCHS
Panama City Tocumen Intl
Fri 7/24
10:55 pm-8:51 am
1 stop8h 56m
Charleston
Tue 7/28
11:13 am-4:04 am
1 stop17h 51m
$609
Quickest round-trip
Panama CityAugusta
PTY - AGS
PTYAGS
Panama City Tocumen Intl
Wed 11/11
3:30 pm-11:55 pm
1 stop8h 25m
Augusta Bush Field
Sat 11/14
7:00 am-2:05 pm
1 stop7h 05m
$630
Panama CityAugusta
PTY - AGS
PTYAGS
Panama City Tocumen Intl
Wed 11/11
2:43 pm-12:53 pm
2 stops22h 10m
Augusta Bush Field
Sat 11/14
6:12 pm-1:36 pm
2 stops19h 24m
$654
Panama CityCharlotte
PTY - CLT
PTYCLT
Panama City Tocumen Intl
Mon 11/23
3:30 pm-11:53 pm
1 stop8h 23m
Charlotte Douglas
Tue 12/1
5:30 am-2:05 pm
1 stop8h 35m
$657
Panama CityGreenville
PTY - GSP
PTYGSP
Panama City Tocumen Intl
Wed 7/15
1:14 pm-12:14 pm
2 stops22h 00m
Greenville
Wed 9/2
1:37 pm-12:39 pm
2 stops24h 02m
$659
Panama CityGreenville
PTY - GSP
PTYGSP
Panama City Tocumen Intl
Sun 6/28
1:15 pm-11:59 pm
1 stop9h 44m
Greenville
Sat 9/26
5:14 pm-12:16 pm
2 stops20h 02m
$689
Panama CityGreenville
PTY - GSP
PTYGSP
Panama City Tocumen Intl
Sat 8/29
10:55 pm-10:35 am
1 stop10h 40m
Greenville
Tue 9/1
11:25 am-7:31 pm
1 stop9h 06m
$705
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Panama to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama with our price prediction graph.
PTY-CLT
PTY-GSP
PTY-CHS
PTY-AGS
PTY-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to South Carolina
PA0-USSC
PTY-CLT
PTY-GSP
PTY-CHS
PTY-AGS
What is the cheapest month to book a flight from Panama to South Carolina?
Currently, December is the cheapest month in which you can book a flight from Panama to South Carolina (average of $148). Flying from Panama to South Carolina in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 9, 2026.
Read through reviews of airlines operating flights from Panama to South Carolina, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Overall
7.1
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentBeatriz,May 2026
HEL - DFW
Entertainment
6.9
Boarding
7.5
Comfort
7.2
Overall
7.1
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentBeatriz,May 2026
HEL - DFW
Related info for your journey
Find useful and relevant information for your journey from Panama to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to South Carolina by cabin class
Find flights from Panama to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and South Carolina flights
Browse other Panama and South Carolina flight options. Last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Panama after your stay in South Carolina
Panama to South Carolina flights
Consider these flights traveling from Panama to South Carolina.
Top airline flying from Panama to South Carolina
Discover the top airline that operate flights from Panama to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$397 | Average$577 | FlexibilityNo cancel fee | On-time71% |