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$257+ Cheap flights from Louisville to Greenville (SDF - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GSP
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Louisville to Greenville

Cheapest flights from Louisville to Greenville
Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:35 amSDF - GSP
1 stop4h 39mDelta
Sat 12/137:25 amGSP - SDF
1 stop6h 58mDelta
Deal found 11/6$257
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:28 pmSDF - GSP
2 stops6h 29mAmerican Airlines
Sat 12/136:00 amGSP - SDF
1 stop6h 30mAmerican Airlines
Deal found 11/6$262
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:16 pmSDF - GSP
1 stop4h 17mDelta
Thu 12/115:35 amGSP - SDF
1 stop4h 15mDelta
Deal found 11/6$277
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:16 pmSDF - GSP
1 stop5h 24mDelta
Fri 12/196:45 amGSP - SDF
1 stop3h 05mDelta
Deal found 11/4$302
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:53 amSDF - GSP
1 stop6h 13mAmerican Airlines
Sat 12/275:39 amGSP - SDF
1 stop5h 15mAmerican Airlines
Deal found 11/5$326
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:24 pmSDF - GSP
1 stop4h 34mAmerican Airlines
Fri 12/265:39 amGSP - SDF
1 stop5h 09mAmerican Airlines
Deal found 11/6$327
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:08 amSDF - GSP
2 stops5h 29mAmerican Airlines
Thu 12/116:39 amGSP - SDF
1 stop4h 38mAmerican Airlines
Deal found 11/6$343
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:05 amSDF - GSP
1 stop3h 22mDelta
Mon 11/241:58 pmGSP - SDF
1 stop5h 14mDelta
Deal found 11/5$344
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:45 amSDF - GSP
2 stops7h 55mSouthwest
Fri 12/198:20 pmGSP - SDF
1 stop4h 10mSouthwest
Deal found 11/4$366
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:45 amSDF - GSP
2 stops7h 55mSouthwest
Thu 12/1110:35 amGSP - SDF
2 stops12h 30mSouthwest
Deal found 11/6$377
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:48 pmSDF - GSP
2 stops24h 35mMultiple Airlines
Mon 11/249:53 pmGSP - SDF
1 stop20h 00mMultiple Airlines
Deal found 11/5$394
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:10 amSDF - GSP
2 stops6h 05mSouthwest
Sat 12/138:10 amGSP - SDF
2 stops8h 00mSouthwest
Deal found 11/6$399

Cheap flight deals from Louisville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$257
(Delta)

Popular in

October

Cheapest in

September

Average price

$536
Provider with most accurate pricing for Louisville Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Greenville flights.
Search Deals
From Louisville Intl to Greenville
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Louisville

Fly to

Greenville

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 12/6

8:35 am-1:14 pm

1 stop4h 39m

Greenville

Sat 12/13

7:25 am-2:23 pm

1 stop6h 58m

$257

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 3/24

6:00 am-9:27 am

1 stop3h 27m

Greenville

Wed 3/25

7:45 am-1:50 pm

1 stop6h 05m

$257

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 12/6

5:28 pm-11:57 pm

2 stops6h 29m

Greenville

Sat 12/13

6:00 am-12:30 pm

1 stop6h 30m

$262

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 12/8

6:16 pm-10:33 pm

1 stop4h 17m

Greenville

Thu 12/11

5:35 am-9:50 am

1 stop4h 15m

$277

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 12/15

6:16 pm-11:40 pm

1 stop5h 24m

Greenville

Fri 12/19

6:45 am-9:50 am

1 stop3h 05m

$302

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 3/24

1:43 pm-11:59 pm

2 stops10h 16m

Greenville

Wed 3/25

10:00 am-2:47 pm

1 stop4h 47m

$322

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 12/20

7:53 am-2:06 pm

1 stop6h 13m

Greenville

Sat 12/27

5:39 am-10:54 am

1 stop5h 15m

$326

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 12/22

7:24 pm-11:58 pm

1 stop4h 34m

Greenville

Fri 12/26

5:39 am-10:48 am

1 stop5h 09m

$327

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 3/9

2:59 pm-6:49 pm

1 stop3h 50m

Greenville

Thu 3/12

7:55 pm-11:56 pm

1 stop4h 01m

$327

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 12/8

6:08 am-11:37 am

2 stops5h 29m

Greenville

Thu 12/11

6:39 am-11:17 am

1 stop4h 38m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 12 results
1
2

Compare providers for flights from Louisville to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Greenville

What is the cheapest month to book a flight from Louisville to Greenville?

Currently, September is the cheapest month in which you can book a flight from Louisville to Greenville (average of $128). Flying from Louisville to Greenville in January is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 6, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Louisville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Greenville?

    For as low as $257, Delta can have you in Greenville from Louisville in 4h 39m. The distance between Louisville and Greenville is about 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Louisville to Greenville round-trip?

    Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $190. Another option worth looking into is Delta, starting at $196 round trip. American Airlines is 52% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Louisville to Greenville that include hotel bookings?

    Yes. In addition to deals on Louisville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Greenville.

  • Can I find deals for business class flights from Louisville to Greenville?

    Yes. Cheapflights offers flight deals from Louisville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Greenville?

    Currently, September is the cheapest month in which you can book a flight from Louisville to Greenville (average of $128). Flying from Louisville to Greenville in January is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 2 airlines flying from Louisville to Greenville

Discover the top 2 airlines that operate flights from Louisville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$190Average$291FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$306FlexibilityNo cancel feeOn-timeN/A

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