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$217+ Cheap flights from Louisville to Greenville (SDF - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GSP
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Louisville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$217
(Kiwi.com)

Popular in

October

Cheapest in

June

Average price

$296
From Louisville Intl to Greenville
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($86 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
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Find flight deals from Louisville to Greenville

Cheapest flights from Louisville to Greenville
Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amSDF - GSP
1 stop13h 23mMultiple Airlines
Thu 12/1111:34 amGSP - SDF
1 stop28h 49mMultiple Airlines
Deal found 9/13$217
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:08 amSDF - GSP
2 stops5h 29mAmerican Airlines
Thu 12/114:29 pmGSP - SDF
1 stop5h 19mAmerican Airlines
Deal found 9/13$262
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/41:58 pmSDF - GSP
1 stop7h 20mUnited Airlines
Sat 10/113:55 pmGSP - SDF
1 stop6h 35mUnited Airlines
Deal found 9/12$308
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:45 amSDF - GSP
2 stops9h 20mSouthwest
Thu 12/1110:35 amGSP - SDF
2 stops12h 30mSouthwest
Deal found 9/13$313
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:10 amSDF - GSP
1 stop5h 19mDelta
Sun 10/55:30 amGSP - SDF
1 stop3h 19mDelta
Deal found 9/13$387
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/128:15 pmSDF - GSP
1 stop3h 40mDelta
Sun 10/195:30 amGSP - SDF
1 stop3h 24mDelta
Deal found 9/14$399
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/295:18 pmSDF - GSP
1 stop5h 40mAmerican Airlines
Fri 10/37:38 pmGSP - SDF
1 stop3h 37mAmerican Airlines
Deal found 9/14$407
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/287:33 pmSDF - GSP
1 stop4h 19mDelta
Thu 10/25:30 amGSP - SDF
1 stop4h 30mDelta
Deal found 9/13$415
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/128:52 pmSDF - GSP
1 stop22h 31mMultiple Airlines
Sun 10/193:42 pmGSP - SDF
2 stops19h 10mMultiple Airlines
Deal found 9/14$438
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:14 amSDF - GSP
1 stop8h 32mMultiple Airlines
Sun 9/2811:18 amGSP - SDF
1 stop22h 01mMultiple Airlines
Deal found 9/13$448

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Louisville

Fly to

Greenville

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 10/4

1:58 pm-9:18 pm

1 stop7h 20m

Greenville

Sat 10/11

3:55 pm-10:30 pm

1 stop6h 35m

$308

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 12/8

6:45 am-4:05 pm

2 stops9h 20m

Greenville

Thu 12/11

10:35 am-11:05 pm

2 stops12h 30m

$313

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

8:10 am-1:29 pm

1 stop5h 19m

Greenville

Sun 10/5

5:30 am-8:49 am

1 stop3h 19m

$387

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 10/12

8:15 pm-11:55 pm

1 stop3h 40m

Greenville

Sun 10/19

5:30 am-8:54 am

1 stop3h 24m

$399

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 9/29

5:18 pm-10:58 pm

1 stop5h 40m

Greenville

Fri 10/3

7:38 pm-11:15 pm

1 stop3h 37m

$407

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 9/28

7:33 pm-11:52 pm

1 stop4h 19m

Greenville

Thu 10/2

5:30 am-10:00 am

1 stop4h 30m

$415

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 10/12

8:52 pm-7:23 pm

1 stop22h 31m

Greenville

Sun 10/19

3:42 pm-10:52 am

2 stops19h 10m

$438

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 9/26

10:14 am-6:46 pm

1 stop8h 32m

Greenville

Sun 9/28

11:18 am-9:19 am

1 stop22h 01m

$448

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 9/22

4:20 pm-9:00 pm

1 stop4h 40m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Louisville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Greenville

What is the cheapest month to book a flight from Louisville to Greenville?

Currently, August is the cheapest month in which you can book a flight from Louisville to Greenville (average of $322). Flying from Louisville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Louisville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Greenville?

    For as low as $387, United Airlines can have you in Greenville from Louisville in 5h 19m. The distance between Louisville and Greenville is about 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Louisville to Greenville round-trip?

    Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $190. Another option worth looking into is Delta, starting at $196 round trip. American Airlines is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Louisville to Greenville that include hotel bookings?

    Yes. In addition to deals on Louisville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Greenville.

  • Can I find deals for business class flights from Louisville to Greenville?

    Yes. Cheapflights offers flight deals from Louisville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Greenville?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Greenville (average of $322). Flying from Louisville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 2 airlines flying from Louisville to Greenville

Discover the top 2 airlines that operate flights from Louisville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$190Average$486FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$306FlexibilityNo cancel feeOn-timeN/A

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