HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Greenville

$88+ Cheap flights from Louisville to Greenville (SDF - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GSP
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Louisville to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Louisville to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 16, 2025.

Round-trip from

$245
(Delta)

One-way from

$88
(American Airlines)

Popular in

February

Cheapest in

June

Average price

$306
From Louisville Intl to Greenville
Search Deals
One-way flight from Louisville Intl to Greenville
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Louisville to Greenville

Cheapest flights from Louisville to Greenville
Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/118:10 amSDF - GSP
1 stop5h 18mDelta
Mon 9/155:30 amGSP - SDF
1 stop4h 30mDelta
Deal found 8/15$245
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/162:33 pmSDF - GSP
1 stop6h 59mDelta
Mon 10/207:41 pmGSP - SDF
1 stop4h 18mDelta
Deal found 8/15$299
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:20 pmSDF - GSP
1 stop4h 40mSouthwest
Mon 9/297:40 amGSP - SDF
1 stop4h 50mSouthwest
Deal found 8/14$302
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:33 pmSDF - GSP
1 stop4h 19mDelta
Sat 9/275:30 amGSP - SDF
1 stop6h 13mDelta
Deal found 8/14$348
This Southwest deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/161:20 pmSDF - GSP
1 stop6h 05mSouthwest
Mon 10/201:50 pmGSP - SDF
2 stops9h 50mSouthwest
Deal found 8/15$362
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/117:20 amSDF - GSP
2 stops6h 56mUnited Airlines
Mon 9/155:34 pmGSP - SDF
1 stop4h 50mUnited Airlines
Deal found 8/15$407
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:30 amSDF - GSP
2 stops12h 35mSouthwest
Sat 9/278:20 amGSP - SDF
1 stop4h 25mSouthwest
Deal found 8/14$413
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/295:30 amSDF - GSP
1 stop4h 25mSouthwest
Mon 9/11:50 pmGSP - SDF
1 stop9h 40mSouthwest
Deal found 8/14$492

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Louisville

Fly to

Greenville

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

7:33 pm-11:52 pm

1 stop4h 19m

Greenville

Mon 10/6

7:41 pm-11:59 pm

1 stop4h 18m

$212

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 9/11

8:10 am-1:28 pm

1 stop5h 18m

Greenville

Mon 9/15

5:30 am-10:00 am

1 stop4h 30m

$245

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 10/3

1:20 pm-7:25 pm

1 stop6h 05m

Greenville

Mon 10/6

1:50 pm-11:40 pm

2 stops9h 50m

$262

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 9/2

7:20 am-11:56 am

1 stop4h 36m

Greenville

Thu 9/4

12:34 pm-6:58 pm

1 stop6h 24m

$292

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 10/16

2:33 pm-9:32 pm

1 stop6h 59m

Greenville

Mon 10/20

7:41 pm-11:59 pm

1 stop4h 18m

$299

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Fri 9/26

4:20 pm-9:00 pm

1 stop4h 40m

Greenville

Mon 9/29

7:40 am-12:30 pm

1 stop4h 50m

$302

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 9/2

11:50 am-7:55 pm

2 stops8h 05m

Greenville

Thu 9/4

1:50 pm-6:35 pm

1 stop4h 45m

$327

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Mon 9/22

7:33 pm-11:52 pm

1 stop4h 19m

Greenville

Sat 9/27

5:30 am-11:43 am

1 stop6h 13m

$348

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Thu 10/16

1:20 pm-7:25 pm

1 stop6h 05m

Greenville

Mon 10/20

1:50 pm-11:40 pm

2 stops9h 50m

$362

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Wed 9/17

7:35 am-12:28 pm

1 stop4h 53m

$88

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 13 results
1
2

Best time to book a flight from Louisville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Greenville

What is the cheapest month to book a flight from Louisville to Greenville?

Currently, January is the cheapest month in which you can book a flight from Louisville to Greenville (average of $329). Flying from Louisville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated August 16, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Louisville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,985 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,985 reviews

Crew

8.5

Boarding

8.2

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Louisville to Greenville round-trip?

    Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $190. Another option worth looking into is Delta, starting at $196 round trip. American Airlines is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Louisville to Greenville one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $88. Southwest flights start at $104 while deals on United Airlines start at $114 one-way.

  • Can I find deals for flights from Louisville to Greenville that include hotel bookings?

    Yes. In addition to deals on Louisville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Greenville.

  • Can I find deals for business class flights from Louisville to Greenville?

    Yes. Cheapflights offers flight deals from Louisville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Louisville to Greenville (average of $329). Flying from Louisville to Greenville in March is currently the most expensive (average of $386). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Louisville to Greenville

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Charlotte flights
Cincinnati to Savannah flights
Nashville to Charleston flights
Cincinnati to Greenville flights
Nashville to Charlotte flights
Cincinnati to Charleston flights
Lexington to Greenville flights
Cincinnati to Myrtle Beach flights
Nashville to Myrtle Beach flights
Nashville to Savannah flights
Louisville to Myrtle Beach flights
Louisville to Charlotte flights
Louisville to Charleston flights
Lexington to Myrtle Beach flights
Lexington to Charlotte flights
Louisville to Savannah flights
Cincinnati to Hilton Head Island flights
Knoxville to Myrtle Beach flights
Nashville to Greenville flights
Lexington to Hilton Head Island flights
Lexington to Savannah flights
Nashville to Columbia flights
Lexington to Charleston flights
Knoxville to Charlotte flights
Knoxville to Savannah flights
Louisville to Columbia flights
Evansville to Charlotte flights
Knoxville to Charleston flights
Nashville to Augusta flights
Nashville to Hilton Head Island flights
Cincinnati to Columbia flights
Knoxville to Hilton Head Island flights
Louisville to Hilton Head Island flights
Lexington to Columbia flights
Huntington to Myrtle Beach flights
Evansville to Charleston flights
Blountville to Myrtle Beach flights
Knoxville to Columbia flights
Evansville to Savannah flights
Cincinnati to Augusta flights
Nashville to Florence flights
Huntington to Charlotte flights
Cincinnati to Florence flights
Blountville to Charlotte flights
Louisville to Augusta flights
Huntington to Columbia flights
Louisville to Florence flights
Evansville to Hilton Head Island flights
Lexington to Augusta flights

Top 2 airlines flying from Louisville to Greenville

Discover the top 2 airlines that operate flights from Louisville to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$190Average$429FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$306FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.