How long is the flight from Louisville to Greenville?

For as low as $257, United Airlines can have you in Greenville from Louisville in 4h 41m. The distance between Louisville and Greenville is about 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Louisville to Greenville round-trip?

Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $190. Another option worth looking into is Delta, starting at $196 round trip. American Airlines is 51% cheaper than the average price of flights available within the next 90 days to this destination.

In terms of precipitation, rainfall in Greenville ranges from 3.6 - 5.1 inches per month. March is typically the wettest month, when rainfall can reach 5.1 in. November is typically the driest time to visit Greenville when rainfall is around 3.6 in.

If weather is an important factor for your trip to Greenville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What is the cheapest time of day to fly from SDF to GSP?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Louisville to Greenville as you normally would.

Most accurate provider : When it comes to deals on Louisville-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Greenville flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Louisville-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Louisville to Greenville that include hotel bookings?

Yes. In addition to deals on Louisville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Louisville to Greenville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Greenville.

Can I find deals for business class flights from Louisville to Greenville?

Yes. Cheapflights offers flight deals from Louisville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$257+ Flights from Louisville to Greenville

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1. Tell us where you want to go

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Cheap flight deals from Louisville to Greenville

Cheapest flights from Louisville to Greenville
Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Wed 12/315:30 amSDF - GSP

1 stop4h 30mSouthwest

Sun 1/48:20 pmGSP - SDF

1 stop4h 10mSouthwest

Deal found 12/27

$535

Sat 12/277:24 pmSDF - GSP

1 stop4h 34mAmerican Airlines

Tue 12/305:00 amGSP - SDF

1 stop3h 50mAmerican Airlines

Deal found 12/27

$985

Best flights from Louisville to Greenville
Discover carefully curated flight deals from Louisville to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 29, 2025.

Tue 1/275:35 amSDF - GSP

1 stop4h 41mUnited Airlines

Tue 2/35:34 pmGSP - SDF

1 stop4h 56mUnited Airlines

Deal found 12/28

$257

Tue 1/2711:50 amSDF - GSP

2 stops8h 00mSouthwest

Tue 2/311:15 amGSP - SDF

1 stop5h 45mSouthwest

Deal found 12/28

$262

Sat 2/2110:46 amSDF - GSP

1 stop6h 58mDelta

Mon 2/237:40 pmGSP - SDF

1 stop4h 18mDelta

Deal found 12/26

$269

Sun 1/113:36 pmSDF - GSP

1 stop17h 22mMultiple Airlines

Thu 1/154:43 pmGSP - SDF

1 stop25h 21mMultiple Airlines

Deal found 12/26

$286

Tue 1/134:32 pmSDF - GSP

1 stop5h 44mAmerican Airlines

Sat 1/176:00 amGSP - SDF

2 stops9h 55mAmerican Airlines

Deal found 12/28

$335

Sat 2/216:40 amSDF - GSP

2 stops5h 40mSouthwest

Mon 2/236:35 pmGSP - SDF

1 stop4h 30mSouthwest

Deal found 12/26

$274

Tue 1/132:10 pmSDF - GSP

1 stop5h 19mUnited Airlines

Sat 1/176:35 amGSP - SDF

1 stop6h 53mUnited Airlines

Deal found 12/28

$330

Sun 2/225:35 amSDF - GSP

1 stop4h 26mUnited Airlines

Thu 2/262:51 pmGSP - SDF

1 stop4h 51mUnited Airlines

Deal found 12/26

$364

Last-minute flights from Louisville to Greenville
Discover last-minute flight deals from Louisville to Greenville. Data last updated December 29, 2025 and is based on user searches.

Wed 12/315:30 amSDF - GSP

1 stop4h 30mSouthwest

Sun 1/48:20 pmGSP - SDF

1 stop4h 10mSouthwest

Deal found 12/27

$535

Sun 1/113:36 pmSDF - GSP

1 stop17h 22mMultiple Airlines

Thu 1/154:43 pmGSP - SDF

1 stop25h 21mMultiple Airlines

Deal found 12/26

$286

Sun 1/112:10 pmSDF - GSP

2 stops9h 38mUnited Airlines

Thu 1/1511:50 amGSP - SDF

2 stops7h 53mUnited Airlines

Deal found 12/26

$501

Tue 1/132:10 pmSDF - GSP

1 stop5h 19mUnited Airlines

Sat 1/176:35 amGSP - SDF

1 stop6h 53mUnited Airlines

Deal found 12/28

$330

Tue 1/134:32 pmSDF - GSP

1 stop5h 44mAmerican Airlines

Sat 1/176:00 amGSP - SDF

2 stops9h 55mAmerican Airlines

Deal found 12/28

$335

Tue 1/136:21 pmSDF - GSP

1 stop4h 03mDelta

Thu 1/158:22 amGSP - SDF

1 stop6h 20mDelta

Deal found 12/27

$431

Tue 1/1311:08 amSDF - GSP

2 stops6h 01mAmerican Airlines

Thu 1/158:09 amGSP - SDF

1 stop4h 16mAmerican Airlines

Deal found 12/27

$436

Tue 1/275:35 amSDF - GSP

1 stop4h 41mUnited Airlines

Tue 2/35:34 pmGSP - SDF

1 stop4h 56mUnited Airlines

Deal found 12/28

$257

Tue 1/2711:50 amSDF - GSP

2 stops8h 00mSouthwest

Tue 2/311:15 amGSP - SDF

1 stop5h 45mSouthwest

Deal found 12/28

$262

One-way flights from Louisville to Greenville
Search for one-way flight options from Louisville to Greenville. Find affordable one-way fares based on user searches. Data last updated December 29, 2025.

Sun 1/46:00 amSDF - GSP

1 stop5h 58mDelta

Deal found 12/28

$279

Sun 1/46:20 amSDF - GSP

2 stops13h 20mSouthwest

Deal found 12/28

$289

Sun 1/42:55 pmSDF - GSP

3 stops29h 13mMultiple Airlines

Deal found 12/28

$422

Find flight deals from Louisville to Greenville

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$257 (United Airlines)
Popular in	February
Cheapest in	September
Average price	$474

Provider with most accurate pricing for Louisville Intl-Greenville flight deals.

Search Deals

Provider most trusted by Cheapflights users for Louisville Intl-Greenville flights.

Search Deals

From Louisville Intl to Greenville

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($95 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 1/27

5:35 am-10:16 am

1 stop4h 41m

Greenville

Tue 2/3

5:34 pm-10:30 pm

1 stop4h 56m

$257

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 1/27

11:50 am-7:50 pm

2 stops8h 00m

Greenville

Tue 2/3

11:15 am-5:00 pm

1 stop5h 45m

$262

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 2/21

10:46 am-5:44 pm

1 stop6h 58m

Greenville

Mon 2/23

7:40 pm-11:58 pm

1 stop4h 18m

$269

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sat 2/21

6:40 am-12:20 pm

2 stops5h 40m

Greenville

Mon 2/23

6:35 pm-11:05 pm

1 stop4h 30m

$274

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 1/11

3:36 pm-8:58 am

1 stop17h 22m

Greenville

Thu 1/15

4:43 pm-6:04 pm

1 stop25h 21m

$286

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 1/13

2:10 pm-7:29 pm

1 stop5h 19m

Greenville

Sat 1/17

6:35 am-1:28 pm

1 stop6h 53m

$330

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Tue 1/13

4:32 pm-10:16 pm

1 stop5h 44m

Greenville

Sat 1/17

6:00 am-3:55 pm

2 stops9h 55m

$335

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 2/22

5:35 am-10:01 am

1 stop4h 26m

Greenville

Thu 2/26

2:51 pm-7:42 pm

1 stop4h 51m

$364

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 1/4

6:00 am-11:58 am

1 stop5h 58m

$279

LouisvilleGreenville

SDF - GSP

SDFGSP

Louisville Intl

Sun 1/4

6:20 am-7:40 pm

2 stops13h 20m

$289

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 11 results

Compare providers for flights from Louisville to Greenville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Greenville in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Louisville-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Greenville flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Louisville-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Louisville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Greenville

What is the cheapest month to book a flight from Louisville to Greenville?

Currently, September is the cheapest month in which you can book a flight from Louisville to Greenville (average of $128). Flying from Louisville to Greenville in January is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Read reviews from past customers who have flown Delta and American Airlines from Louisville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,014 reviews

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,072 reviews

Delta

7.9

Good

8,014 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Louisville to Greenville?
For as low as $257, United Airlines can have you in Greenville from Louisville in 4h 41m. The distance between Louisville and Greenville is about 299 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Louisville to Greenville round-trip?
Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $190. Another option worth looking into is Delta, starting at $196 round trip. American Airlines is 51% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Louisville to Greenville that include hotel bookings?
Yes. In addition to deals on Louisville to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Louisville to Greenville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Greenville.
Can I find deals for business class flights from Louisville to Greenville?
Yes. Cheapflights offers flight deals from Louisville to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Louisville to Greenville?
Currently, September is the cheapest month in which you can book a flight from Louisville to Greenville (average of $128). Flying from Louisville to Greenville in January is currently the most expensive (average of $215). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Simpsonville

Duncan

Greer

Seneca

Anderson

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Louisville to Greenville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$190	Average$291	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$196	Average$306	FlexibilityNo cancel fee	On-timeN/A

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$257+ Cheap flights from Louisville to Greenville (SDF - GSP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Louisville to Greenville with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Louisville to Greenville

Cheapest flights from Louisville to GreenvilleExplore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.

Find flight deals from Louisville to Greenville

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Greenville that are best for you.

Compare providers for flights from Louisville to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Greenville in December.

Best time to book a flight from Louisville to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Louisville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Greenville

What is the cheapest month to book a flight from Louisville to Greenville?

Reviews of airlines servicing Greenville

Read reviews from past customers who have flown Delta and American Airlines from Louisville to Greenville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Louisville to Greenville?

What are the cheapest airlines flying from Louisville to Greenville round-trip?

Can I find deals for flights from Louisville to Greenville that include hotel bookings?

How can I find direct flights from Louisville to Greenville?

Can I find deals for business class flights from Louisville to Greenville?

What is the cheapest month to book a flight from Louisville to Greenville?

Traveling to a place near Greenville?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Louisville to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Louisville to Greenville

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Cheapest flights from Louisville to Greenville
Explore the most affordable flight options available from Louisville to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 29, 2025.