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Gainesville

$264+ Cheap flights from Iowa to Gainesville (GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GNV
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from Iowa to Gainesville

Best flights from Iowa to Gainesville
Discover carefully curated flight deals from Iowa to Gainesville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/33:07 pmOMA - GNV
1 stop7h 23mAmerican Airlines
Tue 2/107:12 amGNV - OMA
1 stop6h 28mAmerican Airlines
Deal found 12/27$271
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/237:00 amOMA - GNV
1 stop4h 26mDelta
Tue 1/2710:11 amGNV - OMA
1 stop7h 36mDelta
Deal found 12/26$359
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:17 pmOMA - GNV
1 stop6h 08mAmerican Airlines
Sat 2/215:45 pmGNV - OMA
1 stop7h 30mAmerican Airlines
Deal found 12/28$337
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/138:00 amOMA - GNV
1 stop4h 26mDelta
Sat 1/172:24 pmGNV - OMA
1 stop5h 46mDelta
Deal found 12/27$383
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/233:07 pmOMA - GNV
1 stop7h 23mAmerican Airlines
Tue 1/276:00 amGNV - OMA
2 stops11h 50mAmerican Airlines
Deal found 12/26$364
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:15 pmMLI - GNV
1 stop4h 22mDelta
Wed 3/184:59 pmGNV - MLI
1 stop6h 31mDelta
Deal found 12/26$407
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/611:35 amDSM - GNV
2 stops11h 22mAmerican Airlines
Sun 2/84:30 pmGNV - DSM
1 stop7h 53mAmerican Airlines
Deal found 12/26$426
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:01 pmMLI - GNV
1 stop4h 33mDelta
Thu 2/261:15 pmGNV - MLI
1 stop4h 01mDelta
Deal found 12/26$427
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:24 pmCID - GNV
1 stop8h 35mAmerican Airlines
Sat 3/217:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/25$435
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:00 amMLI - GNV
1 stop4h 06mDelta
Sun 5/177:05 pmGNV - MLI
1 stop4h 26mDelta
Deal found 12/26$453
This Delta deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:45 amCID - GNV
1 stop5h 38mDelta
Sun 5/174:59 pmGNV - CID
1 stop5h 51mDelta
Deal found 12/27$463
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 amCID - GNV
2 stops10h 18mAmerican Airlines
Sat 3/217:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/26$477
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:02 pmMLI - GNV
2 stops8h 57mAmerican Airlines
Wed 3/186:24 amGNV - MLI
1 stop6h 44mAmerican Airlines
Deal found 12/26$502
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:33 amDSM - GNV
1 stop5h 42mDelta
Mon 3/234:59 pmGNV - DSM
1 stop18h 49mDelta
Deal found 12/26$532
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:24 pmCID - GNV
1 stop8h 35mAmerican Airlines
Sat 3/217:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/26$528
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:15 pmMLI - GNV
1 stop4h 22mDelta
Sat 3/215:34 pmGNV - MLI
1 stop5h 56mDelta
Deal found 12/26$562
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:24 pmCID - GNV
1 stop8h 35mAmerican Airlines
Wed 3/186:24 amGNV - CID
2 stops9h 09mAmerican Airlines
Deal found 12/26$533
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:20 pmDSM - GNV
1 stop4h 17mDelta
Mon 3/234:59 pmGNV - DSM
1 stop18h 49mDelta
Deal found 12/26$574
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:24 pmCID - GNV
1 stop8h 35mAmerican Airlines
Fri 3/207:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/26$538
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:02 pmMLI - GNV
2 stops8h 57mAmerican Airlines
Thu 3/193:08 pmGNV - MLI
1 stop7h 50mAmerican Airlines
Deal found 12/26$542
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:00 amMLI - GNV
1 stop5h 47mDelta
Sun 3/227:00 pmGNV - MLI
1 stop4h 30mDelta
Deal found 12/26$598
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 amMLI - GNV
1 stop5h 47mDelta
Wed 3/184:59 pmGNV - MLI
1 stop6h 31mDelta
Deal found 12/26$598
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1412:44 pmMLI - GNV
1 stop5h 36mAmerican Airlines
Thu 3/193:08 pmGNV - MLI
1 stop7h 50mAmerican Airlines
Deal found 12/26$557
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:20 amCID - GNV
1 stop6h 27mDelta
Wed 3/187:00 pmGNV - CID
1 stop4h 19mDelta
Deal found 12/26$609
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/151:24 pmCID - GNV
1 stop8h 35mAmerican Airlines
Sat 3/217:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/26$561
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1410:04 amCID - GNV
2 stops11h 23mAmerican Airlines
Fri 3/207:17 amGNV - CID
1 stop6h 22mAmerican Airlines
Deal found 12/26$579
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 amCID - GNV
2 stops10h 18mAmerican Airlines
Sun 3/223:08 pmGNV - CID
2 stops9h 13mAmerican Airlines
Deal found 12/26$607
This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:46 amDSM - GNV
2 stops9h 34mAmerican Airlines
Sun 3/14:19 pmGNV - DSM
1 stop8h 19mAmerican Airlines
Deal found 12/27$608
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1512:41 pmMLI - GNV
1 stop5h 39mAmerican Airlines
Wed 3/186:00 amGNV - MLI
2 stops8h 22mAmerican Airlines
Deal found 12/26$608
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:00 pmDSM - GNV
1 stop6h 28mAmerican Airlines
Mon 3/236:24 amGNV - DSM
1 stop7h 53mAmerican Airlines
Deal found 12/26$626

Find flight deals from Iowa to Gainesville

Keep the following information in mind while searching for Iowa to Gainesville flight deals. Data was last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$271
(American Airlines)

One-way from

$264
(Delta)
Provider with most accurate pricing for Des Moines-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gainesville Regional flights.
Search Deals
From Iowa to Gainesville Regional
Search Deals
One-way flight from Iowa to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Iowa to Gainesville that are best for you.

Fly from

Iowa

Fly to

Gainesville

Route

Depart

Return

Price

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Tue 2/3

3:07 pm-11:30 pm

1 stop7h 23m

Gainesville Regional

Tue 2/10

7:12 am-12:40 pm

1 stop6h 28m

$271

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Thu 2/19

5:17 pm-12:25 am

1 stop6h 08m

Gainesville Regional

Sat 2/21

5:45 pm-12:15 am

1 stop7h 30m

$337

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Fri 1/23

7:00 am-12:26 pm

1 stop4h 26m

Gainesville Regional

Tue 1/27

10:11 am-4:47 pm

1 stop7h 36m

$359

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Fri 1/23

3:07 pm-11:30 pm

1 stop7h 23m

Gainesville Regional

Tue 1/27

6:00 am-4:50 pm

2 stops11h 50m

$364

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Tue 1/13

8:00 am-1:26 pm

1 stop4h 26m

Gainesville Regional

Sat 1/17

2:24 pm-7:10 pm

1 stop5h 46m

$383

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Wed 3/11

5:15 pm-10:37 pm

1 stop4h 22m

Gainesville Regional

Wed 3/18

4:59 pm-10:30 pm

1 stop6h 31m

$407

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Fri 2/6

11:35 am-11:57 pm

2 stops11h 22m

Gainesville Regional

Sun 2/8

4:30 pm-11:23 pm

1 stop7h 53m

$426

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Fri 2/20

5:01 pm-10:34 pm

1 stop4h 33m

Gainesville Regional

Thu 2/26

1:15 pm-4:16 pm

1 stop4h 01m

$427

Cedar RapidsGainesville

CID - GNV

CIDGNV

Cedar Rapids

Sat 3/14

1:24 pm-10:59 pm

1 stop8h 35m

Gainesville Regional

Sat 3/21

7:17 am-12:39 pm

1 stop6h 22m

$435

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Thu 5/14

11:00 am-4:06 pm

1 stop4h 06m

Gainesville Regional

Sun 5/17

7:05 pm-10:31 pm

1 stop4h 26m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Showing 1-10 of 34 results
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Best time to book a flight from Iowa to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Gainesville

What is the cheapest month to book a flight from Iowa to Gainesville?

Currently, October is the cheapest month in which you can book a flight from Iowa to Gainesville (average of $42). Flying from Iowa to Gainesville in December is currently the most expensive (average of $170). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from Iowa?

    Gainesville Regional (GNV), located 4.2 mi from the city center, is the airport you fly into when you book flights from Iowa to Gainesville.

  • How long is the flight from Iowa to Gainesville?

    Airlines like American Airlines and Delta fly from Iowa to Gainesville in about 4h 22m. The time it takes to get you to your destination can typically vary by up to 3h 01m. There are 933 mi between Iowa and Gainesville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Gainesville?

    The most popular route from Iowa to Gainesville is Omaha Eppley Airfield - Gainesville Regional. You may also consider Cedar Rapids - Gainesville Regional or Des Moines - Gainesville Regional.

  • Can I find deals for flights from Iowa to Gainesville that include hotel bookings?

    Yes. In addition to deals on Iowa to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Gainesville.

  • Can I find deals for business class flights from Iowa to Gainesville?

    Yes. Cheapflights offers flight deals from Iowa to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Gainesville?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Gainesville (average of $42). Flying from Iowa to Gainesville in December is currently the most expensive (average of $170). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Alternative routes for Iowa to Gainesville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Gainesville

Discover the top 2 airlines that operate flights from Iowa to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$318Average$566FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$323Average$449FlexibilityNo cancel feeOn-time71%

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