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Gainesville

$377+ Cheap flights from Iowa to Gainesville (GNV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GNV
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheap flight deals from Iowa to Gainesville

Cheapest flights from Iowa to Gainesville
Explore the most affordable flight options available from Iowa to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:35 am
DSM
-
GNV
1 stop5h 50m
Delta
Wed 7/810:17 am
GNV
-
DSM
1 stop4h 17m
Delta
Deal found 5/4$377
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:04 am
DSM
-
GNV
1 stop5h 16m
American Airlines
Wed 7/89:48 am
GNV
-
DSM
2 stops11h 30m
American Airlines
Deal found 5/4$382
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:56 am
MLI
-
GNV
1 stop5h 26m
Delta
Tue 6/91:11 pm
GNV
-
MLI
1 stop4h 26m
Delta
Deal found 5/1$403
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:45 am
OMA
-
GNV
1 stop5h 38m
Delta
Sat 8/81:08 pm
GNV
-
OMA
1 stop6h 44m
Delta
Deal found 5/5$403
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:24 pm
MLI
-
GNV
1 stop7h 09m
American Airlines
Tue 6/96:30 am
GNV
-
MLI
2 stops10h 36m
American Airlines
Deal found 5/1$408
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/64:00 pm
DSM
-
GNV
1 stop5h 44m
Delta
Sat 6/135:36 pm
GNV
-
DSM
1 stop5h 55m
Delta
Deal found 5/3$418
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 am
DSM
-
GNV
1 stop5h 37m
Delta
Sat 9/194:59 pm
GNV
-
DSM
1 stop6h 27m
Delta
Deal found 5/1$422
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:05 am
DSM
-
GNV
1 stop4h 56m
American Airlines
Sat 9/191:54 pm
GNV
-
DSM
1 stop4h 45m
American Airlines
Deal found 5/5$429
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:17 pm
MLI
-
GNV
1 stop4h 27m
Delta
Tue 6/27:05 pm
GNV
-
MLI
1 stop4h 16m
Delta
Deal found 5/1$435
This Delta deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:45 am
OMA
-
GNV
1 stop5h 38m
Delta
Sun 8/96:10 am
GNV
-
OMA
1 stop4h 32m
Delta
Deal found 5/5$435
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/264:24 pm
MLI
-
GNV
1 stop7h 09m
American Airlines
Tue 6/26:30 am
GNV
-
MLI
2 stops10h 36m
American Airlines
Deal found 5/1$440
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:25 pm
OMA
-
GNV
2 stops8h 51m
American Airlines
Mon 10/198:05 pm
GNV
-
OMA
1 stop5h 04m
American Airlines
Deal found 5/3$440

Find flight deals from Iowa to Gainesville

Keep the following information in mind while searching for Iowa to Gainesville flight deals. Data was last updated May 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$377
(Delta)
Provider with most accurate pricing for Des Moines-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gainesville Regional flights.
Search Deals
From Iowa to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Iowa to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Sat 7/4

5:35 am-12:25 pm

1 stop5h 50m

Gainesville Regional

Wed 7/8

10:17 am-1:34 pm

1 stop4h 17m

$377

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Sat 7/4

7:04 am-1:20 pm

1 stop5h 16m

Gainesville Regional

Wed 7/8

9:48 am-8:18 pm

2 stops11h 30m

$382

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Tue 6/2

5:56 am-12:22 pm

1 stop5h 26m

Gainesville Regional

Tue 6/9

1:11 pm-4:37 pm

1 stop4h 26m

$403

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Tue 6/2

4:24 pm-12:33 am

1 stop7h 09m

Gainesville Regional

Tue 6/9

6:30 am-4:06 pm

2 stops10h 36m

$408

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Sat 6/6

4:00 pm-10:44 pm

1 stop5h 44m

Gainesville Regional

Sat 6/13

5:36 pm-10:31 pm

1 stop5h 55m

$418

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Thu 9/10

5:45 am-12:22 pm

1 stop5h 37m

Gainesville Regional

Sat 9/19

4:59 pm-10:26 pm

1 stop6h 27m

$422

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Thu 9/10

7:05 am-1:01 pm

1 stop4h 56m

Gainesville Regional

Sat 9/19

10:40 am-5:39 pm

1 stop7h 59m

$429
Quickest round-trip

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Tue 5/26

5:17 pm-10:44 pm

1 stop4h 27m

Gainesville Regional

Tue 6/2

7:05 pm-10:21 pm

1 stop4h 16m

$435

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Tue 8/4

2:41 pm-10:48 pm

1 stop7h 07m

Gainesville Regional

Sun 8/9

6:10 am-9:42 am

1 stop4h 32m

$435

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Sat 10/17

5:35 am-12:22 pm

1 stop5h 47m

Gainesville Regional

Mon 10/19

7:05 pm-12:07 am

1 stop6h 02m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/4

Showing 1-10 of 29 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Gainesville
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from Iowa?

    Gainesville Regional (GNV), located 4.2 mi from the city center, is the airport you fly into when you book flights from Iowa to Gainesville.

  • How long is the flight from Iowa to Gainesville?

    Airlines like Delta and American Airlines fly from Iowa to Gainesville in about 5h 16m. The time it takes to get you to your destination can typically vary by up to 34m. There are 1036 mi between Iowa and Gainesville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Gainesville?

    The most popular route from Iowa to Gainesville is Omaha Eppley Airfield - Gainesville Regional. You may also consider Des Moines - Gainesville Regional or Moline Quad-City - Gainesville Regional.

  • Can I find deals for flights from Iowa to Gainesville that include hotel bookings?

    Yes. In addition to deals on Iowa to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Gainesville.

  • Can I find deals for business class flights from Iowa to Gainesville?

    Yes. Cheapflights offers flight deals from Iowa to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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