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Gainesville

$358+ Cheap flights from Iowa to Gainesville (GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GNV
Aug 2 — Aug 91
Sun 8/2
Sun 8/9
1 adult, Economy
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Cheap flight deals from Iowa to Gainesville

Cheapest flights from Iowa to Gainesville
Explore the most affordable flight options available from Iowa to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.

This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:11 pm
DSM
-
GNV
1 stop4h 17m
Delta
Tue 8/1110:12 am
GNV
-
DSM
2 stops11h 27m
Delta
Deal found 6/29$382
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
CID
-
GNV
1 stop5h 23m
Delta
Tue 8/117:01 pm
GNV
-
CID
1 stop4h 22m
Delta
Deal found 6/30$403
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
MLI
-
GNV
1 stop5h 23m
Delta
Wed 8/1210:12 am
GNV
-
MLI
1 stop7h 10m
Delta
Deal found 6/30$403
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:00 pm
OMA
-
GNV
1 stop4h 28m
Delta
Wed 8/196:00 am
GNV
-
OMA
1 stop4h 42m
Delta
Deal found 6/30$403
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:20 pm
MLI
-
GNV
1 stop6h 56m
American Airlines
Tue 8/112:51 pm
GNV
-
MLI
2 stops10h 17m
American Airlines
Deal found 6/30$408
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:11 pm
DSM
-
GNV
1 stop4h 17m
Delta
Mon 8/107:01 pm
GNV
-
DSM
1 stop4h 36m
Delta
Deal found 6/29$422
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:17 am
CID
-
GNV
1 stop6h 03m
American Airlines
Tue 8/117:04 am
GNV
-
CID
1 stop5h 33m
American Airlines
Deal found 6/30$425
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/109:47 am
DSM
-
GNV
1 stop6h 00m
American Airlines
Sat 9/197:33 am
GNV
-
DSM
1 stop5h 31m
American Airlines
Deal found 6/30$429
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
CID
-
GNV
1 stop5h 23m
Delta
Wed 8/127:01 pm
GNV
-
CID
1 stop4h 22m
Delta
Deal found 6/30$431
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
MLI
-
GNV
1 stop5h 23m
Delta
Sat 8/81:08 pm
GNV
-
MLI
1 stop4h 14m
Delta
Deal found 6/30$431
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/25:50 am
CID
-
GNV
1 stop5h 33m
Delta
Sat 8/85:35 pm
GNV
-
CID
1 stop5h 48m
Delta
Deal found 6/30$435
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
MLI
-
GNV
1 stop5h 23m
Delta
Thu 8/136:00 am
GNV
-
MLI
1 stop5h 25m
Delta
Deal found 6/30$435

Find flight deals from Iowa to Gainesville

Keep the following information in mind while searching for Iowa to Gainesville flight deals. Data was last updated July 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$382
(Delta)

One-way from

$358
(American Airlines)
Provider with most accurate pricing for Des Moines-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Gainesville Regional flights.
Search Deals
From Iowa to Gainesville Regional
Search Deals
One-way flight from Iowa to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from Iowa to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Sat 8/8

4:11 pm-9:28 pm

1 stop4h 17m

Gainesville Regional

Tue 8/11

10:12 am-8:39 pm

2 stops11h 27m

$382

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Wed 8/5

4:13 pm-10:42 pm

1 stop5h 29m

Gainesville Regional

Sun 8/9

5:45 am-12:49 pm

1 stop8h 04m

$429

Des MoinesGainesville

DSM - GNV

DSMGNV

Des Moines

Thu 9/10

9:47 am-4:47 pm

1 stop6h 00m

Gainesville Regional

Sat 9/19

7:33 am-12:04 pm

1 stop5h 31m

$429

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Wed 8/5

6:00 am-12:23 pm

1 stop5h 23m

Gainesville Regional

Sat 8/8

6:00 am-10:25 am

1 stop5h 25m

$431

MolineGainesville

MLI - GNV

MLIGNV

Moline Quad-City

Wed 8/5

6:00 am-12:23 pm

1 stop5h 23m

Gainesville Regional

Sun 8/9

6:00 am-10:25 am

1 stop5h 25m

$435

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Mon 8/10

7:08 am-12:23 pm

1 stop4h 15m

Gainesville Regional

Sat 8/15

6:00 am-10:54 am

1 stop5h 54m

$435
Quickest round-trip

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Fri 8/7

7:08 am-12:23 pm

1 stop4h 15m

Gainesville Regional

Wed 8/12

6:00 am-9:42 am

1 stop4h 42m

$435

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Tue 8/11

5:45 am-12:23 pm

1 stop5h 38m

Gainesville Regional

Mon 8/17

6:00 am-9:42 am

1 stop4h 42m

$435

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Wed 7/29

5:25 am-12:23 pm

1 stop5h 58m

Gainesville Regional

Tue 8/4

6:00 am-9:42 am

1 stop4h 42m

$440

OmahaGainesville

OMA - GNV

OMAGNV

Omaha Eppley Airfield

Wed 7/29

11:48 am-11:59 pm

2 stops11h 11m

Gainesville Regional

Wed 8/5

6:39 pm-11:38 pm

1 stop5h 59m

$464

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 33 resultsSorted by cheapest first
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Best time to book a flight from Iowa to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Gainesville
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Gainesville from Iowa?

    Gainesville Regional (GNV), located 4.2 mi from the city center, is the airport you fly into when you book flights from Iowa to Gainesville.

  • How long is the flight from Iowa to Gainesville?

    Airlines like Delta and American Airlines fly from Iowa to Gainesville in about 4h 17m. The time it takes to get you to your destination can typically vary by up to 1h 12m. There are 1036 mi between Iowa and Gainesville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Iowa to Gainesville?

    The most popular route from Iowa to Gainesville is Des Moines - Gainesville Regional. You may also consider Cedar Rapids - Gainesville Regional or Omaha Eppley Airfield - Gainesville Regional.

  • Can I find deals for flights from Iowa to Gainesville that include hotel bookings?

    Yes. In addition to deals on Iowa to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Gainesville.

  • Can I find deals for business class flights from Iowa to Gainesville?

    Yes. Cheapflights offers flight deals from Iowa to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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