In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from W1L to FLO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Wilkes-Barre to Florence, South Carolina as you normally would.

What airport do you fly into for flights to Florence from Wilkes-Barre?

Located just 2.3 mi from the city center, Florence is the airport most travelers will use when flying to Florence from Wilkes-Barre. Booking flights from Wilkes-Barre to Florence (FLO) should be relatively easy as there are 0 daily inbound flights from Wilkes-Barre from 0 different airlines.

Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?

Yes. In addition to deals on Wilkes-Barre to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Wilkes-Barre to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Florence.

Can I find deals for business class flights from Wilkes-Barre to Florence?

Yes. Cheapflights offers flight deals from Wilkes-Barre to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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What airport do you fly into for flights to Florence from Wilkes-Barre?
Located just 2.3 mi from the city center, Florence is the airport most travelers will use when flying to Florence from Wilkes-Barre. Booking flights from Wilkes-Barre to Florence (FLO) should be relatively easy as there are 0 daily inbound flights from Wilkes-Barre from 0 different airlines.
Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?
Yes. In addition to deals on Wilkes-Barre to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Wilkes-Barre to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Florence.
Can I find deals for business class flights from Wilkes-Barre to Florence?
Yes. Cheapflights offers flight deals from Wilkes-Barre to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Find cheap flights from Wilkes-Barre to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Related info for your journey

What airport do you fly into for flights to Florence from Wilkes-Barre?

Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?

How can I find direct flights from Wilkes-Barre to Florence?

Can I find deals for business class flights from Wilkes-Barre to Florence?

Traveling to a place near Florence?

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Complete your trip

Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Wilkes-Barre to Florence by cabin class

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Other flights to Florence

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Cheap flights from Wilkes-Barre, PA to Florence, SC (FLO)

Find cheap flights from Wilkes-Barre to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Related info for your journey

What airport do you fly into for flights to Florence from Wilkes-Barre?

Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?

How can I find direct flights from Wilkes-Barre to Florence?

Can I find deals for business class flights from Wilkes-Barre to Florence?

Traveling to a place near Florence?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Wilkes-Barre to Florence

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Wilkes-Barre to Florence by cabin class

Find flights from Wilkes-Barre to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Other flights to Florence

Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 6, 2026.

Wilkes-Barre and Florence flights

Browse other Wilkes-Barre and Florence flight options. Last updated on September 6, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Wilkes-Barre to Florence flights

Consider these flights traveling from Wilkes-Barre to Florence.

100% Free

Book with Flexibility

Travel Smart