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$424+ Cheap flights from Wilkes-Barre, PA to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
ABE — FLO
Aug 7 — Aug 141
Fri 8/7
Fri 8/14
1 adult, Economy
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Cheap flight deals from Wilkes-Barre to Florence

Cheapest flights from Wilkes-Barre to Florence
Explore the most affordable flight options available from Wilkes-Barre to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.

This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:34 pm
AVP
-
FLO
2 stops20h 22m
American Airlines
Tue 8/256:22 am
FLO
-
AVP
2 stops11h 41m
American Airlines
Deal found 7/4$605

Find flight deals from Wilkes-Barre to Florence

Keep the following information in mind while searching for Wilkes-Barre to Florence flight deals. Data was last updated July 8, 2026.

Round-trip from

$605
(American Airlines)

One-way from

$424
(American Airlines)
From Wilkes-Barre to Florence
Search Deals
One-way flight from Wilkes-Barre to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilkes-Barre to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Wilkes-Barre to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ScrantonFlorence

AVP - FLO

AVPFLO

Wilkes-Barre Scranton

Fri 8/14

6:34 pm-2:56 pm

2 stops20h 22m

Florence

Tue 8/25

6:22 am-6:03 pm

2 stops11h 41m

$605
Cheapest one-way
Quickest one-way

ScrantonFlorence

AVP - FLO

AVPFLO

Wilkes-Barre Scranton

Wed 7/22

5:27 pm-11:37 pm

1 stop6h 10m

$424

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/7

Sorted by cheapest first

Best time to book a flight from Wilkes-Barre to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Wilkes-Barre with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilkes-Barre to Florence
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Wilkes-Barre to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Wilkes-Barre?

    Located just 2.3 mi from the city center, Florence is the airport most travelers will use when flying to Florence from Wilkes-Barre. Booking flights from Wilkes-Barre to Florence (FLO) should be relatively easy as there are 0 daily inbound flights from Wilkes-Barre from 0 different airlines.

  • How long is the flight from Wilkes-Barre to Florence, South Carolina?

    American Airlines can get you from Wilkes-Barre to Florence, South Carolina in just under 20h 22m. Your travel time can differ by up to . The distance between Wilkes-Barre and Florence, South Carolina is about 540 mi.

  • Can I find deals for flights from Wilkes-Barre to Florence that include hotel bookings?

    Yes. In addition to deals on Wilkes-Barre to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilkes-Barre to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilkes-Barre to Florence.

  • Can I find deals for business class flights from Wilkes-Barre to Florence?

    Yes. Cheapflights offers flight deals from Wilkes-Barre to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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