$563+ Cheap flights from Syracuse to Florence, SC (SYR - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — FLO
Aug 9 — Aug 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Florence
Cheapest
Best
Last-minute
Cheapest flights from Syracuse to FlorenceExplore the most affordable flight options available from Syracuse to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Syracuse to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sat 8/293:22 pm
FLO
- SYR
1 stop6h 32m
American Airlines
Deal found 7/10![American Airlines logo]()
$563
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sat 8/296:22 am
FLO
- SYR
1 stop5h 58m
American Airlines
Deal found 7/10![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sun 8/302:37 pm
FLO
- SYR
1 stop4h 16m
American Airlines
Deal found 7/10![American Airlines logo]()
$649
Best flights from Syracuse to FlorenceDiscover carefully curated flight deals from Syracuse to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Syracuse to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sat 8/296:22 am
FLO
- SYR
1 stop5h 58m
American Airlines
Deal found 7/10![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
SYR
- FLO
2 stops8h 56m
American Airlines
Sat 8/293:22 pm
FLO
- SYR
1 stop6h 32m
American Airlines
Deal found 7/10![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
SYR
- FLO
2 stops8h 56m
American Airlines
Sun 8/305:05 am
FLO
- SYR
1 stop6h 16m
American Airlines
Deal found 7/10![American Airlines logo]()
$687
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/233:29 pm
SYR
- FLO
2 stops8h 29m
American Airlines
Sat 8/296:22 am
FLO
- SYR
2 stops8h 42m
American Airlines
Deal found 7/10![American Airlines logo]()
$819
Last-minute flights from Syracuse to FlorenceDiscover last-minute flight deals from Syracuse to Florence. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Syracuse to Florence. Data last updated July 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sat 8/296:22 am
FLO
- SYR
1 stop5h 58m
American Airlines
Deal found 7/10![American Airlines logo]()
$606
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sun 8/302:37 pm
FLO
- SYR
1 stop4h 16m
American Airlines
Deal found 7/10![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:17 pm
SYR
- FLO
1 stop5h 42m
American Airlines
Sat 8/293:22 pm
FLO
- SYR
1 stop6h 32m
American Airlines
Deal found 7/10![American Airlines logo]()
$563
Find flight deals from Syracuse to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $563 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Syracuse to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
SyracuseFlorence
SYR - FLO
SYRFLO
Syracuse Hancock Intl
Fri 8/21
5:17 pm-10:59 pm
1 stop5h 42m
Florence
Sat 8/29
6:22 am-12:20 pm
1 stop5h 58m
$606
SyracuseFlorence
SYR - FLO
SYRFLO
Syracuse Hancock Intl
Sat 8/22
6:00 am-2:56 pm
2 stops8h 56m
Florence
Sat 8/29
3:22 pm-9:54 pm
1 stop6h 32m
$644
SyracuseFlorence
SYR - FLO
SYRFLO
Syracuse Hancock Intl
Sat 8/22
6:00 am-2:56 pm
2 stops8h 56m
Florence
Sun 8/30
5:05 am-11:21 am
1 stop6h 16m
$687
SyracuseFlorence
SYR - FLO
SYRFLO
Syracuse Hancock Intl
Sun 8/23
3:29 pm-11:58 pm
2 stops8h 29m
Florence
Sat 8/29
6:22 am-3:04 pm
2 stops8h 42m
$819
Sorted by cheapest first
Compare providers for flights from Syracuse to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Florence in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Syracuse with our price prediction graph.
SYR-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 10, 2026.
Get a feel of what it's like to fly with American Airlines from Syracuse to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Crew
7.9
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Overall
7.1
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Food
6.4
Crew
7.9
Entertainment
6.8
Boarding
7.5
Comfort
7.2
Overall
7.1
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top airline flying from Syracuse to Florence
Discover the top airline that operate flights from Syracuse to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$412 | Average$516 | FlexibilityNo cancel fee | On-time71% |