$312+ Cheap flights from Syracuse to Florence, SC (SYR - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — FLO
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Syracuse to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Syracuse to Florence
One-way
One-way flights from Syracuse to FlorenceSearch for one-way flight options from Syracuse to Florence. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Syracuse to Florence. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:27 pm -
1 stop6h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:30 pm -
1 stop4h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![American Airlines logo]()
$348
Find flight deals from Syracuse to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Syracuse (SYR) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Cheapflights Fare Finder
Customize your flight search to find flights from Syracuse to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Syracuse to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SyracuseFlorence
SYR Syracuse Hancock Intl - FLO Florence
SYRFLO
Syracuse Hancock Intl
Wed 11/18
4:27 pm-10:59 pm
1 stop6h 32m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$312
Quickest round-trip
SyracuseFlorence
SYR Syracuse Hancock Intl - FLO Florence
SYRFLO
Syracuse Hancock Intl
Thu 11/19
7:30 pm-11:54 pm
1 stop4h 24m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$348
Sorted by cheapest first
Compare providers for flights from Syracuse to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Syracuse to Florence in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Syracuse-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Syracuse-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Syracuse-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Syracuse-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Syracuse-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Syracuse to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Syracuse with our price prediction graph.
SYR-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 14, 2026.
Get a feel of what it's like to fly with American Airlines from Syracuse to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Boarding
7.4
Entertainment
6.8
Crew
7.9
Food
6.4
Comfort
7.2
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Overall
7.1
Boarding
7.4
Entertainment
6.8
Crew
7.9
Food
6.4
Comfort
7.2
Reviews
1 / 20
2.0
MediocreHiram K,Sep 2023
JFK - CLT
Related info for your journey
Find useful and relevant information for your journey from Syracuse to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top airline flying from Syracuse to Florence
Discover the top airline that operate flights from Syracuse to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$412 | Average$552 | FlexibilityNo cancel fee | On-time71% |