
Keep the following information in mind while searching for Syracuse to South Carolina flight deals. Data was last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $96 (Kiwi.com) |
One-way from | $80 (CheapOair) |
Popular in | December |
Cheapest in | September |
Average price | $187 |
Good round-trip deal | $101 or less |
Good one-way deal | $134 or less |
Fly from
Fly to
Route
Depart
Return
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 12/11
9:21 pm-11:42 pm
Nonstop2h 21m
Charleston
Mon 12/14
6:30 am-8:39 am
Nonstop2h 09m
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 12/4
9:21 pm-11:42 pm
Nonstop2h 21m
Charleston
Mon 12/7
6:30 am-8:39 am
Nonstop2h 09m
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 11/13
9:21 pm-11:42 pm
Nonstop2h 21m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 12/25
9:21 pm-11:42 pm
Nonstop2h 21m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 12/25
6:00 am-12:39 pm
1 stop6h 39m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseGreenville
SYR Syracuse Hancock Intl - GSP Greenville
SYRGSP
Syracuse Hancock Intl
Wed 11/25
7:30 pm-11:31 pm
1 stop4h 01m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseGreenville
SYR Syracuse Hancock Intl - GSP Greenville
SYRGSP
Syracuse Hancock Intl
Wed 12/9
12:02 pm-10:02 am
1 stop22h 00m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseGreenville
SYR Syracuse Hancock Intl - GSP Greenville
SYRGSP
Syracuse Hancock Intl
Sat 11/7
3:20 pm-8:13 am
2 stops40h 53m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseGreenville
SYR Syracuse Hancock Intl - GSP Greenville
SYRGSP
Syracuse Hancock Intl
Sat 11/7
3:20 pm-8:13 am
3 stops40h 53m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
SyracuseCharleston
SYR Syracuse Hancock Intl - CHS Charleston
SYRCHS
Syracuse Hancock Intl
Fri 11/13
5:23 pm-8:38 am
1 stop15h 15m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
Everything you need to know about your flight from Syracuse to South Carolina
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Food
Boarding
Comfort
Entertainment
Overall
Crew
Reviews
James,Oct 2026
RSW - RDU
Find useful and relevant information for your journey from Syracuse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$98 | Average$174 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$107 | Average$192 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$116 | Average$367 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$131 | Average$239 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$195 | Average$374 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$230 | Average$412 | FlexibilityNo cancel fee | On-time71% |