How long is the flight from Florence, South Carolina to Syracuse?

There are many flights that can get you from Florence, South Carolina to Syracuse in 5h 45m. Fly via American Airlines to get the fastest option. There are 646 mi between Florence, South Carolina and Syracuse.

In terms of precipitation, rainfall in Syracuse ranges from 2.1 - 3.8 inches per month. July is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Syracuse when rainfall is around 2.1 in.

If weather is an important factor for your trip to Syracuse, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What is the cheapest time of day to fly from FLO to SYR?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florence, South Carolina to Syracuse as you normally would.

Most accurate provider : When it comes to deals on Florence, South Carolina-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Syracuse flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Florence, South Carolina-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Florence to Syracuse that include hotel bookings?

Yes. In addition to deals on Florence to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Florence to Syracuse?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Syracuse.

Can I find deals for business class flights from Florence to Syracuse?

Yes. Cheapflights offers flight deals from Florence to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$636+ Cheap Flights from Florence, SC to Syracuse

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Cheap flight deals from Florence to Syracuse

Cheapest

Best

Cheapest flights from Florence to Syracuse
Explore the most affordable flight options available from Florence to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.

Sat 11/215:09 am -

1 stop5h 45m

Sun 11/295:27 pm -

1 stop6h 27m

Deal found 9/13

$636

Sat 11/215:09 am -

1 stop5h 45m

Sat 11/284:48 pm -

1 stop7h 06m

Deal found 9/13

$678

Fri 11/205:09 am -

1 stop5h 40m

Sun 11/295:27 pm -

1 stop6h 27m

Deal found 9/13

$679

Fri 11/205:09 am -

1 stop5h 40m

Sat 11/284:48 pm -

1 stop7h 06m

Deal found 9/13

$721

Best flights from Florence to Syracuse
Discover carefully curated flight deals from Florence to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.

Sat 11/215:09 am -

1 stop5h 45m

Sun 11/295:27 pm -

1 stop6h 27m

Deal found 9/13

$636

Fri 11/205:09 am -

1 stop5h 40m

Sun 11/295:27 pm -

1 stop6h 27m

Deal found 9/13

$679

Sat 11/212:35 pm -

2 stops7h 18m

Sat 11/284:48 pm -

1 stop7h 06m

Deal found 9/13

$759

Fri 11/202:35 pm -

1 stop4h 05m

Sat 11/286:00 am -

2 stops8h 09m

Deal found 9/13

$802

Find flight deals from Florence to Syracuse

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$636 (American Airlines)

Provider with most accurate pricing for Florence-Syracuse Hancock Intl flight deals.

Search Deals

Provider most trusted by Cheapflights users for Florence-Syracuse Hancock Intl flights.

Search Deals

From Florence to Syracuse Hancock Intl

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceSyracuse

FLO Florence - SYR Syracuse Hancock Intl

FLOSYR

Florence

Sat 11/21

5:09 am-10:54 am

1 stop5h 45m

Syracuse Hancock Intl

Sun 11/29

5:27 pm-11:54 pm

1 stop6h 27m

$636

Quickest round-trip

FlorenceSyracuse

FLO Florence - SYR Syracuse Hancock Intl

FLOSYR

Florence

Fri 11/20

5:09 am-10:49 am

1 stop5h 40m

Syracuse Hancock Intl

Sun 11/29

5:27 pm-11:54 pm

1 stop6h 27m

$679

FlorenceSyracuse

FLO Florence - SYR Syracuse Hancock Intl

FLOSYR

Florence

Sat 11/21

2:35 pm-9:53 pm

2 stops7h 18m

Syracuse Hancock Intl

Sat 11/28

4:48 pm-11:54 pm

1 stop7h 06m

$759

FlorenceSyracuse

FLO Florence - SYR Syracuse Hancock Intl

FLOSYR

Florence

Fri 11/20

2:35 pm-6:40 pm

1 stop4h 05m

Syracuse Hancock Intl

Sat 11/28

6:00 am-2:09 pm

2 stops8h 09m

$802

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Sorted by cheapest first

Compare providers for flights from Florence to Syracuse

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Syracuse in September.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
Expedia	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Florence, South Carolina-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Syracuse flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Florence, South Carolina-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Florence with our price prediction graph.

FLO-SYR

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Florence, South Carolina to Syracuse?
There are many flights that can get you from Florence, South Carolina to Syracuse in 5h 45m. Fly via American Airlines to get the fastest option. There are 646 mi between Florence, South Carolina and Syracuse.
Can I find deals for flights from Florence to Syracuse that include hotel bookings?
Yes. In addition to deals on Florence to Syracuse flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Florence to Syracuse?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Syracuse.
Can I find deals for business class flights from Florence to Syracuse?
Yes. Cheapflights offers flight deals from Florence to Syracuse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$636+ Cheap flights from Florence, SC to Syracuse (FLO - SYR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Florence to Syracuse with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Florence to Syracuse

Cheapest flights from Florence to SyracuseExplore the most affordable flight options available from Florence to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.

Explore the most affordable flight options available from Florence to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.

Best flights from Florence to SyracuseDiscover carefully curated flight deals from Florence to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.

Discover carefully curated flight deals from Florence to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.

Find flight deals from Florence to Syracuse

Most accurate provider

Most trusted provider

Round-trip from

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Use the filters below to find and compare flights from Florence to Syracuse that are best for you.

Compare providers for flights from Florence to Syracuse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Syracuse in September.

Best time to book a flight from Florence to Syracuse

Have a flexible travel schedule? Discover the best time to fly to Syracuse from Florence with our price prediction graph.

Related info for your journey

How long is the flight from Florence, South Carolina to Syracuse?

Can I find deals for flights from Florence to Syracuse that include hotel bookings?

How can I find direct flights from Florence to Syracuse?

Can I find deals for business class flights from Florence to Syracuse?

Traveling to a place near Syracuse?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Florence to Syracuse

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Complete your trip

Complete your trip to Syracuse by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Florence to Syracuse by cabin class

Find flights from Florence to Syracuse, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Florence and Syracuse flights

Browse other Florence and Syracuse flight options. Last updated on September 15, 2026.

Other flights from Florence

Browse through other flights departing from Florence. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.

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Cheapest flights from Florence to Syracuse
Explore the most affordable flight options available from Florence to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.

Best flights from Florence to Syracuse
Discover carefully curated flight deals from Florence to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.