$138+ Cheap flights from Myrtle Beach to Buffalo (MYR - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — BUF
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Buffalo
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Cheapest flights from Myrtle Beach to BuffaloExplore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Myrtle Beach to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:58 pm -
1 stop4h 54m
Wed 9/306:05 am -
1 stop4h 02m
Deal found 9/8![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:25 pm -
1 stop6h 30m
Tue 12/2212:40 pm -
2 stops8h 00m
Deal found 9/10![Southwest logo]()
$326
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:29 pm -
1 stop5h 07m
Tue 11/105:13 am -
1 stop6h 29m
Deal found 9/8![American Airlines logo]()
$327
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops11h 55m
Tue 11/38:25 am -
2 stops10h 55m
Deal found 9/8![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:35 pm -
1 stop4h 10m
Tue 11/1012:45 pm -
2 stops6h 35m
Deal found 9/8![Southwest logo]()
$332
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:13 am -
1 stop3h 52m
Tue 10/64:24 pm -
1 stop5h 02m
Deal found 9/6![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/161:29 pm -
1 stop5h 07m
Thu 12/316:00 am -
1 stop5h 39m
Deal found 9/8![American Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:40 pm -
1 stop3h 45m
Tue 10/276:15 am -
2 stops11h 45m
Deal found 9/6![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:23 pm -
1 stop5h 34m
Wed 10/73:56 pm -
1 stop6h 06m
Deal found 9/9![American Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:22 am -
1 stop5h 44m
Tue 11/312:58 pm -
1 stop3h 25m
Deal found 9/6![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:00 pm -
1 stop3h 59m
Sun 10/255:50 am -
1 stop5h 11m
Deal found 9/9![American Airlines logo]()
$354
Best flights from Myrtle Beach to BuffaloDiscover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Myrtle Beach to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:25 pm -
1 stop6h 30m
Tue 12/2212:40 pm -
2 stops8h 00m
Deal found 9/10![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:54 pm -
1 stop5h 05m
Wed 11/1110:51 am -
1 stop6h 20m
Deal found 9/7![United Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:25 pm -
2 stops9h 45m
Tue 11/38:25 am -
2 stops10h 55m
Deal found 9/6![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:40 pm -
1 stop10h 05m
Fri 11/276:00 am -
1 stop4h 05m
Deal found 9/9![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:23 am -
1 stop4h 00m
Sun 9/276:00 am -
2 stops9h 16m
Deal found 9/6![United Airlines logo]()
$552
Last-minute flights from Myrtle Beach to BuffaloDiscover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Buffalo. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:58 pm -
1 stop4h 54m
Wed 9/306:05 am -
1 stop4h 02m
Deal found 9/8![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:45 pm -
1 stop4h 02m
Mon 10/125:50 am -
1 stop5h 11m
Deal found 9/7![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:23 pm -
1 stop5h 34m
Wed 10/73:56 pm -
1 stop6h 06m
Deal found 9/9![American Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:13 am -
1 stop3h 52m
Tue 10/64:24 pm -
1 stop5h 02m
Deal found 9/6![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:00 pm -
1 stop3h 59m
Mon 10/125:50 am -
1 stop5h 11m
Deal found 9/6![American Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:40 pm -
1 stop3h 45m
Tue 10/276:15 am -
2 stops11h 45m
Deal found 9/6![Southwest logo]()
$338
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:00 pm -
1 stop3h 59m
Sun 10/255:50 am -
1 stop5h 11m
Deal found 9/9![American Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:22 am -
1 stop5h 44m
Tue 11/312:58 pm -
1 stop3h 25m
Deal found 9/6![American Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:25 pm -
2 stops9h 45m
Tue 11/38:25 am -
2 stops10h 55m
Deal found 9/6![Southwest logo]()
$358
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:25 pm -
2 stops9h 45m
Sun 11/16:00 am -
1 stop4h 05m
Deal found 9/7![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
2 stops11h 55m
Tue 11/38:25 am -
2 stops10h 55m
Deal found 9/8![Southwest logo]()
$331
One-way flights from Myrtle Beach to BuffaloSearch for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Myrtle Beach to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:12 pm -
2 stops43h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$138
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:58 pm -
1 stop5h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$155
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/104:03 pm -
1 stop5h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![American Airlines logo]()
$167
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:25 pm -
1 stop6h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Southwest logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/134:03 pm -
2 stops20h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$177
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1010:38 am -
2 stops8h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:46 pm -
2 stops22h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:25 pm -
1 stop3h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$239
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:30 am -
1 stop4h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![American Airlines logo]()
$249
Find flight deals from Myrtle Beach to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $302 (Kiwi.com) |
One-way from | $138 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $343 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Mon 11/16
6:12 pm-1:15 pm
2 stops43h 03m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Tue 10/13
6:58 pm-11:59 pm
1 stop5h 01m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Tue 12/15
6:59 pm-12:05 am
1 stop5h 06m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$155
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Mon 11/16
3:25 pm-9:55 pm
1 stop6h 30m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$173
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Sat 10/10
10:38 am-3:10 pm
1 stop4h 32m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$217
Quickest round-trip
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Wed 9/23
2:25 pm-5:45 pm
1 stop3h 20m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Sun 11/8
7:35 pm-11:45 pm
1 stop4h 10m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$239
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Tue 12/15
3:25 pm-9:55 pm
1 stop6h 30m
Buffalo
Tue 12/22
12:40 pm-8:40 pm
2 stops8h 00m
$326
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Fri 10/30
1:25 pm-11:10 pm
2 stops9h 45m
Buffalo
Tue 11/3
8:25 am-7:20 pm
2 stops10h 55m
$358
Myrtle BeachBuffalo
MYR Myrtle Beach Intl - BUF Buffalo
MYRBUF
Myrtle Beach Intl
Fri 11/20
1:40 pm-11:45 pm
1 stop10h 05m
Buffalo
Fri 11/27
6:00 am-10:05 am
1 stop4h 05m
$435
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Buffalo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Myrtle Beach with our price prediction graph.
MYR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Buffalo
What is the cheapest month to book a flight from Myrtle Beach to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Buffalo (average of $290). Flying from Myrtle Beach to Buffalo in July is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to Buffalo?
Airfare is typical for this route at the moment.
Myrtle Beach to Buffalo flights typically cost between $309 and $375 in September.The cheapest round-trip price found within the last 5 days was $309 on Delta (Sep 29-Sep 30).
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 10, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Myrtle Beach to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Crew
8.6
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Myrtle Beach and Buffalo flights
Browse other Myrtle Beach and Buffalo flight options. Last updated on September 10, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Myrtle Beach to Buffalo
Discover the top 2 airlines that operate flights from Myrtle Beach to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$250 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$380 | FlexibilityNo cancel fee | On-time63% |