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$249+ Cheap flights from Reagan-National (DCA) to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
DCA — FLO
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Reagan-National to Florence

Cheapest flights from Reagan-National to Florence
Explore the most affordable flight options available from Reagan-National to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:24 pm
DCA
-
FLO
1 stop6h 33m
American Airlines
Sat 3/216:25 pm
FLO
-
DCA
1 stop5h 34m
American Airlines
Deal found 2/10$269
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:28 pm
DCA
-
FLO
2 stops7h 29m
American Airlines
Sat 3/216:25 pm
FLO
-
DCA
1 stop5h 34m
American Airlines
Deal found 2/10$274
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Fri 3/206:20 pm
FLO
-
DCA
1 stop5h 39m
American Airlines
Deal found 2/10$313
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Fri 3/205:16 am
FLO
-
DCA
1 stop5h 41m
American Airlines
Deal found 2/10$357
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/157:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Sun 2/225:16 am
FLO
-
DCA
1 stop4h 03m
American Airlines
Deal found 2/10$369
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Sun 3/226:20 pm
FLO
-
DCA
1 stop3h 40m
American Airlines
Deal found 2/10$383
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Sun 3/226:20 pm
FLO
-
DCA
1 stop3h 40m
American Airlines
Deal found 2/10$427
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:41 pm
DCA
-
FLO
1 stop4h 16m
American Airlines
Sat 3/215:16 am
FLO
-
DCA
2 stops7h 58m
American Airlines
Deal found 2/10$432

Find flight deals from Reagan-National to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Reagan-National (DCA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$249
(American Airlines)
Provider with most accurate pricing for Washington, D.C. Reagan-National-Florence flight deals.
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Provider most trusted by Cheapflights users for Washington, D.C. Reagan-National-Florence flights.
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From Washington, D.C. Reagan-National to Florence
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One-way flight from Washington, D.C. Reagan-National to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Reagan-National to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Washington, D.C. Reagan-National Airport to Florence that are best for you.

Fly from

Reagan-National

Fly to

Florence

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/16

1:41 pm-5:50 pm

1 stop4h 09m

Florence

Sat 3/21

6:25 pm-11:59 pm

1 stop5h 34m

$269

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/16

5:24 pm-11:57 pm

1 stop6h 33m

Florence

Fri 3/20

5:16 am-10:57 am

1 stop5h 41m

$313

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 3/14

7:41 pm-11:57 pm

1 stop4h 16m

Florence

Fri 3/20

6:20 pm-11:59 pm

1 stop5h 39m

$313

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sun 3/15

7:41 pm-11:57 pm

1 stop4h 16m

Florence

Sat 3/21

6:25 pm-11:59 pm

1 stop5h 34m

$313

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 3/14

7:41 pm-11:57 pm

1 stop4h 16m

Florence

Sat 3/21

5:16 am-10:57 am

1 stop5h 41m

$383

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Mon 3/16

5:24 pm-11:57 pm

1 stop6h 33m

Florence

Sun 3/22

6:20 pm-10:00 pm

1 stop3h 40m

$383

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 3/14

5:24 pm-11:57 pm

1 stop6h 33m

Florence

Sun 3/22

6:20 pm-10:00 pm

1 stop3h 40m

$383

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sun 3/1

5:24 pm-11:57 pm

1 stop6h 33m

$249

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 4/11

11:56 am-11:53 pm

2 stops11h 57m

$373

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Fri 4/10

7:46 pm-11:53 pm

1 stop4h 07m

$446

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 11 results
1
2

Compare providers for flights from Reagan-National to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Reagan-National to Florence in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Washington, D.C. Reagan-National Airport-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Washington, D.C. Reagan-National Airport-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Washington, D.C. Reagan-National Airport-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Washington, D.C. Reagan-National Airport-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Washington, D.C. Reagan-National Airport-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Reagan-National to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Reagan-National with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Washington, D.C. Reagan-National Airport to Florence

What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina?

Currently, June is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina (average of $128). Flying from Washington, D.C. Reagan-National Airport to Florence, South Carolina in March is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Reagan-National to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Washington, D.C. Reagan-National?

    Florence (FLO) is the airport you will fly into if you book a flight from Washington, D.C. Reagan-National to Florence. You should not have trouble finding flights to Florence from Washington, D.C. Reagan-National; the airport handles an average of 0 inbound flights from Washington, D.C. Reagan-National per day. You should also have plenty of airline options to choose from since 0 airlines have flights to the Florence airport from Washington, D.C. Reagan-National. It is only a 2.3 mi journey from Florence (FLO) to Florence’s city center.

  • How long is the flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina?

    A quick flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina can take about 4h 09m. American Airlines provides one of the quickest options available for as low as $269. The distance from Washington, D.C. Reagan-National Airport to Florence, South Carolina is about 355 mi.

  • Can I find deals for flights from Reagan-National to Florence that include hotel bookings?

    Yes. In addition to deals on Reagan-National to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Reagan-National to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reagan-National to Florence.

  • Can I find deals for business class flights from Reagan-National to Florence?

    Yes. Cheapflights offers flight deals from Reagan-National to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina?

    Currently, June is the cheapest month in which you can book a flight from Washington, D.C. Reagan-National Airport to Florence, South Carolina (average of $128). Flying from Washington, D.C. Reagan-National Airport to Florence, South Carolina in March is currently the most expensive (average of $189). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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