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$425+ Cheap flights from Pittsburgh to Florence, SC (PIT - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — FLO
Oct 13 — Oct 201
Mon 10/13
Mon 10/20
1 adult, Economy
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Cheap flight deals from Pittsburgh to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Pittsburgh (PIT) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 13, 2025.

Round-trip from

$425
(American Airlines)
From Pittsburgh to Florence
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Find flight deals from Pittsburgh to Florence

Cheapest flights from Pittsburgh to Florence
Explore the most affordable flight options available from Pittsburgh to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2025.

This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:09 pmPIT - FLO
1 stop4h 54mAmerican Airlines
Tue 10/216:14 amFLO - PIT
2 stops10h 20mAmerican Airlines
Deal found 9/12$425

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 13, 2025.
Use the filters below to find and compare flights from Pittsburgh to Florence that are best for you.

Fly from

Pittsburgh

Fly to

Florence

Route

Depart

Return

Price

PittsburghFlorence

PIT - FLO

PITFLO

Pittsburgh

Fri 10/17

7:09 pm-12:03 am

1 stop4h 54m

Florence

Tue 10/21

6:14 am-4:34 pm

2 stops10h 20m

$425

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Best time to book a flight from Pittsburgh to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to Florence

What is the cheapest month to book a flight from Pittsburgh to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Pittsburgh to Florence, South Carolina (average of $366). Flying from Pittsburgh to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 13, 2025.
Get a feel of what it's like to fly with American Airlines from Pittsburgh to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Entertainment

6.9

Boarding

7.5

Overall

7.2

Food

6.4

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pittsburgh to Florence, South Carolina?

    American Airlines can get you from Pittsburgh to Florence, South Carolina in just under 4h 54m. Your travel time can differ by up to . The distance from Pittsburgh to Florence, South Carolina is about 437 mi.

  • What is the cheapest airline to fly from Pittsburgh to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($367), offers the cheapest pricing from Pittsburgh to Florence, South Carolina.

  • Can I find deals for flights from Pittsburgh to Florence that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to Florence.

  • Can I find deals for business class flights from Pittsburgh to Florence?

    Yes. Cheapflights offers flight deals from Pittsburgh to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Pittsburgh to Florence, South Carolina (average of $366). Flying from Pittsburgh to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Pittsburgh to Florence

Discover the top airline that operate flights from Pittsburgh to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$367Average$554FlexibilityNo cancel feeOn-time71%

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