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Florence

$229+ Cheap flights from Michigan to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — FLO
dic. 3 — dic. 101
mié. 12/3
mié. 12/10
1 adult, Economy
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Find flight deals from Michigan to Florence

Cheapest flights from Michigan to Florence
Explore the most affordable flight options available from Michigan to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 3, 2025.

This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/23:44 pmORD - FLO
1 stop6h 09mAmerican Airlines
mar. 12/96:15 amFLO - ORD
1 stop5h 38mAmerican Airlines
Deal found 11/2$393
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/3010:15 pmORD - FLO
2 stops13h 11mAmerican Airlines
mar. 1/65:36 pmFLO - ORD
2 stops14h 51mAmerican Airlines
Deal found 10/31$444
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/3010:15 pmORD - FLO
2 stops13h 11mAmerican Airlines
vie. 1/21:07 pmFLO - ORD
2 stops9h 07mAmerican Airlines
Deal found 10/31$458
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:00 amORD - FLO
1 stop6h 26mAmerican Airlines
lun. 1/512:51 pmFLO - ORD
1 stop4h 14mAmerican Airlines
Deal found 10/31$463
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/215:00 amORD - FLO
1 stop4h 45mAmerican Airlines
mar. 12/26:15 amFLO - ORD
2 stops10h 31mAmerican Airlines
Deal found 10/31$464
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/255:00 amORD - FLO
1 stop6h 26mAmerican Airlines
vie. 1/21:07 pmFLO - ORD
2 stops9h 07mAmerican Airlines
Deal found 10/31$468
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/239:34 amORD - FLO
2 stops7h 33mAmerican Airlines
mié. 12/36:15 amFLO - ORD
2 stops12h 16mAmerican Airlines
Deal found 10/31$469
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/216:35 pmORD - FLO
1 stop4h 06mAmerican Airlines
jue. 12/45:15 amFLO - ORD
1 stop4h 53mAmerican Airlines
Deal found 10/31$474
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/238:02 amORD - FLO
2 stops9h 05mAmerican Airlines
jue. 12/411:16 amFLO - ORD
1 stop5h 54mAmerican Airlines
Deal found 10/31$479

Cheap flight deals from Michigan to Florence

Keep the following information in mind while searching for Michigan to Florence flight deals. Data was last updated noviembre 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$393
(American Airlines)

One-way from

$229
(American Airlines)
Provider with most accurate pricing for Detroit (DTT)-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Florence flights.
Search Deals
From Michigan to Florence
Search Deals
One-way flight from Michigan to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
Use the filters below to find and compare flights from Michigan to Florence that are best for you.

Fly from

Michigan

Fly to

Florence

Route

Depart

Return

Price

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

mar. 12/2

3:44 pm-10:53 pm

1 stop6h 09m

Florence

mar. 12/9

6:15 am-10:53 am

1 stop5h 38m

$393

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

mar. 12/30

10:15 pm-12:26 pm

2 stops13h 11m

Florence

jue. 1/1

5:15 am-9:21 am

1 stop5h 06m

$453

LansingFlorence

LAN - FLO

LANFLO

Lansing Capital City

sáb. 3/14

7:04 am-2:05 pm

2 stops7h 01m

Florence

mar. 3/17

2:30 pm-10:28 pm

2 stops7h 58m

$457

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

dom. 12/28

7:11 am-12:42 pm

1 stop4h 31m

Florence

mar. 1/6

6:15 am-11:35 am

1 stop6h 20m

$463

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

jue. 12/25

5:00 am-12:26 pm

1 stop6h 26m

Florence

lun. 1/5

12:51 pm-4:05 pm

1 stop4h 14m

$463

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

mié. 12/31

5:00 am-12:26 pm

1 stop6h 26m

Florence

lun. 1/5

12:51 pm-4:05 pm

1 stop4h 14m

$463

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

dom. 11/23

5:34 pm-11:41 pm

1 stop5h 07m

Florence

mar. 12/2

6:15 am-6:21 pm

2 stops13h 06m

$464

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

sáb. 12/27

5:28 pm-12:15 am

1 stop5h 47m

Florence

vie. 1/2

1:07 pm-9:14 pm

2 stops9h 07m

$468

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

jue. 12/25

5:00 am-12:26 pm

1 stop6h 26m

Florence

vie. 1/2

1:07 pm-9:14 pm

2 stops9h 07m

$468

ChicagoFlorence

ORD - FLO

ORDFLO

Chicago O'Hare Intl

sáb. 11/22

6:35 pm-11:41 pm

1 stop4h 06m

Florence

jue. 12/4

6:31 pm-11:46 pm

1 stop6h 15m

$474

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 18 results
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Best time to book a flight from Michigan to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Florence

What is the cheapest month to book a flight from Michigan to Florence, South Carolina?

Currently, August is the cheapest month in which you can book a flight from Michigan to Florence, South Carolina (average of $78). Flying from Michigan to Florence, South Carolina in January is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Michigan?

    If you book a flight to Florence from Michigan, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • How long is the flight from Michigan to Florence, South Carolina?

    For as low as $393, American Airlines can have you in Florence, South Carolina from Michigan in 6h 09m. Michigan and Florence, South Carolina are separated by a distance of 697 mi.

  • What are the most popular routes from Michigan to Florence, South Carolina?

    While some choose either Chicago O'Hare Intl - Florence or Detroit Metropolitan Wayne County - Florence, Grand Rapids Gerald R. Ford Intl - Florence is the most popular route from Michigan to Florence, South Carolina.

  • Can I find deals for flights from Michigan to Florence that include hotel bookings?

    Yes. In addition to deals on Michigan to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Florence.

  • Can I find deals for business class flights from Michigan to Florence?

    Yes. Cheapflights offers flight deals from Michigan to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to Florence, South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Michigan to Florence, South Carolina (average of $78). Flying from Michigan to Florence, South Carolina in January is currently the most expensive (average of $159). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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