$286+ Cheap flights from Florence, SC (FLO) to Michigan
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Aug 25 — Sep 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Florence to Michigan with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Michigan
Cheapest
Best
Last-minute
One-way
Cheapest flights from Florence to MichiganExplore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 26, 2026.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:22 am
FLO
- ORD
1 stop6h 53m
American Airlines
Wed 8/266:49 am
ORD
- FLO
1 stop7h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:22 am
FLO
- ORD
1 stop5h 29m
American Airlines
Mon 8/315:49 pm
ORD
- FLO
1 stop4h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$441
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Sun 8/97:30 am
ORD
- FLO
1 stop5h 42m
American Airlines
Deal found 7/21![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Fri 8/216:49 am
ORD
- FLO
1 stop7h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Mon 8/104:53 pm
ORD
- FLO
1 stop5h 06m
American Airlines
Deal found 7/22![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:22 pm
FLO
- DTW
1 stop7h 08m
American Airlines
Wed 8/126:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/23![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:22 pm
FLO
- DTW
1 stop7h 08m
American Airlines
Mon 9/76:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/25![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 am
FLO
- DTW
1 stop5h 13m
American Airlines
Sun 8/167:54 pm
DTW
- FLO
1 stop4h 04m
American Airlines
Deal found 7/22![American Airlines logo]()
$649
Best flights from Florence to MichiganDiscover carefully curated flight deals from Florence to Michigan that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
Discover carefully curated flight deals from Florence to Michigan that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 26, 2026.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:22 am
FLO
- ORD
1 stop5h 29m
American Airlines
Mon 8/315:49 pm
ORD
- FLO
1 stop4h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$441
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Sun 8/97:30 am
ORD
- FLO
1 stop5h 42m
American Airlines
Deal found 7/21![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Fri 8/216:49 am
ORD
- FLO
1 stop7h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:22 pm
FLO
- DTW
1 stop7h 08m
American Airlines
Wed 8/126:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/23![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:22 pm
FLO
- DTW
1 stop6h 35m
American Airlines
Mon 9/76:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/25![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:22 pm
FLO
- DTW
1 stop7h 08m
American Airlines
Mon 9/76:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/25![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 am
FLO
- DTW
1 stop5h 13m
American Airlines
Sun 8/167:54 pm
DTW
- FLO
1 stop4h 04m
American Airlines
Deal found 7/22![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:22 am
FLO
- ORD
2 stops7h 32m
American Airlines
Wed 8/262:59 pm
ORD
- FLO
2 stops7h 00m
American Airlines
Deal found 7/21![American Airlines logo]()
$788
Last-minute flights from Florence to MichiganDiscover last-minute flight deals from Florence to Michigan. Data last updated July 26, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Michigan. Data last updated July 26, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Sun 8/97:30 am
ORD
- FLO
1 stop5h 42m
American Airlines
Deal found 7/21![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Mon 8/104:53 pm
ORD
- FLO
1 stop5h 06m
American Airlines
Deal found 7/22![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 am
FLO
- DTW
1 stop5h 13m
American Airlines
Sun 8/167:54 pm
DTW
- FLO
1 stop4h 04m
American Airlines
Deal found 7/22![American Airlines logo]()
$649
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:22 pm
FLO
- DTW
1 stop7h 08m
American Airlines
Wed 8/126:43 pm
DTW
- FLO
1 stop4h 16m
American Airlines
Deal found 7/23![American Airlines logo]()
$551
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:22 pm
FLO
- ORD
1 stop7h 35m
American Airlines
Fri 8/216:49 am
ORD
- FLO
1 stop7h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$537
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:22 am
FLO
- ORD
1 stop6h 53m
American Airlines
Wed 8/266:49 am
ORD
- FLO
1 stop7h 07m
American Airlines
Deal found 7/21![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:22 am
FLO
- ORD
1 stop5h 29m
American Airlines
Mon 8/315:49 pm
ORD
- FLO
1 stop4h 10m
American Airlines
Deal found 7/21![American Airlines logo]()
$441
One-way flights from Florence to MichiganSearch for one-way flight options from Florence to Michigan. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
Search for one-way flight options from Florence to Michigan. Find affordable one-way fares based on user searches. Data last updated July 26, 2026.
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:43 pm
FLO
- DTW
1 stop3h 47m
American Airlines
Deal found 7/22![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:22 am
FLO
- DTW
2 stops13h 58m
American Airlines
Deal found 7/21![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:43 pm
FLO
- DTW
2 stops19h 01m
American Airlines
Deal found 7/22![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:09 am
FLO
- DTW
2 stops11h 00m
American Airlines
Deal found 7/25![American Airlines logo]()
$445
Find flight deals from Florence to Michigan
Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated July 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $345 (American Airlines) |
One-way from | $286 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 26, 2026.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceChicago
FLO - ORD
FLOORD
Florence
Fri 8/28
6:22 am-10:51 am
1 stop5h 29m
Chicago O'Hare Intl
Mon 8/31
5:49 pm-10:59 pm
1 stop4h 10m
$441
FlorenceChicago
FLO - ORD
FLOORD
Florence
Wed 8/5
3:22 pm-9:57 pm
1 stop7h 35m
Chicago O'Hare Intl
Sun 8/9
7:30 am-2:12 pm
1 stop5h 42m
$488
FlorenceChicago
FLO - ORD
FLOORD
Florence
Fri 8/14
3:22 pm-9:57 pm
1 stop7h 35m
Chicago O'Hare Intl
Fri 8/21
6:49 am-2:56 pm
1 stop7h 07m
$537
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Sat 8/8
3:22 pm-10:30 pm
1 stop7h 08m
Detroit Metropolitan Wayne County
Wed 8/12
6:43 pm-10:59 pm
1 stop4h 16m
$551
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Fri 9/4
3:22 pm-9:57 pm
1 stop6h 35m
Detroit Metropolitan Wayne County
Mon 9/7
6:43 pm-10:59 pm
1 stop4h 16m
$567
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Thu 9/3
3:22 pm-10:30 pm
1 stop7h 08m
Detroit Metropolitan Wayne County
Mon 9/7
6:43 pm-10:59 pm
1 stop4h 16m
$567
Quickest round-trip
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Fri 8/7
6:22 am-11:35 am
1 stop5h 13m
Detroit Metropolitan Wayne County
Sun 8/16
7:54 pm-11:58 pm
1 stop4h 04m
$649
FlorenceChicago
FLO - ORD
FLOORD
Florence
Thu 8/20
6:22 am-12:54 pm
2 stops7h 32m
Chicago O'Hare Intl
Wed 8/26
2:59 pm-10:59 pm
2 stops7h 00m
$788
Cheapest one-way
Quickest one-way
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Thu 9/10
1:43 pm-5:30 pm
1 stop3h 47m
$286
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Tue 8/18
6:22 am-8:20 pm
2 stops13h 58m
$324
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Florence to Michigan
Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
FLO-DTW
FLO-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Michigan
FLO-USMI
FLO-DTW
FLO-ORD
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Florence to Michigan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations