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$319+ Cheap flights from Massachusetts to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — FLO
Mar 3 — Mar 101
Tue 3/3
Tue 3/10
1 adult, Economy
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Cheap flight deals from Massachusetts to Florence

Cheapest flights from Massachusetts to Florence
Explore the most affordable flight options available from Massachusetts to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 1, 2026.

This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:30 pm
BOS
-
FLO
1 stop5h 38m
American Airlines
Wed 3/46:15 am
FLO
-
BOS
1 stop6h 48m
American Airlines
Deal found 1/30$319
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/412:21 pm
BOS
-
FLO
1 stop4h 48m
American Airlines
Mon 2/95:36 pm
FLO
-
BOS
1 stop4h 46m
American Airlines
Deal found 1/31$389
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:23 pm
BOS
-
FLO
1 stop4h 20m
American Airlines
Sun 2/16:15 am
FLO
-
BOS
1 stop4h 16m
American Airlines
Deal found 1/30$419
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:57 am
BOS
-
FLO
1 stop4h 24m
American Airlines
Thu 10/82:17 pm
FLO
-
BOS
1 stop5h 55m
American Airlines
Deal found 1/30$436
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:30 pm
BOS
-
FLO
1 stop6h 27m
American Airlines
Sun 3/295:16 am
FLO
-
BOS
1 stop4h 49m
American Airlines
Deal found 1/31$456
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/144:48 pm
BOS
-
FLO
1 stop7h 08m
American Airlines
Sat 7/182:36 pm
FLO
-
BOS
2 stops8h 06m
American Airlines
Deal found 1/31$458
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/44:14 pm
BDL
-
FLO
1 stop6h 29m
American Airlines
Wed 2/185:58 pm
FLO
-
BDL
1 stop4h 46m
American Airlines
Deal found 1/31$489

Find flight deals from Massachusetts to Florence

Keep the following information in mind while searching for Massachusetts to Florence flight deals. Data was last updated February 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(American Airlines)

Popular in

April

Cheapest in

March

Average price

$471
Provider with most accurate pricing for Boston Logan Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Florence flights.
Search Deals
From Massachusetts to Florence
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
Use the filters below to find and compare flights from Massachusetts to Florence that are best for you.

Fly from

Massachusetts

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 2/18

5:30 pm-11:08 pm

1 stop5h 38m

Florence

Wed 3/4

6:15 am-1:03 pm

1 stop6h 48m

$319

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$319

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Fri 3/13

10:56 am-5:50 pm

1 stop6h 54m

Florence

Fri 3/20

5:16 am-10:05 am

1 stop4h 49m

$389

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Fri 3/27

5:30 pm-11:57 pm

1 stop6h 27m

Florence

Sun 3/29

5:16 am-10:05 am

1 stop4h 49m

$456

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 7/14

4:48 pm-11:56 pm

1 stop7h 08m

Florence

Sat 7/18

2:36 pm-10:42 pm

2 stops8h 06m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Best time to book a flight from Massachusetts to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Florence

What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

Currently, March is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $63). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Massachusetts?

    For a flight from Massachusetts to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Massachusetts to Florence, South Carolina?

    A quick flight from Massachusetts to Florence, South Carolina can take about 5h 38m. American Airlines provides one of the quickest options available for as low as $319. The distance between Massachusetts and Florence, South Carolina is about 735 mi.

  • What are the most popular routes from Massachusetts to Florence, South Carolina?

    The most popular flight routes from Massachusetts to Florence, South Carolina are Boston Logan Intl - Florence, Hartford Bradley Intl - Florence and Albany Intl - Florence.

  • Can I find deals for flights from Massachusetts to Florence that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Florence.

  • Can I find deals for business class flights from Massachusetts to Florence?

    Yes. Cheapflights offers flight deals from Massachusetts to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $63). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Alternative routes for Massachusetts to Florence

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Massachusetts to Florence

Discover the top airline that operate flights from Massachusetts to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$279Average$454FlexibilityNo cancel feeOn-time71%

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