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Florence

$316+ Cheap flights from Massachusetts to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — FLO
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Massachusetts to Florence

Keep the following information in mind while searching for Massachusetts to Florence flight deals. Data was last updated September 15, 2025.

Round-trip from

$316
(American Airlines)

Popular in

February

Cheapest in

January

Average price

$446
From Massachusetts to Florence
Search Deals
High demand for flights, 6% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Massachusetts to Florence

Cheapest flights from Massachusetts to Florence
Explore the most affordable flight options available from Massachusetts to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:01 amBOS - FLO
2 stops11h 52mAmerican Airlines
Sat 11/1511:11 amFLO - BOS
2 stops8h 49mAmerican Airlines
Deal found 9/13$316
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:24 pmORH - FLO
2 stops6h 52mAmerican Airlines
Tue 9/306:14 amFLO - ORH
2 stops9h 45mAmerican Airlines
Deal found 9/14$429
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:32 amBOS - FLO
1 stop6h 32mAmerican Airlines
Mon 10/2011:11 amFLO - BOS
1 stop4h 36mAmerican Airlines
Deal found 9/14$439
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:24 pmORH - FLO
2 stops24h 48mAmerican Airlines
Sat 9/275:37 pmFLO - ORH
2 stops22h 21mAmerican Airlines
Deal found 9/14$445
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:24 pmORH - FLO
2 stops6h 52mAmerican Airlines
Sun 9/284:57 pmFLO - ORH
2 stops22h 59mAmerican Airlines
Deal found 9/14$454
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:23 pmORH - FLO
2 stops24h 49mAmerican Airlines
Sat 9/275:37 pmFLO - ORH
2 stops22h 21mAmerican Airlines
Deal found 9/14$470
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:23 pmORH - FLO
2 stops24h 49mAmerican Airlines
Sun 9/284:57 pmFLO - ORH
2 stops22h 59mAmerican Airlines
Deal found 9/14$479
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/198:22 amBDL - FLO
1 stop5h 42mAmerican Airlines
Sun 10/262:29 pmFLO - BDL
1 stop5h 56mAmerican Airlines
Deal found 9/13$481
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:23 pmORH - FLO
2 stops6h 53mAmerican Airlines
Sat 9/275:37 pmFLO - ORH
2 stops22h 21mAmerican Airlines
Deal found 9/14$487
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/214:23 pmORH - FLO
2 stops19h 39mAmerican Airlines
Tue 9/306:14 amFLO - ORH
2 stops9h 45mAmerican Airlines
Deal found 9/14$493
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:06 pmBDL - FLO
1 stop7h 10mAmerican Airlines
Sat 9/276:14 amFLO - BDL
1 stop4h 37mAmerican Airlines
Deal found 9/14$499
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/234:08 pmBDL - FLO
2 stops7h 08mAmerican Airlines
Tue 9/305:37 pmFLO - BDL
1 stop5h 52mAmerican Airlines
Deal found 9/14$504

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Massachusetts to Florence that are best for you.

Fly from

Massachusetts

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Tue 11/11

9:00 pm-9:54 am

2 stops12h 54m

Florence

Sat 11/15

11:11 am-8:00 pm

2 stops8h 49m

$316

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 10/16

7:32 am-2:04 pm

1 stop6h 32m

Florence

Mon 10/20

11:11 am-3:47 pm

1 stop4h 36m

$439

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Fri 9/26

4:23 pm-11:16 pm

2 stops30h 53m

Florence

Tue 9/30

6:14 am-3:59 pm

2 stops9h 45m

$454

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Sat 9/27

4:24 pm-10:53 am

2 stops18h 29m

Florence

Sun 9/28

4:57 pm-3:56 pm

2 stops22h 59m

$454

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Sat 9/27

4:24 pm-4:32 pm

2 stops24h 08m

Florence

Mon 9/29

5:37 pm-3:59 pm

2 stops22h 22m

$454

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Thu 9/25

4:23 pm-12:02 pm

2 stops19h 39m

Florence

Tue 9/30

5:37 pm-3:59 pm

2 stops22h 22m

$454

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Thu 9/25

4:23 pm-12:13 am

2 stops7h 50m

Florence

Sat 9/27

6:14 am-3:58 pm

2 stops33h 44m

$470

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Thu 9/25

4:23 pm-12:13 am

2 stops7h 50m

Florence

Sun 9/28

11:18 am-3:56 pm

2 stops28h 38m

$479

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Fri 9/26

4:23 pm-5:12 pm

2 stops24h 49m

Florence

Sun 9/28

4:57 pm-3:56 pm

2 stops22h 59m

$479

WorcesterFlorence

ORH - FLO

ORHFLO

Worcester

Fri 9/26

4:23 pm-5:12 pm

2 stops24h 49m

Florence

Mon 9/29

5:37 pm-3:59 pm

2 stops22h 22m

$479

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 20 results
1
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Best time to book a flight from Massachusetts to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Florence

What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $366). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to FLO?

Find hourly flight availability from Massachusetts to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Massachusetts to Florence, South Carolina as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Massachusetts?

    For a flight from Massachusetts to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Massachusetts to Florence, South Carolina?

    A quick flight from Massachusetts to Florence, South Carolina can take about 12h 54m. American Airlines provides one of the quickest options available for as low as $316. The distance between Massachusetts and Florence, South Carolina is about 735 mi.

  • What are the most popular routes from Massachusetts to Florence, South Carolina?

    The most popular flight routes from Massachusetts to Florence, South Carolina are Boston Logan Intl - Florence, Hartford Bradley Intl - Florence and Worcester - Florence.

  • Can I find deals for flights from Massachusetts to Florence that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Florence.

  • Can I find deals for business class flights from Massachusetts to Florence?

    Yes. Cheapflights offers flight deals from Massachusetts to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Massachusetts to Florence, South Carolina (average of $366). Flying from Massachusetts to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Alternative routes for Massachusetts to Florence

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Massachusetts to Florence

Discover the top airline that operate flights from Massachusetts to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$311Average$475FlexibilityNo cancel feeOn-time71%

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