$110+ Cheap flights from Massachusetts to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — CHS
Dec 12 — Dec 191
Round-trip
1 adult, Economy
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Find cheap flights from Massachusetts to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Massachusetts to South Carolina
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Cheapest flights from Massachusetts to South CarolinaExplore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
Explore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:30 pm -
1 stop4h 50m
Sun 12/207:15 pm -
1 stop3h 40m
Deal found 11/10![Southwest logo]()
$214
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:25 pm -
1 stop5h 00m
Sat 12/125:55 pm -
1 stop4h 05m
Deal found 11/9![Southwest logo]()
$219
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:30 am -
2 stops8h 04m
Tue 12/224:02 pm -
1 stop6h 48m
Deal found 11/8![United Airlines logo]()
$224
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:41 pm -
1 stop5h 17m
Fri 12/182:25 pm -
1 stop6h 54m
Deal found 11/11![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop4h 50m
Sun 12/136:00 am -
1 stop4h 20m
Deal found 11/9![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:39 pm -
1 stop7h 23m
Thu 12/1712:48 pm -
1 stop3h 46m
Deal found 11/10![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:10 am -
1 stop6h 29m
Tue 12/156:57 am -
1 stop4h 03m
Deal found 11/11![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:02 am -
1 stop5h 15m
Wed 12/96:12 am -
1 stop6h 23m
Deal found 11/9![American Airlines logo]()
$281
This JetBlue deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:40 am -
Nonstop2h 40m
Tue 1/1212:46 pm -
1 stop4h 18m
Deal found 11/10![JetBlue logo]()
$281
This JetBlue deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:35 am -
Nonstop2h 41m
Fri 1/812:46 pm -
1 stop7h 06m
Deal found 11/9![JetBlue logo]()
$283
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:30 am -
2 stops8h 04m
Wed 12/1611:30 am -
1 stop7h 15m
Deal found 11/11![United Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:45 am -
2 stops9h 36m
Fri 1/1511:27 am -
2 stops7h 41m
Deal found 11/9![United Airlines logo]()
$289
Best flights from Massachusetts to South CarolinaDiscover carefully curated flight deals from Massachusetts to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
Discover carefully curated flight deals from Massachusetts to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
1 stop7h 46m
Mon 1/113:23 pm -
1 stop4h 27m
Deal found 11/11![United Airlines logo]()
$229
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2812:58 pm -
Nonstop2h 49m
Mon 2/14:42 pm -
Nonstop2h 22m
Deal found 11/7![Delta logo]()
$244
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1711:45 am -
2 stops8h 35m
Sun 12/207:15 pm -
1 stop3h 40m
Deal found 11/10![Southwest logo]()
$299
This JetBlue deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:14 am -
1 stop4h 39m
Fri 12/181:40 pm -
Nonstop2h 19m
Deal found 11/9![JetBlue logo]()
$350
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:46 pm -
1 stop18h 05m
Sun 11/298:28 pm -
2 stops20h 53m
Deal found 11/10![American Airlines logo]()
$384
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/51:55 pm -
1 stop7h 10m
Sat 5/85:10 pm -
1 stop5h 16m
Deal found 11/11![Delta logo]()
$291
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:10 am -
2 stops10h 15m
Wed 12/168:10 am -
1 stop4h 10m
Deal found 11/11![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:00 am -
2 stops9h 13m
Sat 2/69:46 am -
2 stops10h 04m
Deal found 11/12![United Airlines logo]()
$339
This JetBlue deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/228:59 pm -
Nonstop2h 41m
Tue 12/298:30 am -
1 stop5h 49m
Deal found 11/10![JetBlue logo]()
$376
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/22:58 pm -
1 stop6h 01m
Sat 12/127:48 pm -
1 stop4h 11m
Deal found 11/8![United Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:25 am -
1 stop4h 30m
Sun 12/138:20 am -
2 stops10h 30m
Deal found 11/11![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:10 am -
1 stop5h 31m
Sun 12/137:50 pm -
1 stop5h 20m
Deal found 11/10![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:46 pm -
2 stops28h 19m
Fri 11/276:30 am -
2 stops12h 10m
Deal found 11/8![American Airlines logo]()
$389
This JetBlue deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:45 pm -
1 stop7h 37m
Fri 12/181:40 pm -
Nonstop2h 19m
Deal found 11/9![JetBlue logo]()
$380
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:00 pm -
2 stops9h 11m
Mon 12/72:29 pm -
1 stop7h 24m
Deal found 11/10![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/194:30 pm -
1 stop4h 55m
Mon 3/225:40 am -
2 stops10h 07m
Deal found 11/10![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:10 am -
2 stops10h 15m
Tue 12/227:15 pm -
1 stop4h 40m
Deal found 11/8![Southwest logo]()
$361
This Expedia deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:05 am -
1 stop5h 19m
Sat 11/288:30 am -
1 stop7h 10m
Deal found 11/9![Multiple Airlines logo]()
$949
This Southwest deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:30 am -
1 stop4h 50m
Tue 12/1511:00 am -
2 stops10h 45m
Deal found 11/11![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:45 am -
2 stops9h 36m
Mon 1/44:02 pm -
1 stop6h 48m
Deal found 11/8![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/108:13 am -
2 stops9h 17m
Mon 3/153:34 pm -
1 stop6h 38m
Deal found 11/11![American Airlines logo]()
$460
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:15 am -
Nonstop2h 40m
Sun 12/66:59 pm -
1 stop6h 11m
Deal found 11/10![Delta logo]()
$407
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:30 am -
1 stop6h 02m
Wed 12/910:22 am -
2 stops8h 50m
Deal found 11/9![United Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:26 pm -
1 stop7h 29m
Fri 12/182:35 pm -
1 stop6h 20m
Deal found 11/9![American Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/411:00 am -
1 stop6h 14m
Sun 3/75:40 am -
1 stop4h 23m
Deal found 11/11![Delta logo]()
$422
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops11h 09m
Tue 12/156:15 am -
1 stop6h 28m
Deal found 11/7![United Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:20 am -
1 stop7h 05m
Tue 12/297:15 pm -
1 stop3h 40m
Deal found 11/9![Southwest logo]()
$444
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:04 pm -
1 stop15h 25m
Sun 12/67:55 am -
1 stop10h 43m
Deal found 11/7![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/245:45 am -
2 stops8h 04m
Wed 3/310:19 am -
2 stops8h 30m
Deal found 11/10![United Airlines logo]()
$397
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:15 am -
Nonstop2h 40m
Sun 12/66:19 am -
1 stop6h 14m
Deal found 11/9![Delta logo]()
$437
Last-minute flights from Massachusetts to South CarolinaDiscover last-minute flight deals from Massachusetts to South Carolina. Data last updated November 12, 2026 and is based on user searches.
Discover last-minute flight deals from Massachusetts to South Carolina. Data last updated November 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:02 am -
1 stop5h 15m
Wed 12/96:12 am -
1 stop6h 23m
Deal found 11/9![American Airlines logo]()
$281
This JetBlue deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:35 am -
Nonstop2h 41m
Fri 1/812:46 pm -
1 stop7h 06m
Deal found 11/9![JetBlue logo]()
$283
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:10 am -
1 stop6h 29m
Tue 12/156:57 am -
1 stop4h 03m
Deal found 11/11![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:30 am -
2 stops8h 04m
Wed 12/1611:30 am -
1 stop7h 15m
Deal found 11/11![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:25 pm -
1 stop5h 00m
Sat 12/125:55 pm -
1 stop4h 05m
Deal found 11/9![Southwest logo]()
$219
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop4h 50m
Sun 12/136:00 am -
1 stop4h 20m
Deal found 11/9![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:39 pm -
1 stop7h 23m
Thu 12/1712:48 pm -
1 stop3h 46m
Deal found 11/10![American Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:42 pm -
1 stop7h 16m
Mon 12/146:47 pm -
1 stop4h 12m
Deal found 11/11![American Airlines logo]()
$229
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/159:30 am -
2 stops8h 04m
Tue 12/224:02 pm -
1 stop6h 48m
Deal found 11/8![United Airlines logo]()
$224
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/173:30 pm -
1 stop4h 50m
Sun 12/207:15 pm -
1 stop3h 40m
Deal found 11/10![Southwest logo]()
$214
This JetBlue deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:40 am -
Nonstop2h 40m
Tue 1/512:46 pm -
1 stop7h 06m
Deal found 11/10![JetBlue logo]()
$281
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:45 am -
2 stops9h 36m
Fri 1/1511:27 am -
2 stops7h 41m
Deal found 11/9![United Airlines logo]()
$289
One-way flights from Massachusetts to South CarolinaSearch for one-way flight options from Massachusetts to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
Search for one-way flight options from Massachusetts to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/3111:20 am -
1 stop7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Southwest logo]()
$110
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:41 pm -
1 stop5h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![American Airlines logo]()
$115
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/25:45 am -
2 stops9h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$148
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:00 am -
1 stop4h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![American Airlines logo]()
$149
This deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:00 am -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$160
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/89:30 am -
2 stops8h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$165
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:34 pm -
1 stop5h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![American Airlines logo]()
$167
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:17 am -
1 stop4h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:29 am -
1 stop21h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Multiple Airlines logo]()
$173
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/151:06 pm -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$174
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:30 am -
2 stops8h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$177
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 pm -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$177
Find flight deals from Massachusetts to South Carolina
Keep the following information in mind while searching for Massachusetts to South Carolina flight deals. Data was last updated November 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (Delta) |
One-way from | $110 (Southwest) |
Popular in | October |
Cheapest in | January |
Average price | $355 |
Good round-trip deal | $238 or less |
Good one-way deal | $221 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Massachusetts to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
Use the filters below to find and compare flights from Massachusetts to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Tue 12/15
5:30 am-10:05 am
1 stop4h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$110
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Fri 1/1
5:45 am-3:21 pm
2 stops9h 36m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$115
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Sat 1/2
5:45 am-3:21 pm
2 stops9h 36m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 2/27
4:50 pm-10:21 pm
1 stop5h 31m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
Quickest round-trip
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Fri 1/29
12:58 pm-3:47 pm
Nonstop2h 49m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Wed 12/9
11:20 am-7:25 pm
2 stops8h 05m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Sat 1/16
5:10 am-7:35 pm
2 stops14h 25m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$193
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Wed 2/24
7:25 am-4:45 pm
2 stops9h 20m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$194
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Fri 12/25
6:00 am-10:38 am
1 stop4h 38m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Mon 1/25
7:11 am-11:27 am
1 stop4h 16m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Massachusetts to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Massachusetts with our price prediction graph.
BOS-MYR
BOS-GSP
BOS-CHS
HYA-CHS
BOS-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Massachusetts to South Carolina
USMA-USSC
BOS-MYR
BOS-GSP
BOS-CHS
HYA-CHS
What is the cheapest month to book a flight from Massachusetts to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Massachusetts to South Carolina (average of $241). Flying from Massachusetts to South Carolina in October is currently the most expensive (average of $420). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MA to SC?
Find hourly flight availability from Massachusetts to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2026.
It’s optimal to fly from Massachusetts to South Carolina in the evening. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight at noon.
Weekly flight availability from Massachusetts to South Carolina
Explore weekly flight availability from Massachusetts to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 12, 2026.
The most flights from USMA to USSC are scheduled on a Tuesday (6 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Massachusetts to South Carolina?
Airfare is below average for this route at the moment.
Massachusetts to South Carolina flights typically cost between $289 and $561 in January.The cheapest round-trip price found within the last 5 days was $209 on Delta (Jan 13-Jan 23).
How far ahead should I book a flight from Massachusetts to South Carolina?
The price you pay for your flight from Massachusetts to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 82 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Massachusetts to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Massachusetts to South Carolina. Price data was last updated on November 7, 2026.
Travelers seeking maximum savings on their Massachusetts to South Carolina flight should consider departing on Wednesday mornings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 12, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Massachusetts to South Carolina by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Massachusetts to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Massachusetts to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Massachusetts to South Carolina by cabin class
Find flights from Massachusetts to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Massachusetts and South Carolina flights
Browse other Massachusetts and South Carolina flight options. Last updated on November 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Massachusetts after your stay in South Carolina
Massachusetts to South Carolina flights
Consider these flights traveling from Massachusetts to South Carolina.
Top 6 airlines flying from Massachusetts to South Carolina
Discover the top 6 airlines that operate flights from Massachusetts to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$260 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$119 | Average$369 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$151 | Average$380 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$368 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$206 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$451 | FlexibilityNo cancel fee | On-time63% |