$127+ Cheap flights from Massachusetts to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — CHS
Oct 30 — Nov 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Massachusetts to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Massachusetts to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from Massachusetts to South CarolinaExplore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Massachusetts to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:25 am -
2 stops11h 05m
Sat 10/317:45 am -
2 stops10h 20m
Deal found 9/29![Southwest logo]()
$235
This deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:17 am -
Nonstop2h 43m
Thu 11/510:50 am -
Nonstop2h 19m
Deal found 9/29![JetBlue logo]()
$241
This Super.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:18 am -
Nonstop2h 42m
Fri 11/134:05 pm -
Nonstop2h 49m
Deal found 9/25![JetBlue logo]()
$245
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:31 am -
2 stops6h 57m
Sat 11/77:00 pm -
1 stop5h 46m
Deal found 9/29![United Airlines logo]()
$246
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:04 pm -
Nonstop2h 32m
Sat 10/312:40 pm -
Nonstop2h 31m
Deal found 9/28![Delta logo]()
$249
This deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:17 am -
Nonstop2h 43m
Thu 10/2910:47 am -
Nonstop2h 18m
Deal found 9/26![JetBlue logo]()
$250
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop6h 01m
Mon 11/911:30 am -
1 stop6h 57m
Deal found 9/29![Delta logo]()
$253
This JetBlue deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:05 pm -
1 stop6h 26m
Tue 11/1710:50 am -
Nonstop2h 19m
Deal found 9/25![JetBlue logo]()
$254
This JetBlue deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:35 pm -
Nonstop2h 39m
Wed 11/119:40 am -
1 stop7h 19m
Deal found 9/29![JetBlue logo]()
$256
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop4h 21m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/28![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:15 am -
Nonstop2h 36m
Mon 11/165:19 pm -
1 stop5h 36m
Deal found 9/30![Delta logo]()
$259
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/28![Southwest logo]()
$263
Best flights from Massachusetts to South CarolinaDiscover carefully curated flight deals from Massachusetts to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Massachusetts to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:35 am -
2 stops13h 30m
Tue 11/108:00 am -
2 stops11h 05m
Deal found 9/30![Southwest logo]()
$235
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:05 pm -
Nonstop2h 34m
Sat 11/711:27 am -
Nonstop2h 28m
Deal found 9/29![Delta logo]()
$249
This JetBlue deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:05 pm -
1 stop7h 17m
Tue 12/812:43 pm -
1 stop7h 07m
Deal found 9/30![JetBlue logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
1 stop6h 35m
Sat 10/242:51 pm -
1 stop7h 08m
Deal found 9/27![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:00 am -
1 stop4h 25m
Tue 10/1312:29 pm -
2 stops9h 20m
Deal found 9/29![American Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:00 pm -
1 stop6h 40m
Mon 11/167:19 pm -
1 stop5h 49m
Deal found 9/29![Delta logo]()
$253
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/98:00 am -
1 stop7h 41m
Tue 12/155:00 pm -
1 stop4h 31m
Deal found 9/27![Delta logo]()
$281
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:10 pm -
2 stops7h 35m
Sun 12/138:15 am -
1 stop6h 15m
Deal found 9/25![Southwest logo]()
$340
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:38 am -
1 stop4h 57m
Sat 10/242:51 pm -
2 stops9h 08m
Deal found 9/30![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:04 pm -
Nonstop2h 32m
Tue 10/273:31 pm -
Nonstop2h 28m
Deal found 9/27![Delta logo]()
$289
This JetBlue deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/131:05 pm -
1 stop6h 26m
Sun 11/1510:50 am -
Nonstop2h 19m
Deal found 9/25![JetBlue logo]()
$368
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:38 am -
1 stop4h 57m
Wed 10/211:20 pm -
1 stop6h 05m
Deal found 9/29![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:10 pm -
1 stop6h 05m
Mon 11/97:35 pm -
1 stop4h 20m
Deal found 9/29![Southwest logo]()
$366
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:00 am -
1 stop4h 42m
Tue 11/34:15 pm -
1 stop6h 09m
Deal found 9/30![Delta logo]()
$310
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 am -
1 stop4h 58m
Sat 11/73:29 pm -
2 stops8h 30m
Deal found 9/28![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:25 am -
1 stop4h 30m
Sat 11/1410:35 am -
2 stops11h 30m
Deal found 9/29![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
1 stop7h 00m
Thu 10/293:31 pm -
Nonstop2h 28m
Deal found 9/27![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:38 am -
2 stops6h 48m
Wed 10/2110:23 am -
2 stops6h 23m
Deal found 9/27![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:15 am -
2 stops10h 00m
Mon 11/210:45 am -
2 stops11h 15m
Deal found 9/26![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:15 am -
1 stop7h 23m
Mon 10/266:08 pm -
1 stop4h 51m
Deal found 9/30![American Airlines logo]()
$499
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
3 stops14h 58m
Thu 11/125:40 am -
1 stop5h 11m
Deal found 9/28![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:10 pm -
2 stops8h 40m
Tue 11/38:10 am -
2 stops14h 00m
Deal found 9/30![Southwest logo]()
$397
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:38 am -
2 stops7h 32m
Tue 10/206:00 am -
2 stops6h 43m
Deal found 9/26![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:53 pm -
1 stop5h 04m
Wed 12/302:35 pm -
1 stop4h 40m
Deal found 9/27![American Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:55 am -
1 stop5h 19m
Wed 10/75:40 am -
1 stop7h 02m
Deal found 9/26![Delta logo]()
$399
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:10 am -
2 stops7h 50m
Sun 11/227:35 pm -
1 stop4h 20m
Deal found 9/29![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:57 pm -
1 stop6h 02m
Mon 11/92:52 pm -
2 stops7h 07m
Deal found 9/27![United Airlines logo]()
$374
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
Nonstop2h 47m
Mon 11/96:53 pm -
1 stop5h 01m
Deal found 9/29![Delta logo]()
$399
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:05 am -
1 stop7h 05m
Sun 11/85:09 am -
1 stop6h 13m
Deal found 9/25![American Airlines logo]()
$591
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/309:05 am -
2 stops10h 10m
Sun 11/17:35 pm -
1 stop4h 15m
Deal found 9/27![Southwest logo]()
$404
Last-minute flights from Massachusetts to South CarolinaDiscover last-minute flight deals from Massachusetts to South Carolina. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Massachusetts to South Carolina. Data last updated September 30, 2026 and is based on user searches.
This deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:00 am -
Nonstop2h 31m
Thu 10/13:04 pm -
Nonstop2h 56m
Deal found 9/29![JetBlue logo]()
$273
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:45 am -
2 stops8h 10m
Sat 10/247:00 am -
1 stop4h 24m
Deal found 9/25![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:04 pm -
Nonstop2h 32m
Tue 10/203:31 pm -
Nonstop2h 28m
Deal found 9/29![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:25 am -
2 stops11h 05m
Sat 10/317:45 am -
2 stops10h 20m
Deal found 9/29![Southwest logo]()
$235
This deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:17 am -
Nonstop2h 43m
Thu 10/2910:47 am -
Nonstop2h 18m
Deal found 9/26![JetBlue logo]()
$250
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:04 pm -
Nonstop2h 32m
Sat 10/312:40 pm -
Nonstop2h 31m
Deal found 9/28![Delta logo]()
$249
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop7h 30m
Sat 10/316:00 am -
1 stop5h 02m
Deal found 9/29![Delta logo]()
$253
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:30 am -
1 stop4h 21m
Sat 10/316:20 am -
2 stops8h 12m
Deal found 9/28![United Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Sat 10/316:40 am -
2 stops9h 15m
Deal found 9/28![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Wed 11/47:05 am -
1 stop10h 05m
Deal found 9/28![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:45 am -
2 stops9h 20m
Mon 11/28:50 pm -
2 stops11h 30m
Deal found 9/27![Southwest logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3112:00 pm -
1 stop5h 39m
Mon 11/27:00 pm -
1 stop5h 46m
Deal found 9/29![United Airlines logo]()
$269
One-way flights from Massachusetts to South CarolinaSearch for one-way flight options from Massachusetts to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Massachusetts to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:30 am -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$127
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:55 am -
2 stops10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:34 pm -
1 stop22h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Allegiant Air logo]()
$136
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:35 am -
2 stops14h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Southwest logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:27 am -
2 stops22h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:34 pm -
2 stops31h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:47 am -
1 stop21h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:47 am -
1 stop20h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Multiple Airlines logo]()
$154
This United Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:01 am -
1 stop7h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![United Airlines logo]()
$155
This Southwest deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:50 pm -
1 stop5h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Southwest logo]()
$157
This United Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:57 pm -
1 stop6h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/30![United Airlines logo]()
$160
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:38 am -
2 stops6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![United Airlines logo]()
$160
Find flight deals from Massachusetts to South Carolina
Keep the following information in mind while searching for Massachusetts to South Carolina flight deals. Data was last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (Southwest) |
One-way from | $127 (Delta) |
Popular in | April |
Cheapest in | January |
Average price | $380 |
Good round-trip deal | $320 or less |
Good one-way deal | $213 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Massachusetts to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Massachusetts to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Sat 11/14
5:57 pm-11:47 pm
1 stop5h 50m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Mon 10/26
5:30 am-1:00 pm
1 stop7h 30m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Thu 12/17
5:35 am-10:10 am
1 stop4h 35m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonGreenville
BOS Boston Logan Intl - GSP Greenville
BOSGSP
Boston Logan Intl
Tue 12/15
8:00 am-1:18 pm
1 stop5h 18m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$127
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Sun 11/8
7:31 am-1:56 pm
1 stop6h 25m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Tue 10/27
2:40 pm-7:11 pm
1 stop4h 31m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Tue 11/3
12:05 pm-2:39 pm
Nonstop2h 34m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
Quickest round-trip
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Tue 10/20
12:04 pm-2:36 pm
Nonstop2h 32m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
BostonMyrtle Beach
BOS Boston Logan Intl - MYR Myrtle Beach Intl
BOSMYR
Boston Logan Intl
Mon 10/26
6:00 am-10:21 am
1 stop4h 21m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
BostonCharleston
BOS Boston Logan Intl - CHS Charleston
BOSCHS
Boston Logan Intl
Tue 10/13
7:01 am-2:04 pm
1 stop7h 03m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Massachusetts to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Massachusetts with our price prediction graph.
BOS-GSP
BOS-CHS
BOS-MYR
BOS-CAE
BOS-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Massachusetts to South Carolina
USMA-USSC
BOS-GSP
BOS-CHS
BOS-MYR
BOS-CAE
What is the cheapest month to book a flight from Massachusetts to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Massachusetts to South Carolina (average of $219). Flying from Massachusetts to South Carolina in September is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MA to SC?
Find hourly flight availability from Massachusetts to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 30, 2026.
It’s optimal to fly from Massachusetts to South Carolina in the evening. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.
Weekly flight availability from Massachusetts to South Carolina
Explore weekly flight availability from Massachusetts to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 30, 2026.
The most flights from USMA to USSC are scheduled on a Monday (5 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).
How much does it cost to fly round-trip from Massachusetts to South Carolina?
Airfare is below average for this route at the moment.
Massachusetts to South Carolina flights typically cost between $279 and $573 in October.The cheapest round-trip price found within the last 5 days was $235 on Southwest (Oct 24-Oct 31).
How far ahead should I book a flight from Massachusetts to South Carolina?
The price you pay for your flight from Massachusetts to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 82 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Massachusetts to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Massachusetts to South Carolina. Price data was last updated on September 26, 2026.
Travelers seeking maximum savings on their Massachusetts to South Carolina flight should consider departing on Monday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 30, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Massachusetts to South Carolina by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Boarding
8.1
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentEdward,Sep 2026
MCO - BWI
Related info for your journey
Find useful and relevant information for your journey from Massachusetts to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Alternative routes for Massachusetts to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Massachusetts to South Carolina by cabin class
Find flights from Massachusetts to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Massachusetts and South Carolina flights
Browse other Massachusetts and South Carolina flight options. Last updated on September 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Massachusetts after your stay in South Carolina
Massachusetts to South Carolina flights
Consider these flights traveling from Massachusetts to South Carolina.
Top 6 airlines flying from Massachusetts to South Carolina
Discover the top 6 airlines that operate flights from Massachusetts to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$282 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$110 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$143 | Average$374 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$352 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$196 | Average$407 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$448 | FlexibilityNo cancel fee | On-time63% |