$471+ Cheap flights from Louisiana to Florence, SC (FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — FLO
Nov 20 — Nov 271
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Last-minute
Cheapest flights from Louisiana to FlorenceExplore the most affordable flight options available from Louisiana to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
Explore the most affordable flight options available from Louisiana to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 21, 2026.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:20 am -
1 stop5h 49m
Wed 11/252:35 pm -
1 stop4h 15m
Deal found 10/20![American Airlines logo]()
$471
Best flights from Louisiana to FlorenceDiscover carefully curated flight deals from Louisiana to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
Discover carefully curated flight deals from Louisiana to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 21, 2026.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:39 am -
2 stops8h 30m
Wed 11/252:35 pm -
1 stop4h 15m
Deal found 10/20![American Airlines logo]()
$598
Last-minute flights from Louisiana to FlorenceDiscover last-minute flight deals from Louisiana to Florence. Data last updated October 21, 2026 and is based on user searches.
Discover last-minute flight deals from Louisiana to Florence. Data last updated October 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:20 am -
1 stop5h 49m
Wed 11/252:35 pm -
1 stop4h 15m
Deal found 10/20![American Airlines logo]()
$471
Find flight deals from Louisiana to Florence
Keep the following information in mind while searching for Louisiana to Florence flight deals. Data was last updated October 21, 2026.
Round-trip from | $471 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Louisiana to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 21, 2026.
Use the filters below to find and compare flights from Louisiana to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
New OrleansFlorence
MSY New Orleans Louis Armstrong - FLO Florence
MSYFLO
New Orleans Louis Armstrong
Wed 11/18
5:39 am-3:09 pm
2 stops8h 30m
Florence
Wed 11/25
2:35 pm-5:50 pm
1 stop4h 15m
$598
Sorted by cheapest first
Best time to book a flight from Louisiana to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Louisiana with our price prediction graph.
MSY-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisiana to Florence
USLA-FLO
MSY-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
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