$596+ Cheap flights from Florence, SC (FLO) to Louisiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MSY
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Louisiana
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Last-minute
Cheapest flights from Florence to LouisianaExplore the most affordable flight options available from Florence to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Florence to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 10/286:29 am -
1 stop6h 40m
Deal found 9/2![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:24 am -
1 stop4h 10m
Fri 10/306:50 pm -
1 stop4h 07m
Deal found 9/2![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:43 pm -
1 stop4h 29m
Fri 9/188:18 am -
1 stop4h 00m
Deal found 9/4![American Airlines logo]()
$698
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:24 am -
1 stop4h 10m
Sun 10/45:49 am -
2 stops7h 21m
Deal found 9/5![American Airlines logo]()
$758
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 9/306:00 am -
2 stops15h 58m
Deal found 9/2![American Airlines logo]()
$1,344
Best flights from Florence to LouisianaDiscover carefully curated flight deals from Florence to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Florence to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 10/286:29 am -
1 stop6h 40m
Deal found 9/2![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:24 am -
1 stop4h 10m
Fri 10/306:50 pm -
1 stop4h 07m
Deal found 9/2![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:24 am -
1 stop4h 10m
Sun 10/47:05 am -
1 stop6h 05m
Deal found 9/5![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:43 pm -
2 stops10h 15m
Fri 9/185:52 pm -
1 stop4h 06m
Deal found 9/4![American Airlines logo]()
$730
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 9/306:00 am -
2 stops15h 58m
Deal found 9/2![American Airlines logo]()
$1,344
Last-minute flights from Florence to LouisianaDiscover last-minute flight deals from Florence to Louisiana. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Louisiana. Data last updated September 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:43 pm -
1 stop4h 29m
Fri 9/188:18 am -
1 stop4h 00m
Deal found 9/4![American Airlines logo]()
$698
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 10/286:29 am -
1 stop6h 40m
Deal found 9/2![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:24 am -
1 stop4h 10m
Fri 10/306:50 pm -
1 stop4h 07m
Deal found 9/2![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:43 pm -
1 stop4h 29m
Wed 9/306:00 am -
2 stops15h 58m
Deal found 9/2![American Airlines logo]()
$1,344
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:24 am -
1 stop4h 10m
Sun 10/45:49 am -
2 stops7h 21m
Deal found 9/5![American Airlines logo]()
$758
Find flight deals from Florence to Louisiana
Keep the following information in mind while searching for Florence to Louisiana flight deals. Data was last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $596 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Florence to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceNew Orleans
FLO Florence - MSY New Orleans Louis Armstrong
FLOMSY
Florence
Mon 9/28
1:43 pm-5:12 pm
1 stop4h 29m
New Orleans Louis Armstrong
Wed 10/28
6:29 am-2:09 pm
1 stop6h 40m
$596
Quickest round-trip
FlorenceNew Orleans
FLO Florence - MSY New Orleans Louis Armstrong
FLOMSY
Florence
Mon 9/28
6:24 am-9:34 am
1 stop4h 10m
New Orleans Louis Armstrong
Fri 10/30
6:50 pm-11:57 pm
1 stop4h 07m
$633
FlorenceNew Orleans
FLO Florence - MSY New Orleans Louis Armstrong
FLOMSY
Florence
Thu 10/1
6:24 am-9:34 am
1 stop4h 10m
New Orleans Louis Armstrong
Sun 10/4
7:05 am-2:10 pm
1 stop6h 05m
$633
FlorenceNew Orleans
FLO Florence - MSY New Orleans Louis Armstrong
FLOMSY
Florence
Tue 9/15
1:43 pm-10:58 pm
2 stops10h 15m
New Orleans Louis Armstrong
Fri 9/18
5:52 pm-10:58 pm
1 stop4h 06m
$730
FlorenceNew Orleans
FLO Florence - MSY New Orleans Louis Armstrong
FLOMSY
Florence
Mon 9/28
1:43 pm-5:12 pm
1 stop4h 29m
New Orleans Louis Armstrong
Wed 9/30
6:00 am-10:58 pm
2 stops15h 58m
$1,344
Sorted by cheapest first
Best time to book a flight from Florence to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Florence with our price prediction graph.
FLO-MSY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Louisiana
FLO-USLA
FLO-MSY
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Florence to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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