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$416+ Cheap flights from Louisiana to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/4. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — FLO
May 2 — May 91
Sat 5/2
Sat 5/9
1 adult, Economy
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Cheap flight deals from Louisiana to Florence

Cheapest flights from Louisiana to Florence
Explore the most affordable flight options available from Louisiana to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.

This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:33 pm
BTR
-
FLO
1 stop4h 14m
American Airlines
Mon 4/204:16 pm
FLO
-
BTR
1 stop6h 09m
American Airlines
Deal found 4/1$603
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:01 am
LFT
-
FLO
1 stop6h 08m
American Airlines
Sun 9/136:31 pm
FLO
-
LFT
1 stop4h 13m
American Airlines
Deal found 3/29$762

Find flight deals from Louisiana to Florence

Keep the following information in mind while searching for Louisiana to Florence flight deals. Data was last updated April 2, 2026.

Round-trip from

$603
(American Airlines)

One-way from

$416
(American Airlines)
From Louisiana to Florence
Search Deals
One-way flight from Louisiana to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisiana to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Louisiana to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Baton RougeFlorence

BTR - FLO

BTRFLO

Baton Rouge Ryan

Thu 4/16

4:33 pm-9:47 pm

1 stop4h 14m

Florence

Mon 4/20

4:16 pm-9:25 pm

1 stop6h 09m

$603
Quickest round-trip

LafayetteFlorence

LFT - FLO

LFTFLO

Lafayette Regional

Fri 9/4

7:01 am-2:09 pm

1 stop6h 08m

Florence

Sun 9/13

6:31 pm-9:44 pm

1 stop4h 13m

$762
Cheapest one-way
Quickest one-way

LafayetteFlorence

LFT - FLO

LFTFLO

Lafayette Regional

Fri 9/4

7:01 am-2:09 pm

1 stop6h 08m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/28

Sorted by cheapest first

Best time to book a flight from Louisiana to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Louisiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisiana to Florence

What is the cheapest month to book a flight from Louisiana to Florence, South Carolina?

Currently, February is the cheapest month in which you can book a flight from Louisiana to Florence, South Carolina (average of $86). Flying from Louisiana to Florence, South Carolina in March is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Louisiana to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Louisiana?

    For a flight from Louisiana to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from Louisiana to Florence, South Carolina?

    Departing from Louisiana to Florence, South Carolina will take you 4h 14m. Louisiana and Florence, South Carolina are separated by a distance of 712 mi.

  • Can I find deals for flights from Louisiana to Florence that include hotel bookings?

    Yes. In addition to deals on Louisiana to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisiana to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisiana to Florence.

  • Can I find deals for business class flights from Louisiana to Florence?

    Yes. Cheapflights offers flight deals from Louisiana to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisiana to Florence, South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Louisiana to Florence, South Carolina (average of $86). Flying from Louisiana to Florence, South Carolina in March is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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