How long is the flight from Columbus to Florence, South Carolina?

There are many flights that can get you from Columbus to Florence, South Carolina in 4h 33m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 438 mi.

In terms of precipitation, rainfall in Florence, South Carolina ranges from 2.5 - 5.4 inches per month. July is typically the wettest month, when rainfall can reach 5.4 in. November is typically the driest time to visit Florence, South Carolina when rainfall is around 2.5 in.

If weather is an important factor for your trip to Florence, South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

What is the cheapest time of day to fly from CMH to FLO?

When flying from Columbus to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Florence from Columbus?

Florence (FLO), located 2.3 mi from the city center, is the airport you fly into when you book flights from Columbus to Florence. 0 airlines have flights to Florence from Columbus on a regular basis. Booking flights from Columbus to Florence should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

Can I find deals for flights from Columbus to Florence that include hotel bookings?

Yes. In addition to deals on Columbus to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Columbus to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Florence.

Can I find deals for business class flights from Columbus to Florence?

Yes. Cheapflights offers flight deals from Columbus to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$400+ Cheap Flights from Columbus to Florence, SC

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Cheap flight deals from Columbus to Florence

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Cheapest flights from Columbus to Florence
Explore the most affordable flight options available from Columbus to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Fri 9/188:45 am -

1 stop4h 33m

Tue 9/221:43 pm -

1 stop4h 07m

Deal found 9/3

$645

Tue 10/135:05 pm -

1 stop6h 07m

Wed 10/145:09 am -

1 stop4h 14m

Deal found 9/1

$897

Find flight deals from Columbus to Florence

Round-trip from	$645 (American Airlines)
One-way from	$400 (American Airlines)

From Columbus to Florence

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One-way flight from Columbus to Florence

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Route

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Price

Cheapest round-trip

ColumbusFlorence

CMH Columbus - FLO Florence

CMHFLO

Columbus

Mon 11/9

10:16 am-10:59 pm

2 stops12h 43m

Florence

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$400

Quickest round-trip

ColumbusFlorence

CMH Columbus - FLO Florence

CMHFLO

Columbus

Sun 11/8

8:20 pm-11:56 pm

1 stop3h 36m

Florence

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$483

ColumbusFlorence

CMH Columbus - FLO Florence

CMHFLO

Columbus

Thu 9/17

8:45 am-1:18 pm

1 stop4h 33m

Florence

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$483

ColumbusFlorence

CMH Columbus - FLO Florence

CMHFLO

Columbus

Fri 9/18

8:45 am-1:18 pm

1 stop4h 33m

Florence

Tue 9/22

1:43 pm-5:50 pm

1 stop4h 07m

$645

ColumbusFlorence

CMH Columbus - FLO Florence

CMHFLO

Columbus

Tue 10/13

5:05 pm-11:12 pm

1 stop6h 07m

Florence

Wed 10/14

5:09 am-9:23 am

1 stop4h 14m

$897

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/1

Sorted by cheapest first

Best time to book a flight from Columbus to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Columbus with our price prediction graph.

C01-FLO

CMH-FLO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

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Everything you need to know about your flight from Columbus to Florence

C01-FLO

CMH-FLO

No data available for this route at this time. Please check back soon.

Related info for your journey

What airport do you fly into for flights to Florence from Columbus?
Florence (FLO), located 2.3 mi from the city center, is the airport you fly into when you book flights from Columbus to Florence. 0 airlines have flights to Florence from Columbus on a regular basis. Booking flights from Columbus to Florence should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.
How long is the flight from Columbus to Florence, South Carolina?
There are many flights that can get you from Columbus to Florence, South Carolina in 4h 33m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 438 mi.
Can I find deals for flights from Columbus to Florence that include hotel bookings?
Yes. In addition to deals on Columbus to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Columbus to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Florence.
Can I find deals for business class flights from Columbus to Florence?
Yes. Cheapflights offers flight deals from Columbus to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$400+ Cheap flights from Columbus to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Columbus to Florence with Cheapflights

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Cheap flight deals from Columbus to Florence

Cheapest flights from Columbus to FlorenceExplore the most affordable flight options available from Columbus to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Explore the most affordable flight options available from Columbus to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Best flights from Columbus to FlorenceDiscover carefully curated flight deals from Columbus to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Discover carefully curated flight deals from Columbus to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Last-minute flights from Columbus to FlorenceDiscover last-minute flight deals from Columbus to Florence. Data last updated September 6, 2026 and is based on user searches.

Discover last-minute flight deals from Columbus to Florence. Data last updated September 6, 2026 and is based on user searches.

One-way flights from Columbus to FlorenceSearch for one-way flight options from Columbus to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.

Search for one-way flight options from Columbus to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.

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Related info for your journey

What airport do you fly into for flights to Florence from Columbus?

How long is the flight from Columbus to Florence, South Carolina?

Can I find deals for flights from Columbus to Florence that include hotel bookings?

How can I find direct flights from Columbus to Florence?

Can I find deals for business class flights from Columbus to Florence?

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Cheapest flights from Columbus to Florence
Explore the most affordable flight options available from Columbus to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 6, 2026.

Best flights from Columbus to Florence
Discover carefully curated flight deals from Columbus to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 6, 2026.

Last-minute flights from Columbus to Florence
Discover last-minute flight deals from Columbus to Florence. Data last updated September 6, 2026 and is based on user searches.

One-way flights from Columbus to Florence
Search for one-way flight options from Columbus to Florence. Find affordable one-way fares based on user searches. Data last updated September 6, 2026.