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$224+ Cheap flights from California to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — FLO
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from California to Florence

Cheapest flights from California to Florence
Explore the most affordable flight options available from California to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:50 pmSFO - FLO
1 stop7h 00mAmerican Airlines
Sat 1/175:36 pmFLO - SFO
1 stop7h 49mAmerican Airlines
Deal found 12/13$460
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:49 amLAX - FLO
1 stop8h 37mAmerican Airlines
Sat 1/36:30 pmFLO - LAX
1 stop7h 38mAmerican Airlines
Deal found 12/15$601
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:45 amLAX - FLO
1 stop9h 30mAmerican Airlines
Thu 1/15:15 amFLO - LAX
1 stop7h 12mAmerican Airlines
Deal found 12/13$929
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:17 pmSJC - FLO
2 stops14h 09mAmerican Airlines
Wed 12/315:15 amFLO - SJC
2 stops12h 37mAmerican Airlines
Deal found 12/15$1,241

Find flight deals from California to Florence

Keep the following information in mind while searching for California to Florence flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$507
(American Airlines)

One-way from

$224
(American Airlines)

Popular in

January

Cheapest in

October

Average price

$630
Provider with most accurate pricing for Los Angeles-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Florence flights.
Search Deals
From California to Florence
Search Deals
One-way flight from California to Florence
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from California to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from California to Florence that are best for you.

Fly from

California

Fly to

Florence

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Thu 2/12

7:00 am-5:45 pm

1 stop7h 45m

Florence

Tue 2/17

6:15 am-1:59 pm

1 stop10h 44m

$507

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 2/13

10:22 am-11:58 pm

2 stops10h 36m

Florence

Tue 2/17

6:15 am-1:59 pm

1 stop10h 44m

$512

SacramentoFlorence

SMF - FLO

SMFFLO

Sacramento Intl

Wed 5/27

10:42 pm-10:14 am

1 stop8h 32m

Florence

Sun 5/31

11:16 am-4:38 pm

1 stop8h 22m

$517

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Thu 2/12

7:00 am-5:45 pm

1 stop7h 45m

Florence

Mon 2/16

5:15 am-12:30 pm

1 stop10h 15m

$537

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 2/13

1:30 pm-11:58 pm

1 stop7h 28m

Florence

Mon 2/16

6:18 pm-11:14 pm

1 stop7h 56m

$567

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Fri 12/19

12:49 am-12:26 pm

1 stop8h 37m

Florence

Sat 1/3

6:30 pm-11:08 pm

1 stop7h 38m

$601

Las VegasFlorence

LAS - FLO

LASFLO

Las Vegas Harry Reid Intl

Fri 1/23

6:22 am-10:43 pm

2 stops13h 21m

Florence

Sat 1/31

5:36 pm-10:34 pm

1 stop7h 58m

$692

Los AngelesFlorence

LAX - FLO

LAXFLO

Los Angeles

Sun 12/28

11:45 am-12:15 am

1 stop9h 30m

Florence

Thu 1/1

5:15 am-9:27 am

1 stop7h 12m

$929

San JoseFlorence

SJC - FLO

SJCFLO

San Jose

Sun 12/28

7:17 pm-12:26 pm

2 stops14h 09m

Florence

Wed 12/31

5:15 am-2:52 pm

2 stops12h 37m

$1,241

RenoFlorence

RNO - FLO

RNOFLO

Reno

Tue 4/28

7:32 pm-10:02 am

2 stops11h 30m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Best time to book a flight from California to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from California with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from California to Florence

What is the cheapest month to book a flight from California to Florence, South Carolina?

Currently, December is the cheapest month in which you can book a flight from California to Florence, South Carolina (average of $111). Flying from California to Florence, South Carolina in November is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from California to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from California?

    Most people fly into Florence (FLO) if they book a flight to Florence from California. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from California to Florence, South Carolina?

    American Airlines can get you from California to Florence, South Carolina in just under 7h 45m. Your travel time can differ by up to . Airlines will cover a distance of 2377 mi.

  • What are the most popular routes from California to Florence, South Carolina?

    The most popular route from California to Florence, South Carolina is Las Vegas Harry Reid Intl - Florence. You may also consider Los Angeles - Florence or San Francisco - Florence.

  • Can I find deals for flights from California to Florence that include hotel bookings?

    Yes. In addition to deals on California to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from California to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from California to Florence.

  • Can I find deals for business class flights from California to Florence?

    Yes. Cheapflights offers flight deals from California to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from California to Florence, South Carolina?

    Currently, December is the cheapest month in which you can book a flight from California to Florence, South Carolina (average of $111). Flying from California to Florence, South Carolina in November is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from California to Florence

Discover the top airline that operate flights from California to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$400Average$571FlexibilityNo cancel feeOn-time71%

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