HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$349+ Cheap flights from Boston to Florence, SC (BOS - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — FLO
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Boston to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Boston to Florence

Cheapest flights from Boston to Florence
Explore the most affordable flight options available from Boston to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:40 pm
BOS
-
FLO
1 stop6h 12m
American Airlines
Wed 4/225:20 am
FLO
-
BOS
1 stop5h 52m
American Airlines
Deal found 2/19$349
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:40 pm
BOS
-
FLO
1 stop6h 12m
American Airlines
Sat 5/164:16 pm
FLO
-
BOS
1 stop5h 38m
American Airlines
Deal found 2/20$369
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:26 pm
BOS
-
FLO
1 stop5h 24m
American Airlines
Sun 4/55:16 am
FLO
-
BOS
1 stop4h 49m
American Airlines
Deal found 2/16$379
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:40 pm
BOS
-
FLO
1 stop6h 12m
American Airlines
Sat 5/164:16 pm
FLO
-
BOS
1 stop5h 38m
American Airlines
Deal found 2/20$389
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:30 pm
BOS
-
FLO
1 stop6h 27m
American Airlines
Sun 3/225:16 am
FLO
-
BOS
1 stop4h 49m
American Airlines
Deal found 2/16$394
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/212:26 pm
BOS
-
FLO
1 stop5h 24m
American Airlines
Sun 4/55:16 am
FLO
-
BOS
1 stop4h 49m
American Airlines
Deal found 2/16$399
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:26 pm
BOS
-
FLO
1 stop5h 24m
American Airlines
Mon 3/96:20 pm
FLO
-
BOS
1 stop4h 31m
American Airlines
Deal found 2/20$419

Find flight deals from Boston to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Boston (BOS) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$349
(American Airlines)

Popular in

July

Cheapest in

March

Average price

$372
Provider with most accurate pricing for Boston Logan Intl-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Florence flights.
Search Deals
From Boston Logan Intl to Florence
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($45 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Boston to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Boston to Florence that are best for you.

Fly from

Boston

Fly to

Florence

Route

Depart

Return

Price

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 4/15

5:40 pm-11:52 pm

1 stop6h 12m

Florence

Wed 4/22

5:20 am-11:12 am

1 stop5h 52m

$349

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 4/1

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Sun 4/5

5:16 am-10:05 am

1 stop4h 49m

$379

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/26

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Sun 3/29

6:20 pm-11:23 pm

1 stop5h 03m

$389

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/19

5:30 pm-11:57 pm

1 stop6h 27m

Florence

Sun 3/22

5:16 am-10:05 am

1 stop4h 49m

$394

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 4/2

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Sun 4/5

5:16 am-10:05 am

1 stop4h 49m

$399

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Thu 3/5

12:26 pm-5:50 pm

1 stop5h 24m

Florence

Mon 3/9

6:20 pm-10:51 pm

1 stop4h 31m

$419

BostonFlorence

BOS - FLO

BOSFLO

Boston Logan Intl

Wed 3/4

10:00 am-5:21 pm

1 stop7h 21m

$383

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Compare providers for flights from Boston to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Boston to Florence in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Boston-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Boston-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Boston-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Boston-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Boston-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Boston to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Boston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Boston to Florence

What is the cheapest month to book a flight from Boston to Florence, South Carolina?

Currently, August is the cheapest month in which you can book a flight from Boston to Florence, South Carolina (average of $58). Flying from Boston to Florence, South Carolina in January is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated February 20, 2026.
See what other customers who have flown with American Airlines from Boston to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,334 reviews

Boarding

7.5

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,334 reviews
American Airlines
7.2
Good
11,334 reviews

Boarding

7.5

Food

6.4

Overall

7.2

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Boston to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Boston to Florence, South Carolina?

    Departing from Boston to Florence, South Carolina will take you 6h 12m. There are 735 mi between Boston and Florence, South Carolina.

  • What is the cheapest airline to fly from Boston to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($279), offers the cheapest pricing from Boston to Florence, South Carolina. You may be able to fly from Boston to Florence, South Carolina for 40% less than the average price by searching for this airline.

  • Can I find deals for flights from Boston to Florence that include hotel bookings?

    Yes. In addition to deals on Boston to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Boston to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Boston to Florence.

  • Can I find deals for business class flights from Boston to Florence?

    Yes. Cheapflights offers flight deals from Boston to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Boston to Florence, South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Boston to Florence, South Carolina (average of $58). Flying from Boston to Florence, South Carolina in January is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Boston to Florence

Discover the top airline that operate flights from Boston to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$279Average$454FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights