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$414+ Cheap flights from Philadelphia to Florence, SC (PHL - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Philadelphia to Florence

Cheapest flights from Philadelphia to Florence
Explore the most affordable flight options available from Philadelphia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:17 pm
PHL
-
FLO
1 stop4h 40m
American Airlines
Wed 4/15:16 am
FLO
-
PHL
1 stop4h 39m
American Airlines
Deal found 3/22$525
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:38 pm
PHL
-
FLO
1 stop5h 30m
American Airlines
Wed 4/15:16 am
FLO
-
PHL
2 stops10h 10m
American Airlines
Deal found 3/22$530
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:14 pm
PHL
-
FLO
2 stops7h 54m
American Airlines
Tue 3/316:15 am
FLO
-
PHL
2 stops9h 11m
American Airlines
Deal found 3/22$535
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:17 pm
PHL
-
FLO
1 stop4h 40m
American Airlines
Tue 3/316:15 am
FLO
-
PHL
2 stops9h 11m
American Airlines
Deal found 3/19$547
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:44 pm
PHL
-
FLO
1 stop4h 29m
American Airlines
Mon 9/285:31 am
FLO
-
PHL
1 stop4h 13m
American Airlines
Deal found 3/22$559
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:17 pm
PHL
-
FLO
1 stop4h 40m
American Airlines
Sun 4/55:16 am
FLO
-
PHL
1 stop4h 39m
American Airlines
Deal found 3/20$573
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:46 pm
PHL
-
FLO
1 stop3h 35m
American Airlines
Thu 4/25:16 am
FLO
-
PHL
2 stops10h 10m
American Airlines
Deal found 3/22$578
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/233:14 pm
PHL
-
FLO
2 stops8h 43m
American Airlines
Wed 4/15:16 am
FLO
-
PHL
2 stops10h 10m
American Airlines
Deal found 3/22$583
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:46 pm
PHL
-
FLO
1 stop4h 04m
American Airlines
Tue 3/316:15 am
FLO
-
PHL
2 stops9h 11m
American Airlines
Deal found 3/19$595
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:17 pm
PHL
-
FLO
1 stop4h 40m
American Airlines
Sat 3/285:16 am
FLO
-
PHL
2 stops7h 39m
American Airlines
Deal found 3/22$617
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:46 pm
PHL
-
FLO
1 stop4h 04m
American Airlines
Sun 3/296:20 pm
FLO
-
PHL
1 stop3h 39m
American Airlines
Deal found 3/22$621

Find flight deals from Philadelphia to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Philadelphia (PHL) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$573
(American Airlines)

One-way from

$414
(American Airlines)
Provider with most accurate pricing for Philadelphia-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Philadelphia-Florence flights.
Search Deals
From Philadelphia to Florence
Search Deals
One-way flight from Philadelphia to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Philadelphia to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 3/28

5:37 pm-11:57 pm

1 stop6h 20m

Florence

Wed 4/1

6:20 pm-9:59 pm

1 stop3h 39m

$525

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 3/28

5:37 pm-11:57 pm

1 stop6h 20m

Florence

Tue 3/31

5:58 pm-11:14 pm

1 stop5h 16m

$525

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 3/27

7:17 pm-11:57 pm

1 stop4h 40m

Florence

Sat 3/28

6:25 pm-11:59 pm

1 stop5h 34m

$573

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 3/28

5:37 pm-11:57 pm

1 stop6h 20m

Florence

Mon 3/30

6:20 pm-9:59 pm

1 stop3h 39m

$573

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 3/28

5:37 pm-11:57 pm

1 stop6h 20m

Florence

Thu 4/2

6:20 pm-11:59 pm

1 stop5h 39m

$573

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 3/26

1:46 pm-5:50 pm

1 stop4h 04m

Florence

Tue 3/31

6:15 am-12:54 pm

1 stop6h 39m

$573
Quickest round-trip

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 3/26

1:46 pm-5:50 pm

1 stop4h 04m

Florence

Mon 3/30

6:20 pm-9:59 pm

1 stop3h 39m

$621

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 3/26

1:46 pm-5:50 pm

1 stop4h 04m

Florence

Sun 3/29

6:20 pm-9:59 pm

1 stop3h 39m

$621
Cheapest one-way
Quickest one-way

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 5/2

11:50 am-3:50 pm

1 stop4h 00m

$414

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 5/22

8:20 am-2:10 pm

1 stop5h 50m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Sorted by cheapest first

Compare providers for flights from Philadelphia to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Philadelphia to Florence in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Philadelphia-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Philadelphia-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Philadelphia-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Philadelphia-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Philadelphia-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Philadelphia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Philadelphia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Philadelphia to Florence

What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

Currently, April is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $46). Flying from Philadelphia to Florence, South Carolina in July is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Philadelphia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Philadelphia to Florence, South Carolina?

    American Airlines can get you from Philadelphia to Florence, South Carolina in just under 6h 20m. Your travel time can differ by up to . Airlines will cover a distance of 464 mi.

  • Can I find deals for flights from Philadelphia to Florence that include hotel bookings?

    Yes. In addition to deals on Philadelphia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Philadelphia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Philadelphia to Florence.

  • Can I find deals for business class flights from Philadelphia to Florence?

    Yes. Cheapflights offers flight deals from Philadelphia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $46). Flying from Philadelphia to Florence, South Carolina in July is currently the most expensive (average of $79). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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