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$426+ Cheap flights from Philadelphia to Florence, SC (PHL - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Philadelphia to Florence

Cheapest flights from Philadelphia to Florence
Explore the most affordable flight options available from Philadelphia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:34 amPHL - FLO
1 stop3h 52mAmerican Airlines
Wed 12/315:15 amFLO - PHL
1 stop4h 24mAmerican Airlines
Deal found 12/17$464
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:34 amPHL - FLO
1 stop3h 52mAmerican Airlines
Sat 1/35:15 amFLO - PHL
2 stops9h 29mAmerican Airlines
Deal found 12/17$469
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amPHL - FLO
1 stop6h 42mAmerican Airlines
Sat 1/35:15 amFLO - PHL
1 stop4h 24mAmerican Airlines
Deal found 12/17$482
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amPHL - FLO
1 stop6h 42mAmerican Airlines
Wed 12/315:15 amFLO - PHL
2 stops9h 29mAmerican Airlines
Deal found 12/17$487
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:34 amPHL - FLO
1 stop3h 52mAmerican Airlines
Thu 1/16:30 pmFLO - PHL
1 stop3h 21mAmerican Airlines
Deal found 12/17$512
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Sat 1/35:15 amFLO - PHL
1 stop4h 24mAmerican Airlines
Deal found 12/17$513
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:34 amPHL - FLO
1 stop3h 52mAmerican Airlines
Sun 1/45:15 amFLO - PHL
2 stops9h 41mAmerican Airlines
Deal found 12/17$517
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amPHL - FLO
1 stop6h 42mAmerican Airlines
Wed 12/315:15 amFLO - PHL
2 stops9h 29mAmerican Airlines
Deal found 12/17$518
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amPHL - FLO
1 stop6h 42mAmerican Airlines
Thu 1/16:30 pmFLO - PHL
1 stop5h 24mAmerican Airlines
Deal found 12/17$530
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amPHL - FLO
1 stop6h 42mAmerican Airlines
Sun 1/45:15 amFLO - PHL
2 stops9h 29mAmerican Airlines
Deal found 12/17$535
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Fri 1/26:30 pmFLO - PHL
1 stop5h 24mAmerican Airlines
Deal found 12/17$561

Find flight deals from Philadelphia to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Philadelphia (PHL) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$464
(American Airlines)

One-way from

$426
(American Airlines)
Provider with most accurate pricing for Philadelphia-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Philadelphia-Florence flights.
Search Deals
From Philadelphia to Florence
Search Deals
One-way flight from Philadelphia to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Philadelphia to Florence that are best for you.

Fly from

Philadelphia

Fly to

Florence

Route

Depart

Return

Price

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 12/31

1:45 pm-7:38 pm

1 stop5h 53m

Florence

Tue 1/6

5:36 pm-11:40 pm

1 stop6h 04m

$464

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 1/1

6:00 am-12:26 pm

1 stop6h 26m

Florence

Wed 1/7

6:15 am-10:23 am

1 stop4h 08m

$464

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 1/14

4:51 pm-10:43 pm

1 stop5h 52m

Florence

Wed 1/21

6:15 am-12:30 pm

1 stop6h 15m

$464

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 12/31

1:45 pm-6:05 pm

1 stop4h 20m

Florence

Wed 1/7

5:36 pm-11:40 pm

1 stop6h 04m

$464

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 1/1

6:00 am-12:26 pm

1 stop6h 26m

Florence

Tue 1/6

5:36 pm-9:05 pm

1 stop3h 29m

$464

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 12/27

6:00 am-12:42 pm

1 stop6h 42m

Florence

Wed 12/31

6:30 pm-9:53 pm

1 stop3h 23m

$482

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 12/27

6:00 am-12:42 pm

1 stop6h 42m

Florence

Sat 1/3

5:15 am-9:39 am

1 stop4h 24m

$482

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Fri 1/9

6:30 pm-10:43 pm

1 stop4h 13m

$426

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Compare providers for flights from Philadelphia to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Philadelphia to Florence in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Philadelphia-Florence, South Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Philadelphia-Florence, South Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Philadelphia-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Philadelphia-Florence, South Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Philadelphia-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Philadelphia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Philadelphia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Philadelphia to Florence

What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $33). Flying from Philadelphia to Florence, South Carolina in July is currently the most expensive (average of $78). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Philadelphia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Philadelphia to Florence, South Carolina?

    American Airlines can get you from Philadelphia to Florence, South Carolina in just under 5h 53m. Your travel time can differ by up to . Airlines will cover a distance of 464 mi.

  • Can I find deals for flights from Philadelphia to Florence that include hotel bookings?

    Yes. In addition to deals on Philadelphia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Philadelphia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Philadelphia to Florence.

  • Can I find deals for business class flights from Philadelphia to Florence?

    Yes. Cheapflights offers flight deals from Philadelphia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $33). Flying from Philadelphia to Florence, South Carolina in July is currently the most expensive (average of $78). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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