HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$443+ Cheap flights from Milwaukee to Florence, SC (MKE - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/13. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — FLO
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Milwaukee to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Milwaukee to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$443
(American Airlines)
From Milwaukee-Mitchell to Florence
Search Deals

Find flight deals from Milwaukee to Florence

Cheapest flights from Milwaukee to Florence
Explore the most affordable flight options available from Milwaukee to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/138:10 amMKE - FLO
1 stop5h 54mAmerican Airlines
Sat 8/1611:15 amFLO - MKE
1 stop5h 35mAmerican Airlines
Deal found 7/1$443

Cheapflights Fare Finder

Customize your flight search to find flights from Milwaukee to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Milwaukee to Florence that are best for you.

Fly from

Milwaukee

Fly to

Florence

Route

Depart

Return

Price

MilwaukeeFlorence

MKE - FLO

MKEFLO

Milwaukee-Mitchell

Wed 8/13

8:10 am-3:04 pm

1 stop5h 54m

Florence

Sat 8/16

11:15 am-3:50 pm

1 stop5h 35m

$443

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Milwaukee to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Florence

What is the cheapest month to book a flight from Milwaukee to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Milwaukee to Florence, South Carolina (average of $366). Flying from Milwaukee to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with American Airlines from Milwaukee to Florence to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Comfort

7.2

Crew

8.0

Boarding

7.5

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Milwaukee to Florence that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Florence.

  • Can I find deals for business class flights from Milwaukee to Florence?

    Yes. Cheapflights offers flight deals from Milwaukee to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Milwaukee to Florence, South Carolina (average of $366). Flying from Milwaukee to Florence, South Carolina in October is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milwaukee?

Book flights to Milwaukee if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Milwaukee to Florence

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Charlotte flights
Minneapolis to Savannah flights
O'Hare Intl to Savannah flights
Minneapolis to Charleston flights
O'Hare Intl to Charleston flights
Minneapolis to Charlotte flights
O'Hare Intl to Myrtle Beach flights
Minneapolis to Myrtle Beach flights
O'Hare Intl to Columbia flights
O'Hare Intl to Greenville flights
Madison to Charleston flights
Appleton to Charlotte flights
Appleton to Savannah flights
Madison to Charlotte flights
Milwaukee to Charlotte flights
Milwaukee to Savannah flights
Milwaukee to Greenville flights
Milwaukee to Charleston flights
Appleton to Charleston flights
O'Hare Intl to Hilton Head Island flights
Milwaukee to Myrtle Beach flights
Madison to Myrtle Beach flights
Minneapolis to Augusta flights
Minneapolis to Greenville flights
Madison to Savannah flights
Green Bay to Savannah flights
Minneapolis to Columbia flights
O'Hare Intl to Augusta flights
Milwaukee to Columbia flights
Minneapolis to Hilton Head Island flights
Appleton to Myrtle Beach flights
Green Bay to Charleston flights
Appleton to Greenville flights
Green Bay to Myrtle Beach flights
Green Bay to Charlotte flights
Wausau to Charlotte flights
Appleton to Hilton Head Island flights
Madison to Greenville flights
Duluth to Charleston flights
Milwaukee to Hilton Head Island flights
Madison to Hilton Head Island flights
La Crosse to Charleston flights
O'Hare Intl to Florence flights
Milwaukee to Augusta flights
Green Bay to Hilton Head Island flights
Wausau to Savannah flights
Appleton to Columbia flights
Wausau to Myrtle Beach flights
Appleton to Augusta flights
Wausau to Columbia flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.