$330+ Cheap flights from Wilmington to Des Moines (ILM - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/21. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
May 24 — May 311
Round-trip
1 adult, Economy
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Find cheap flights from Wilmington to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wilmington to Des Moines
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Best
Last-minute
One-way
Cheapest flights from Wilmington to Des MoinesExplore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:20 pm
ILM
- DSM
1 stop24h 52m
Multiple Airlines
Thu 5/284:41 pm
DSM
- ILM
2 stops26h 28m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:50 am
ILM
- DSM
1 stop6h 20m
American Airlines
Sat 5/231:37 pm
DSM
- ILM
1 stop7h 14m
American Airlines
Deal found 4/22![American Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:39 pm
ILM
- DSM
1 stop8h 45m
Multiple Airlines
Mon 5/253:57 pm
DSM
- ILM
2 stops18h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$373
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:00 pm
ILM
- DSM
1 stop4h 48m
American Airlines
Mon 8/245:00 am
DSM
- ILM
2 stops7h 22m
American Airlines
Deal found 4/20![American Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:18 pm
ILM
- DSM
1 stop5h 14m
Delta
Sun 5/249:04 am
DSM
- ILM
1 stop7h 29m
Delta
Deal found 4/20![Delta logo]()
$431
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:48 am
ILM
- DSM
1 stop5h 55m
Delta
Sun 6/216:43 am
DSM
- ILM
1 stop6h 47m
Delta
Deal found 4/23![Delta logo]()
$435
This KAYAK deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:27 pm
ILM
- DSM
1 stop5h 05m
Delta
Fri 5/295:28 pm
DSM
- ILM
2 stops24h 05m
Delta
Deal found 4/22![Delta logo]()
$452
Best flights from Wilmington to Des MoinesDiscover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
Discover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 24, 2026.
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:38 am
ILM
- DSM
1 stop5h 56m
American Airlines
Mon 8/248:10 am
DSM
- ILM
1 stop4h 12m
American Airlines
Deal found 4/20![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:18 pm
ILM
- DSM
1 stop5h 14m
Delta
Sun 5/249:04 am
DSM
- ILM
1 stop7h 29m
Delta
Deal found 4/20![Delta logo]()
$431
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
ILM
- DSM
2 stops15h 16m
United Airlines
Tue 5/128:00 am
DSM
- ILM
3 stops14h 44m
United Airlines
Deal found 4/23![United Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:20 pm
ILM
- DSM
1 stop27h 17m
Multiple Airlines
Sun 6/219:27 am
DSM
- ILM
1 stop10h 15m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:50 am
ILM
- DSM
1 stop6h 20m
American Airlines
Sat 5/231:37 pm
DSM
- ILM
1 stop7h 14m
American Airlines
Deal found 4/22![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:48 am
ILM
- DSM
1 stop5h 55m
Delta
Sun 6/216:43 am
DSM
- ILM
1 stop6h 47m
Delta
Deal found 4/23![Delta logo]()
$435
This KAYAK deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:27 pm
ILM
- DSM
1 stop5h 05m
Delta
Fri 5/295:28 pm
DSM
- ILM
2 stops24h 05m
Delta
Deal found 4/22![Delta logo]()
$452
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:41 am
ILM
- DSM
1 stop7h 30m
American Airlines
Sun 5/106:00 am
DSM
- ILM
2 stops7h 13m
American Airlines
Deal found 4/21![American Airlines logo]()
$473
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:50 pm
ILM
- DSM
1 stop5h 44m
Delta
Sun 5/105:27 am
DSM
- ILM
1 stop7h 09m
Delta
Deal found 4/21![Delta logo]()
$468
Last-minute flights from Wilmington to Des MoinesDiscover last-minute flight deals from Wilmington to Des Moines. Data last updated April 24, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Des Moines. Data last updated April 24, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
ILM
- DSM
2 stops9h 25m
United Airlines
Sat 4/251:10 pm
DSM
- ILM
2 stops9h 34m
United Airlines
Deal found 4/20![United Airlines logo]()
$463
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:00 am
ILM
- DSM
2 stops15h 16m
United Airlines
Tue 5/1211:31 am
DSM
- ILM
2 stops11h 13m
United Airlines
Deal found 4/23![United Airlines logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:20 pm
ILM
- DSM
1 stop24h 52m
Multiple Airlines
Thu 5/284:41 pm
DSM
- ILM
2 stops26h 28m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:50 am
ILM
- DSM
1 stop6h 20m
American Airlines
Sat 5/231:37 pm
DSM
- ILM
1 stop7h 14m
American Airlines
Deal found 4/22![American Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:18 pm
ILM
- DSM
1 stop5h 14m
Delta
Sun 5/249:04 am
DSM
- ILM
1 stop7h 29m
Delta
Deal found 4/20![Delta logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:39 pm
ILM
- DSM
1 stop8h 45m
Multiple Airlines
Mon 5/253:57 pm
DSM
- ILM
2 stops18h 11m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$373
This KAYAK deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:27 pm
ILM
- DSM
1 stop5h 05m
Delta
Fri 5/295:28 pm
DSM
- ILM
2 stops24h 05m
Delta
Deal found 4/22![Delta logo]()
$452
One-way flights from Wilmington to Des MoinesSearch for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
Search for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 24, 2026.
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:50 pm
ILM
- DSM
1 stop8h 09m
American Airlines
Deal found 4/24![American Airlines logo]()
$382
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
ILM
- DSM
3 stops13h 05m
United Airlines
Deal found 4/24![United Airlines logo]()
$620
Find flight deals from Wilmington to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $330 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $394 |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Sat 8/22
7:38 am-12:34 pm
1 stop5h 56m
Des Moines
Mon 8/24
8:10 am-1:22 pm
1 stop4h 12m
$371
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Thu 5/21
7:50 am-1:10 pm
1 stop6h 20m
Des Moines
Sat 5/23
1:37 pm-9:51 pm
1 stop7h 14m
$371
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Thu 5/21
6:18 pm-10:32 pm
1 stop5h 14m
Des Moines
Sun 5/24
9:04 am-5:33 pm
1 stop7h 29m
$431
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 6/17
5:48 am-10:43 am
1 stop5h 55m
Des Moines
Sun 6/21
6:43 am-2:30 pm
1 stop6h 47m
$435
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 5/27
6:27 pm-10:32 pm
1 stop5h 05m
Des Moines
Fri 5/29
5:28 pm-6:33 pm
2 stops24h 05m
$452
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Fri 5/8
6:00 am-8:16 pm
2 stops15h 16m
Des Moines
Tue 5/12
8:00 am-11:44 pm
3 stops14h 44m
$465
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 5/6
5:50 pm-10:34 pm
1 stop5h 44m
Des Moines
Sun 5/10
5:27 am-1:36 pm
1 stop7h 09m
$468
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 5/6
6:41 am-1:11 pm
1 stop7h 30m
Des Moines
Sun 5/10
6:00 am-2:13 pm
2 stops7h 13m
$473
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Thu 6/18
8:20 pm-10:37 pm
1 stop27h 17m
Des Moines
Sun 6/21
9:27 am-8:42 pm
1 stop10h 15m
$490
Cheapest one-way
Quickest one-way
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Sat 5/2
4:50 pm-11:59 pm
1 stop8h 09m
$382
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Wilmington to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
ILM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Wilmington to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Crew
7.9
Boarding
7.5
Entertainment
6.9
Food
6.4
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Comfort
7.2
Crew
7.9
Boarding
7.5
Entertainment
6.9
Food
6.4
Overall
7.1
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Wilmington and Des Moines flights
Browse other Wilmington and Des Moines flight options. Last updated on April 24, 2026.
Other flights from Wilmington
Browse through other flights departing from Wilmington. Flights are based on user searches made on Cheapflights and were last updated on April 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Wilmington to Des Moines
Discover the top airline that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$342 | FlexibilityNo cancel fee | On-time71% |