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Des Moines

$372+ Cheap flights from Wilmington to Des Moines (ILM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
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Cheap flight deals from Wilmington to Des Moines

Cheapest flights from Wilmington to Des Moines
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:39 pm
ILM
-
DSM
1 stop8h 48m
Multiple Airlines
Sun 6/75:02 pm
DSM
-
ILM
2 stops26h 07m
Multiple Airlines
Deal found 3/27$386
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 am
ILM
-
DSM
1 stop5h 26m
American Airlines
Tue 5/197:11 am
DSM
-
ILM
1 stop8h 31m
American Airlines
Deal found 3/28$411
This United Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
ILM
-
DSM
2 stops11h 15m
United Airlines
Sat 5/211:40 am
DSM
-
ILM
2 stops11h 04m
United Airlines
Deal found 3/28$416
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
ILM
-
DSM
2 stops9h 25m
United Airlines
Sat 4/188:04 am
DSM
-
ILM
2 stops7h 32m
United Airlines
Deal found 3/25$429
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:35 pm
ILM
-
DSM
1 stop8h 22m
American Airlines
Sun 5/318:02 pm
DSM
-
ILM
1 stop14h 47m
American Airlines
Deal found 3/30$479

Find flight deals from Wilmington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$386
(Kiwi.com)

One-way from

$372
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$529
Provider with most accurate pricing for Wilmington New Hanover County-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Wilmington New Hanover County-Des Moines flights.
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From Wilmington New Hanover County to Des Moines
Search Deals
One-way flight from Wilmington New Hanover County to Des Moines
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in March 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 6/5

3:39 pm-11:27 pm

1 stop8h 48m

Des Moines

Sun 6/7

5:02 pm-8:09 pm

2 stops26h 07m

$386

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 5/15

6:00 am-10:26 am

1 stop5h 26m

Des Moines

Tue 5/19

7:11 am-4:42 pm

1 stop8h 31m

$411

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Wed 4/15

6:00 am-2:25 pm

2 stops9h 25m

Des Moines

Sat 4/18

8:04 am-4:36 pm

2 stops7h 32m

$429

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Sat 4/25

6:00 am-2:28 pm

2 stops9h 28m

Des Moines

Sat 5/2

8:00 am-11:44 pm

3 stops14h 44m

$445

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Wed 5/27

8:01 pm-12:17 am

1 stop5h 16m

Des Moines

Sun 5/31

8:02 pm-11:49 am

1 stop14h 47m

$479
Quickest round-trip

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 6/5

7:02 am-12:52 pm

1 stop6h 50m

Des Moines

Sun 6/7

1:37 pm-7:16 pm

1 stop4h 39m

$507
Cheapest one-way
Quickest one-way

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Tue 4/14

5:27 pm-9:15 pm

1 stop4h 48m

$372

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Tue 4/14

6:00 am-9:32 pm

3 stops16h 32m

$554

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Sorted by cheapest first

Compare providers for flights from Wilmington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 30, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,531 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,531 reviews
American Airlines
7.1
Good
11,531 reviews

Comfort

7.2

Entertainment

6.9

Boarding

7.5

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Des Moines?

    Departing from Wilmington to Des Moines will take you 5h 26m. The distance from Wilmington to Des Moines is about 992 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Wilmington to Des Moines round-trip?

    American Airlines, at $258, was found to be the cheapest airline from Wilmington to Des Moines.. Users have found that American Airlines is 28% cheaper than the other options available to this destination.

  • Can I find deals for flights from Wilmington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wilmington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Des Moines.

  • Can I find deals for business class flights from Wilmington to Des Moines?

    Yes. Cheapflights offers flight deals from Wilmington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ames
Clive
Ankeny
Boone
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Wilmington to Des Moines

Discover the top airline that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$342FlexibilityNo cancel feeOn-time71%

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