$359+ Cheap flights from Wilmington to Des Moines (ILM - DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
Dec 10 — Dec 171
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Wilmington to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wilmington to Des Moines
Cheapest
Best
Last-minute
Cheapest flights from Wilmington to Des MoinesExplore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:27 pm -
1 stop4h 41m
Thu 1/75:23 pm -
1 stop4h 53m
Deal found 11/6![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:09 am -
1 stop4h 39m
Fri 11/276:00 am -
1 stop4h 41m
Deal found 11/8![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
2 stops9h 09m
Thu 1/712:52 pm -
2 stops10h 06m
Deal found 11/6![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:13 pm -
1 stop6h 49m
Tue 12/157:14 am -
2 stops10h 22m
Deal found 11/10![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:19 pm -
1 stop7h 11m
Thu 1/710:26 am -
2 stops10h 13m
Deal found 11/6![American Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:12 am -
1 stop5h 01m
Wed 12/306:43 pm -
1 stop4h 16m
Deal found 11/9![Delta logo]()
$618
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:28 pm -
2 stops7h 45m
Fri 11/275:30 am -
1 stop5h 29m
Deal found 11/8![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:05 am -
2 stops31h 34m
Tue 12/158:00 am -
2 stops14h 44m
Deal found 11/10![United Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:59 pm -
2 stops7h 10m
Wed 12/305:30 am -
2 stops7h 46m
Deal found 11/9![American Airlines logo]()
$912
Best flights from Wilmington to Des MoinesDiscover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:27 pm -
1 stop4h 41m
Thu 1/75:23 pm -
1 stop4h 53m
Deal found 11/6![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:05 pm -
1 stop4h 58m
Tue 1/268:07 am -
1 stop5h 50m
Deal found 11/9![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
2 stops9h 09m
Thu 1/712:52 pm -
2 stops10h 06m
Deal found 11/6![United Airlines logo]()
$426
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2112:20 pm -
2 stops11h 54m
Mon 1/2512:52 pm -
2 stops10h 06m
Deal found 11/10![United Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:19 pm -
1 stop7h 11m
Thu 1/710:26 am -
2 stops10h 13m
Deal found 11/6![American Airlines logo]()
$498
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:00 am -
2 stops9h 30m
Tue 1/268:00 am -
3 stops14h 58m
Deal found 11/9![United Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:12 am -
1 stop5h 01m
Wed 12/306:43 pm -
1 stop4h 16m
Deal found 11/9![Delta logo]()
$618
Last-minute flights from Wilmington to Des MoinesDiscover last-minute flight deals from Wilmington to Des Moines. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Des Moines. Data last updated November 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:09 am -
1 stop4h 39m
Fri 11/276:00 am -
1 stop4h 41m
Deal found 11/8![American Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/232:28 pm -
2 stops7h 45m
Fri 11/275:30 am -
1 stop5h 29m
Deal found 11/8![Delta logo]()
$637
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:27 pm -
1 stop4h 41m
Thu 1/75:23 pm -
1 stop4h 53m
Deal found 11/6![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
2 stops9h 09m
Thu 1/712:52 pm -
2 stops10h 06m
Deal found 11/6![United Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:19 pm -
1 stop7h 11m
Thu 1/710:26 am -
2 stops10h 13m
Deal found 11/6![American Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:13 pm -
1 stop6h 49m
Tue 12/157:14 am -
2 stops10h 22m
Deal found 11/10![American Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:05 am -
2 stops31h 34m
Tue 12/158:00 am -
2 stops14h 44m
Deal found 11/10![United Airlines logo]()
$668
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:12 am -
1 stop5h 01m
Wed 12/306:43 pm -
1 stop4h 16m
Deal found 11/9![Delta logo]()
$618
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:59 pm -
2 stops7h 10m
Wed 12/305:30 am -
2 stops7h 46m
Deal found 11/9![American Airlines logo]()
$912
Find flight deals from Wilmington to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $359 (Delta) |
Popular in | July |
Cheapest in | January |
Average price | $589 |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 12/9
2:27 pm-6:08 pm
1 stop4h 41m
Des Moines
Thu 1/7
5:23 pm-11:16 pm
1 stop4h 53m
$359
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 1/20
7:05 pm-11:03 pm
1 stop4h 58m
Des Moines
Tue 1/26
8:07 am-2:57 pm
1 stop5h 50m
$359
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 12/9
6:05 am-2:14 pm
2 stops9h 09m
Des Moines
Thu 1/7
12:52 pm-11:58 pm
2 stops10h 06m
$426
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Thu 1/21
12:20 pm-11:14 pm
2 stops11h 54m
Des Moines
Mon 1/25
12:52 pm-11:58 pm
2 stops10h 06m
$469
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 1/20
6:00 am-2:30 pm
2 stops9h 30m
Des Moines
Tue 1/26
8:00 am-11:58 pm
3 stops14h 58m
$475
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 12/9
5:19 pm-11:30 pm
1 stop7h 11m
Des Moines
Thu 1/7
10:26 am-9:39 pm
2 stops10h 13m
$498
Quickest round-trip
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Fri 12/18
10:12 am-2:13 pm
1 stop5h 01m
Des Moines
Wed 12/30
6:43 pm-11:59 pm
1 stop4h 16m
$618
Sorted by cheapest first
Compare providers for flights from Wilmington to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
ILM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 10, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Entertainment
6.8
Comfort
7.1
Overall
7.0
Boarding
7.4
Food
6.4
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Crew
7.9
Entertainment
6.8
Comfort
7.1
Overall
7.0
Boarding
7.4
Food
6.4
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Wilmington
Popular flights
Alternative routes for Wilmington to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.
Search flights from Wilmington to Des Moines by cabin class
Find flights from Wilmington to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Wilmington and Des Moines flights
Browse other Wilmington and Des Moines flight options. Last updated on November 10, 2026.
Other flights from Wilmington
Browse through other flights departing from Wilmington. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Wilmington to Des Moines
Discover the top airline that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$452 | FlexibilityNo cancel fee | On-time71% |