$149+ Cheap flights from Wilmington to Des Moines (ILM - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Wilmington to Des Moines with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Wilmington to Des MoinesExplore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:25 am
ILM
- DSM
1 stop8h 50m
Delta
Sun 7/267:05 am
DSM
- ILM
1 stop6h 25m
Delta
Deal found 4/8![Delta logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:01 pm
ILM
- DSM
2 stops30h 41m
Multiple Airlines
Mon 4/276:00 am
DSM
- ILM
1 stop14h 27m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:16 pm
ILM
- DSM
1 stop5h 02m
American Airlines
Mon 4/271:25 pm
DSM
- ILM
1 stop4h 53m
American Airlines
Deal found 4/8![American Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
ILM
- DSM
2 stops9h 25m
United Airlines
Mon 4/278:04 am
DSM
- ILM
3 stops14h 40m
United Airlines
Deal found 4/8![United Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
ILM
- DSM
2 stops11h 15m
United Airlines
Sat 4/185:30 am
DSM
- ILM
2 stops10h 06m
United Airlines
Deal found 4/4![United Airlines logo]()
$478
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
ILM
- DSM
1 stop5h 26m
American Airlines
Mon 4/133:20 pm
DSM
- ILM
1 stop6h 33m
American Airlines
Deal found 4/7![American Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:02 am
ILM
- DSM
2 stops7h 07m
American Airlines
Sun 7/261:41 pm
DSM
- ILM
1 stop4h 34m
American Airlines
Deal found 4/8![American Airlines logo]()
$541
Best flights from Wilmington to Des MoinesDiscover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1511:25 am
ILM
- DSM
1 stop8h 50m
Delta
Sun 7/267:05 am
DSM
- ILM
1 stop6h 25m
Delta
Deal found 4/8![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:01 pm
ILM
- DSM
2 stops8h 38m
United Airlines
Tue 5/128:00 am
DSM
- ILM
3 stops14h 44m
United Airlines
Deal found 4/8![United Airlines logo]()
$663
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
ILM
- DSM
2 stops9h 25m
United Airlines
Sun 4/267:16 pm
DSM
- ILM
2 stops27h 28m
United Airlines
Deal found 4/7![United Airlines logo]()
$692
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
ILM
- DSM
2 stops9h 24m
United Airlines
Wed 5/136:15 am
DSM
- ILM
2 stops8h 08m
United Airlines
Deal found 4/8![United Airlines logo]()
$698
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:50 pm
ILM
- DSM
1 stop5h 44m
Delta
Wed 4/226:31 pm
DSM
- ILM
1 stop4h 28m
Delta
Deal found 4/7![Delta logo]()
$799
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:00 am
ILM
- DSM
3 stops29h 37m
United Airlines
Sun 5/108:15 am
DSM
- ILM
2 stops14h 29m
United Airlines
Deal found 4/5![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:30 am
ILM
- DSM
2 stops14h 00m
United Airlines
Sun 5/315:17 pm
DSM
- ILM
2 stops21h 07m
United Airlines
Deal found 4/7![United Airlines logo]()
$788
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
ILM
- DSM
2 stops9h 24m
United Airlines
Tue 5/127:05 pm
DSM
- ILM
2 stops27h 39m
United Airlines
Deal found 4/8![United Airlines logo]()
$883
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
ILM
- DSM
2 stops9h 25m
United Airlines
Wed 4/228:04 am
DSM
- ILM
3 stops14h 40m
United Airlines
Deal found 4/7![United Airlines logo]()
$915
Last-minute flights from Wilmington to Des MoinesDiscover last-minute flight deals from Wilmington to Des Moines. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Des Moines. Data last updated April 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
ILM
- DSM
1 stop5h 26m
American Airlines
Mon 4/133:20 pm
DSM
- ILM
1 stop6h 33m
American Airlines
Deal found 4/7![American Airlines logo]()
$529
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
ILM
- DSM
2 stops11h 15m
United Airlines
Sat 4/185:30 am
DSM
- ILM
2 stops10h 06m
United Airlines
Deal found 4/4![United Airlines logo]()
$478
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:01 pm
ILM
- DSM
2 stops30h 41m
Multiple Airlines
Mon 4/276:00 am
DSM
- ILM
1 stop14h 27m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$418
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:16 pm
ILM
- DSM
1 stop5h 02m
American Airlines
Mon 4/271:25 pm
DSM
- ILM
1 stop4h 53m
American Airlines
Deal found 4/8![American Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
ILM
- DSM
2 stops9h 25m
United Airlines
Mon 4/278:04 am
DSM
- ILM
3 stops14h 40m
United Airlines
Deal found 4/8![United Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
ILM
- DSM
1 stop14h 33m
American Airlines
Wed 5/132:24 pm
DSM
- ILM
1 stop8h 42m
American Airlines
Deal found 4/8![American Airlines logo]()
$605
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:05 pm
ILM
- DSM
1 stop8h 11m
United Airlines
Sun 5/318:15 pm
DSM
- ILM
1 stop18h 09m
United Airlines
Deal found 4/7![United Airlines logo]()
$614
One-way flights from Wilmington to Des MoinesSearch for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:20 pm
ILM
- DSM
1 stop13h 54m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$149
This deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/94:05 pm
ILM
- DSM
1 stop6h 35m
United Airlines
Deal found 4/6![United Airlines logo]()
$447
Find flight deals from Wilmington to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $409 (Delta) |
One-way from | $149 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $394 |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 7/15
11:25 am-7:15 pm
1 stop8h 50m
Des Moines
Sun 7/26
7:05 am-2:30 pm
1 stop6h 25m
$409
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Mon 5/11
5:01 pm-12:39 am
2 stops8h 38m
Des Moines
Tue 5/12
8:00 am-11:44 pm
3 stops14h 44m
$663
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 4/22
6:00 am-2:25 pm
2 stops9h 25m
Des Moines
Sun 4/26
7:16 pm-11:44 pm
2 stops27h 28m
$692
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Tue 5/12
6:00 am-2:24 pm
2 stops9h 24m
Des Moines
Wed 5/13
6:15 am-3:23 pm
2 stops8h 08m
$698
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Sun 5/3
6:00 am-10:37 am
3 stops29h 37m
Des Moines
Sun 5/10
8:15 am-11:44 pm
2 stops14h 29m
$770
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Wed 5/27
7:30 am-8:30 pm
2 stops14h 00m
Des Moines
Sun 5/31
5:17 pm-3:24 pm
2 stops21h 07m
$788
Quickest round-trip
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Mon 4/20
5:50 pm-10:34 pm
1 stop5h 44m
Des Moines
Wed 4/22
6:31 pm-11:59 pm
1 stop4h 28m
$799
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Tue 5/12
6:00 am-2:24 pm
2 stops9h 24m
Des Moines
Tue 5/12
7:05 pm-11:44 pm
2 stops27h 39m
$883
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Mon 4/20
6:00 am-2:25 pm
2 stops9h 25m
Des Moines
Wed 4/22
8:04 am-11:44 pm
3 stops14h 40m
$915
Cheapest one-way
WilmingtonDes Moines
ILM - DSM
ILMDSM
Wilmington New Hanover County
Thu 8/20
4:30 pm-6:48 pm
3 stops27h 18m
$288
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Wilmington to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
ILM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated April 9, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Boarding
7.5
Food
6.4
Overall
7.1
Entertainment
6.9
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Crew
7.9
Boarding
7.5
Food
6.4
Overall
7.1
Entertainment
6.9
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Ankeny
Boone
West Des Moines
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Other flights to Des Moines
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Wilmington and Des Moines flights
Browse other Wilmington and Des Moines flight options. Last updated on April 9, 2026.
Other flights from Wilmington
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Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Wilmington to Des Moines
Discover the top airline that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$328 | FlexibilityNo cancel fee | On-time71% |