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Des Moines

$199+ Cheap flights from Wilmington to Des Moines (ILM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
Mar 29 — Apr 51
Sun 3/29
Sun 4/5
1 adult, Economy
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Cheap flight deals from Wilmington to Des Moines

Cheapest flights from Wilmington to Des Moines
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.

This American Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
ILM
-
DSM
1 stop5h 26m
American Airlines
Wed 4/292:02 pm
DSM
-
ILM
1 stop6h 53m
American Airlines
Deal found 2/25$271
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:35 am
ILM
-
DSM
1 stop5h 42m
American Airlines
Tue 9/87:07 am
DSM
-
ILM
1 stop4h 05m
American Airlines
Deal found 2/26$300
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:24 pm
ILM
-
DSM
1 stop6h 35m
American Airlines
Tue 3/172:00 pm
DSM
-
ILM
1 stop6h 35m
American Airlines
Deal found 2/26$369
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:30 am
ILM
-
DSM
2 stops7h 41m
United Airlines
Tue 9/811:30 am
DSM
-
ILM
2 stops11h 20m
United Airlines
Deal found 2/26$397
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
ILM
-
DSM
2 stops12h 47m
United Airlines
Tue 3/39:04 am
DSM
-
ILM
2 stops13h 53m
United Airlines
Deal found 2/23$463
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:09 pm
ILM
-
DSM
1 stop22h 56m
United Airlines
Wed 9/25:50 am
DSM
-
ILM
2 stops8h 38m
United Airlines
Deal found 2/26$512
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:30 am
ILM
-
DSM
1 stop9h 26m
American Airlines
Sun 3/221:52 pm
DSM
-
ILM
1 stop7h 03m
American Airlines
Deal found 2/26$530

Find flight deals from Wilmington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(American Airlines)

One-way from

$199
(Kiwi.com)

Popular in

November

Cheapest in

August
Provider with most accurate pricing for Wilmington New Hanover County-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Des Moines flights.
Search Deals
From Wilmington New Hanover County to Des Moines
Search Deals
One-way flight from Wilmington New Hanover County to Des Moines
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($18 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Sat 4/25

6:00 am-10:26 am

1 stop5h 26m

Des Moines

Wed 4/29

2:02 pm-9:55 pm

1 stop6h 53m

$271

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 3/13

5:11 pm-11:42 pm

1 stop7h 31m

Des Moines

Tue 3/17

1:37 pm-10:56 pm

2 stops8h 19m

$374

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Thu 3/19

6:30 am-2:56 pm

1 stop9h 26m

Des Moines

Sun 3/22

1:52 pm-9:55 pm

1 stop7h 03m

$530

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Fri 3/13

6:00 am-9:40 pm

3 stops16h 40m

Des Moines

Tue 3/17

8:00 am-10:13 pm

3 stops13h 13m

$923

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Mon 3/23

3:50 pm-7:16 pm

3 stops52h 26m

$264

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Mon 3/16

10:07 pm-7:16 pm

3 stops46h 09m

$276

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Tue 3/17

6:00 am-1:23 pm

2 stops8h 23m

$289

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Mon 3/23

5:11 pm-11:42 pm

1 stop7h 31m

$330

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Sun 3/15

2:25 pm-7:16 pm

2 stops29h 51m

$332

WilmingtonDes Moines

ILM - DSM

ILMDSM

Wilmington New Hanover County

Sat 3/14

6:14 pm-9:59 pm

1 stop4h 45m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/25

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Wilmington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 27, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,242 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,242 reviews
Delta
7.9
Good
8,242 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,357 reviews
Delta
7.9
Good
8,242 reviews

Crew

8.5

Boarding

8.1

Food

7.2

Comfort

7.9

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Des Moines?

    Departing from Wilmington to Des Moines will take you 5h 26m. The distance from Wilmington to Des Moines is about 992 mi.

  • What are the cheapest airlines flying from Wilmington to Des Moines round-trip?

    Delta, at $238, was found to be the cheapest airline from Wilmington to Des Moines. An alternate airline flying to your destination would be American Airlines. Users have found that Delta is 32% cheaper than the other options available to this destination.

  • Can I find deals for flights from Wilmington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Wilmington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Des Moines.

  • Can I find deals for business class flights from Wilmington to Des Moines?

    Yes. Cheapflights offers flight deals from Wilmington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Boone
Ames
Clive
West Des Moines

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Top 2 airlines flying from Wilmington to Des Moines

Discover the top 2 airlines that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$238Average$333FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$264Average$428FlexibilityNo cancel feeOn-time71%

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