$280+ Cheap flights from Wilmington to Des Moines (ILM - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — DSM
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from Wilmington to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wilmington to Des Moines
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One-way
Cheapest flights from Wilmington to Des MoinesExplore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Wilmington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:37 pm -
1 stop6h 47m
Sat 10/107:05 am -
1 stop5h 55m
Deal found 8/3![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:07 pm -
1 stop6h 28m
Fri 9/1110:35 am -
1 stop5h 27m
Deal found 8/3![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
2 stops9h 15m
Sat 10/1011:27 am -
2 stops10h 32m
Deal found 8/3![United Airlines logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:37 pm -
1 stop6h 31m
Sun 9/131:58 pm -
2 stops30h 15m
Deal found 8/4![Multiple Airlines logo]()
$391
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:44 pm -
1 stop5h 39m
Tue 8/2511:32 am -
2 stops11h 25m
Deal found 8/6![United Airlines logo]()
$396
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:25 pm -
1 stop5h 23m
Sun 9/133:01 pm -
1 stop6h 55m
Deal found 8/4![American Airlines logo]()
$397
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:44 pm -
1 stop5h 39m
Wed 9/98:00 am -
1 stop6h 41m
Deal found 8/3![United Airlines logo]()
$405
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:44 pm -
1 stop5h 39m
Tue 9/18:00 am -
1 stop6h 37m
Deal found 8/3![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
2 stops9h 19m
Sat 11/141:05 pm -
2 stops9h 39m
Deal found 8/6![United Airlines logo]()
$411
This KAYAK deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:50 pm -
1 stop4h 54m
Fri 9/117:58 pm -
1 stop14h 55m
Deal found 8/7![American Airlines logo]()
$413
Best flights from Wilmington to Des MoinesDiscover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Wilmington to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:07 pm -
1 stop6h 28m
Fri 9/1110:35 am -
1 stop5h 27m
Deal found 8/3![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:44 pm -
1 stop5h 39m
Tue 8/2511:32 am -
2 stops11h 25m
Deal found 8/6![United Airlines logo]()
$396
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:00 am -
1 stop5h 43m
Tue 8/255:40 am -
1 stop7h 03m
Deal found 8/6![Delta logo]()
$505
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:44 pm -
1 stop5h 39m
Tue 9/18:00 am -
1 stop6h 37m
Deal found 8/4![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
2 stops9h 19m
Sat 11/141:05 pm -
2 stops9h 39m
Deal found 8/6![United Airlines logo]()
$411
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:44 pm -
1 stop5h 39m
Wed 9/98:00 am -
3 stops14h 57m
Deal found 8/3![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm -
1 stop8h 44m
Fri 9/118:00 am -
3 stops14h 57m
Deal found 8/3![United Airlines logo]()
$473
Last-minute flights from Wilmington to Des MoinesDiscover last-minute flight deals from Wilmington to Des Moines. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Des Moines. Data last updated August 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:44 pm -
1 stop5h 39m
Tue 8/2511:32 am -
2 stops11h 25m
Deal found 8/6![United Airlines logo]()
$396
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:44 pm -
1 stop5h 39m
Tue 9/18:00 am -
1 stop6h 37m
Deal found 8/3![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/34:44 pm -
1 stop5h 39m
Wed 9/98:00 am -
1 stop6h 41m
Deal found 8/3![United Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:07 pm -
1 stop6h 28m
Fri 9/1110:35 am -
1 stop5h 27m
Deal found 8/3![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:00 pm -
1 stop8h 44m
Fri 9/118:00 am -
3 stops14h 57m
Deal found 8/3![United Airlines logo]()
$473
This KAYAK deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:50 pm -
1 stop4h 54m
Fri 9/117:58 pm -
1 stop14h 55m
Deal found 8/7![American Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:37 pm -
1 stop6h 31m
Sun 9/131:58 pm -
2 stops30h 15m
Deal found 8/4![Multiple Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:25 pm -
1 stop5h 23m
Sun 9/133:01 pm -
1 stop6h 55m
Deal found 8/4![American Airlines logo]()
$397
One-way flights from Wilmington to Des MoinesSearch for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Wilmington to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:10 pm -
3 stops48h 27m
Deal found 8/7![Multiple Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:17 am -
1 stop7h 13m
Deal found 8/7![American Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:30 pm -
2 stops31h 44m
Deal found 8/7![Multiple Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:07 pm -
1 stop6h 28m
Deal found 8/7![American Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:00 am -
1 stop7h 25m
Deal found 8/7![American Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:00 am -
3 stops32h 14m
Deal found 8/7![United Airlines logo]()
$820
Find flight deals from Wilmington to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $321 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Wilmington to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Sat 9/5
7:07 pm-12:35 am
1 stop6h 28m
Des Moines
Fri 9/11
10:35 am-5:02 pm
1 stop5h 27m
$322
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Fri 8/21
4:44 pm-9:23 pm
1 stop5h 39m
Des Moines
Tue 8/25
11:32 am-11:57 pm
2 stops11h 25m
$396
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Sat 8/29
4:44 pm-9:23 pm
1 stop5h 39m
Des Moines
Tue 9/1
8:00 am-3:37 pm
1 stop6h 37m
$409
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Wed 11/11
6:00 am-2:19 pm
2 stops9h 19m
Des Moines
Sat 11/14
1:05 pm-11:44 pm
2 stops9h 39m
$411
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Thu 9/3
4:44 pm-9:23 pm
1 stop5h 39m
Des Moines
Wed 9/9
8:00 am-11:57 pm
3 stops14h 57m
$415
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Sat 9/5
4:00 pm-11:44 pm
1 stop8h 44m
Des Moines
Fri 9/11
8:00 am-11:57 pm
3 stops14h 57m
$473
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Fri 8/21
6:00 am-10:43 am
1 stop5h 43m
Des Moines
Tue 8/25
5:40 am-1:43 pm
1 stop7h 03m
$505
Cheapest one-way
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Mon 10/5
7:17 am-1:30 pm
1 stop7h 13m
$353
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Sun 8/16
4:30 pm-11:14 pm
2 stops31h 44m
$356
Quickest one-way
WilmingtonDes Moines
ILM Wilmington New Hanover County - DSM Des Moines
ILMDSM
Wilmington New Hanover County
Sat 8/15
7:07 pm-12:35 am
1 stop6h 28m
$387
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Wilmington to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Wilmington to Des Moines in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Wilmington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Wilmington with our price prediction graph.
ILM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 7, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Food
6.4
Overall
7.1
Crew
7.9
Entertainment
6.8
Comfort
7.2
Boarding
7.5
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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Wilmington and Des Moines flights
Browse other Wilmington and Des Moines flight options. Last updated on August 7, 2026.
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Top airline flying from Wilmington to Des Moines
Discover the top airline that operate flights from Wilmington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$295 | Average$428 | FlexibilityNo cancel fee | On-time71% |