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Des Moines

$119+ Cheap flights from San Antonio to Des Moines (SAT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from San Antonio to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$227
(Kiwi.com)

One-way from

$119
(United Airlines)

Popular in

March

Cheapest in

February

Average price

$340
Provider with most accurate pricing for San Antonio-Des Moines flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Des Moines flights.
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From San Antonio to Des Moines
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One-way flight from San Antonio to Des Moines
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:25 pmSAT - DSM
1 stop21h 54mFrontier
Mon 2/167:17 pmDSM - SAT
1 stop21h 24mFrontier
Deal found 1/5$227
This Delta deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:20 amSAT - DSM
1 stop5h 21mDelta
Tue 2/105:16 pmDSM - SAT
1 stop7h 23mDelta
Deal found 1/6$237
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/37:40 amSAT - DSM
2 stops8h 48mUnited Airlines
Tue 2/108:10 amDSM - SAT
1 stop5h 09mUnited Airlines
Deal found 1/6$242
This Southwest deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/412:25 pmSAT - DSM
2 stops6h 55mSouthwest
Wed 2/116:10 amDSM - SAT
1 stop6h 40mSouthwest
Deal found 1/7$243
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/39:30 amSAT - DSM
2 stops6h 54mAmerican Airlines
Tue 2/106:07 amDSM - SAT
2 stops8h 09mAmerican Airlines
Deal found 1/6$270
This Kiwi.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:25 pmSAT - DSM
1 stop21h 54mMultiple Airlines
Mon 2/168:38 pmDSM - SAT
2 stops27h 21mMultiple Airlines
Deal found 1/5$285
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:00 amSAT - DSM
2 stops13h 48mMultiple Airlines
Sun 2/157:27 pmDSM - SAT
1 stop24h 10mMultiple Airlines
Deal found 1/6$300
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 amSAT - DSM
2 stops13h 48mMultiple Airlines
Sun 2/223:32 pmDSM - SAT
1 stop17h 58mMultiple Airlines
Deal found 1/6$308
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:31 pmSAT - DSM
1 stop6h 37mDelta
Sun 5/312:35 pmDSM - SAT
1 stop6h 53mDelta
Deal found 1/5$312
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/141:18 pmSAT - DSM
1 stop6h 49mUnited Airlines
Wed 2/187:52 amDSM - SAT
1 stop5h 16mUnited Airlines
Deal found 1/5$323
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:00 amSAT - DSM
1 stop4h 34mAmerican Airlines
Mon 2/162:02 pmDSM - SAT
1 stop8h 53mAmerican Airlines
Deal found 1/6$338

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

San Antonio

Fly to

Des Moines

Route

Depart

Return

Price

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 2/11

9:00 am-2:33 pm

1 stop5h 33m

Des Moines

Wed 2/18

7:52 am-3:38 pm

1 stop7h 46m

$237

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 2/4

5:20 am-10:41 am

1 stop5h 21m

Des Moines

Wed 2/11

4:22 pm-9:34 pm

1 stop5h 12m

$237

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 2/3

5:20 am-10:41 am

1 stop5h 21m

Des Moines

Tue 2/10

5:16 pm-12:39 am

1 stop7h 23m

$237

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 2/4

9:50 am-2:22 pm

1 stop4h 32m

Des Moines

Wed 2/11

3:04 pm-9:15 pm

1 stop6h 11m

$237

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 2/3

7:40 am-4:28 pm

2 stops8h 48m

Des Moines

Tue 2/10

8:10 am-1:19 pm

1 stop5h 09m

$242

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 2/11

12:25 pm-9:10 pm

2 stops8h 45m

Des Moines

Wed 2/18

6:10 am-12:50 pm

1 stop6h 40m

$243

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 2/4

10:10 am-7:20 pm

2 stops9h 10m

Des Moines

Wed 2/11

3:20 pm-11:05 pm

2 stops7h 45m

$248

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Fri 2/13

6:00 am-7:48 pm

2 stops13h 48m

Des Moines

Sun 2/15

7:27 pm-7:37 pm

1 stop24h 10m

$300

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Fri 2/20

6:00 am-7:48 pm

2 stops13h 48m

Des Moines

Sun 2/22

3:32 pm-9:30 am

1 stop17h 58m

$308

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 5/5

2:31 pm-9:08 pm

1 stop6h 37m

Des Moines

Sun 5/31

2:35 pm-9:28 pm

1 stop6h 53m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/5

Showing 1-10 of 17 results
1
2

Compare providers for flights from San Antonio to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $68). Flying from San Antonio to Des Moines in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 8, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,139 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.2
Good
11,095 reviews
United Airlines
7.4
Good
9,139 reviews

Entertainment

7.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Des Moines?

    Departing from San Antonio to Des Moines will take you 5h 21m. San Antonio and Des Moines are separated by a distance of 872 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

    Currently priced at $276, American Airlines will fly you from San Antonio to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $384. American Airlines is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

    Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.

  • Can I find deals for business class flights from San Antonio to Des Moines?

    Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $68). Flying from San Antonio to Des Moines in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from San Antonio to Des Moines

Discover the top 2 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$404FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$384Average$431FlexibilityNo cancel feeOn-time69%

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