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Des Moines

$65+ Cheap flights from San Antonio to Des Moines (SAT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Feb 20 — Feb 271
Fri 2/20
Fri 2/27
1 adult, Economy
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Cheap flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:45 am
SAT
-
DSM
1 stop12h 29m
Frontier
Mon 4/68:14 pm
DSM
-
SAT
1 stop28h 05m
Frontier
Deal found 1/20$221
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:45 am
SAT
-
DSM
1 stop12h 29m
Multiple Airlines
Mon 4/69:45 pm
DSM
-
SAT
2 stops26h 34m
Multiple Airlines
Deal found 1/20$264
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:30 pm
SAT
-
DSM
1 stop7h 20m
Southwest
Wed 4/156:55 am
DSM
-
SAT
1 stop5h 00m
Southwest
Deal found 1/20$319
This Delta deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:10 am
SAT
-
DSM
1 stop5h 38m
Delta
Thu 4/25:20 pm
DSM
-
SAT
1 stop7h 18m
Delta
Deal found 1/19$364
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/144:45 pm
SAT
-
DSM
1 stop6h 58m
United Airlines
Wed 2/187:52 am
DSM
-
SAT
1 stop5h 16m
United Airlines
Deal found 1/20$387
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/76:15 am
SAT
-
DSM
2 stops14h 05m
Southwest
Wed 2/116:10 am
DSM
-
SAT
1 stop6h 40m
Southwest
Deal found 1/19$397
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:58 pm
SAT
-
DSM
1 stop4h 22m
United Airlines
Sun 2/157:52 am
DSM
-
SAT
1 stop5h 16m
United Airlines
Deal found 1/20$407
This Southwest deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:05 pm
SAT
-
DSM
2 stops7h 15m
Southwest
Mon 4/64:20 pm
DSM
-
SAT
2 stops8h 45m
Southwest
Deal found 1/20$408

Find flight deals from San Antonio to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$221
(Kiwi.com)

One-way from

$65
(Kiwi.com)

Popular in

March

Cheapest in

February

Average price

$351
Provider with most accurate pricing for San Antonio-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Des Moines flights.
Search Deals
From San Antonio to Des Moines
Search Deals
One-way flight from San Antonio to Des Moines
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

San Antonio

Fly to

Des Moines

Route

Depart

Return

Price

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Tue 3/31

1:30 pm-8:50 pm

1 stop7h 20m

Des Moines

Wed 4/15

6:55 am-11:55 am

1 stop5h 00m

$319

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 2/14

9:10 am-4:22 pm

1 stop7h 12m

Des Moines

Wed 2/18

7:52 am-3:38 pm

1 stop7h 46m

$387

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 2/7

1:20 pm-8:34 pm

1 stop7h 14m

Des Moines

Wed 2/11

8:10 am-1:19 pm

1 stop5h 09m

$392

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 2/7

5:45 am-12:40 pm

1 stop6h 55m

Des Moines

Wed 2/11

6:10 am-12:50 pm

1 stop6h 40m

$392

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 3/11

6:45 am-7:16 pm

1 stop12h 31m

$65

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 3/25

6:45 am-7:16 pm

1 stop12h 31m

$81

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 3/11

6:45 am-8:16 pm

2 stops37h 31m

$134

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sat 2/28

7:56 pm-6:42 pm

1 stop22h 46m

$137

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 3/12

2:13 pm-10:05 am

1 stop19h 52m

$141

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 3/18

5:10 am-10:48 am

1 stop5h 38m

$160

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 15 results
1
2

Compare providers for flights from San Antonio to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Des Moines flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

Currently, January is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $57). Flying from San Antonio to Des Moines in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 21, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,191 reviews
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,174 reviews
United Airlines
7.4
Good
9,191 reviews

Boarding

7.7

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Des Moines?

    Departing from San Antonio to Des Moines will take you 7h 12m. San Antonio and Des Moines are separated by a distance of 872 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

    Currently priced at $276, American Airlines will fly you from San Antonio to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $384. American Airlines is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

    Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.

  • Can I find deals for business class flights from San Antonio to Des Moines?

    Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Des Moines?

    Currently, January is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $57). Flying from San Antonio to Des Moines in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Top 2 airlines flying from San Antonio to Des Moines

Discover the top 2 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$276Average$406FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$384Average$431FlexibilityNo cancel feeOn-time69%

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