HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$84+ Cheap flights from San Antonio to Des Moines (SAT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
Aug 24 — Aug 311
Sun 8/24
Sun 8/31
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Antonio to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Antonio to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 19, 2025.

Round-trip from

$228
(FlightHub)

One-way from

$84
(FlightHub)

Popular in

December

Cheapest in

June

Average price

$444
From San Antonio to Des Moines
Search Deals
One-way flight from San Antonio to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2025.

This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/83:59 pmSAT - DSM
1 stop21h 53mFrontier
Sun 10/122:37 pmDSM - SAT
1 stop5h 04mFrontier
Deal found 8/18$228
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amSAT - DSM
1 stop8h 27mMultiple Airlines
Sun 10/123:43 pmDSM - SAT
1 stop13h 04mMultiple Airlines
Deal found 8/17$278
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:29 pmSAT - DSM
1 stop4h 59mAmerican Airlines
Mon 9/225:10 amDSM - SAT
1 stop4h 20mAmerican Airlines
Deal found 8/17$291
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/182:54 pmSAT - DSM
2 stops22h 38mMultiple Airlines
Mon 9/223:30 pmDSM - SAT
1 stop29h 22mMultiple Airlines
Deal found 8/17$304
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:00 amSAT - DSM
1 stop4h 00mAmerican Airlines
Sun 10/125:00 amDSM - SAT
1 stop4h 19mAmerican Airlines
Deal found 8/17$322
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/83:50 pmSAT - DSM
1 stop6h 00mSouthwest
Sun 10/126:10 pmDSM - SAT
2 stops6h 50mSouthwest
Deal found 8/18$327
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/194:48 pmSAT - DSM
1 stop6h 18mAmerican Airlines
Mon 9/224:09 pmDSM - SAT
1 stop5h 38mAmerican Airlines
Deal found 8/17$329
This KAYAK deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/291:35 pmSAT - DSM
1 stop7h 26mDelta
Tue 9/3010:55 amDSM - SAT
1 stop6h 20mDelta
Deal found 8/18$348
This KAYAK deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:05 amSAT - DSM
2 stops14h 15mSouthwest
Tue 9/308:25 amDSM - SAT
1 stop9h 30mSouthwest
Deal found 8/18$359

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

San Antonio

Fly to

Des Moines

Route

Depart

Return

Price

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 10/8

3:59 pm-1:52 pm

1 stop21h 53m

Des Moines

Sun 10/12

2:37 pm-7:41 pm

1 stop5h 04m

$228

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 10/8

6:00 am-2:27 pm

1 stop8h 27m

Des Moines

Sun 10/12

3:43 pm-4:47 am

1 stop13h 04m

$278

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 9/18

6:29 pm-11:28 pm

1 stop4h 59m

Des Moines

Mon 9/22

5:10 am-9:30 am

1 stop4h 20m

$291

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Thu 9/18

2:54 pm-1:32 pm

2 stops22h 38m

Des Moines

Mon 9/22

3:30 pm-8:52 pm

1 stop29h 22m

$304

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 10/8

5:00 am-9:00 am

1 stop4h 00m

Des Moines

Sun 10/12

5:00 am-9:19 am

1 stop4h 19m

$322

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Wed 10/8

3:50 pm-9:50 pm

1 stop6h 00m

Des Moines

Sun 10/12

6:10 pm-1:00 am

2 stops6h 50m

$327

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sun 10/5

8:20 pm-1:40 pm

1 stop17h 20m

$84

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Sun 10/5

9:33 pm-5:01 pm

3 stops19h 28m

$204

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Mon 9/1

6:24 pm-11:24 pm

1 stop5h 00m

$214

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

Mon 9/1

5:30 am-2:10 pm

2 stops8h 40m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 11 results
1
2

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to DSM?

Find hourly flight availability from San Antonio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 19, 2025.

One of the essential ways to save on airfare from San Antonio to Des Moines is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 40% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 19, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,922 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Des Moines?

    Departing from San Antonio to Des Moines will take you 21h 53m. San Antonio and Des Moines are separated by a distance of 872 mi.

  • What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

    Currently priced at $212, Delta will fly you from San Antonio to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $291 and $384, respectively. Delta is priced at 52% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

    Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.

  • Can I find deals for business class flights from San Antonio to Des Moines?

    Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Des Moines flights
Dallas/Fort Worth to Omaha flights
Hobby to Des Moines flights
Dallas/Fort Worth to Cedar Rapids flights
George Bush Intcntl to Des Moines flights
Hobby to Omaha flights
George Bush Intcntl to Omaha flights
Love Field to Omaha flights
Hobby to Cedar Rapids flights
Love Field to Des Moines flights
Austin to Omaha flights
George Bush Intcntl to Cedar Rapids flights
Dallas/Fort Worth to Moline flights
San Antonio to Omaha flights
Hobby to Moline flights
Austin to Cedar Rapids flights
Austin to Des Moines flights
George Bush Intcntl to Moline flights
El Paso to Omaha flights
San Antonio to Moline flights
San Antonio to Cedar Rapids flights
Corpus Christi to Cedar Rapids flights
Lubbock to Omaha flights
Hobby to La Crosse flights
McAllen to Omaha flights
Corpus Christi to Moline flights
Dallas/Fort Worth to La Crosse flights
Austin to Moline flights
El Paso to Des Moines flights
Harlingen to Omaha flights
Love Field to Cedar Rapids flights
George Bush Intcntl to La Crosse flights
Love Field to Moline flights
Dallas/Fort Worth to Sioux City flights
El Paso to Cedar Rapids flights
George Bush Intcntl to Sioux City flights
Midland to Cedar Rapids flights
Lubbock to Moline flights
Laredo to Omaha flights
Killeen to Cedar Rapids flights
Austin to Dubuque flights
El Paso to Moline flights
Corpus Christi to Sioux City flights
Austin to Waterloo flights
San Antonio to La Crosse flights
Killeen to Des Moines flights
Austin to La Crosse flights

Top 3 airlines flying from San Antonio to Des Moines

Discover the top 3 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$212Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$291Average$426FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$384Average$846FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.