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Des Moines

$157+ Cheap flights from San Antonio to Des Moines (SAT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — DSM
oct. 19 — oct. 261
dom. 10/19
dom. 10/26
1 adult, Economy
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Cheap flight deals from San Antonio to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 19, 2025.

Round-trip from

$218
(Kiwi.com)

One-way from

$157
(United Airlines)

Popular in

December

Cheapest in

June

Average price

$374
From San Antonio to Des Moines
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One-way flight from San Antonio to Des Moines
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Highest demand for flights based on searches. 19% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Antonio to Des Moines

Cheapest flights from San Antonio to Des Moines
Explore the most affordable flight options available from San Antonio to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 19, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/177:10 pmSAT - DSM
1 stop13h 19mMultiple Airlines
jue. 10/232:37 pmDSM - SAT
1 stop29h 04mMultiple Airlines
Deal found 9/18$218
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/22:54 pmSAT - DSM
1 stop17h 36mMultiple Airlines
mié. 10/82:37 pmDSM - SAT
1 stop29h 04mMultiple Airlines
Deal found 9/18$229
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/167:35 pmSAT - DSM
2 stops36h 54mMultiple Airlines
jue. 10/232:37 pmDSM - SAT
1 stop29h 04mMultiple Airlines
Deal found 9/18$246
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/153:59 pmSAT - DSM
1 stop21h 53mFrontier
mié. 10/222:37 pmDSM - SAT
1 stop20h 37mFrontier
Deal found 9/17$247
This Frontier deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/185:32 pmSAT - DSM
1 stop20h 20mFrontier
vie. 10/242:37 pmDSM - SAT
1 stop5h 04mFrontier
Deal found 9/17$256
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/157:00 amSAT - DSM
2 stops30h 52mMultiple Airlines
mié. 10/222:37 pmDSM - SAT
1 stop20h 37mMultiple Airlines
Deal found 9/17$266
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/273:22 pmSAT - DSM
1 stop22h 18mFrontier
vie. 10/32:25 pmDSM - SAT
1 stop24h 02mFrontier
Deal found 9/18$288
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/252:31 pmSAT - DSM
1 stop6h 32mDelta
mié. 10/296:39 pmDSM - SAT
1 stop5h 41mDelta
Deal found 9/18$305

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 19, 2025.
Use the filters below to find and compare flights from San Antonio to Des Moines that are best for you.

Fly from

San Antonio

Fly to

Des Moines

Route

Depart

Return

Price

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

vie. 10/17

7:10 pm-8:29 am

1 stop13h 19m

Des Moines

jue. 10/23

2:37 pm-7:41 pm

1 stop29h 04m

$218

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

jue. 10/2

2:54 pm-8:30 am

1 stop17h 36m

Des Moines

mié. 10/8

2:37 pm-7:41 pm

1 stop29h 04m

$229

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

jue. 10/16

7:35 pm-8:29 am

2 stops36h 54m

Des Moines

jue. 10/23

2:37 pm-7:41 pm

1 stop29h 04m

$246

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

mié. 10/15

7:00 am-2:27 pm

1 stop7h 27m

Des Moines

mié. 10/22

8:00 am-11:40 pm

1 stop15h 40m

$253

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

sáb. 10/18

5:32 pm-1:52 pm

1 stop20h 20m

Des Moines

vie. 10/24

2:37 pm-7:41 pm

1 stop5h 04m

$256

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

sáb. 10/25

2:31 pm-9:03 pm

1 stop6h 32m

Des Moines

mié. 10/29

2:13 pm-8:28 pm

1 stop6h 15m

$305

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

jue. 10/16

4:39 pm-11:56 pm

1 stop7h 17m

$157

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

vie. 9/26

7:25 pm-4:59 pm

2 stops45h 34m

$221

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

mar. 9/30

5:29 am-1:20 pm

1 stop7h 51m

$325

San AntonioDes Moines

SAT - DSM

SATDSM

San Antonio

mar. 9/30

3:45 pm-10:20 pm

2 stops6h 35m

$330

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/18

Showing 1-10 of 14 results
1
2

Best time to book a flight from San Antonio to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Des Moines

What is the cheapest month to book a flight from San Antonio to Des Moines?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to DSM?

Find hourly flight availability from San Antonio to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 19, 2025.

One of the essential ways to save on airfare from San Antonio to Des Moines is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 40% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated septiembre 19, 2025.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Comfort

7.3

Boarding

7.7

Overall

7.4

Crew

8.1

Entertainment

7.1

Food

6.6

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Antonio to Des Moines round-trip?

    Currently priced at $286, American Airlines will fly you from San Antonio to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $384. American Airlines is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from San Antonio to Des Moines that include hotel bookings?

    Yes. In addition to deals on San Antonio to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Des Moines.

  • Can I find deals for business class flights from San Antonio to Des Moines?

    Yes. Cheapflights offers flight deals from San Antonio to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from San Antonio to Des Moines (average of $336). Flying from San Antonio to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from San Antonio to Des Moines

Discover the top 2 airlines that operate flights from San Antonio to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$429FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$384Average$687FlexibilityNo cancel feeOn-time69%

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