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Des Moines

$319+ Cheap flights from Roanoke to Des Moines (ROA - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — DSM
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Roanoke to Des Moines

Cheapest flights from Roanoke to Des Moines
Explore the most affordable flight options available from Roanoke to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:32 amROA - DSM
2 stops8h 33mUnited Airlines
Sat 12/276:46 pmDSM - ROA
1 stop14h 30mUnited Airlines
Deal found 12/11$624
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/229:31 pmROA - DSM
1 stop17h 50mMultiple Airlines
Sat 12/278:29 pmDSM - ROA
2 stops23h 37mMultiple Airlines
Deal found 12/11$654
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:07 pmROA - DSM
1 stop6h 30mAmerican Airlines
Sat 12/276:30 amDSM - ROA
1 stop16h 36mAmerican Airlines
Deal found 12/11$710

Find flight deals from Roanoke to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$319
(United Airlines)

Popular in

March

Cheapest in

September
Provider with most accurate pricing for Roanoke-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Des Moines flights.
Search Deals
From Roanoke to Des Moines
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($20 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Roanoke to Des Moines that are best for you.

Fly from

Roanoke

Fly to

Des Moines

Route

Depart

Return

Price

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Sat 1/31

12:40 pm-5:47 pm

1 stop6h 07m

Des Moines

Tue 2/3

8:00 am-7:31 pm

2 stops10h 31m

$324

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Mon 12/22

10:32 am-6:05 pm

2 stops8h 33m

Des Moines

Sat 12/27

6:46 pm-10:16 am

1 stop14h 30m

$624

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Mon 12/22

9:31 pm-2:21 pm

1 stop17h 50m

Des Moines

Sat 12/27

8:29 pm-9:06 pm

2 stops23h 37m

$654

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Mon 12/22

7:07 pm-12:37 am

1 stop6h 30m

Des Moines

Sat 12/27

6:30 am-12:06 am

1 stop16h 36m

$710

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Sun 12/21

4:01 pm-2:21 pm

3 stops47h 20m

$322

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Sun 12/21

5:42 pm-9:40 pm

1 stop4h 58m

$390

RoanokeDes Moines

ROA - DSM

ROADSM

Roanoke

Sun 12/21

11:17 am-8:44 pm

2 stops10h 27m

$395

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Roanoke to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Des Moines in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Roanoke-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Roanoke-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Des Moines

What is the cheapest month to book a flight from Roanoke to Des Moines?

Currently, May is the cheapest month in which you can book a flight from Roanoke to Des Moines (average of $209). Flying from Roanoke to Des Moines in December is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to DSM?

Find hourly flight availability from Roanoke to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Roanoke to Des Moines in the evening. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with United Airlines and American Airlines from Roanoke to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,095 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,095 reviews
United Airlines
7.4
Good
9,095 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
American Airlines
7.2
Good
11,050 reviews
United Airlines
7.4
Good
9,095 reviews

Food

6.6

Comfort

7.3

Crew

8.1

Boarding

7.7

Entertainment

7.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Des Moines?

    Departing from Roanoke to Des Moines will take you 6h 07m. The distance from Roanoke to Des Moines is about 784 mi.

  • What are the cheapest airlines flying from Roanoke to Des Moines round-trip?

    Our cheapest airline available from Roanoke to Des Moines is United Airlines. Our recent data shows that you can find tickets from as low as $248 on this airline. An additional option worth looking into is American Airlines, starting at $283. United Airlines is priced at 39% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Roanoke to Des Moines that include hotel bookings?

    Yes. In addition to deals on Roanoke to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Des Moines.

  • Can I find deals for business class flights from Roanoke to Des Moines?

    Yes. Cheapflights offers flight deals from Roanoke to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Des Moines?

    Currently, May is the cheapest month in which you can book a flight from Roanoke to Des Moines (average of $209). Flying from Roanoke to Des Moines in December is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Top 2 airlines flying from Roanoke to Des Moines

Discover the top 2 airlines that operate flights from Roanoke to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$353FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$283Average$408FlexibilityNo cancel feeOn-time71%

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