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Des Moines

$279+ Cheap flights from Mobile to Des Moines (MOB - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — DSM
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
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Cheap flight deals from Mobile to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mobile (MOB) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(Delta)
Provider with most accurate pricing for Mobile-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mobile-Des Moines flights.
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From Mobile to Des Moines
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Find flight deals from Mobile to Des Moines

Cheapest flights from Mobile to Des Moines
Explore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/101:23 pmMOB - DSM
1 stop4h 24mDelta
Sun 12/145:34 amDSM - MOB
1 stop7h 09mDelta
Deal found 11/25$279
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:00 amMOB - DSM
2 stops9h 12mUnited Airlines
Sun 12/142:53 pmDSM - MOB
1 stop6h 54mUnited Airlines
Deal found 11/25$284
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:15 amMOB - DSM
1 stop8h 14mAmerican Airlines
Sun 11/303:31 pmDSM - MOB
1 stop7h 19mAmerican Airlines
Deal found 11/25$369
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/263:15 pmMOB - DSM
1 stop7h 05mUnited Airlines
Sun 11/305:14 pmDSM - MOB
2 stops8h 13mUnited Airlines
Deal found 11/25$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Mobile to Des Moines that are best for you.

Fly from

Mobile

Fly to

Des Moines

Route

Depart

Return

Price

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 12/10

1:23 pm-5:47 pm

1 stop4h 24m

Des Moines

Sun 12/14

5:34 am-12:43 pm

1 stop7h 09m

$279

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 12/10

7:00 am-4:12 pm

2 stops9h 12m

Des Moines

Sun 12/14

2:53 pm-9:47 pm

1 stop6h 54m

$284

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 2/14

6:00 am-12:14 pm

1 stop6h 14m

Des Moines

Wed 2/18

4:21 pm-10:58 pm

2 stops6h 37m

$309

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 2/14

4:55 pm-10:20 pm

1 stop5h 25m

Des Moines

Wed 2/18

2:59 pm-9:59 pm

1 stop7h 00m

$319

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 2/14

5:13 am-1:16 pm

1 stop8h 03m

Des Moines

Wed 2/18

3:26 pm-11:06 pm

1 stop7h 40m

$386

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Mon 1/26

4:50 pm-10:30 pm

1 stop5h 40m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Compare providers for flights from Mobile to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Mobile to Des Moines in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Mobile-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Mobile-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Mobile-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Mobile-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Mobile-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Mobile to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Des Moines

What is the cheapest month to book a flight from Mobile to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $236). Flying from Mobile to Des Moines in December is currently the most expensive (average of $709). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated November 26, 2025.
Get a feel of what it's like to fly with American Airlines from Mobile to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Entertainment

6.9

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Entertainment

6.9

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.4

Reviews

1 / 20
8.0
Excellent

Monica,Nov 2025

JAC - DFW

At least there was an option of entertainment on this flight.

Related info for your journey

Find useful and relevant information for your journey from Mobile to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mobile to Des Moines?

    There are many flights that can get you from Mobile to Des Moines in 4h 24m. Fly via Delta or United Airlines to get the fastest option. Airlines will cover a distance of 807 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Mobile to Des Moines round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Mobile to Des Moines..

  • Can I find deals for flights from Mobile to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mobile to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Des Moines.

  • Can I find deals for business class flights from Mobile to Des Moines?

    Yes. Cheapflights offers flight deals from Mobile to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $236). Flying from Mobile to Des Moines in December is currently the most expensive (average of $709). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from Mobile to Des Moines

Discover the top airline that operate flights from Mobile to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$283FlexibilityNo cancel feeOn-time71%

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