What is the cheapest airline to fly from Mobile to Des Moines round-trip?

American Airlines, at $193, was found to be the cheapest airline from Mobile to Des Moines..

What is the cheapest day to fly from Mobile to Des Moines?

Travelers seeking maximum savings on their Mobile to Des Moines flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What is the cheapest day to fly round-trip from Mobile to Des Moines?

Departing on a Friday is a good option for securing a great price. You can expect to save up to 62% when planning your travel around this day of the week.

What is the cheapest time of day to fly from MOB to DSM?

When flying from Mobile to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 14% versus a flight in the morning.

Can I find deals for flights from Mobile to Des Moines that include hotel bookings?

Yes. In addition to deals on Mobile to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mobile to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Des Moines.

Can I find deals for business class flights from Mobile to Des Moines?

Yes. Cheapflights offers flight deals from Mobile to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$279+ Flights from Mobile to Des Moines

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Cheap flight deals from Mobile to Des Moines

Round-trip from	$279 (Delta)

From Mobile to Des Moines

Search Deals

Find flight deals from Mobile to Des Moines

Cheapest flights from Mobile to Des Moines
Explore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Wed 10/229:13 amMOB - DSM

1 stop4h 15mDelta

Wed 10/296:39 pmDSM - MOB

1 stop4h 09mDelta

Deal found 8/14

$279

Wed 10/81:17 pmMOB - DSM

1 stop4h 27mDelta

Wed 10/156:39 pmDSM - MOB

1 stop4h 09mDelta

Deal found 8/13

$309

Wed 10/83:32 pmMOB - DSM

1 stop7h 44mAmerican Airlines

Wed 10/159:00 amDSM - MOB

2 stops11h 57mAmerican Airlines

Deal found 8/13

$320

Wed 10/227:00 amMOB - DSM

1 stop15h 28mUnited Airlines

Wed 10/295:45 amDSM - MOB

2 stops10h 22mUnited Airlines

Deal found 8/14

$423

Best flights from Mobile to Des Moines
Discover carefully curated flight deals from Mobile to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Wed 10/229:13 amMOB - DSM

1 stop4h 15mDelta

Wed 10/296:39 pmDSM - MOB

1 stop4h 09mDelta

Deal found 8/14

$279

Wed 10/83:32 pmMOB - DSM

1 stop7h 44mAmerican Airlines

Wed 10/159:00 amDSM - MOB

2 stops11h 57mAmerican Airlines

Deal found 8/13

$320

Wed 10/227:00 amMOB - DSM

1 stop15h 28mUnited Airlines

Wed 10/295:45 amDSM - MOB

2 stops10h 22mUnited Airlines

Deal found 8/14

$423

Wed 10/81:17 pmMOB - DSM

1 stop4h 27mDelta

Wed 10/156:39 pmDSM - MOB

1 stop4h 09mDelta

Deal found 8/13

$309

One-way flights from Mobile to Des Moines
Search for one-way flight options from Mobile to Des Moines. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Sun 11/307:00 amMOB - DSM

1 stop15h 20mUnited Airlines

Deal found 8/14

$765

Fly from

Fly to

Route

Depart

Return

Price

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 10/22

9:13 am-1:28 pm

1 stop4h 15m

Des Moines

Wed 10/29

6:39 pm-10:48 pm

1 stop4h 09m

$279

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 10/8

1:17 pm-5:44 pm

1 stop4h 27m

Des Moines

Wed 10/15

6:39 pm-10:48 pm

1 stop4h 09m

$309

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 10/8

3:32 pm-11:16 pm

1 stop7h 44m

Des Moines

Wed 10/15

9:00 am-8:57 pm

2 stops11h 57m

$320

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 10/22

7:00 am-10:28 pm

1 stop15h 28m

Des Moines

Wed 10/29

5:45 am-4:07 pm

2 stops10h 22m

$423

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sun 11/30

7:00 am-10:20 pm

1 stop15h 20m

$765

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Mobile to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mobile with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Des Moines

What is the cheapest month to book a flight from Mobile to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $336). Flying from Mobile to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with American Airlines from Mobile to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

American Airlines

7.2

Good

10,000 reviews

American Airlines

7.2

Good

10,000 reviews

Reviews

1 / 20

2.0

Mediocre

Anonymous,Aug 2025

MIA - DCA

Related info for your journey

What is the cheapest airline to fly from Mobile to Des Moines round-trip?
American Airlines, at $193, was found to be the cheapest airline from Mobile to Des Moines..
Can I find deals for flights from Mobile to Des Moines that include hotel bookings?
Yes. In addition to deals on Mobile to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mobile to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Des Moines.
Can I find deals for business class flights from Mobile to Des Moines?
Yes. Cheapflights offers flight deals from Mobile to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mobile to Des Moines?
Currently, August is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $336). Flying from Mobile to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Mobile to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$193	Average$283	FlexibilityNo cancel fee	On-time71%

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$279+ Cheap flights from Mobile to Des Moines (MOB - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mobile to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Mobile to Des Moines

Round-trip from

Find flight deals from Mobile to Des Moines

Cheapest flights from Mobile to Des MoinesExplore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mobile to Des Moines that are best for you.

Best time to book a flight from Mobile to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mobile with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Des Moines

What is the cheapest month to book a flight from Mobile to Des Moines?

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with American Airlines from Mobile to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Mobile to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What is the cheapest airline to fly from Mobile to Des Moines round-trip?

Can I find deals for flights from Mobile to Des Moines that include hotel bookings?

How can I find direct flights from Mobile to Des Moines?

Can I find deals for business class flights from Mobile to Des Moines?

What is the cheapest month to book a flight from Mobile to Des Moines?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mobile to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Mobile to Des Moines

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Mobile to Des Moines
Explore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.