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Des Moines

$234+ Cheap flights from Mobile to Des Moines (MOB - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — DSM
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Mobile to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Mobile (MOB) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$259
(Delta)

One-way from

$234
(Delta)
From Mobile to Des Moines
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One-way flight from Mobile to Des Moines
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Find flight deals from Mobile to Des Moines

Cheapest flights from Mobile to Des Moines
Explore the most affordable flight options available from Mobile to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amMOB - DSM
1 stop7h 20mDelta
Sat 10/45:12 pmDSM - MOB
1 stop6h 00mDelta
Deal found 9/14$259
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:40 amMOB - DSM
2 stops8h 44mAmerican Airlines
Sat 10/47:08 amDSM - MOB
2 stops9h 44mAmerican Airlines
Deal found 9/14$269
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:32 pmMOB - DSM
1 stop7h 24mAmerican Airlines
Sat 10/183:48 pmDSM - MOB
1 stop7h 30mAmerican Airlines
Deal found 9/14$279
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/189:20 amMOB - DSM
2 stops10h 51mUnited Airlines
Sun 10/196:15 amDSM - MOB
1 stop5h 28mUnited Airlines
Deal found 9/14$314
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:21 pmMOB - DSM
1 stop4h 55mAmerican Airlines
Sun 10/265:00 amDSM - MOB
1 stop5h 16mAmerican Airlines
Deal found 9/14$368
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/61:17 pmMOB - DSM
1 stop4h 27mDelta
Fri 11/76:39 pmDSM - MOB
1 stop4h 09mDelta
Deal found 9/14$472
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1812:50 pmMOB - DSM
2 stops9h 06mAmerican Airlines
Sun 10/195:00 amDSM - MOB
2 stops7h 25mAmerican Airlines
Deal found 9/14$587

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Mobile to Des Moines that are best for you.

Fly from

Mobile

Fly to

Des Moines

Route

Depart

Return

Price

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Tue 9/30

6:00 am-1:20 pm

1 stop7h 20m

Des Moines

Sat 10/4

5:12 pm-11:12 pm

1 stop6h 00m

$259

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Tue 9/30

6:40 am-3:24 pm

2 stops8h 44m

Des Moines

Sat 10/4

7:08 am-4:52 pm

2 stops9h 44m

$269

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 10/18

7:00 am-2:13 pm

1 stop7h 13m

Des Moines

Sun 10/19

6:15 am-11:43 am

1 stop5h 28m

$279

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Fri 10/17

3:32 pm-10:56 pm

1 stop7h 24m

Des Moines

Sat 10/18

3:48 pm-11:18 pm

1 stop7h 30m

$279

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 10/25

6:21 pm-11:16 pm

1 stop4h 55m

Des Moines

Sun 10/26

5:00 am-10:16 am

1 stop5h 16m

$368

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Thu 11/6

1:17 pm-5:44 pm

1 stop4h 27m

Des Moines

Fri 11/7

6:39 pm-10:48 pm

1 stop4h 09m

$472

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Thu 11/6

5:08 am-10:40 am

1 stop5h 32m

$234

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Sat 11/1

5:43 am-10:05 am

1 stop4h 22m

$234

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Thu 11/6

9:13 am-8:35 pm

2 stops11h 22m

$244

MobileDes Moines

MOB - DSM

MOBDSM

Mobile

Wed 10/15

7:00 am-8:18 pm

2 stops13h 18m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Mobile to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Des Moines

What is the cheapest month to book a flight from Mobile to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $336). Flying from Mobile to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with American Airlines from Mobile to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Boarding

7.5

Food

6.4

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Boarding

7.5

Food

6.4

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Mobile to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mobile to Des Moines?

    There are many flights that can get you from Mobile to Des Moines in 7h 13m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. Airlines will cover a distance of 807 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Mobile to Des Moines round-trip?

    American Airlines, at $228, was found to be the cheapest airline from Mobile to Des Moines..

  • What are the cheapest airlines to fly from Mobile to Des Moines one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $234. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Mobile to Des Moines for a low price.

  • Can I find deals for flights from Mobile to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mobile to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Des Moines.

  • Can I find deals for business class flights from Mobile to Des Moines?

    Yes. Cheapflights offers flight deals from Mobile to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mobile to Des Moines (average of $336). Flying from Mobile to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from Mobile to Des Moines

Discover the top airline that operate flights from Mobile to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$283FlexibilityNo cancel feeOn-time71%

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