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Des Moines

$244+ Cheap flights from Melbourne, FL to Des Moines (MLB - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
MLB — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Melbourne to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Melbourne (MLB) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$443
(American Airlines)

One-way from

$244
(Delta)

Popular in

November

Cheapest in

April

Average price

$286
From Melbourne to Des Moines
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One-way flight from Melbourne to Des Moines
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Highest demand for flights based on searches. 18% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Melbourne to Des Moines

Cheapest flights from Melbourne to Des Moines
Explore the most affordable flight options available from Melbourne to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/91:42 pmMLB - DSM
1 stop5h 00mAmerican Airlines
Thu 10/1611:21 amDSM - MLB
1 stop6h 20mAmerican Airlines
Deal found 9/11$443
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:46 pmMLB - DSM
1 stop4h 51mDelta
Fri 10/311:25 amDSM - MLB
1 stop5h 22mDelta
Deal found 9/10$507
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/242:45 pmMLB - DSM
2 stops10h 14mAmerican Airlines
Mon 10/277:06 amDSM - MLB
2 stops10h 35mAmerican Airlines
Deal found 9/10$604

Cheapflights Fare Finder

 
Customize your flight search to find flights from Melbourne to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Melbourne to Des Moines that are best for you.

Fly from

Melbourne

Fly to

Des Moines

Route

Depart

Return

Price

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Thu 10/9

1:42 pm-5:42 pm

1 stop5h 00m

Des Moines

Thu 10/16

11:21 am-6:41 pm

1 stop6h 20m

$443

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 9/26

6:46 pm-10:37 pm

1 stop4h 51m

Des Moines

Fri 10/3

11:25 am-5:47 pm

1 stop5h 22m

$507

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Fri 10/24

2:45 pm-11:59 pm

2 stops10h 14m

Des Moines

Mon 10/27

7:06 am-6:41 pm

2 stops10h 35m

$604

MelbourneDes Moines

MLB - DSM

MLBDSM

Melbourne

Tue 3/3

5:55 am-10:23 am

1 stop5h 28m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Melbourne to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Melbourne with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Melbourne to Des Moines

What is the cheapest month to book a flight from Melbourne, Florida to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Melbourne, Florida to Des Moines (average of $336). Flying from Melbourne, Florida to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Melbourne to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Melbourne, Florida to Des Moines?

    American Airlines and Delta can get you from Melbourne, Florida to Des Moines in just under 4h 51m. Your travel time can differ by up to 09m. There are 1182 mi between Melbourne, Florida and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Melbourne to Des Moines that include hotel bookings?

    Yes. In addition to deals on Melbourne to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Melbourne to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Melbourne to Des Moines.

  • Can I find deals for business class flights from Melbourne to Des Moines?

    Yes. Cheapflights offers flight deals from Melbourne to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Melbourne, Florida to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Melbourne, Florida to Des Moines (average of $336). Flying from Melbourne, Florida to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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