$134+ Cheap flights from Maine to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — DSM
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Maine to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Maine to Des Moines
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Best
Last-minute
One-way
Cheapest flights from Maine to Des MoinesExplore the most affordable flight options available from Maine to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Maine to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop9h 13m
Tue 1/56:20 am -
1 stop4h 33m
Deal found 10/20![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:08 pm -
1 stop6h 51m
Mon 11/95:30 am -
1 stop9h 32m
Deal found 10/20![United Airlines logo]()
$412
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop9h 13m
Sun 1/37:30 am -
1 stop7h 20m
Deal found 10/20![Delta logo]()
$458
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:38 pm -
1 stop5h 07m
Tue 1/56:20 am -
1 stop4h 33m
Deal found 10/20![Delta logo]()
$493
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:38 pm -
1 stop5h 07m
Sun 12/206:15 am -
1 stop5h 04m
Deal found 10/21![Delta logo]()
$514
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/193:29 pm -
1 stop8h 07m
Tue 1/56:00 am -
1 stop7h 49m
Deal found 10/20![American Airlines logo]()
$542
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:35 pm -
2 stops24h 47m
Mon 1/42:50 pm -
1 stop17h 31m
Deal found 10/20![Multiple Airlines logo]()
$546
Best flights from Maine to Des MoinesDiscover carefully curated flight deals from Maine to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Maine to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop9h 13m
Tue 1/56:20 am -
1 stop4h 33m
Deal found 10/20![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:10 am -
2 stops8h 20m
Sat 1/99:25 am -
2 stops8h 28m
Deal found 10/24![United Airlines logo]()
$475
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:15 am -
2 stops17h 35m
Sun 12/205:40 pm -
2 stops15h 10m
Deal found 10/21![Southwest logo]()
$625
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:38 pm -
1 stop5h 07m
Mon 1/410:55 am -
2 stops10h 28m
Deal found 10/21![Delta logo]()
$570
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:28 pm -
1 stop7h 49m
Tue 1/58:00 am -
3 stops12h 03m
Deal found 10/20![United Airlines logo]()
$581
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop9h 13m
Sat 1/26:15 am -
1 stop5h 04m
Deal found 10/20![Delta logo]()
$599
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:23 pm -
1 stop9h 19m
Sat 11/288:00 am -
1 stop5h 16m
Deal found 10/24![United Airlines logo]()
$663
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop9h 13m
Mon 1/47:25 am -
1 stop26h 36m
Deal found 10/20![Delta logo]()
$627
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:38 pm -
1 stop5h 07m
Sat 1/26:15 am -
1 stop5h 04m
Deal found 10/20![Delta logo]()
$699
Last-minute flights from Maine to Des MoinesDiscover last-minute flight deals from Maine to Des Moines. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Maine to Des Moines. Data last updated October 25, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:08 pm -
1 stop5h 47m
Sun 11/18:00 am -
1 stop5h 16m
Deal found 10/20![United Airlines logo]()
$675
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:00 pm -
1 stop5h 00m
Sun 11/15:25 am -
2 stops10h 05m
Deal found 10/20![Southwest logo]()
$686
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:45 pm -
1 stop7h 29m
Sun 11/15:39 am -
1 stop5h 14m
Deal found 10/20![American Airlines logo]()
$714
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:52 pm -
2 stops7h 48m
Sun 11/15:39 am -
2 stops9h 23m
Deal found 10/20![Delta logo]()
$731
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:32 am -
1 stop6h 54m
Sat 10/311:05 pm -
1 stop7h 43m
Deal found 10/20![United Airlines logo]()
$739
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:08 pm -
1 stop6h 51m
Mon 11/95:30 am -
1 stop9h 32m
Deal found 10/20![United Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:23 pm -
1 stop9h 19m
Sat 11/288:00 am -
1 stop5h 16m
Deal found 10/24![United Airlines logo]()
$663
One-way flights from Maine to Des MoinesSearch for one-way flight options from Maine to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Maine to Des Moines. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop9h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$134
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:45 pm -
2 stops10h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Southwest logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:09 pm -
3 stops28h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:38 pm -
1 stop5h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/191:00 pm -
2 stops11h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:28 pm -
1 stop7h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$345
Find flight deals from Maine to Des Moines
Keep the following information in mind while searching for Maine to Des Moines flight deals. Data was last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $343 (Delta) |
One-way from | $134 (Delta) |
Popular in | January |
Cheapest in | August |
Average price | $611 |
Cheapflights Fare Finder
Customize your flight search to find flights from Maine to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Maine to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
6:00 am-2:13 pm
1 stop9h 13m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$134
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
12:45 pm-10:05 pm
2 stops10h 20m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$139
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 11/11
5:09 pm-8:55 pm
3 stops28h 46m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$272
Quickest round-trip
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sat 12/19
4:38 pm-8:45 pm
1 stop5h 07m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$327
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sat 12/19
1:00 pm-11:00 pm
2 stops11h 00m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$336
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Fri 12/18
6:00 am-2:13 pm
1 stop9h 13m
Des Moines
Tue 1/5
6:20 am-11:53 am
1 stop4h 33m
$343
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sat 12/19
4:28 pm-11:17 pm
1 stop7h 49m
Des Moines
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$345
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Wed 1/6
7:10 am-2:30 pm
2 stops8h 20m
Des Moines
Sat 1/9
9:25 am-6:53 pm
2 stops8h 28m
$475
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sat 12/19
4:38 pm-8:45 pm
1 stop5h 07m
Des Moines
Mon 1/4
10:55 am-10:23 pm
2 stops10h 28m
$570
PortlandDes Moines
PWM Portland - DSM Des Moines
PWMDSM
Portland
Sat 12/19
4:28 pm-11:17 pm
1 stop7h 49m
Des Moines
Tue 1/5
8:00 am-9:03 pm
3 stops12h 03m
$581
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Maine to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Maine with our price prediction graph.
PWM-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Maine to Des Moines
USME-DSM
PWM-DSM
How much does it cost to fly round-trip from Maine to Des Moines?
Airfare is below average for this route at the moment.
Maine to Des Moines flights typically cost between $564 and $707 in December.The cheapest round-trip price found within the last 5 days was $343 on Delta (Dec 18-Jan 5).
Related info for your journey
Find useful and relevant information for your journey from Maine to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
West Des Moines
Ames
Johnston
Boone
Norwalk
Ankeny
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Maine to Des Moines
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 25, 2026.
Search flights from Maine to Des Moines by cabin class
Find flights from Maine to Des Moines, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Maine and Des Moines flights
Browse other Maine and Des Moines flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Maine to Des Moines flights
Consider these flights traveling from Maine to Des Moines.
Top 2 airlines flying from Maine to Des Moines
Discover the top 2 airlines that operate flights from Maine to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$280 | Average$455 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$390 | Average$539 | FlexibilityNo cancel fee | On-time69% |