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Des Moines

$608+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Madrid to Des Moines

Cheapest flights from Madrid to Des Moines
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:55 am
MAD
-
DSM
2 stops22h 45m
United Airlines
Wed 6/105:00 am
DSM
-
MAD
2 stops21h 50m
United Airlines
Deal found 2/13$907
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:25 pm
MAD
-
DSM
1 stop13h 33m
American Airlines
Wed 6/104:48 pm
DSM
-
MAD
1 stop14h 37m
American Airlines
Deal found 2/10$950
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
MAD
-
DSM
2 stops18h 06m
Delta
Wed 6/105:45 am
DSM
-
MAD
1 stop23h 30m
Delta
Deal found 2/13$963
This KLM deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/39:50 am
MAD
-
DSM
1 stop15h 03m
KLM
Wed 6/102:15 pm
DSM
-
MAD
1 stop15h 00m
KLM
Deal found 2/13$969
This Air Canada deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:30 pm
MAD
-
DSM
2 stops27h 57m
Multiple Airlines
Wed 6/106:00 am
DSM
-
MAD
3 stops17h 50m
Multiple Airlines
Deal found 2/13$993

Find flight deals from Madrid to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$907
(United Airlines)

One-way from

$608
(American Airlines)

Popular in

March

Cheapest in

September

Average price

$990
Provider with most accurate pricing for Madrid Barajas-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madrid Barajas-Des Moines flights.
Search Deals
From Madrid Barajas to Des Moines
Search Deals
One-way flight from Madrid Barajas to Des Moines
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($367 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($158 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.

Fly from

Madrid

Fly to

Des Moines

Route

Depart

Return

Price

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

5:55 am-9:40 pm

2 stops22h 45m

Des Moines

Wed 6/10

5:00 am-9:50 am

2 stops21h 50m

$907

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

3:25 pm-9:58 pm

1 stop13h 33m

Des Moines

Wed 6/10

4:48 pm-2:25 pm

1 stop14h 37m

$950

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

6:00 am-5:06 pm

2 stops18h 06m

Des Moines

Wed 6/10

5:45 am-12:15 pm

1 stop23h 30m

$963

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

9:50 am-5:53 pm

1 stop15h 03m

Des Moines

Wed 6/10

2:15 pm-12:15 pm

1 stop15h 00m

$969

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 6/3

1:30 pm-10:27 am

2 stops27h 57m

Des Moines

Wed 6/10

6:00 am-6:50 am

3 stops17h 50m

$993

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 4/6

3:55 pm-11:42 pm

1 stop14h 47m

$608

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 4/6

11:15 pm-3:42 pm

3 stops47h 27m

$649

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 4/6

7:30 am-6:19 pm

2 stops17h 49m

$798

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/10

  • Most accurate provider: When it comes to deals on Madrid-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Des Moines

What is the cheapest month to book a flight from Madrid to Des Moines?

Currently, September is the cheapest month in which you can book a flight from Madrid to Des Moines (average of $451). Flying from Madrid to Des Moines in March is currently the most expensive (average of $3,072). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Des Moines?

    Departing from Madrid to Des Moines will take you 13h 33m. Madrid and Des Moines are separated by a distance of 4457 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Madrid to Des Moines that include hotel bookings?

    Yes. In addition to deals on Madrid to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Des Moines.

  • Can I find deals for business class flights from Madrid to Des Moines?

    Yes. Cheapflights offers flight deals from Madrid to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from Madrid to Des Moines (average of $451). Flying from Madrid to Des Moines in March is currently the most expensive (average of $3,072). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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