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Des Moines

$568+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Madrid to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$841
(American Airlines)

One-way from

$568
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$804
From Madrid Barajas to Des Moines
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One-way flight from Madrid Barajas to Des Moines
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Highest demand for flights based on searches. 15% potential increase in price ($196 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($78 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Madrid to Des Moines

Cheapest flights from Madrid to Des Moines
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/271:45 pmMAD - DSM
1 stop14h 55mAmerican Airlines
Wed 10/11:40 pmDSM - MAD
1 stop12h 55mAmerican Airlines
Deal found 9/11$841
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/251:00 pmMAD - DSM
1 stop16h 28mAmerican Airlines
Sat 11/11:55 pmDSM - MAD
1 stop13h 00mAmerican Airlines
Deal found 9/10$847
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMAD - DSM
2 stops22h 32mUnited Airlines
Mon 11/106:50 pmDSM - MAD
2 stops30h 10mUnited Airlines
Deal found 9/9$853
This Iberia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:35 amMAD - DSM
1 stop19h 15mIberia
Mon 11/102:19 pmDSM - MAD
1 stop10h 36mIberia
Deal found 9/10$858
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:35 pmMAD - DSM
2 stops28h 07mMultiple Airlines
Thu 11/278:02 amDSM - MAD
3 stops16h 58mMultiple Airlines
Deal found 9/11$871
This Air Canada deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:35 pmMAD - DSM
3 stops28h 07mAir Canada
Thu 11/278:02 amDSM - MAD
3 stops16h 58mAir Canada
Deal found 9/11$877
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amMAD - DSM
2 stops18h 12mKLM
Thu 11/271:10 pmDSM - MAD
1 stop13h 05mKLM
Deal found 9/11$884
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMAD - DSM
2 stops17h 52mDelta
Mon 11/1011:28 amDSM - MAD
1 stop14h 47mDelta
Deal found 9/10$890

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.

Fly from

Madrid

Fly to

Des Moines

Route

Depart

Return

Price

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 9/27

1:45 pm-9:40 pm

1 stop14h 55m

Des Moines

Wed 10/1

1:40 pm-9:35 am

1 stop12h 55m

$841

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 11/21

1:45 pm-2:19 pm

2 stops31h 34m

Des Moines

Thu 11/27

11:26 am-8:05 am

2 stops13h 39m

$851

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 10/25

1:45 pm-10:28 pm

2 stops15h 43m

Des Moines

Sat 11/1

9:30 am-9:25 am

1 stop17h 55m

$851

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 11/6

6:00 am-9:32 pm

2 stops22h 32m

Des Moines

Mon 11/10

6:50 pm-8:00 am

2 stops30h 10m

$853

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 11/6

11:35 am-11:50 pm

1 stop19h 15m

Des Moines

Mon 11/10

2:19 pm-7:55 am

1 stop10h 36m

$858

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 11/21

1:35 pm-10:42 am

3 stops28h 07m

Des Moines

Thu 11/27

8:02 am-8:00 am

3 stops16h 58m

$877

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 11/21

6:00 am-5:12 pm

2 stops18h 12m

Des Moines

Thu 11/27

1:10 pm-9:15 am

1 stop13h 05m

$884

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 11/6

6:00 am-4:52 pm

2 stops17h 52m

Des Moines

Mon 11/10

11:28 am-9:15 am

1 stop14h 47m

$890

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 9/26

6:30 pm-9:48 pm

3 stops58h 18m

$568

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 9/26

10:35 am-6:09 pm

2 stops38h 34m

$720

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 11 results
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Best time to book a flight from Madrid to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Des Moines

How much does it cost to fly round-trip from Madrid to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Des Moines?

    Departing from Madrid to Des Moines will take you 14h 55m. Madrid and Des Moines are separated by a distance of 4457 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Madrid to Des Moines that include hotel bookings?

    Yes. In addition to deals on Madrid to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Des Moines.

  • Can I find deals for business class flights from Madrid to Des Moines?

    Yes. Cheapflights offers flight deals from Madrid to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Madrid to Des Moines (average of $336). Flying from Madrid to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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