HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$379+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
Aug 11 — Aug 181
Tue 8/11
Tue 8/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Madrid to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Madrid to Des Moines

Cheapest flights from Madrid to Des Moines
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 12, 2026.

This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:25 am
MAD
-
DSM
2 stops22h 10m
United Airlines
Sun 10/118:00 am
DSM
-
MAD
2 stops17h 05m
United Airlines
Deal found 7/8$976
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:00 am
MAD
-
DSM
2 stops21h 49m
Delta
Wed 7/295:52 pm
DSM
-
MAD
2 stops14h 43m
Delta
Deal found 7/9$1,140
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
MAD
-
DSM
2 stops21h 59m
Delta
Mon 8/175:30 pm
DSM
-
MAD
2 stops16h 15m
Delta
Deal found 7/11$1,165
This KLM deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
MAD
-
DSM
2 stops17h 50m
KLM
Mon 8/1711:28 am
DSM
-
MAD
1 stop17h 47m
KLM
Deal found 7/11$1,168
This Trip.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:50 am
MAD
-
DSM
1 stop19h 39m
Virgin Atlantic
Wed 7/296:37 pm
DSM
-
MAD
1 stop34h 38m
Virgin Atlantic
Deal found 7/9$1,175
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:50 am
MAD
-
DSM
2 stops43h 54m
United Airlines
Sat 6/58:00 am
DSM
-
MAD
2 stops41h 05m
United Airlines
Deal found 7/7$1,186
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:50 am
MAD
-
DSM
1 stop13h 07m
Air France
Wed 7/2911:30 am
DSM
-
MAD
2 stops16h 50m
Air France
Deal found 7/9$1,189
This Trip.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:50 am
MAD
-
DSM
1 stop19h 47m
Virgin Atlantic
Mon 8/176:35 pm
DSM
-
MAD
1 stop34h 40m
Virgin Atlantic
Deal found 7/11$1,199
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:35 pm
MAD
-
DSM
1 stop12h 34m
American Airlines
Sun 10/117:42 pm
DSM
-
MAD
1 stop30h 23m
American Airlines
Deal found 7/8$1,213
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:20 am
MAD
-
DSM
2 stops35h 06m
United Airlines
Fri 6/48:00 am
DSM
-
MAD
2 stops41h 50m
United Airlines
Deal found 7/7$1,217

Find flight deals from Madrid to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 12, 2026.

Round-trip from

$976
(United Airlines)

One-way from

$379
(Kiwi.com)

Popular in

November

Cheapest in

September
From Madrid Barajas to Des Moines
Search Deals
One-way flight from Madrid Barajas to Des Moines
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($365 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($156 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 12, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 10/7

5:55 am-9:23 pm

2 stops22h 28m

Des Moines

Sun 10/11

8:00 am-9:00 am

2 stops18h 00m

$976

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 8/10

6:00 am-8:59 pm

2 stops21h 59m

Des Moines

Mon 8/17

5:30 pm-4:45 pm

2 stops16h 15m

$1,165

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 8/10

6:00 am-4:50 pm

2 stops17h 50m

Des Moines

Mon 8/17

11:28 am-12:15 pm

1 stop17h 47m

$1,168

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 8/14

10:50 am-11:44 pm

2 stops43h 54m

Des Moines

Sat 6/5

8:00 am-8:05 am

2 stops41h 05m

$1,186
Quickest round-trip

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Sat 7/25

9:50 am-3:57 pm

1 stop13h 07m

Des Moines

Wed 7/29

11:30 am-11:20 am

2 stops16h 50m

$1,189

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Mon 8/10

9:50 am-10:37 pm

1 stop19h 47m

Des Moines

Mon 8/17

6:35 pm-12:15 pm

1 stop34h 40m

$1,199

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 10/7

3:25 pm-10:43 pm

1 stop14h 18m

Des Moines

Sun 10/11

7:42 pm-9:05 am

1 stop30h 23m

$1,213

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Fri 8/14

6:20 am-10:26 am

2 stops35h 06m

Des Moines

Fri 6/4

8:00 am-8:50 am

2 stops41h 50m

$1,217
Cheapest one-way

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Thu 9/17

5:50 am-2:14 pm

3 stops39h 24m

$406

MadridDes Moines

MAD - DSM

MADDSM

Madrid Barajas

Wed 12/2

9:10 pm-2:00 pm

2 stops47h 50m

$457

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/9

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Best time to book a flight from Madrid to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Des Moines?

    Departing from Madrid to Des Moines will take you 17h 50m. Madrid and Des Moines are separated by a distance of 4457 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Madrid to Des Moines that include hotel bookings?

    Yes. In addition to deals on Madrid to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Des Moines.

  • Can I find deals for business class flights from Madrid to Des Moines?

    Yes. Cheapflights offers flight deals from Madrid to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Des Moines by adding a car rental and/or hotel reservation to your travel itinerary.
Des Moines car rentals
Des Moines Airport car rentals
Waterloo Airport car rentals
Fort Dodge Airport car rentals
Cedar Rapids car rentals
Sioux City car rentals

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.