$572+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/23. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Madrid to Des Moines
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Cheapest flights from Madrid to Des MoinesExplore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
2 stops24h 30m
Thu 10/296:45 pm -
2 stops17h 05m
Deal found 9/7![Lufthansa logo]()
$975
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops18h 19m
Sun 9/275:35 pm -
2 stops15h 00m
Deal found 9/7![Delta logo]()
$985
This Flighttix deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:50 am -
1 stop19h 36m
Sun 9/275:45 am -
1 stop23h 30m
Deal found 9/6![Virgin Atlantic logo]()
$992
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
2 stops18h 23m
Sun 11/158:00 am -
2 stops18h 15m
Deal found 9/6![United Airlines logo]()
$1,003
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:45 pm -
2 stops28h 45m
Sun 9/276:00 am -
3 stops17h 50m
Deal found 9/6![Multiple Airlines logo]()
$1,033
This British Airways deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:40 pm -
1 stop13h 16m
Sun 11/159:25 am -
2 stops19h 50m
Deal found 9/5![British Airways logo]()
$1,086
Best flights from Madrid to Des MoinesDiscover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops18h 19m
Sun 9/275:35 pm -
2 stops15h 00m
Deal found 9/6![Delta logo]()
$985
This Flighttix deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:45 pm -
2 stops16h 41m
Sun 9/275:45 am -
1 stop23h 30m
Deal found 9/6![Virgin Atlantic logo]()
$988
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
2 stops18h 23m
Sun 11/158:00 am -
2 stops18h 15m
Deal found 9/8![United Airlines logo]()
$1,004
This British Airways deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:40 pm -
1 stop13h 16m
Sun 11/159:25 am -
2 stops19h 50m
Deal found 9/6![British Airways logo]()
$1,086
This Virgin Atlantic deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:50 am -
1 stop15h 19m
Thu 10/293:03 pm -
1 stop12h 42m
Deal found 9/7![Virgin Atlantic logo]()
$994
Last-minute flights from Madrid to Des MoinesDiscover last-minute flight deals from Madrid to Des Moines. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Des Moines. Data last updated September 9, 2026 and is based on user searches.
This Rumbo deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:30 am -
2 stops16h 56m
Sat 9/265:57 pm -
1 stop31h 23m
Deal found 9/6![Multiple Airlines logo]()
$1,247
This Rumbo deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:30 am -
2 stops16h 56m
Sat 9/2610:35 am -
2 stops40h 20m
Deal found 9/6![Aer Lingus logo]()
$1,406
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:00 am -
2 stops18h 19m
Sun 9/275:35 pm -
2 stops15h 00m
Deal found 9/7![Delta logo]()
$985
This Flighttix deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:50 am -
1 stop19h 36m
Sun 9/275:45 am -
1 stop23h 30m
Deal found 9/6![Virgin Atlantic logo]()
$992
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:45 pm -
2 stops28h 45m
Sun 9/276:00 am -
3 stops17h 50m
Deal found 9/6![Multiple Airlines logo]()
$1,033
This Cheapflightsfares deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:05 am -
2 stops24h 30m
Thu 10/296:45 pm -
2 stops17h 05m
Deal found 9/7![Lufthansa logo]()
$975
One-way flights from Madrid to Des MoinesSearch for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:10 pm -
2 stops47h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2111:00 pm -
3 stops52h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$688
This Virgin Atlantic deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2112:20 pm -
1 stop17h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Virgin Atlantic logo]()
$878
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/231:00 pm -
1 stop17h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$915
Find flight deals from Madrid to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Round-trip from | $975 (Cheapflightsfares) |
|---|---|
One-way from | $572 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 12/23
9:10 pm-2:00 pm
2 stops47h 50m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$572
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Mon 12/21
9:10 pm-3:02 pm
2 stops48h 52m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$764
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Mon 12/21
12:20 pm-10:38 pm
1 stop17h 18m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$878
Quickest round-trip
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 12/23
1:00 pm-11:08 pm
1 stop17h 08m
Des Moines
Wed 12/31
12:00 am-7:00 am
Nonstop0h 00m
$915
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 9/23
6:00 am-5:19 pm
2 stops18h 19m
Des Moines
Sun 9/27
5:35 pm-3:35 pm
2 stops15h 00m
$985
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 9/23
12:45 pm-10:26 pm
2 stops16h 41m
Des Moines
Sun 9/27
5:45 am-12:15 pm
1 stop23h 30m
$988
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Thu 10/22
9:50 am-6:09 pm
1 stop15h 19m
Des Moines
Thu 10/29
3:03 pm-9:45 am
1 stop12h 42m
$994
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 11/11
6:05 am-5:28 pm
2 stops18h 23m
Des Moines
Sun 11/15
8:00 am-9:15 am
2 stops18h 15m
$1,004
MadridDes Moines
MAD Madrid Barajas - DSM Des Moines
MADDSM
Madrid Barajas
Wed 11/11
12:40 pm-6:56 pm
1 stop13h 16m
Des Moines
Sun 11/15
9:25 am-12:15 pm
2 stops19h 50m
$1,086
Sorted by cheapest first
Best time to book a flight from Madrid to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
MAD-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Clive
Ames
Johnston
Boone
Norwalk
West Des Moines
Ankeny
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