$524+ Cheap flights from Madrid, Spain (MAD) to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — DSM
May 11 — May 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Madrid to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Madrid to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Madrid to Des MoinesExplore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
Explore the most affordable flight options available from Madrid to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
This KLM deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 am
MAD
- DSM
2 stops16h 44m
Multiple Airlines
Wed 10/285:25 pm
DSM
- MAD
2 stops15h 55m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$964
This KLM deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
MAD
- DSM
2 stops17h 49m
KLM
Wed 10/286:30 pm
DSM
- MAD
1 stop33h 25m
KLM
Deal found 4/8![KLM logo]()
$967
This Air France deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MAD
- DSM
2 stops18h 02m
Multiple Airlines
Wed 4/295:45 pm
DSM
- MAD
2 stops15h 40m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$985
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:55 am
MAD
- DSM
2 stops23h 31m
United Airlines
Wed 10/288:00 am
DSM
- MAD
3 stops17h 00m
United Airlines
Deal found 4/8![United Airlines logo]()
$986
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:55 am
MAD
- DSM
2 stops24h 21m
United Airlines
Sun 5/318:15 pm
DSM
- MAD
2 stops29h 35m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,000
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:50 am
MAD
- DSM
2 stops17h 42m
United Airlines
Wed 4/298:04 am
DSM
- MAD
2 stops17h 01m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,007
This Trip.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:50 am
MAD
- DSM
1 stop17h 32m
Virgin Atlantic
Sat 5/304:00 pm
DSM
- MAD
1 stop13h 15m
Virgin Atlantic
Deal found 4/8![Virgin Atlantic logo]()
$1,021
Best flights from Madrid to Des MoinesDiscover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
Discover carefully curated flight deals from Madrid to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
This KLM deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
MAD
- DSM
2 stops17h 49m
KLM
Wed 10/286:30 pm
DSM
- MAD
1 stop33h 25m
KLM
Deal found 4/8![KLM logo]()
$967
This KLM deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 am
MAD
- DSM
2 stops16h 44m
Multiple Airlines
Wed 10/285:25 pm
DSM
- MAD
2 stops15h 55m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$975
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:55 am
MAD
- DSM
2 stops23h 31m
United Airlines
Wed 10/288:00 am
DSM
- MAD
3 stops17h 00m
United Airlines
Deal found 4/8![United Airlines logo]()
$986
This Iberia deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:35 pm
MAD
- DSM
1 stop17h 33m
Iberia
Wed 6/107:06 pm
DSM
- MAD
1 stop30h 14m
Iberia
Deal found 4/7![Iberia logo]()
$1,029
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:55 am
MAD
- DSM
2 stops24h 21m
United Airlines
Sun 5/318:15 pm
DSM
- MAD
2 stops29h 35m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,000
This KLM deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:45 pm
MAD
- DSM
1 stop16h 49m
KLM
Wed 4/2910:34 am
DSM
- MAD
2 stops15h 56m
KLM
Deal found 4/9![KLM logo]()
$1,007
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:50 am
MAD
- DSM
2 stops17h 42m
United Airlines
Wed 4/298:04 am
DSM
- MAD
2 stops17h 01m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,007
Last-minute flights from Madrid to Des MoinesDiscover last-minute flight deals from Madrid to Des Moines. Data last updated April 11, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Des Moines. Data last updated April 11, 2026 and is based on user searches.
This KLM deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1210:25 am
MAD
- DSM
2 stops17h 20m
Multiple Airlines
Wed 4/155:45 pm
DSM
- MAD
2 stops16h 00m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$1,593
This KLM deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
MAD
- DSM
2 stops16h 42m
KLM
Wed 4/1511:51 am
DSM
- MAD
1 stop17h 24m
KLM
Deal found 4/9![KLM logo]()
$1,596
This Air France deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MAD
- DSM
2 stops18h 02m
Multiple Airlines
Wed 4/295:45 pm
DSM
- MAD
2 stops15h 40m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$985
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:50 am
MAD
- DSM
2 stops17h 42m
United Airlines
Wed 4/298:04 am
DSM
- MAD
2 stops17h 01m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,007
This Iberia deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:35 pm
MAD
- DSM
1 stop17h 14m
Iberia
Wed 4/298:03 pm
DSM
- MAD
1 stop29h 17m
Iberia
Deal found 4/9![Iberia logo]()
$1,059
This British Airways deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:40 am
MAD
- DSM
2 stops18h 53m
British Airways
Wed 4/298:03 pm
DSM
- MAD
1 stop10h 27m
British Airways
Deal found 4/9![British Airways logo]()
$1,174
This Trip.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:50 am
MAD
- DSM
1 stop17h 32m
Virgin Atlantic
Sat 5/304:00 pm
DSM
- MAD
1 stop13h 15m
Virgin Atlantic
Deal found 4/8![Virgin Atlantic logo]()
$1,021
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:00 am
MAD
- DSM
2 stops17h 48m
Delta
Sat 5/305:27 am
DSM
- MAD
2 stops21h 28m
Delta
Deal found 4/8![Delta logo]()
$1,045
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:55 am
MAD
- DSM
2 stops24h 21m
United Airlines
Sun 5/318:15 pm
DSM
- MAD
2 stops29h 35m
United Airlines
Deal found 4/9![United Airlines logo]()
$1,000
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:35 am
MAD
- DSM
2 stops38h 25m
Multiple Airlines
Sun 5/317:30 am
DSM
- MAD
1 stop16h 20m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$1,129
One-way flights from Madrid to Des MoinesSearch for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
Search for one-way flight options from Madrid to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:05 am
MAD
- DSM
3 stops56h 02m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:25 pm
MAD
- DSM
2 stops46h 35m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$572
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:25 pm
MAD
- DSM
3 stops45h 44m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$590
This Kiwi.com deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:55 pm
MAD
- DSM
3 stops29h 57m
Multiple Airlines
Deal found 4/11![Multiple Airlines logo]()
$591
This FlightHub deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:55 am
MAD
- DSM
2 stops16h 57m
WestJet
Deal found 4/11![WestJet logo]()
$595
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:40 pm
MAD
- DSM
2 stops31h 20m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:55 am
MAD
- DSM
3 stops54h 14m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$618
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:25 pm
MAD
- DSM
3 stops46h 25m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$627
Find flight deals from Madrid to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 11, 2026.
Round-trip from | $964 (KLM) |
|---|---|
One-way from | $571 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $1,071 |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Madrid to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Wed 8/26
6:00 am-4:49 pm
2 stops17h 49m
Des Moines
Wed 10/28
6:30 pm-9:55 am
1 stop33h 25m
$967
Quickest round-trip
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Wed 8/26
7:05 am-4:49 pm
2 stops16h 44m
Des Moines
Wed 10/28
5:25 pm-3:20 pm
2 stops15h 55m
$975
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Wed 8/26
5:55 am-10:26 pm
2 stops23h 31m
Des Moines
Wed 10/28
8:00 am-7:00 am
3 stops17h 00m
$986
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Sun 5/24
5:55 am-11:16 pm
2 stops24h 21m
Des Moines
Sun 5/31
8:15 pm-8:50 am
2 stops29h 35m
$1,000
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Sat 4/25
12:45 pm-10:34 pm
1 stop16h 49m
Des Moines
Wed 4/29
10:34 am-9:30 am
2 stops15h 56m
$1,007
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Sat 4/25
10:50 am-9:32 pm
2 stops17h 42m
Des Moines
Wed 4/29
8:04 am-8:05 am
2 stops17h 01m
$1,007
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Wed 6/3
1:35 pm-12:08 am
1 stop17h 33m
Des Moines
Wed 6/10
7:06 pm-8:20 am
1 stop30h 14m
$1,029
Cheapest one-way
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Mon 6/29
9:55 pm-8:52 pm
3 stops29h 57m
$591
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Wed 7/29
6:00 pm-1:50 pm
3 stops50h 50m
$643
MadridDes Moines
MAD - DSM
MADDSM
Madrid Barajas
Sat 6/27
6:00 am-2:18 pm
3 stops39h 18m
$645
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Madrid to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Madrid with our price prediction graph.
MAD-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Ankeny
Boone
West Des Moines
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Complete your trip
Des Moines flight routes
Flights by cabin class
Other flight options
Other flights from Madrid
Popular flights