How long is the flight from Louisville to Des Moines?

For as low as $258, American Airlines can have you in Des Moines from Louisville in 4h 54m. Airlines will cover a distance of 480 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Louisville to Des Moines round-trip?

Flying on Delta is currently your cheapest option to Des Moines, with prices starting at $105. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $196 and $223, respectively.

What are the cheapest airlines to fly from Louisville to Des Moines one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $164. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Louisville to Des Moines for a low price.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular airlines that fly from Louisville to Des Moines?

Consider Delta, American Airlines or United Airlines when booking your flight. These represent the most popular airlines when flying from Louisville to Des Moines.

Most accurate provider : When it comes to deals on Louisville-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Louisville to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.

Can I find deals for business class flights from Louisville to Des Moines?

Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$164+ Flights from Louisville to Des Moines

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Find flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

Tue 12/308:00 amSDF - DSM

1 stop6h 21mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$258

Mon 12/295:49 pmSDF - DSM

1 stop6h 57mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$296

Wed 11/199:00 amSDF - DSM

1 stop4h 14mUnited Airlines

Sun 11/2311:26 amDSM - SDF

1 stop4h 50mUnited Airlines

Deal found 11/4

$407

Wed 11/196:44 amSDF - DSM

1 stop6h 21mAmerican Airlines

Sun 11/231:06 pmDSM - SDF

2 stops7h 40mAmerican Airlines

Deal found 11/4

$412

Fri 11/216:25 amSDF - DSM

2 stops7h 57mAmerican Airlines

Tue 11/255:41 amDSM - SDF

2 stops8h 16mAmerican Airlines

Deal found 11/6

$417

Best flights from Louisville to Des Moines
Discover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2025.

Tue 12/308:00 amSDF - DSM

1 stop6h 21mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$258

Thu 2/196:23 amSDF - DSM

1 stop4h 54mDelta

Mon 2/235:15 pmDSM - SDF

1 stop5h 35mDelta

Deal found 11/3

$258

Mon 12/295:49 pmSDF - DSM

1 stop6h 57mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$296

Last-minute flights from Louisville to Des Moines
Discover last-minute flight deals from Louisville to Des Moines. Data last updated November 6, 2025 and is based on user searches.

Wed 11/199:00 amSDF - DSM

1 stop4h 14mUnited Airlines

Sun 11/2311:26 amDSM - SDF

1 stop4h 50mUnited Airlines

Deal found 11/4

$407

Wed 11/196:44 amSDF - DSM

1 stop6h 21mAmerican Airlines

Sun 11/231:06 pmDSM - SDF

2 stops7h 40mAmerican Airlines

Deal found 11/4

$412

Fri 11/216:25 amSDF - DSM

2 stops7h 57mAmerican Airlines

Tue 11/255:41 amDSM - SDF

2 stops8h 16mAmerican Airlines

Deal found 11/6

$417

Mon 12/295:49 pmSDF - DSM

1 stop6h 57mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$296

Tue 12/308:00 amSDF - DSM

1 stop6h 21mAmerican Airlines

Mon 1/53:27 pmDSM - SDF

1 stop7h 03mAmerican Airlines

Deal found 11/4

$258

One-way flights from Louisville to Des Moines
Search for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated November 6, 2025.

Sun 12/287:24 pmSDF - DSM

1 stop6h 13mAmerican Airlines

Deal found 11/4

$164

Mon 12/12:22 pmSDF - DSM

1 stop7h 25mDelta

Deal found 11/4

$174

Sun 12/285:05 amSDF - DSM

2 stops6h 55mSouthwest

Deal found 11/4

$229

Mon 12/11:30 pmSDF - DSM

2 stops11h 35mSouthwest

Deal found 11/4

$244

Sun 12/282:55 pmSDF - DSM

3 stops57h 06mMultiple Airlines

Deal found 11/4

$340

Mon 12/19:09 amSDF - DSM

3 stops52h 26mAllegiant Air

Deal found 11/4

$375

Cheap flight deals from Louisville to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$258 (American Airlines)
One-way from	$164 (American Airlines)

Provider with most accurate pricing for Louisville Intl-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Louisville Intl-Des Moines flights.

Search Deals

From Louisville Intl to Des Moines

Search Deals

One-way flight from Louisville Intl to Des Moines

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 12/30

8:00 am-1:21 pm

1 stop6h 21m

Des Moines

Mon 1/5

3:27 pm-11:30 pm

1 stop7h 03m

$258

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 2/19

6:23 am-10:17 am

1 stop4h 54m

Des Moines

Mon 2/23

5:15 pm-11:50 pm

1 stop5h 35m

$258

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Mon 12/29

5:49 pm-11:46 pm

1 stop6h 57m

Des Moines

Mon 1/5

3:27 pm-11:30 pm

1 stop7h 03m

$296

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sun 12/28

7:24 pm-12:37 am

1 stop6h 13m

$164

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Mon 12/1

2:22 pm-8:47 pm

1 stop7h 25m

$174

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sun 12/28

5:05 am-11:00 am

2 stops6h 55m

$229

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Mon 12/1

1:30 pm-12:05 am

2 stops11h 35m

$244

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sun 12/28

2:55 pm-11:01 pm

3 stops57h 06m

$340

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Mon 12/1

9:09 am-12:35 pm

3 stops52h 26m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Compare providers for flights from Louisville to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in November.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Des Moines

What is the cheapest month to book a flight from Louisville to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $157). Flying from Louisville to Des Moines in December is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to DSM?

It’s optimal to fly from Louisville to Des Moines in the afternoon. By choosing this option you can save up to 16% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Des Moines

Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,004 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,004 reviews

Delta

7.9

Good

8,004 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,003 reviews

Delta

7.9

Good

8,004 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,042 reviews

Delta

7.9

Good

8,004 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Louisville to Des Moines?
For as low as $258, American Airlines can have you in Des Moines from Louisville in 4h 54m. Airlines will cover a distance of 480 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Louisville to Des Moines round-trip?
Flying on Delta is currently your cheapest option to Des Moines, with prices starting at $105. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $196 and $223, respectively.
What are the cheapest airlines to fly from Louisville to Des Moines one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $164. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Louisville to Des Moines for a low price.
Can I find deals for flights from Louisville to Des Moines that include hotel bookings?
Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Louisville to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.
Can I find deals for business class flights from Louisville to Des Moines?
Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Louisville to Des Moines?
Currently, March is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $157). Flying from Louisville to Des Moines in December is currently the most expensive (average of $351). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Johnston

Altoona

Boone

Ames

West Des Moines

Ankeny

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Other flights to Des Moines

Top 3 airlines flying from Louisville to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$105	Average$472	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$196	Average$305	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$223	Average$456	FlexibilityNo cancel fee	On-time69%

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$164+ Cheap flights from Louisville to Des Moines (SDF - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Louisville to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des MoinesExplore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

Cheap flight deals from Louisville to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Compare providers for flights from Louisville to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in November.

Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Des Moines

What is the cheapest month to book a flight from Louisville to Des Moines?

What is the cheapest time of day to fly from SDF to DSM?

Reviews of airlines servicing Des Moines

Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Louisville to Des Moines?

What are the cheapest airlines flying from Louisville to Des Moines round-trip?

What are the cheapest airlines to fly from Louisville to Des Moines one-way?

Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

How can I find direct flights from Louisville to Des Moines?

Can I find deals for business class flights from Louisville to Des Moines?

What is the cheapest month to book a flight from Louisville to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Louisville to Des Moines

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Top 3 airlines flying from Louisville to Des Moines

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Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.