What are the cheapest airlines flying from Louisville to Des Moines round-trip?

Flying on American Airlines is currently your cheapest option to Des Moines, with prices starting at $251. Additional round-trip tickets that might be worth considering are offered by Southwest and Delta, with the lowest prices starting at $325 and $387, respectively. American Airlines is 36% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Louisville to Des Moines?

Travelers seeking maximum savings on their Louisville to Des Moines flight should consider departing on Saturday mornings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Louisville to Des Moines?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Louisville to Des Moines.

What is the cheapest day to fly round-trip from Louisville to Des Moines?

Flying to your destination on a Tuesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Des Moines. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Louisville to Des Moines?

The best pricing can be found in the month of December. Prices to Des Moines from Louisville average $393. You can even find prices in December for less than $393, as users have found deals to Des Moines from as low as $228. The month of June appears to be one of the more expensive times to travel to Des Moines from Louisville. Flying in the targeted month can save you up to 42%.

Most accurate provider : When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Louisville to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.

Can I find deals for business class flights from Louisville to Des Moines?

Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$147+ Flights from Louisville to Des Moines - Compare & Save Big

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1. Tell us where you want to go

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Cheap flight deals from Louisville to Des Moines

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$251 (American Airlines)
One-way from	$147 (Delta)
Popular in	June
Cheapest in	December
Average price	$475

Provider with most accurate pricing for Louisville Intl-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Louisville Intl-Des Moines flights.

Search Deals

From Louisville Intl to Des Moines

Search Deals

One-way flight from Louisville Intl to Des Moines

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($19 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Fri 5/307:05 amSDF - DSM

1 stop6h 16mAmerican Airlines

Mon 6/25:27 pmDSM - SDF

1 stop5h 58mAmerican Airlines

Deal found 4/27

$251

Fri 5/304:50 pmSDF - DSM

1 stop6h 20mSouthwest

Mon 6/26:00 amDSM - SDF

2 stops9h 15mSouthwest

Deal found 4/27

$325

Mon 5/125:55 pmSDF - DSM

1 stop5h 35mDelta

Thu 5/156:35 pmDSM - SDF

1 stop4h 30mDelta

Deal found 4/28

$387

Thu 7/248:40 amSDF - DSM

1 stop7h 01mUnited Airlines

Sun 7/276:50 pmDSM - SDF

2 stops14h 37mUnited Airlines

Deal found 4/28

$531

Best flights from Louisville to Des Moines
Discover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 30, 2025.

Fri 5/307:05 amSDF - DSM

1 stop6h 16mAmerican Airlines

Mon 6/25:27 pmDSM - SDF

1 stop5h 58mAmerican Airlines

Deal found 4/27

$251

Fri 5/304:50 pmSDF - DSM

1 stop6h 20mSouthwest

Mon 6/26:00 amDSM - SDF

2 stops9h 15mSouthwest

Deal found 4/27

$325

Mon 5/125:55 pmSDF - DSM

1 stop5h 35mDelta

Thu 5/156:35 pmDSM - SDF

1 stop4h 30mDelta

Deal found 4/28

$387

Thu 7/248:40 amSDF - DSM

1 stop7h 01mUnited Airlines

Sun 7/276:50 pmDSM - SDF

2 stops14h 37mUnited Airlines

Deal found 4/28

$531

Last-minute flights from Louisville to Des Moines
Discover last-minute flight deals from Louisville to Des Moines. Data last updated April 30, 2025 and is based on user searches.

Fri 5/26:07 pmSDF - DSM

1 stop4h 45mUnited Airlines

Sun 5/411:26 amDSM - SDF

1 stop4h 34mUnited Airlines

Deal found 4/29

$888

Mon 5/125:55 pmSDF - DSM

1 stop5h 35mDelta

Thu 5/156:35 pmDSM - SDF

1 stop4h 30mDelta

Deal found 4/28

$387

Fri 5/307:05 amSDF - DSM

1 stop6h 16mAmerican Airlines

Mon 6/25:27 pmDSM - SDF

1 stop5h 58mAmerican Airlines

Deal found 4/27

$251

Fri 5/304:50 pmSDF - DSM

1 stop6h 20mSouthwest

Mon 6/26:00 amDSM - SDF

2 stops9h 15mSouthwest

Deal found 4/27

$325

One-way flights from Louisville to Des Moines
Search for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated April 30, 2025.

Thu 6/193:04 pmSDF - DSM

1 stop6h 33mDelta

Deal found 4/29

$147

Thu 6/57:00 amSDF - DSM

1 stop4h 20mUnited Airlines

Deal found 4/28

$158

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 5/30

7:05 am-12:21 pm

1 stop6h 16m

Des Moines

Mon 6/2

5:27 pm-12:25 am

1 stop5h 58m

$251

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 5/30

4:50 pm-10:10 pm

1 stop6h 20m

Des Moines

Mon 6/2

6:00 am-4:15 pm

2 stops9h 15m

$325

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Mon 5/12

5:55 pm-10:30 pm

1 stop5h 35m

Des Moines

Thu 5/15

6:35 pm-12:05 am

1 stop4h 30m

$387

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 7/24

8:40 am-2:41 pm

1 stop7h 01m

Des Moines

Sun 7/27

6:50 pm-10:27 am

2 stops14h 37m

$531

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 6/19

6:05 am-10:19 am

1 stop5h 14m

$147

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 6/5

7:00 am-10:20 am

1 stop4h 20m

$158

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Compare providers for flights from Louisville to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in April.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
Expedia	Price Accuracy1 star	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Des Moines

What is the cheapest month to book a flight from Louisville to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $336). Flying from Louisville to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to DSM?

It’s optimal to fly from Louisville to Des Moines in the afternoon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.

Rainfall in Des Moines by month

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

Temperature in Des Moines by month

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Reviews of airlines servicing Des Moines

Southwest

8.0

Very good

4,295 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Southwest

8.0

Very good

4,295 reviews

Southwest

8.0

Very good

4,295 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Delta

8.0

Very good

7,936 reviews

Southwest

8.0

Very good

4,295 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

United Airlines

7.4

Good

8,696 reviews

Southwest

8.0

Very good

4,295 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,295 reviews

Reviews

1 / 20

10.0

Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

What are the cheapest airlines flying from Louisville to Des Moines round-trip?
Flying on American Airlines is currently your cheapest option to Des Moines, with prices starting at $251. Additional round-trip tickets that might be worth considering are offered by Southwest and Delta, with the lowest prices starting at $325 and $387, respectively. American Airlines is 36% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Louisville to Des Moines that include hotel bookings?
Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Louisville to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.
Can I find deals for business class flights from Louisville to Des Moines?
Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Louisville to Des Moines?
Currently, August is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $336). Flying from Louisville to Des Moines in June is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Ames

Altoona

Johnston

Boone

West Des Moines

Ankeny

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Other flights to Des Moines

Top 3 airlines flying from Louisville to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$228	Average$472	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$246	Average$426	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$246	Average$466	FlexibilityNo cancel fee	On-time69%

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$147+ Cheap flights from Louisville to Des Moines (SDF - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Louisville to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Louisville to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des MoinesExplore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Compare providers for flights from Louisville to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in April.

Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Des Moines

What is the cheapest month to book a flight from Louisville to Des Moines?

What is the cheapest time of day to fly from SDF to DSM?

Find hourly flight availability from Louisville to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Rainfall in Des Moines by month

Plan your trip to Des Moines by taking into account the average rainfall totals by month.

Temperature in Des Moines by month

Plan your trip to Des Moines by taking into account the average temperature totals by month.

Reviews of airlines servicing Des Moines

Related info for your journey

Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Louisville to Des Moines round-trip?

Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

How can I find direct flights from Louisville to Des Moines?

Can I find deals for business class flights from Louisville to Des Moines?

What is the cheapest month to book a flight from Louisville to Des Moines?

Traveling to a place near Louisville?

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Alternative routes for Louisville to Des Moines

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Top 3 airlines flying from Louisville to Des Moines

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Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.