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Des Moines

$123+ Cheap flights from Louisville to Des Moines (SDF - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Louisville to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2025.

Round-trip from

$227
(American Airlines)

One-way from

$123
(American Airlines)

Popular in

October

Cheapest in

June

Average price

$376
From Louisville Intl to Des Moines
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One-way flight from Louisville Intl to Des Moines
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Highest demand for flights based on searches. 1% potential increase in price ($4 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Louisville to Des Moines

Cheapest flights from Louisville to Des Moines
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/303:09 pmSDF - DSM
1 stop7h 36mAmerican Airlines
Sun 8/313:49 pmDSM - SDF
1 stop6h 02mAmerican Airlines
Deal found 8/17$227
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:18 pmSDF - DSM
1 stop6h 48mAmerican Airlines
Mon 9/225:38 pmDSM - SDF
1 stop4h 37mAmerican Airlines
Deal found 8/18$276
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/316:25 pmSDF - DSM
1 stop5h 32mAmerican Airlines
Mon 9/11:09 pmDSM - SDF
1 stop3h 29mAmerican Airlines
Deal found 8/17$297
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amSDF - DSM
2 stops12h 08mMultiple Airlines
Sun 11/1610:50 amDSM - SDF
1 stop22h 09mMultiple Airlines
Deal found 8/17$302
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:29 amSDF - DSM
1 stop6h 24mAmerican Airlines
Sun 11/161:24 pmDSM - SDF
1 stop7h 05mAmerican Airlines
Deal found 8/17$307
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:15 pmSDF - DSM
2 stops10h 35mSouthwest
Mon 9/221:55 pmDSM - SDF
1 stop8h 45mSouthwest
Deal found 8/18$353
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/26:00 pmSDF - DSM
1 stop5h 43mDelta
Sat 9/611:23 amDSM - SDF
1 stop6h 17mDelta
Deal found 8/18$367
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1412:55 pmSDF - DSM
2 stops11h 40mSouthwest
Sun 11/165:45 amDSM - SDF
2 stops9h 10mSouthwest
Deal found 8/17$369
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/25:01 pmSDF - DSM
1 stop6h 57mAmerican Airlines
Sat 9/67:08 amDSM - SDF
2 stops8h 22mAmerican Airlines
Deal found 8/18$372

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.

Fly from

Louisville

Fly to

Des Moines

Route

Depart

Return

Price

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sat 8/30

3:09 pm-9:45 pm

1 stop7h 36m

Des Moines

Sun 8/31

3:49 pm-10:51 pm

1 stop6h 02m

$227

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 9/19

5:18 pm-11:06 pm

1 stop6h 48m

Des Moines

Mon 9/22

5:38 pm-11:15 pm

1 stop4h 37m

$276

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Sun 8/31

6:25 pm-10:57 pm

1 stop5h 32m

Des Moines

Mon 9/1

1:09 pm-5:38 pm

1 stop3h 29m

$297

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 11/14

6:00 am-5:08 pm

2 stops12h 08m

Des Moines

Sun 11/16

10:50 am-9:59 am

1 stop22h 09m

$302

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 11/14

7:29 am-12:53 pm

1 stop6h 24m

Des Moines

Sun 11/16

1:24 pm-9:29 pm

1 stop7h 05m

$307

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 9/19

1:15 pm-10:50 pm

2 stops10h 35m

Des Moines

Mon 9/22

1:55 pm-11:40 pm

1 stop8h 45m

$353

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 9/2

6:00 pm-10:43 pm

1 stop5h 43m

Des Moines

Sat 9/6

11:23 am-6:40 pm

1 stop6h 17m

$367

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Fri 11/14

12:55 pm-11:35 pm

2 stops11h 40m

Des Moines

Sun 11/16

5:45 am-3:55 pm

2 stops9h 10m

$369

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Tue 9/2

5:01 pm-10:58 pm

1 stop6h 57m

Des Moines

Sat 9/6

7:08 am-4:30 pm

2 stops8h 22m

$372

LouisvilleDes Moines

SDF - DSM

SDFDSM

Louisville Intl

Thu 10/30

2:21 pm-8:11 pm

1 stop6h 50m

$123

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/18

Showing 1-10 of 17 results
1
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Best time to book a flight from Louisville to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Louisville to Des Moines

What is the cheapest month to book a flight from Louisville to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $336). Flying from Louisville to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDF to DSM?

Find hourly flight availability from Louisville to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

It’s optimal to fly from Louisville to Des Moines in the afternoon. By choosing this option you can save up to 17% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 18, 2025.
Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Des Moines?

    For as low as $227, American Airlines can have you in Des Moines from Louisville in 7h 36m. Airlines will cover a distance of 480 mi.

  • What are the cheapest airlines flying from Louisville to Des Moines round-trip?

    Flying on Delta is currently your cheapest option to Des Moines, with prices starting at $105. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $196 and $246, respectively. Delta is 68% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Louisville to Des Moines one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $123. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Louisville to Des Moines for a low price.

  • Can I find deals for flights from Louisville to Des Moines that include hotel bookings?

    Yes. In addition to deals on Louisville to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Des Moines.

  • Can I find deals for business class flights from Louisville to Des Moines?

    Yes. Cheapflights offers flight deals from Louisville to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Louisville to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Louisville to Des Moines (average of $336). Flying from Louisville to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top 3 airlines flying from Louisville to Des Moines

Discover the top 3 airlines that operate flights from Louisville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$105Average$472FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$366FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$246Average$446FlexibilityNo cancel feeOn-time69%

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