$146+ Cheap flights from Louisville to Des Moines (SDF - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — DSM
Apr 30 — May 71
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Des Moines
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Best
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Cheapest flights from Louisville to Des MoinesExplore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
Explore the most affordable flight options available from Louisville to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2026.
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:15 pm
SDF
- DSM
1 stop3h 55m
Southwest
Tue 5/265:30 am
DSM
- SDF
1 stop3h 20m
Southwest
Deal found 3/26![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Sat 5/165:35 am
DSM
- SDF
1 stop3h 30m
Southwest
Deal found 3/26![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:55 am
SDF
- DSM
1 stop3h 30m
Southwest
Wed 4/223:15 pm
DSM
- SDF
1 stop4h 20m
Southwest
Deal found 3/30![Southwest logo]()
$291
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Tue 4/216:55 am
DSM
- SDF
1 stop7h 55m
Southwest
Deal found 3/30![Southwest logo]()
$301
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Wed 4/225:30 am
DSM
- SDF
2 stops8h 15m
Southwest
Deal found 3/30![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:15 pm
SDF
- DSM
1 stop3h 55m
Southwest
Fri 5/295:25 am
DSM
- SDF
1 stop3h 30m
Southwest
Deal found 3/27![Southwest logo]()
$319
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 am
SDF
- DSM
1 stop5h 11m
Delta
Sun 6/76:39 pm
DSM
- SDF
1 stop4h 53m
Delta
Deal found 3/26![Delta logo]()
$332
Best flights from Louisville to Des MoinesDiscover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
Discover carefully curated flight deals from Louisville to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 31, 2026.
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:40 pm
SDF
- DSM
2 stops6h 30m
Southwest
Tue 5/265:30 am
DSM
- SDF
2 stops8h 15m
Southwest
Deal found 3/26![Southwest logo]()
$237
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:45 am
SDF
- DSM
1 stop4h 52m
Delta
Tue 5/265:28 pm
DSM
- SDF
1 stop5h 24m
Delta
Deal found 3/27![Delta logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:06 pm
SDF
- DSM
2 stops29h 36m
Multiple Airlines
Sun 5/32:36 pm
DSM
- SDF
1 stop27h 22m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:55 am
SDF
- DSM
1 stop3h 30m
Southwest
Wed 4/223:15 pm
DSM
- SDF
1 stop4h 20m
Southwest
Deal found 3/30![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:05 am
SDF
- DSM
1 stop5h 11m
Delta
Sun 6/76:39 pm
DSM
- SDF
1 stop4h 53m
Delta
Deal found 3/26![Delta logo]()
$332
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Tue 4/215:30 am
DSM
- SDF
2 stops8h 15m
Southwest
Deal found 3/30![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:25 pm
SDF
- DSM
2 stops6h 40m
Southwest
Wed 4/225:30 am
DSM
- SDF
2 stops8h 15m
Southwest
Deal found 3/30![Southwest logo]()
$311
This Southwest deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:15 pm
SDF
- DSM
1 stop3h 55m
Southwest
Fri 5/295:25 am
DSM
- SDF
1 stop3h 30m
Southwest
Deal found 3/27![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:40 pm
SDF
- DSM
2 stops6h 30m
Southwest
Sat 5/235:35 am
DSM
- SDF
2 stops17h 00m
Southwest
Deal found 3/29![Southwest logo]()
$368
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:25 pm
SDF
- DSM
2 stops6h 40m
Southwest
Sat 5/165:35 am
DSM
- SDF
2 stops17h 00m
Southwest
Deal found 3/26![Southwest logo]()
$369
Last-minute flights from Louisville to Des MoinesDiscover last-minute flight deals from Louisville to Des Moines. Data last updated March 31, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Des Moines. Data last updated March 31, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Tue 4/143:15 pm
DSM
- SDF
1 stop4h 20m
Southwest
Deal found 3/26![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Tue 4/216:55 am
DSM
- SDF
1 stop7h 55m
Southwest
Deal found 3/30![Southwest logo]()
$301
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:10 pm
SDF
- DSM
1 stop3h 55m
Southwest
Wed 4/225:30 am
DSM
- SDF
2 stops8h 15m
Southwest
Deal found 3/30![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:55 am
SDF
- DSM
1 stop3h 30m
Southwest
Wed 4/223:15 pm
DSM
- SDF
1 stop4h 20m
Southwest
Deal found 3/30![Southwest logo]()
$291
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:14 pm
SDF
- DSM
1 stop17h 59m
Multiple Airlines
Sun 5/32:36 pm
DSM
- SDF
1 stop17h 52m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$336
One-way flights from Louisville to Des MoinesSearch for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
Search for one-way flight options from Louisville to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 31, 2026.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:00 am
SDF
- DSM
1 stop5h 26m
American Airlines
Deal found 3/30![American Airlines logo]()
$146
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:40 pm
SDF
- DSM
2 stops6h 30m
Southwest
Deal found 3/30![Southwest logo]()
$151
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:00 pm
SDF
- DSM
1 stop5h 53m
Delta
Deal found 3/30![Delta logo]()
$174
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:25 pm
SDF
- DSM
2 stops6h 40m
Southwest
Deal found 3/30![Southwest logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:38 am
SDF
- DSM
1 stop22h 55m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$191
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:00 pm
SDF
- DSM
1 stop5h 45m
Delta
Deal found 3/28![Delta logo]()
$230
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/153:45 pm
SDF
- DSM
2 stops7h 25m
Southwest
Deal found 3/28![Southwest logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:48 pm
SDF
- DSM
3 stops42h 58m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/812:09 pm
SDF
- DSM
2 stops34h 57m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:33 pm
SDF
- DSM
2 stops30h 48m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$276
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:05 am
SDF
- DSM
1 stop4h 43m
Delta
Deal found 3/26![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:00 am
SDF
- DSM
2 stops9h 05m
American Airlines
Deal found 3/26![American Airlines logo]()
$284
Find flight deals from Louisville to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Southwest) |
One-way from | $146 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Louisville to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Tue 5/19
4:40 pm-10:10 pm
2 stops6h 30m
Des Moines
Tue 5/26
5:30 am-2:45 pm
2 stops8h 15m
$237
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Tue 4/21
8:55 am-11:25 am
1 stop3h 30m
Des Moines
Wed 4/22
3:15 pm-8:35 pm
1 stop4h 20m
$291
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Tue 5/19
9:45 am-1:37 pm
1 stop4h 52m
Des Moines
Tue 5/26
5:28 pm-11:52 pm
1 stop5h 24m
$301
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Mon 4/20
8:10 pm-11:05 pm
1 stop3h 55m
Des Moines
Tue 4/21
5:30 am-2:45 pm
2 stops8h 15m
$306
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Mon 4/20
5:25 pm-11:05 pm
2 stops6h 40m
Des Moines
Wed 4/22
5:30 am-2:45 pm
2 stops8h 15m
$311
Quickest round-trip
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Wed 5/20
7:15 pm-10:10 pm
1 stop3h 55m
Des Moines
Fri 5/29
5:25 am-9:55 am
1 stop3h 30m
$319
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Fri 5/29
6:05 am-10:16 am
1 stop5h 11m
Des Moines
Sun 6/7
6:39 pm-12:32 am
1 stop4h 53m
$332
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Sun 4/26
6:06 pm-10:42 pm
2 stops29h 36m
Des Moines
Sun 5/3
2:36 pm-6:58 pm
1 stop27h 22m
$350
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Wed 5/20
4:40 pm-10:10 pm
2 stops6h 30m
Des Moines
Sat 5/23
5:35 am-11:35 pm
2 stops17h 00m
$368
LouisvilleDes Moines
SDF - DSM
SDFDSM
Louisville Intl
Thu 5/14
5:25 pm-11:05 pm
2 stops6h 40m
Des Moines
Sat 5/16
5:35 am-11:35 pm
2 stops17h 00m
$369
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Louisville to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Des Moines in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Louisville with our price prediction graph.
SDF-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Des Moines
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 31, 2026.
Read through reviews of airlines operating flights from Louisville to Des Moines, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Ankeny
Boone
West Des Moines
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 31, 2026.
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Louisville and Des Moines flights
Browse other Louisville and Des Moines flight options. Last updated on March 31, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on March 31, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Louisville to Des Moines
Discover the top 3 airlines that operate flights from Louisville to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$105 | Average$276 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$158 | Average$241 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$386 | FlexibilityNo cancel fee | On-time69% |