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Des Moines

$54+ Cheap flights from Indiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
IND — DSM
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Cheap flight deals from Indiana to Des Moines

Keep the following information in mind while searching for Indiana to Des Moines flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$170
(Kiwi.com)

One-way from

$54
(Frontier)

Popular in

April

Cheapest in

January

Average price

$314
Provider with most accurate pricing for Indianapolis-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Des Moines flights.
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From Indiana to Des Moines
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One-way flight from Indiana to Des Moines
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Highest demand for flights based on searches. 4% potential increase in price ($18 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Indiana to Des Moines

Cheapest flights from Indiana to Des Moines
Explore the most affordable flight options available from Indiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amORD - DSM
1 stop7h 56mMultiple Airlines
Sun 11/99:03 pmDSM - ORD
1 stop13h 39mMultiple Airlines
Deal found 10/12$170
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/611:46 amORD - DSM
Nonstop1h 30mAmerican Airlines
Sun 11/94:02 pmDSM - ORD
Nonstop1h 32mAmerican Airlines
Deal found 10/13$189
This Frontier deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amORD - DSM
1 stop7h 47mFrontier
Mon 11/172:32 pmDSM - ORD
1 stop9h 43mFrontier
Deal found 10/11$191
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:59 pmORD - DSM
Nonstop1h 20mUnited Airlines
Mon 11/33:15 pmDSM - ORD
Nonstop1h 31mUnited Airlines
Deal found 10/12$194
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:55 pmORD - DSM
Nonstop1h 28mAmerican Airlines
Sat 11/111:58 amDSM - ORD
Nonstop1h 33mAmerican Airlines
Deal found 10/12$199
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amORD - DSM
1 stop4h 20mDelta
Fri 11/286:17 amDSM - ORD
1 stop6h 27mDelta
Deal found 10/12$209
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:00 pmMDW - DSM
1 stop4h 35mSouthwest
Sun 11/95:45 amDSM - MDW
1 stop4h 10mSouthwest
Deal found 10/12$209
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/288:56 amCVG - DSM
1 stop26h 33mMultiple Airlines
Thu 10/302:32 pmDSM - CVG
1 stop10h 07mMultiple Airlines
Deal found 10/12$213
This Southwest deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:15 amMDW - DSM
1 stop6h 55mSouthwest
Mon 11/34:15 pmDSM - MDW
1 stop4h 15mSouthwest
Deal found 10/12$214
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:25 pmORD - DSM
1 stop7h 10mDelta
Sat 11/13:30 pmDSM - ORD
1 stop5h 49mDelta
Deal found 10/12$219
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/289:20 amMDW - DSM
1 stop4h 39mDelta
Sat 11/112:30 pmDSM - MDW
1 stop5h 25mDelta
Deal found 10/12$219
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:05 amCVG - DSM
1 stop8h 47mFrontier
Fri 10/312:32 pmDSM - CVG
1 stop28h 48mFrontier
Deal found 10/12$237

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Indiana to Des Moines that are best for you.

Fly from

Indiana

Fly to

Des Moines

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

1:58 pm-3:32 pm

Nonstop1h 34m

Des Moines

Sun 11/9

6:40 pm-8:31 pm

Nonstop1h 51m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 12/5

8:10 pm-9:37 pm

Nonstop1h 27m

Des Moines

Sun 12/7

6:50 pm-8:25 pm

Nonstop1h 35m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 11/21

10:40 am-12:14 pm

Nonstop1h 34m

Des Moines

Sat 11/22

3:15 pm-4:46 pm

Nonstop1h 31m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 11/10

10:22 pm-11:50 pm

Nonstop1h 28m

Des Moines

Mon 11/17

6:40 pm-8:31 pm

Nonstop1h 51m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 11/8

10:40 am-12:14 pm

Nonstop1h 34m

Des Moines

Sun 11/9

8:02 am-9:35 am

Nonstop1h 33m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sat 11/1

12:59 pm-2:19 pm

Nonstop1h 20m

Des Moines

Mon 11/3

3:15 pm-4:46 pm

Nonstop1h 31m

$194

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 10/28

8:55 pm-10:23 pm

Nonstop1h 28m

Des Moines

Sat 11/1

11:58 am-1:31 pm

Nonstop1h 33m

$199

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 11/6

6:00 am-1:56 pm

1 stop7h 56m

Des Moines

Sun 11/9

9:03 pm-12:15 am

2 stops27h 12m

$200

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 11/26

6:00 am-10:20 am

1 stop4h 20m

Des Moines

Fri 11/28

6:17 am-12:44 pm

1 stop6h 27m

$209

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Sat 11/1

5:15 am-12:10 pm

1 stop6h 55m

Des Moines

Sun 11/2

5:45 am-9:55 am

1 stop4h 10m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 56 results
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Best time to book a flight from Indiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Des Moines

What is the cheapest month to book a flight from Indiana to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $166). Flying from Indiana to Des Moines in June is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to DSM?

Find hourly flight availability from Indiana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

When flying from Indiana to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 11% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Indiana?

    For a flight from Indiana to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Indiana to Des Moines?

    Airlines like American Airlines, United Airlines, and Southwest fly from Indiana to Des Moines in about 1h 27m. The time it takes to get you to your destination can typically vary by up to 5h 28m. The distance from Indiana to Des Moines is about 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Indiana to Des Moines one-way?

    The cheapest airlines for a one-way flight from Indiana to Des Moines are Frontier ($100), Delta ($105), and Southwest ($105).

  • What are the most popular routes from Indiana to Des Moines?

    Most travelers choose Chicago O'Hare Intl - Des Moines, Chicago Midway - Des Moines or Cincinnati Cinci./N. Kentucky - Des Moines when deciding on the best route from Indiana to Des Moines.

  • Can I find deals for flights from Indiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Indiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Des Moines.

  • Can I find deals for business class flights from Indiana to Des Moines?

    Yes. Cheapflights offers flight deals from Indiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $166). Flying from Indiana to Des Moines in June is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Indiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Des Moines

Discover the top 3 airlines that operate flights from Indiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$200Average$382FlexibilityNo cancel feeOn-time71%
DeltaCheapest$213Average$318FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$230Average$351FlexibilityNo cancel feeOn-time69%

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