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Des Moines

$75+ Cheap flights from Indiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
IND — DSM
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Indiana to Des Moines

Keep the following information in mind while searching for Indiana to Des Moines flight deals. Data was last updated August 18, 2025.

Round-trip from

$149
(Priceline)

One-way from

$75
(Priceline)

Popular in

April

Cheapest in

January

Average price

$392
From Indiana to Des Moines
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One-way flight from Indiana to Des Moines
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Highest demand for flights based on searches. 0% potential increase in price ($0 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Indiana to Des Moines

Cheapest flights from Indiana to Des Moines
Explore the most affordable flight options available from Indiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Priceline deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/146:00 amORD - DSM
1 stop7h 40mFrontier
Fri 9/192:25 pmDSM - ORD
1 stop9h 34mFrontier
Deal found 8/18$149
This Priceline deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:05 amCVG - DSM
1 stop8h 42mFrontier
Sun 11/162:32 pmDSM - CVG
1 stop10h 07mFrontier
Deal found 8/17$151
This Priceline deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:00 amORD - DSM
1 stop7h 40mFrontier
Thu 9/182:25 pmDSM - ORD
1 stop9h 34mFrontier
Deal found 8/16$168
This Justfly.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:00 amORD - DSM
1 stop7h 40mFrontier
Sun 9/142:25 pmDSM - ORD
1 stop19h 12mFrontier
Deal found 8/18$171
This Priceline deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:00 amORD - DSM
1 stop7h 40mFrontier
Sun 9/72:25 pmDSM - ORD
1 stop9h 34mFrontier
Deal found 8/16$184
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1110:47 amORD - DSM
Nonstop1h 27mUnited Airlines
Sun 9/143:25 pmDSM - ORD
Nonstop1h 33mUnited Airlines
Deal found 8/17$189
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/91:26 pmORD - DSM
1 stop6h 31mMultiple Airlines
Sun 10/128:47 pmDSM - ORD
1 stop26h 54mMultiple Airlines
Deal found 8/16$190
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/62:00 pmORD - DSM
Nonstop1h 33mAmerican Airlines
Sun 9/76:09 pmDSM - ORD
Nonstop1h 41mAmerican Airlines
Deal found 8/16$191
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/51:25 pmORD - DSM
Nonstop1h 31mAmerican Airlines
Sun 9/75:00 amDSM - ORD
Nonstop1h 28mAmerican Airlines
Deal found 8/17$194
This Priceline deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/36:00 amORD - DSM
1 stop7h 40mFrontier
Sun 10/52:25 pmDSM - ORD
1 stop9h 34mFrontier
Deal found 8/17$195
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/211:11 amORD - DSM
Nonstop1h 28mAmerican Airlines
Sat 9/67:08 amDSM - ORD
Nonstop1h 31mAmerican Airlines
Deal found 8/18$199
This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:08 pmMDW - DSM
1 stop3h 44mDelta
Thu 10/236:05 amDSM - MDW
1 stop6h 23mDelta
Deal found 8/16$203

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Indiana to Des Moines that are best for you.

Fly from

Indiana

Fly to

Des Moines

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 10/22

7:15 am-1:52 pm

1 stop6h 37m

Des Moines

Thu 10/23

2:37 pm-11:53 pm

1 stop9h 16m

$149

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Sun 9/14

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Fri 9/19

2:25 pm-11:59 pm

1 stop9h 34m

$149

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 9/15

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Mon 9/22

2:25 pm-11:59 pm

1 stop9h 34m

$149

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 9/18

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Fri 9/19

2:25 pm-11:59 pm

1 stop9h 34m

$149

CincinnatiDes Moines

CVG - DSM

CVGDSM

Cincinnati Cinci./N. Kentucky

Fri 11/14

6:05 am-1:47 pm

1 stop8h 42m

Des Moines

Sun 11/16

2:32 pm-1:39 am

1 stop10h 07m

$151

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 9/15

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Thu 9/18

2:25 pm-11:59 pm

1 stop9h 34m

$168

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 9/12

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Sun 9/14

2:25 pm-9:37 am

1 stop19h 12m

$171

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Fri 9/12

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Mon 9/15

2:25 pm-11:59 pm

1 stop9h 34m

$171

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 9/22

6:00 am-1:40 pm

1 stop7h 40m

Des Moines

Thu 9/25

2:25 pm-11:59 pm

1 stop9h 34m

$171

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 10/22

1:08 pm-4:52 pm

1 stop3h 44m

Des Moines

Thu 10/23

6:05 am-12:28 pm

1 stop6h 23m

$203

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Des Moines

What is the cheapest month to book a flight from Indiana to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $336). Flying from Indiana to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to DSM?

Find hourly flight availability from Indiana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Indiana to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Indiana?

    For a flight from Indiana to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Indiana to Des Moines?

    Airlines like Frontier, Delta, and Southwest fly from Indiana to Des Moines in about 3h 44m. The time it takes to get you to your destination can typically vary by up to 2h 53m. The distance from Indiana to Des Moines is about 305 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Indiana to Des Moines one-way?

    The cheapest airlines for a one-way flight from Indiana to Des Moines are Frontier ($75), Delta ($99), and Southwest ($104).

  • What are the most popular routes from Indiana to Des Moines?

    Most travelers choose Chicago O'Hare Intl - Des Moines, Chicago Midway - Des Moines or Fort Wayne - Des Moines when deciding on the best route from Indiana to Des Moines.

  • Can I find deals for flights from Indiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Indiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Des Moines.

  • Can I find deals for business class flights from Indiana to Des Moines?

    Yes. Cheapflights offers flight deals from Indiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $336). Flying from Indiana to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Alternative routes for Indiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Des Moines

Discover the top 3 airlines that operate flights from Indiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$340FlexibilityNo cancel feeOn-time71%
DeltaCheapest$213Average$318FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$241Average$401FlexibilityNo cancel feeOn-time69%

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