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Des Moines

$65+ Cheap flights from Indiana to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
IND — DSM
Jan 5 — Jan 121
Mon 1/5
Mon 1/12
1 adult, Economy
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Cheap flight deals from Indiana to Des Moines

Cheapest flights from Indiana to Des Moines
Explore the most affordable flight options available from Indiana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 6, 2025.

This United Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:10 pmORD - DSM
Nonstop1h 30mUnited Airlines
Wed 12/318:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Deal found 12/5$189
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/251:29 pmORD - DSM
Nonstop1h 24mAmerican Airlines
Mon 12/296:52 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Deal found 12/4$190
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:40 amORD - DSM
Nonstop1h 35mAmerican Airlines
Tue 12/306:52 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Deal found 12/4$204
This American Airlines deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:36 pmORD - DSM
Nonstop1h 33mAmerican Airlines
Wed 1/217:00 amDSM - ORD
Nonstop1h 44mAmerican Airlines
Deal found 12/5$234
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:10 pmORD - DSM
Nonstop1h 30mUnited Airlines
Sun 12/218:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Deal found 12/4$235
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:45 amORD - DSM
Nonstop1h 29mAmerican Airlines
Tue 12/306:52 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Deal found 12/4$239
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:25 pmORD - DSM
Nonstop1h 32mAmerican Airlines
Sat 12/205:40 amDSM - ORD
Nonstop1h 46mAmerican Airlines
Deal found 12/4$249
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:31 pmORD - DSM
Nonstop1h 34mUnited Airlines
Mon 12/298:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Deal found 12/4$251
This Delta deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:01 pmORD - DSM
1 stop4h 01mDelta
Mon 12/2912:08 pmDSM - ORD
1 stop5h 39mDelta
Deal found 12/4$254
This Delta deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/131:14 pmMDW - DSM
1 stop3h 44mDelta
Wed 1/2112:25 pmDSM - MDW
1 stop5h 30mDelta
Deal found 12/5$254
This Mytrip deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:15 pmCVG - DSM
1 stop6h 17mAllegiant Air
Wed 12/246:00 amDSM - CVG
1 stop12h 50mAllegiant Air
Deal found 12/5$257
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:31 pmORD - DSM
Nonstop1h 34mUnited Airlines
Sun 1/46:46 pmDSM - ORD
Nonstop1h 39mUnited Airlines
Deal found 12/4$267

Find flight deals from Indiana to Des Moines

Keep the following information in mind while searching for Indiana to Des Moines flight deals. Data was last updated December 6, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$161
(Delta)

One-way from

$65
(Southwest)

Popular in

November

Cheapest in

January

Average price

$388
Provider with most accurate pricing for Indianapolis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Des Moines flights.
Search Deals
From Indiana to Des Moines
Search Deals
One-way flight from Indiana to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($63 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 6, 2025.
Use the filters below to find and compare flights from Indiana to Des Moines that are best for you.

Fly from

Indiana

Fly to

Des Moines

Route

Depart

Return

Price

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 1/8

6:50 am-11:24 am

1 stop4h 34m

Des Moines

Sat 1/10

6:24 am-1:08 pm

1 stop6h 44m

$161

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Mon 12/29

8:10 pm-9:40 pm

Nonstop1h 30m

Des Moines

Wed 12/31

8:00 am-9:38 am

Nonstop1h 38m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 2/5

9:40 am-11:12 am

Nonstop1h 32m

Des Moines

Sat 2/7

5:01 pm-6:48 pm

Nonstop1h 47m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 3/26

1:10 pm-2:37 pm

Nonstop1h 27m

Des Moines

Sat 3/28

6:49 pm-8:25 pm

Nonstop1h 36m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Tue 1/13

6:15 am-10:19 am

1 stop4h 04m

Des Moines

Wed 1/14

4:21 pm-9:43 pm

1 stop5h 22m

$189

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Thu 3/26

6:15 am-10:22 am

1 stop4h 07m

Des Moines

Sat 3/28

7:00 am-11:35 am

1 stop4h 35m

$209

ChicagoDes Moines

ORD - DSM

ORDDSM

Chicago O'Hare Intl

Wed 1/14

8:50 am-3:41 pm

1 stop6h 51m

Des Moines

Wed 1/21

6:24 am-1:18 pm

1 stop6h 54m

$209

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Wed 1/14

9:50 am-3:41 pm

1 stop5h 51m

Des Moines

Wed 1/21

6:54 am-1:09 pm

1 stop6h 15m

$209

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Mon 3/2

4:15 pm-9:20 pm

1 stop5h 05m

Des Moines

Thu 3/5

4:20 pm-5:40 pm

Nonstop1h 20m

$214

ChicagoDes Moines

MDW - DSM

MDWDSM

Chicago Midway

Thu 2/5

1:15 pm-10:15 pm

2 stops9h 00m

Des Moines

Sat 2/7

5:45 am-11:45 am

1 stop6h 00m

$214

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Des Moines

What is the cheapest month to book a flight from Indiana to Des Moines?

Currently, April is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $166). Flying from Indiana to Des Moines in June is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to DSM?

Find hourly flight availability from Indiana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 6, 2025.

When flying from Indiana to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 11% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Indiana?

    For a flight from Indiana to Des Moines, you will be flying into Des Moines. Des Moines (DSM) is just 3.6 mi from the center of the city.

  • How long is the flight from Indiana to Des Moines?

    Airlines like Delta, United Airlines, and American Airlines fly from Indiana to Des Moines in about 1h 30m. The time it takes to get you to your destination can typically vary by up to 3h 04m. The distance from Indiana to Des Moines is about 298 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Indiana to Des Moines?

    Most travelers choose Chicago O'Hare Intl - Des Moines, Chicago Midway - Des Moines or Louisville Intl - Des Moines when deciding on the best route from Indiana to Des Moines.

  • Can I find deals for flights from Indiana to Des Moines that include hotel bookings?

    Yes. In addition to deals on Indiana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Des Moines.

  • Can I find deals for business class flights from Indiana to Des Moines?

    Yes. Cheapflights offers flight deals from Indiana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Des Moines?

    Currently, April is the cheapest month in which you can book a flight from Indiana to Des Moines (average of $166). Flying from Indiana to Des Moines in June is currently the most expensive (average of $300). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Indiana to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Indiana to Des Moines

Discover the top 3 airlines that operate flights from Indiana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$200Average$318FlexibilityNo cancel feeOn-time71%
DeltaCheapest$213Average$307FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$228Average$346FlexibilityNo cancel feeOn-time69%

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