HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$100+ Cheap flights from Charlotte to Des Moines (CLT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — DSM
févr. 25 — mars 41
mer. 2/25
mer. 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charlotte to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.
Cheapflights Tip: The best prices from Charlotte Douglas to Des Moines are usually found in September or March, booked 65 days in advance, depart on a Wednesday or Sunday and return on a Wednesday

Cheap flight deals from Charlotte to Des Moines

Cheapest flights from Charlotte to Des Moines
Explore the most affordable flight options available from Charlotte to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on janvier 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 4/19:22 pm
CLT
-
DSM
1 stop26h 29m
Multiple Airlines
ven. 5/110:23 am
DSM
-
CLT
1 stop22h 54m
Multiple Airlines
Deal found 1/24$269
This Southwest deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/287:35 am
CLT
-
DSM
1 stop4h 50m
Southwest
mar. 5/123:15 pm
DSM
-
CLT
1 stop4h 40m
Southwest
Deal found 1/25$349
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/2811:22 am
CLT
-
DSM
Nonstop2h 30m
American Airlines
mar. 5/121:38 pm
DSM
-
CLT
Nonstop2h 24m
American Airlines
Deal found 1/25$351
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 2/146:43 pm
CLT
-
DSM
2 stops24h 49m
Multiple Airlines
dim. 2/223:32 pm
DSM
-
CLT
1 stop15h 54m
Multiple Airlines
Deal found 1/24$353
This Southwest deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/235:05 pm
CLT
-
DSM
1 stop6h 25m
Southwest
lun. 3/25:20 am
DSM
-
CLT
2 stops10h 10m
Southwest
Deal found 1/24$354
This Southwest deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 1/291:35 pm
CLT
-
DSM
1 stop6h 45m
Southwest
sam. 1/315:45 am
DSM
-
CLT
1 stop8h 00m
Southwest
Deal found 1/25$364
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/85:30 am
CLT
-
DSM
1 stop5h 44m
Delta
sam. 7/1111:04 am
DSM
-
CLT
1 stop7h 17m
Delta
Deal found 1/26$371

Find flight deals from Charlotte to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated janvier 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$269
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$431

Good round-trip deal

$376 or less
Provider with most accurate pricing for Charlotte Douglas-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Des Moines flights.
Search Deals
From Charlotte Douglas to Des Moines
Search Deals
One-way flight from Charlotte Douglas to Des Moines
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Charlotte Douglas to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charlotte to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janvier 26, 2026.
Use the filters below to find and compare flights from Charlotte to Des Moines that are best for you.

Fly from

Charlotte

Fly to

Des Moines

Route

Depart

Return

Price

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mer. 4/1

1:24 pm-1:46 pm

2 stops25h 22m

Des Moines

ven. 5/1

10:23 am-10:17 am

1 stop22h 54m

$300

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mar. 4/28

11:22 am-12:52 pm

Nonstop2h 30m

Des Moines

mar. 5/12

1:38 pm-5:02 pm

Nonstop2h 24m

$351

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mar. 4/28

6:20 pm-10:10 pm

1 stop4h 50m

Des Moines

mar. 5/12

6:55 am-6:40 pm

2 stops10h 45m

$354

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

lun. 2/23

12:55 pm-10:30 pm

2 stops10h 35m

Des Moines

lun. 3/2

5:20 am-4:30 pm

2 stops10h 10m

$359

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mer. 7/8

11:45 am-5:42 pm

1 stop6h 57m

Des Moines

sam. 7/11

2:15 pm-9:05 pm

1 stop5h 50m

$371

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

sam. 2/28

10:45 am-7:15 pm

2 stops9h 30m

Des Moines

dim. 3/1

6:10 am-7:45 pm

2 stops12h 35m

$379

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

mer. 4/1

11:30 am-1:07 pm

Nonstop2h 37m

Des Moines

ven. 5/1

7:05 am-10:30 am

Nonstop2h 25m

$381

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

sam. 2/28

11:40 am-1:17 pm

Nonstop2h 37m

Des Moines

dim. 3/1

2:02 pm-5:25 pm

Nonstop2h 23m

$381

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

dim. 2/22

5:13 pm-6:32 pm

1 stop26h 19m

$100

CharlotteDes Moines

CLT - DSM

CLTDSM

Charlotte Douglas

jeu. 4/23

8:56 am-4:00 pm

1 stop8h 04m

$131

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 16 results
1
2

Compare providers for flights from Charlotte to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charlotte-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charlotte-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charlotte-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charlotte-Des Moines flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charlotte to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charlotte with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charlotte to Des Moines

How far ahead should I book a flight from Charlotte to Des Moines?

Use this chart to determine the optimal time to book a round-trip flight from Charlotte to Des Moines. Price data was last updated on January 23, 2026.

To ensure you get the cheapest price possible for a flight from Charlotte to Des Moines, you should look to book at least 63 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Charlotte to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Charlotte to Des Moines (average of $208). Flying from Charlotte to Des Moines in November is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLT to DSM?

Find hourly flight availability from Charlotte to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated janvier 26, 2026.

One of the essential ways to save on airfare from Charlotte to Des Moines is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 10% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated janvier 26, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Charlotte to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,111 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charlotte to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Charlotte to Des Moines?

    If you wish to fly to Des Moines from Charlotte, then you need to book flights from Charlotte Douglas to Des Moines. There is 1 flight from Douglas (CLT) to Des Moines (DSM) per day to choose from. Flights to Des Moines from Douglas are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 2h 34m is how long a nonstop flight from Charlotte to Des Moines typically takes.

  • How popular is this Charlotte to Des Moines flight route?

    Flights from Charlotte Douglas to Des Moines have been viewed 1 times in the past calendar month.

  • How long is the flight from Charlotte to Des Moines?

    For as low as $351, American Airlines can have you in Des Moines from Charlotte in 2h 30m. Charlotte and Des Moines are separated by a distance of 813 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Charlotte to Des Moines round-trip?

    Currently priced at $254, Delta will fly you from Charlotte to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $257. Delta is currently priced 39% below the average price you’ll pay for this route.

  • What are the cheapest flights from Charlotte to Des Moines?

    Looking for the cheapest flight from Charlotte to Des Moines? While on average our users pay $413, our data indicates the cheapest price to be $331. The most popular route (Charlotte Douglas - Des Moines), is priced around $269.

  • Can I find deals for flights from Charlotte to Des Moines that include hotel bookings?

    Yes. In addition to deals on Charlotte to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charlotte to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charlotte to Des Moines.

  • Can I find deals for business class flights from Charlotte to Des Moines?

    Yes. Cheapflights offers flight deals from Charlotte to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charlotte to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Charlotte to Des Moines (average of $208). Flying from Charlotte to Des Moines in November is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charlotte to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Omaha flights
Raleigh to Omaha flights
Charlotte to Cedar Rapids flights
Charlotte to Moline flights
Norfolk to Omaha flights
Raleigh to Cedar Rapids flights
Norfolk to Moline flights
Raleigh to Des Moines flights
Greensboro to Omaha flights
Myrtle Beach to Moline flights
Knoxville to Omaha flights
Myrtle Beach to Des Moines flights
Norfolk to Des Moines flights
Knoxville to Des Moines flights
Jacksonville to Cedar Rapids flights
Myrtle Beach to Omaha flights
Myrtle Beach to Cedar Rapids flights
Asheville to Omaha flights
Wilmington to Des Moines flights
Raleigh to Dubuque flights
Wilmington to Moline flights
Asheville to Des Moines flights
Asheville to Cedar Rapids flights
Fayetteville to Omaha flights
Wilmington to Omaha flights
Raleigh to Moline flights
Wilmington to Cedar Rapids flights
Greensboro to Des Moines flights
Norfolk to Cedar Rapids flights
Greensboro to Cedar Rapids flights
Charlotte to Sioux City flights
Asheville to Moline flights
Charlotte to Waterloo flights
Greensboro to Moline flights
Knoxville to Moline flights
Fayetteville to Des Moines flights
Raleigh to Sioux City flights
New Bern to Omaha flights
New Bern to Cedar Rapids flights
Norfolk to Waterloo flights
Norfolk to La Crosse flights
Charlotte to Dubuque flights
Fayetteville to Moline flights
Raleigh to La Crosse flights
Fayetteville to Waterloo flights
Fayetteville to Cedar Rapids flights
Charlotte to La Crosse flights
Greenville to Moline flights

Top 2 airlines flying from Charlotte to Des Moines

Discover the top 2 airlines that operate flights from Charlotte to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated janvier 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$254Average$418FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$257Average$434FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.