$328+ Cheap flights from Des Moines to Columbia, MO (DSM - COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — COU
Oct 17 — Oct 241
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Columbia
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to ColumbiaExplore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
Explore the most affordable flight options available from Des Moines to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:00 am -
1 stop6h 38m
Sat 10/311:19 am -
1 stop6h 29m
Deal found 9/14![United Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:00 am -
1 stop7h 08m
Mon 10/511:15 am -
1 stop6h 33m
Deal found 9/16![United Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:24 am -
1 stop4h 15m
Sun 9/2711:15 am -
1 stop6h 33m
Deal found 9/14![United Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 pm -
1 stop4h 13m
Mon 11/303:00 pm -
1 stop6h 55m
Deal found 9/16![United Airlines logo]()
$478
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:31 pm -
1 stop14h 27m
Sun 10/256:00 am -
1 stop50h 56m
Deal found 9/15![American Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
2 stops28h 39m
Sun 10/253:00 pm -
1 stop6h 55m
Deal found 9/15![United Airlines logo]()
$797
Best flights from Des Moines to ColumbiaDiscover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
Discover carefully curated flight deals from Des Moines to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 17, 2026.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:00 am -
1 stop6h 38m
Sat 10/311:19 am -
1 stop6h 29m
Deal found 9/14![United Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:31 pm -
1 stop14h 27m
Sun 10/256:00 am -
1 stop50h 56m
Deal found 9/15![American Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 pm -
1 stop4h 13m
Mon 11/303:00 pm -
1 stop6h 55m
Deal found 9/16![United Airlines logo]()
$478
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
2 stops28h 39m
Sun 10/253:00 pm -
1 stop6h 55m
Deal found 9/15![United Airlines logo]()
$797
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:45 am -
2 stops9h 23m
Mon 10/511:15 am -
1 stop6h 33m
Deal found 9/16![United Airlines logo]()
$868
Last-minute flights from Des Moines to ColumbiaDiscover last-minute flight deals from Des Moines to Columbia. Data last updated September 17, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Columbia. Data last updated September 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:24 am -
1 stop4h 15m
Sun 9/2711:15 am -
1 stop6h 33m
Deal found 9/14![United Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:00 am -
1 stop6h 38m
Sat 10/311:19 am -
1 stop6h 29m
Deal found 9/14![United Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:00 am -
1 stop7h 08m
Mon 10/511:15 am -
1 stop6h 33m
Deal found 9/16![United Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:31 pm -
1 stop14h 27m
Sun 10/256:00 am -
1 stop50h 56m
Deal found 9/15![American Airlines logo]()
$551
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am -
2 stops28h 39m
Sun 10/253:00 pm -
1 stop6h 55m
Deal found 9/15![United Airlines logo]()
$797
One-way flights from Des Moines to ColumbiaSearch for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
Search for one-way flight options from Des Moines to Columbia. Find affordable one-way fares based on user searches. Data last updated September 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:58 pm -
2 stops26h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:00 am -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![United Airlines logo]()
$358
Find flight deals from Des Moines to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $328 (United Airlines) |
One-way from | $328 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 17, 2026.
Use the filters below to find and compare flights from Des Moines to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Thu 9/24
1:58 pm-4:41 pm
2 stops26h 43m
Columbia Regional
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$328
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Tue 9/29
8:00 am-2:38 pm
1 stop6h 38m
Columbia Regional
Sat 10/3
11:19 am-5:48 pm
1 stop6h 29m
$328
Quickest round-trip
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Thu 9/24
6:00 am-10:39 am
1 stop4h 39m
Columbia Regional
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$358
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Fri 11/20
6:45 pm-10:58 pm
1 stop4h 13m
Columbia Regional
Mon 11/30
3:00 pm-9:55 pm
1 stop6h 55m
$478
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Fri 10/23
7:31 pm-9:58 am
1 stop14h 27m
Columbia Regional
Sun 10/25
6:00 am-8:56 am
1 stop50h 56m
$551
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Fri 10/23
6:00 am-10:39 am
2 stops28h 39m
Columbia Regional
Sun 10/25
3:00 pm-9:55 pm
1 stop6h 55m
$797
Des MoinesColumbia
DSM Des Moines - COU Columbia Regional
DSMCOU
Des Moines
Thu 10/1
5:45 am-3:08 pm
2 stops9h 23m
Columbia Regional
Mon 10/5
11:15 am-5:48 pm
1 stop6h 33m
$868
Sorted by cheapest first
Compare providers for flights from Des Moines to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Des Moines with our price prediction graph.
DSM-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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