$212+ Cheap flights from Florence, SC (FLO) to O'Hare Intl (ORD)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Sep 17 — Sep 241
Round-trip
1 adult, Economy
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Find cheap flights from Florence to O'Hare Intl with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to O'Hare Intl
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Best
Last-minute
One-way
Cheapest flights from Florence to O'Hare IntlExplore the most affordable flight options available from Florence to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
Explore the most affordable flight options available from Florence to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:43 pm -
1 stop4h 55m
Wed 9/234:45 pm -
1 stop5h 13m
Deal found 8/17![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:24 am -
1 stop5h 21m
Thu 9/248:05 am -
1 stop4h 13m
Deal found 8/17![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:24 am -
1 stop6h 50m
Wed 9/166:29 am -
1 stop5h 49m
Deal found 8/18![American Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:43 pm -
1 stop4h 55m
Wed 9/236:29 am -
1 stop5h 49m
Deal found 8/17![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:22 am -
1 stop6h 53m
Wed 9/24:53 pm -
1 stop5h 06m
Deal found 8/14![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:24 am -
1 stop5h 21m
Fri 9/254:45 pm -
1 stop5h 13m
Deal found 8/17![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:22 am -
1 stop6h 53m
Sun 9/67:30 am -
1 stop5h 42m
Deal found 8/18![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:43 pm -
1 stop4h 55m
Sun 9/276:45 am -
1 stop6h 25m
Deal found 8/17![American Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:24 am -
1 stop5h 21m
Sun 9/274:45 pm -
1 stop6h 12m
Deal found 8/17![American Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:22 pm -
1 stop5h 24m
Mon 8/315:49 pm -
1 stop4h 10m
Deal found 8/13![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:22 pm -
1 stop7h 35m
Tue 8/257:30 am -
1 stop6h 26m
Deal found 8/17![American Airlines logo]()
$498
Best flights from Florence to O'Hare IntlDiscover carefully curated flight deals from Florence to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
Discover carefully curated flight deals from Florence to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:43 pm -
1 stop4h 55m
Wed 9/234:45 pm -
1 stop5h 13m
Deal found 8/17![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:24 am -
1 stop5h 21m
Thu 9/248:05 am -
1 stop4h 13m
Deal found 8/17![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:24 am -
1 stop6h 50m
Fri 9/258:05 am -
1 stop4h 13m
Deal found 8/17![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:22 am -
1 stop6h 53m
Sat 9/58:54 am -
1 stop4h 18m
Deal found 8/17![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:22 am -
1 stop6h 53m
Wed 9/24:53 pm -
1 stop5h 06m
Deal found 8/14![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:22 am -
1 stop6h 53m
Tue 9/17:30 am -
1 stop6h 26m
Deal found 8/13![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:43 pm -
1 stop4h 55m
Sun 9/276:45 am -
1 stop6h 25m
Deal found 8/17![American Airlines logo]()
$469
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:22 am -
1 stop5h 29m
Fri 9/46:49 am -
1 stop7h 07m
Deal found 8/16![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/141:43 pm -
1 stop6h 55m
Mon 9/214:45 pm -
1 stop5h 13m
Deal found 8/15![American Airlines logo]()
$615
Last-minute flights from Florence to O'Hare IntlDiscover last-minute flight deals from Florence to O'Hare Intl. Data last updated August 18, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to O'Hare Intl. Data last updated August 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:22 pm -
1 stop7h 35m
Tue 8/257:30 am -
1 stop6h 26m
Deal found 8/17![American Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:22 pm -
1 stop5h 24m
Mon 8/315:49 pm -
1 stop4h 10m
Deal found 8/13![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:22 am -
1 stop6h 53m
Wed 9/24:53 pm -
1 stop5h 06m
Deal found 8/14![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:22 am -
1 stop6h 53m
Sun 9/67:30 am -
1 stop5h 42m
Deal found 8/18![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:24 am -
1 stop6h 50m
Wed 9/166:29 am -
1 stop5h 49m
Deal found 8/18![American Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:43 pm -
1 stop4h 55m
Wed 9/234:45 pm -
1 stop5h 13m
Deal found 8/17![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:43 pm -
1 stop4h 55m
Wed 9/236:29 am -
1 stop5h 49m
Deal found 8/17![American Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:24 am -
1 stop5h 21m
Fri 9/254:45 pm -
1 stop5h 13m
Deal found 8/17![American Airlines logo]()
$459
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:24 am -
1 stop5h 21m
Sun 9/274:45 pm -
1 stop6h 12m
Deal found 8/17![American Airlines logo]()
$481
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:24 am -
1 stop5h 21m
Thu 9/248:05 am -
1 stop4h 13m
Deal found 8/17![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:43 pm -
1 stop4h 55m
Sun 9/276:45 am -
1 stop6h 25m
Deal found 8/17![American Airlines logo]()
$469
One-way flights from Florence to O'Hare IntlSearch for one-way flight options from Florence to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
Search for one-way flight options from Florence to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated August 18, 2026.
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/235:05 am -
1 stop5h 00m
Deal found 8/17![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:19 pm -
1 stop5h 32m
Deal found 8/16![American Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:34 pm -
1 stop6h 17m
Deal found 8/16![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/122:34 pm -
1 stop10h 34m
Deal found 8/16![American Airlines logo]()
$887
Find flight deals from Florence to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
One-way from | $274 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2026.
Use the filters below to find and compare flights from Florence to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 9/19
1:43 pm-5:38 pm
1 stop4h 55m
Chicago O'Hare Intl
Wed 9/23
4:45 pm-10:58 pm
1 stop5h 13m
$435
Quickest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 9/19
6:24 am-10:45 am
1 stop5h 21m
Chicago O'Hare Intl
Thu 9/24
8:05 am-1:18 pm
1 stop4h 13m
$435
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 9/19
6:24 am-12:14 pm
1 stop6h 50m
Chicago O'Hare Intl
Fri 9/25
8:05 am-1:18 pm
1 stop4h 13m
$447
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Tue 9/1
6:22 am-12:15 pm
1 stop6h 53m
Chicago O'Hare Intl
Sat 9/5
8:54 am-2:12 pm
1 stop4h 18m
$449
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 8/29
6:22 am-12:15 pm
1 stop6h 53m
Chicago O'Hare Intl
Wed 9/2
4:53 pm-10:59 pm
1 stop5h 06m
$449
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Fri 8/28
6:22 am-12:15 pm
1 stop6h 53m
Chicago O'Hare Intl
Tue 9/1
7:30 am-2:56 pm
1 stop6h 26m
$468
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 9/19
1:43 pm-5:38 pm
1 stop4h 55m
Chicago O'Hare Intl
Sun 9/27
6:45 am-2:10 pm
1 stop6h 25m
$469
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 8/31
6:22 am-10:51 am
1 stop5h 29m
Chicago O'Hare Intl
Fri 9/4
6:49 am-2:56 pm
1 stop7h 07m
$487
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 9/14
1:43 pm-7:38 pm
1 stop6h 55m
Chicago O'Hare Intl
Mon 9/21
4:45 pm-10:58 pm
1 stop5h 13m
$615
Cheapest one-way
Quickest one-way
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sun 9/27
5:09 am-9:00 am
1 stop4h 51m
$212
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Florence to O'Hare Intl
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to O'Hare Intl in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Florence, South Carolina-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, South Carolina-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Florence with our price prediction graph.
FLO-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Florence to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locationsBenton Harbor
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