$274+ Cheap flights from Florence, SC (FLO) to O'Hare Intl (ORD)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Oct 23 — Oct 301
Round-trip
1 adult, Economy
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Find cheap flights from Florence to O'Hare Intl with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to O'Hare Intl
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Last-minute
One-way
Cheapest flights from Florence to O'Hare IntlExplore the most affordable flight options available from Florence to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
Explore the most affordable flight options available from Florence to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 23, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:43 pm -
1 stop4h 55m
Wed 10/76:29 am -
1 stop6h 40m
Deal found 9/18![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:35 pm -
1 stop6h 28m
Mon 11/306:49 pm -
1 stop4h 05m
Deal found 9/19![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:37 pm -
1 stop4h 59m
Fri 12/49:00 am -
1 stop4h 10m
Deal found 9/18![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:24 am -
1 stop5h 36m
Mon 11/94:40 pm -
1 stop5h 19m
Deal found 9/18![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:34 pm -
1 stop6h 17m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 9/21![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop7h 15m
Sun 11/294:58 pm -
1 stop5h 56m
Deal found 9/21![American Airlines logo]()
$521
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:34 pm -
1 stop4h 17m
Fri 10/98:05 am -
1 stop5h 04m
Deal found 9/20![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:35 pm -
1 stop6h 24m
Sat 1/26:47 pm -
1 stop4h 10m
Deal found 9/19![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:09 am -
1 stop4h 50m
Tue 12/18:05 am -
1 stop5h 04m
Deal found 9/19![American Airlines logo]()
$563
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:35 pm -
1 stop6h 28m
Sat 11/284:58 pm -
1 stop5h 56m
Deal found 9/21![American Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:00 am -
1 stop5h 26m
Sat 11/284:58 pm -
1 stop5h 56m
Deal found 9/21![American Airlines logo]()
$577
Best flights from Florence to O'Hare IntlDiscover carefully curated flight deals from Florence to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
Discover carefully curated flight deals from Florence to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 23, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:43 pm -
1 stop4h 55m
Wed 10/76:29 am -
1 stop6h 40m
Deal found 9/18![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:34 pm -
1 stop6h 17m
Wed 11/49:00 am -
1 stop5h 09m
Deal found 9/20![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:35 pm -
1 stop6h 28m
Mon 11/306:49 pm -
1 stop4h 05m
Deal found 9/21![American Airlines logo]()
$492
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:37 pm -
1 stop4h 59m
Fri 12/49:00 am -
1 stop4h 10m
Deal found 9/19![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:24 am -
1 stop5h 36m
Mon 11/94:40 pm -
1 stop5h 19m
Deal found 9/18![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:34 pm -
1 stop4h 17m
Fri 10/96:29 am -
1 stop6h 40m
Deal found 9/22![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:09 am -
1 stop5h 01m
Sun 10/118:05 am -
1 stop5h 04m
Deal found 9/22![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/292:35 pm -
1 stop6h 24m
Sat 1/26:47 pm -
1 stop4h 10m
Deal found 9/19![American Airlines logo]()
$550
Last-minute flights from Florence to O'Hare IntlDiscover last-minute flight deals from Florence to O'Hare Intl. Data last updated September 23, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to O'Hare Intl. Data last updated September 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:43 pm -
1 stop4h 55m
Wed 10/76:29 am -
1 stop6h 40m
Deal found 9/18![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:34 pm -
1 stop4h 17m
Fri 10/98:05 am -
1 stop5h 04m
Deal found 9/20![American Airlines logo]()
$547
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:34 pm -
1 stop6h 17m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 9/21![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:09 am -
1 stop5h 01m
Sun 10/116:29 am -
2 stops6h 40m
Deal found 9/22![American Airlines logo]()
$755
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
1 stop4h 17m
Sun 10/118:05 am -
1 stop5h 04m
Deal found 9/22![American Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:34 pm -
1 stop6h 17m
Wed 11/46:57 am -
2 stops7h 12m
Deal found 9/20![American Airlines logo]()
$658
One-way flights from Florence to O'Hare IntlSearch for one-way flight options from Florence to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
Search for one-way flight options from Florence to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated September 23, 2026.
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:09 am -
1 stop6h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:34 pm -
2 stops8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![American Airlines logo]()
$609
Find flight deals from Florence to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $489 (American Airlines) |
One-way from | $274 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 23, 2026.
Use the filters below to find and compare flights from Florence to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sun 10/4
5:09 am-10:45 am
1 stop6h 36m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
Quickest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 10/5
2:34 pm-7:51 pm
1 stop6h 17m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$274
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 10/3
1:43 pm-5:38 pm
1 stop4h 55m
Chicago O'Hare Intl
Wed 10/7
6:29 am-2:09 pm
1 stop6h 40m
$489
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Wed 10/28
2:34 pm-7:51 pm
1 stop6h 17m
Chicago O'Hare Intl
Wed 11/4
9:00 am-3:09 pm
1 stop5h 09m
$489
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Wed 11/25
2:35 pm-8:03 pm
1 stop6h 28m
Chicago O'Hare Intl
Mon 11/30
6:49 pm-11:54 pm
1 stop4h 05m
$492
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Wed 12/2
3:37 pm-7:36 pm
1 stop4h 59m
Chicago O'Hare Intl
Fri 12/4
9:00 am-2:10 pm
1 stop4h 10m
$504
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 11/2
6:24 am-11:00 am
1 stop5h 36m
Chicago O'Hare Intl
Mon 11/9
4:40 pm-10:59 pm
1 stop5h 19m
$507
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 10/5
2:34 pm-5:51 pm
1 stop4h 17m
Chicago O'Hare Intl
Fri 10/9
6:29 am-2:09 pm
1 stop6h 40m
$547
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Thu 10/8
5:09 am-9:10 am
1 stop5h 01m
Chicago O'Hare Intl
Sun 10/11
8:05 am-2:09 pm
1 stop5h 04m
$547
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Tue 12/29
2:35 pm-7:59 pm
1 stop6h 24m
Chicago O'Hare Intl
Sat 1/2
6:47 pm-11:57 pm
1 stop4h 10m
$550
Sorted by cheapest first
Compare providers for flights from Florence to O'Hare Intl
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to O'Hare Intl in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Florence, South Carolina-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Florence, South Carolina-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Florence to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Florence with our price prediction graph.
FLO-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Florence to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
Book flights to Chicago O'Hare Intl Airport if you plan to visit one of these locationsBenton Harbor
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