$190+ Cheap flights from Florence, SC (FLO) to Illinois
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Sep 23 — Sep 301
Round-trip
1 adult, Economy
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Find cheap flights from Florence to Illinois with Cheapflights
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Cheapest flights from Florence to IllinoisExplore the most affordable flight options available from Florence to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
Explore the most affordable flight options available from Florence to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 24, 2026.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:35 pm -
1 stop6h 29m
Mon 12/148:05 am -
1 stop6h 04m
Deal found 8/20![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:22 am -
1 stop4h 10m
Mon 9/78:34 am -
1 stop5h 22m
Deal found 8/20![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:22 pm -
1 stop5h 24m
Wed 8/265:49 pm -
1 stop4h 10m
Deal found 8/21![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:22 am -
1 stop6h 53m
Sun 9/67:30 am -
1 stop5h 42m
Deal found 8/19![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:22 pm -
1 stop5h 24m
Mon 8/315:49 pm -
1 stop4h 10m
Deal found 8/22![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:09 am -
1 stop6h 56m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$495
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:09 am -
1 stop5h 01m
Mon 10/126:40 pm -
1 stop4h 17m
Deal found 8/22![American Airlines logo]()
$573
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
1 stop6h 17m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$581
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
1 stop4h 00m
Wed 9/95:00 am -
2 stops7h 18m
Deal found 8/21![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:22 am -
1 stop5h 29m
Tue 8/256:45 am -
2 stops7h 11m
Deal found 8/21![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:22 pm -
2 stops9h 37m
Tue 9/84:24 pm -
1 stop5h 35m
Deal found 8/20![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
1 stop6h 17m
Mon 10/126:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$659
Best flights from Florence to IllinoisDiscover carefully curated flight deals from Florence to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
Discover carefully curated flight deals from Florence to Illinois that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 24, 2026.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:35 pm -
1 stop6h 29m
Mon 12/148:05 am -
1 stop6h 04m
Deal found 8/20![American Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:22 am -
1 stop4h 10m
Mon 9/78:34 am -
1 stop5h 22m
Deal found 8/20![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
1 stop4h 15m
Wed 9/98:05 am -
1 stop4h 13m
Deal found 8/20![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:22 am -
1 stop6h 53m
Sun 9/67:30 am -
1 stop5h 42m
Deal found 8/19![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/69:00 am -
1 stop6h 20m
Thu 9/105:20 am -
1 stop6h 58m
Deal found 8/21![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:22 am -
1 stop6h 53m
Fri 9/115:20 am -
1 stop6h 58m
Deal found 8/23![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:09 am -
1 stop6h 56m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$495
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
1 stop4h 00m
Wed 9/95:00 am -
2 stops7h 18m
Deal found 8/21![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:22 pm -
2 stops9h 37m
Tue 9/84:24 pm -
1 stop5h 35m
Deal found 8/20![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
1 stop6h 17m
Mon 10/126:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$659
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
2 stops8h 26m
Sun 10/116:29 am -
1 stop6h 40m
Deal found 8/22![American Airlines logo]()
$720
Last-minute flights from Florence to IllinoisDiscover last-minute flight deals from Florence to Illinois. Data last updated August 24, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Illinois. Data last updated August 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:22 pm -
1 stop5h 24m
Wed 8/265:49 pm -
1 stop4h 10m
Deal found 8/21![American Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:22 am -
1 stop5h 29m
Tue 8/256:45 am -
2 stops7h 11m
Deal found 8/21![American Airlines logo]()
$631
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:22 pm -
1 stop5h 24m
Mon 8/315:49 pm -
1 stop4h 10m
Deal found 8/22![American Airlines logo]()
$487
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:22 am -
1 stop6h 53m
Sun 9/67:30 am -
1 stop5h 42m
Deal found 8/19![American Airlines logo]()
$468
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/33:22 pm -
2 stops9h 37m
Tue 9/84:24 pm -
1 stop5h 35m
Deal found 8/20![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:22 am -
1 stop4h 10m
Mon 9/78:34 am -
1 stop5h 22m
Deal found 8/20![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
1 stop4h 00m
Wed 9/95:00 am -
2 stops7h 18m
Deal found 8/21![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/59:00 am -
2 stops6h 15m
Wed 9/92:56 pm -
2 stops7h 02m
Deal found 8/20![American Airlines logo]()
$893
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:22 am -
1 stop5h 29m
Fri 9/111:17 pm -
2 stops8h 41m
Deal found 8/23![American Airlines logo]()
$854
One-way flights from Florence to IllinoisSearch for one-way flight options from Florence to Illinois. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
Search for one-way flight options from Florence to Illinois. Find affordable one-way fares based on user searches. Data last updated August 24, 2026.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:43 pm -
1 stop6h 55m
Deal found 8/19![American Airlines logo]()
$190
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:09 am -
1 stop6h 36m
Deal found 8/20![American Airlines logo]()
$212
Find flight deals from Florence to Illinois
Keep the following information in mind while searching for Florence to Illinois flight deals. Data was last updated August 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (American Airlines) |
One-way from | $190 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 24, 2026.
Use the filters below to find and compare flights from Florence to Illinois that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Thu 12/10
2:35 pm-8:04 pm
1 stop6h 29m
Chicago O'Hare Intl
Mon 12/14
8:05 am-3:09 pm
1 stop6h 04m
$355
FlorenceSt. Louis
FLO Florence - STL Lambert-St Louis
FLOSTL
Florence
Fri 9/4
6:22 am-9:32 am
1 stop4h 10m
Lambert-St Louis
Mon 9/7
8:34 am-2:56 pm
1 stop5h 22m
$399
Quickest round-trip
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sat 9/5
9:00 am-12:15 pm
1 stop4h 15m
Chicago O'Hare Intl
Wed 9/9
8:05 am-1:18 pm
1 stop4h 13m
$449
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Wed 9/2
6:22 am-12:15 pm
1 stop6h 53m
Chicago O'Hare Intl
Sun 9/6
7:30 am-2:12 pm
1 stop5h 42m
$468
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Sun 9/6
9:00 am-2:20 pm
1 stop6h 20m
Chicago O'Hare Intl
Thu 9/10
5:20 am-1:18 pm
1 stop6h 58m
$487
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Mon 9/7
6:22 am-12:15 pm
1 stop6h 53m
Chicago O'Hare Intl
Fri 9/11
5:20 am-1:18 pm
1 stop6h 58m
$487
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Thu 10/8
5:09 am-11:05 am
1 stop6h 56m
Chicago O'Hare Intl
Sun 10/11
6:29 am-2:09 pm
1 stop6h 40m
$495
FlorenceSt. Louis
FLO Florence - STL Lambert-St Louis
FLOSTL
Florence
Sat 9/5
9:00 am-12:00 pm
1 stop4h 00m
Lambert-St Louis
Wed 9/9
5:00 am-1:18 pm
2 stops7h 18m
$597
FlorencePeoria
FLO Florence - PIA Greater Peoria
FLOPIA
Florence
Thu 9/3
3:22 pm-11:59 pm
2 stops9h 37m
Greater Peoria
Tue 9/8
4:24 pm-10:59 pm
1 stop5h 35m
$634
FlorenceChicago
FLO Florence - ORD Chicago O'Hare Intl
FLOORD
Florence
Fri 10/9
2:34 pm-7:51 pm
1 stop6h 17m
Chicago O'Hare Intl
Mon 10/12
6:29 am-2:09 pm
1 stop6h 40m
$659
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from Florence to Illinois
Have a flexible travel schedule? Discover the best time to fly to Illinois from Florence with our price prediction graph.
FLO-STL
FLO-ORD
FLO-PIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Illinois
FLO-USIL
FLO-STL
FLO-ORD
FLO-PIA
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Florence to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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