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$170+ Cheap flights from Florence, SC (FLO) to Illinois

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — ORD
Jun 16 — Jun 231
Tue 6/16
Tue 6/23
1 adult, Economy
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Cheap flight deals from Florence to Illinois

Cheapest flights from Florence to Illinois
Explore the most affordable flight options available from Florence to Illinois. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.

This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:24 am
FLO
-
ORD
1 stop6h 52m
American Airlines
Thu 8/135:43 pm
ORD
-
FLO
1 stop5h 15m
American Airlines
Deal found 5/14$342
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:35 pm
FLO
-
ORD
1 stop6h 10m
American Airlines
Tue 6/304:49 pm
ORD
-
FLO
1 stop4h 11m
American Airlines
Deal found 5/12$345
This American Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:35 pm
FLO
-
ORD
1 stop6h 16m
American Airlines
Mon 7/206:30 am
ORD
-
FLO
1 stop6h 40m
American Airlines
Deal found 5/15$357
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/152:35 pm
FLO
-
ORD
1 stop6h 10m
American Airlines
Sun 6/216:29 am
ORD
-
FLO
1 stop6h 41m
American Airlines
Deal found 5/16$379
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:05 am
FLO
-
ORD
1 stop6h 55m
American Airlines
Sat 6/138:00 am
ORD
-
FLO
1 stop5h 10m
American Airlines
Deal found 5/14$387
This deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:37 pm
FLO
-
STL
1 stop3h 57m
American Airlines
Tue 8/1110:22 am
STL
-
FLO
1 stop3h 34m
American Airlines
Deal found 5/12$405
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:35 pm
FLO
-
STL
1 stop3h 45m
American Airlines
Tue 6/27:30 am
STL
-
FLO
1 stop5h 40m
American Airlines
Deal found 5/14$419
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:05 am
FLO
-
ORD
1 stop4h 57m
American Airlines
Mon 6/18:48 am
ORD
-
FLO
1 stop4h 22m
American Airlines
Deal found 5/13$437
This deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:09 am
FLO
-
STL
1 stop4h 22m
American Airlines
Sat 8/86:25 pm
STL
-
FLO
1 stop4h 33m
American Airlines
Deal found 5/12$438
This American Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:24 am
FLO
-
STL
1 stop4h 08m
American Airlines
Sun 8/99:21 am
STL
-
FLO
1 stop3h 51m
American Airlines
Deal found 5/14$453
This deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:37 pm
FLO
-
STL
1 stop3h 57m
American Airlines
Mon 8/1010:22 am
STL
-
FLO
1 stop3h 34m
American Airlines
Deal found 5/12$471
This deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:24 am
FLO
-
STL
1 stop4h 08m
American Airlines
Tue 8/1110:22 am
STL
-
FLO
1 stop3h 34m
American Airlines
Deal found 5/12$474

Find flight deals from Florence to Illinois

Keep the following information in mind while searching for Florence to Illinois flight deals. Data was last updated May 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$342
(American Airlines)

One-way from

$170
(American Airlines)
Provider with most accurate pricing for Florence-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Chicago (CHI) flights.
Search Deals
From Florence to Illinois
Search Deals
One-way flight from Florence to Illinois
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Illinois that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Florence to Illinois that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 8/11

6:24 am-12:16 pm

1 stop6h 52m

Chicago O'Hare Intl

Thu 8/13

5:43 pm-11:58 pm

1 stop5h 15m

$342

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 6/24

5:05 am-11:00 am

1 stop6h 55m

Chicago O'Hare Intl

Tue 6/30

5:00 am-2:10 pm

2 stops8h 10m

$350

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 6/18

5:05 am-9:02 am

1 stop4h 57m

Chicago O'Hare Intl

Sun 6/21

6:29 am-2:10 pm

1 stop6h 41m

$379

FlorenceChicago

FLO - ORD

FLOORD

Florence

Mon 6/15

2:35 pm-7:45 pm

1 stop6h 10m

Chicago O'Hare Intl

Sun 6/21

6:29 am-2:10 pm

1 stop6h 41m

$379

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 6/7

5:05 am-11:00 am

1 stop6h 55m

Chicago O'Hare Intl

Sat 6/13

8:00 am-2:10 pm

1 stop5h 10m

$387

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 5/29

2:35 pm-5:20 pm

1 stop3h 45m

Lambert-St Louis

Tue 6/2

7:30 am-2:10 pm

1 stop5h 40m

$419

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 5/28

5:05 am-9:02 am

1 stop4h 57m

Chicago O'Hare Intl

Mon 6/1

8:48 am-2:10 pm

1 stop4h 22m

$437

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Thu 8/6

5:09 am-8:31 am

1 stop4h 22m

Lambert-St Louis

Sat 8/8

6:25 pm-11:58 pm

1 stop4h 33m

$438

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 5/31

5:05 am-9:02 am

1 stop4h 57m

Chicago O'Hare Intl

Thu 6/4

5:00 am-2:10 pm

2 stops8h 10m

$442

FlorenceSt. Louis

FLO - STL

FLOSTL

Florence

Fri 8/7

6:24 am-9:32 am

1 stop4h 08m

Lambert-St Louis

Sun 8/9

9:21 am-2:12 pm

1 stop3h 51m

$453

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/14

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Florence to Illinois

Have a flexible travel schedule? Discover the best time to fly to Illinois from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Illinois
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Illinois

Get insights into the airlines that provide service to Illinois. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Illinois. Reviews last updated May 17, 2026.
Read through reviews of airlines operating flights from Florence to Illinois, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,662 reviews

Crew

7.9

Entertainment

6.9

Boarding

7.5

Overall

7.1

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.
American Airlines
7.1
Good
11,662 reviews
American Airlines
7.1
Good
11,662 reviews

Crew

7.9

Entertainment

6.9

Boarding

7.5

Overall

7.1

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

BNA - ORD

My flight was 8 hours delayed, so I missed my connecting flight to Dublin. I understand it’s not the staff’s fault but the lack of sympathy and apology was appalling. I had been sat in the airport since 4am until 3pm and they did not seem understanding. Not good. Need better customer service.

Related info for your journey

Find useful and relevant information for your journey from Florence to Illinois. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Illinois?

    Most people fly from Florence (FLO) if they book a flight from Florence to Illinois. Florence is conveniently located just 2.3 mi from Florence’s city center.

  • How long is the flight from Florence, South Carolina to Illinois?

    American Airlines can get you from Florence, South Carolina to Illinois in just under 6h 52m. Your travel time can differ by up to . The distance between Florence, South Carolina and Illinois is about 697 mi.

  • What are the most popular routes from Florence, South Carolina to Illinois?

    When deciding which route to take from Florence, South Carolina to Illinois consider Florence - Chicago O'Hare Intl, Florence - Lambert-St Louis or Florence - Greater Peoria as they are the most popular.

  • Can I find deals for flights from Florence to Illinois that include hotel bookings?

    Yes. In addition to deals on Florence to Illinois flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Illinois?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Illinois.

  • Can I find deals for business class flights from Florence to Illinois?

    Yes. Cheapflights offers flight deals from Florence to Illinois by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Florence to Illinois

Discover the top airline that operate flights from Florence to Illinois. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$176Average$336FlexibilityNo cancel feeOn-time71%

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