HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cartagena

$489+ Cheap flights from Knoxville (TYS) to Cartagena (CTG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CTG
Dec 25 — Jan 11
Thu 12/25
Thu 1/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Cartagena with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Cartagena

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Cartagena (CTG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 25, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$489
(Avianca)
Provider with most accurate pricing for Knoxville McGhee Tyson-Cartagena Rafael Nunez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cartagena Rafael Nunez flights.
Search Deals
From Knoxville McGhee Tyson to Cartagena Rafael Nunez
Search Deals

Find flight deals from Knoxville to Cartagena

Best flights from Knoxville to Cartagena
Discover carefully curated flight deals from Knoxville to Cartagena that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 25, 2025.

This Avianca deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/227:20 pmTYS - CTG
2 stops18h 40mAvianca
Tue 1/276:20 pmCTG - TYS
2 stops16h 37mAvianca
Deal found 11/24$489
This Kiwi.com deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:18 pmTYS - CTG
2 stops18h 57mMultiple Airlines
Tue 1/132:21 pmCTG - TYS
1 stop25h 36mMultiple Airlines
Deal found 11/25$541
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/225:14 pmTYS - CTG
2 stops22h 16mAmerican Airlines
Tue 1/272:30 pmCTG - TYS
1 stop9h 29mAmerican Airlines
Deal found 11/24$568
This Delta deal was found by Cheapflights users on 11/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/252:37 pmTYS - CTG
1 stop23h 40mDelta
Thu 1/293:32 pmCTG - TYS
1 stop8h 13mDelta
Deal found 11/23$598
This American Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/97:11 pmTYS - CTG
2 stops20h 19mAmerican Airlines
Tue 1/134:30 pmCTG - TYS
2 stops19h 01mAmerican Airlines
Deal found 11/25$582

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Cartagena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
Use the filters below to find and compare flights from Knoxville to Cartagena that are best for you.

Fly from

Knoxville

Fly to

Cartagena

Route

Depart

Return

Price

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Thu 1/22

7:20 pm-2:00 pm

2 stops18h 40m

Cartagena Rafael Nunez

Tue 1/27

6:20 pm-10:57 am

2 stops16h 37m

$489

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Fri 1/9

6:18 pm-1:15 pm

2 stops18h 57m

Cartagena Rafael Nunez

Tue 1/13

2:21 pm-3:57 pm

1 stop25h 36m

$541

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Thu 1/22

5:14 pm-3:30 pm

2 stops22h 16m

Cartagena Rafael Nunez

Tue 1/27

2:30 pm-11:59 pm

1 stop9h 29m

$568

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Fri 1/9

7:11 pm-3:30 pm

2 stops20h 19m

Cartagena Rafael Nunez

Tue 1/13

4:30 pm-11:31 am

2 stops19h 01m

$582

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Sun 1/25

2:37 pm-2:17 pm

1 stop23h 40m

Cartagena Rafael Nunez

Thu 1/29

3:32 pm-11:45 pm

1 stop8h 13m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/24

Compare providers for flights from Knoxville to Cartagena

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Cartagena in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Cartagena flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Cartagena flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Cartagena flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Cartagena flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Cartagena flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Cartagena

Have a flexible travel schedule? Discover the best time to fly to Cartagena from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cartagena

Get insights into the airlines that provide service to Cartagena. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cartagena. Reviews last updated November 25, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Cartagena to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Overall

7.2

Food

6.4

Boarding

7.5

Comfort

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Cartagena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Cartagena?

    Airlines like Avianca fly from Knoxville to Cartagena in about 18h 40m. The time it takes to get you to your destination can typically vary by up to . There are 1830 mi between Knoxville and Cartagena.

  • What is the cheapest airline to fly from Knoxville to Cartagena round-trip?

    Currently priced at $537, American Airlines will fly you from Knoxville to Cartagena and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Knoxville to Cartagena that include hotel bookings?

    Yes. In addition to deals on Knoxville to Cartagena flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Cartagena?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cartagena.

  • Can I find deals for business class flights from Knoxville to Cartagena?

    Yes. Cheapflights offers flight deals from Knoxville to Cartagena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Cartagena?

Book flights to Cartagena if you plan to visit one of these locations
Boca Grande

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Knoxville to Cartagena

Discover the top airline that operate flights from Knoxville to Cartagena. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$537Average$791FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.