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Cartagena

$498+ Cheap flights from Knoxville (TYS) to Cartagena (CTG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CTG
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from Knoxville to Cartagena

Cheapest flights from Knoxville to Cartagena
Explore the most affordable flight options available from Knoxville to Cartagena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:36 pm
TYS
-
CTG
1 stop15h 34m
Multiple Airlines
Mon 3/26:00 am
CTG
-
TYS
2 stops12h 31m
Multiple Airlines
Deal found 2/18$498
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:30 am
TYS
-
CTG
1 stop25h 36m
Multiple Airlines
Mon 3/309:51 pm
CTG
-
TYS
2 stops15h 19m
Multiple Airlines
Deal found 2/20$547
This Avianca deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:50 am
TYS
-
CTG
2 stops18h 20m
Avianca
Mon 9/144:00 pm
CTG
-
TYS
2 stops17h 00m
Avianca
Deal found 2/17$572
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:00 am
TYS
-
CTG
1 stop8h 10m
American Airlines
Mon 9/142:05 pm
CTG
-
TYS
2 stops21h 35m
American Airlines
Deal found 2/17$578
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:30 am
TYS
-
CTG
1 stop8h 01m
American Airlines
Sat 4/111:25 pm
CTG
-
TYS
2 stops20h 01m
American Airlines
Deal found 2/17$601
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:00 am
TYS
-
CTG
2 stops10h 15m
American Airlines
Mon 3/301:35 pm
CTG
-
TYS
2 stops21h 22m
American Airlines
Deal found 2/20$605

Find flight deals from Knoxville to Cartagena

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Cartagena (CTG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2026.

Round-trip from

$547
(Kiwi.com)
From Knoxville McGhee Tyson to Cartagena Rafael Nunez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Cartagena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Knoxville to Cartagena that are best for you.

Fly from

Knoxville

Fly to

Cartagena

Route

Depart

Return

Price

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Sat 4/4

5:30 am-12:31 pm

1 stop8h 01m

Cartagena Rafael Nunez

Sat 4/11

1:25 pm-10:26 am

2 stops20h 01m

$601

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Sun 6/14

6:47 pm-12:25 pm

2 stops18h 38m

Cartagena Rafael Nunez

Mon 6/22

3:13 pm-10:52 am

2 stops18h 39m

$782

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Sun 6/14

6:00 am-2:13 pm

1 stop9h 13m

Cartagena Rafael Nunez

Sun 6/21

3:13 pm-10:36 am

2 stops18h 23m

$798

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Sat 6/13

8:47 pm-12:05 pm

1 stop16h 18m

Cartagena Rafael Nunez

Mon 6/22

1:21 pm-4:12 pm

1 stop25h 51m

$811

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Fri 6/12

1:36 pm-12:05 pm

1 stop23h 29m

Cartagena Rafael Nunez

Mon 6/22

1:21 pm-4:12 pm

1 stop25h 51m

$817

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Fri 6/12

10:00 am-11:01 pm

2 stops14h 01m

Cartagena Rafael Nunez

Sat 6/20

6:20 am-11:12 pm

2 stops15h 52m

$1,401

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

Fri 6/12

12:10 pm-11:01 pm

2 stops11h 51m

Cartagena Rafael Nunez

Sun 6/21

6:20 am-11:12 pm

2 stops15h 52m

$1,767

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Best time to book a flight from Knoxville to Cartagena

Have a flexible travel schedule? Discover the best time to fly to Cartagena from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cartagena

Get insights into the airlines that provide service to Cartagena. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cartagena. Reviews last updated February 20, 2026.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Cartagena to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,321 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,321 reviews
American Airlines
7.2
Good
11,321 reviews

Comfort

7.2

Entertainment

6.9

Food

6.4

Overall

7.2

Crew

8.0

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Cartagena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Cartagena?

    Airlines like American Airlines fly from Knoxville to Cartagena in about 8h 01m. The time it takes to get you to your destination can typically vary by up to . There are 1830 mi between Knoxville and Cartagena.

  • What is the cheapest airline to fly from Knoxville to Cartagena round-trip?

    Currently priced at $537, American Airlines will fly you from Knoxville to Cartagena and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Knoxville to Cartagena that include hotel bookings?

    Yes. In addition to deals on Knoxville to Cartagena flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Cartagena?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cartagena.

  • Can I find deals for business class flights from Knoxville to Cartagena?

    Yes. Cheapflights offers flight deals from Knoxville to Cartagena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Cartagena?

Book flights to Cartagena if you plan to visit one of these locations
Boca Grande

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Top airline flying from Knoxville to Cartagena

Discover the top airline that operate flights from Knoxville to Cartagena. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$537Average$742FlexibilityNo cancel feeOn-time71%

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