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Cartagena

$488+ Cheap flights from Knoxville (TYS) to Cartagena (CTG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CTG
ene. 15 — ene. 221
jue. 1/15
jue. 1/22
1 adult, Economy
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Cheap flight deals from Knoxville to Cartagena

Cheapest flights from Knoxville to Cartagena
Explore the most affordable flight options available from Knoxville to Cartagena. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/299:20 pmTYS - CTG
1 stop15h 50mMultiple Airlines
jue. 1/12:15 pmCTG - TYS
1 stop18h 18mMultiple Airlines
Deal found 12/15$818
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/295:00 amTYS - CTG
2 stops16h 30mAmerican Airlines
jue. 1/12:30 pmCTG - TYS
1 stop10h 08mAmerican Airlines
Deal found 12/15$823

Find flight deals from Knoxville to Cartagena

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Cartagena (CTG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 16, 2025.

Round-trip from

$488
(Avianca)
From Knoxville McGhee Tyson to Cartagena Rafael Nunez
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Cartagena that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
Use the filters below to find and compare flights from Knoxville to Cartagena that are best for you.

Fly from

Knoxville

Fly to

Cartagena

Route

Depart

Return

Price

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

jue. 1/22

9:30 am-11:40 pm

2 stops14h 10m

Cartagena Rafael Nunez

mar. 1/27

4:20 pm-10:57 am

2 stops18h 37m

$488

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

mié. 4/1

5:30 am-1:15 pm

1 stop8h 45m

Cartagena Rafael Nunez

mié. 4/8

2:30 pm-11:51 pm

1 stop8h 21m

$529

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

mié. 4/8

7:15 am-12:10 pm

1 stop5h 55m

Cartagena Rafael Nunez

mié. 4/15

1:55 pm-11:14 pm

1 stop8h 19m

$529

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

mié. 4/8

7:00 am-10:58 pm

3 stops16h 58m

Cartagena Rafael Nunez

mié. 4/15

6:21 am-7:34 pm

2 stops12h 13m

$531

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

mié. 4/1

7:00 am-10:58 pm

2 stops16h 58m

Cartagena Rafael Nunez

mié. 4/8

6:21 am-11:19 pm

2 stops15h 58m

$531

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

mié. 4/8

5:30 am-1:15 pm

1 stop8h 45m

Cartagena Rafael Nunez

mié. 4/15

11:50 am-11:46 pm

2 stops10h 56m

$532

KnoxvilleCartagena

TYS - CTG

TYSCTG

Knoxville McGhee Tyson

sáb. 4/4

7:00 am-10:58 pm

2 stops16h 58m

Cartagena Rafael Nunez

mié. 4/8

6:21 am-11:19 pm

2 stops15h 58m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from Knoxville to Cartagena

Have a flexible travel schedule? Discover the best time to fly to Cartagena from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cartagena

Get insights into the airlines that provide service to Cartagena. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cartagena. Reviews last updated diciembre 16, 2025.
Peruse reviews from past customers who have flown with American Airlines from Knoxville to Cartagena to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,049 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Food

6.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,049 reviews
American Airlines
7.2
Good
11,049 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Food

6.5

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Cartagena. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Cartagena?

    Airlines like Avianca, Delta, and American Airlines fly from Knoxville to Cartagena in about 5h 55m. The time it takes to get you to your destination can typically vary by up to 8h 15m. There are 1830 mi between Knoxville and Cartagena. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Knoxville to Cartagena round-trip?

    Currently priced at $537, American Airlines will fly you from Knoxville to Cartagena and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Knoxville to Cartagena that include hotel bookings?

    Yes. In addition to deals on Knoxville to Cartagena flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Cartagena?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Cartagena.

  • Can I find deals for business class flights from Knoxville to Cartagena?

    Yes. Cheapflights offers flight deals from Knoxville to Cartagena by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Cartagena?

Book flights to Cartagena if you plan to visit one of these locations
Boca Grande

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Top airline flying from Knoxville to Cartagena

Discover the top airline that operate flights from Knoxville to Cartagena. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$537Average$791FlexibilityNo cancel feeOn-time71%

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