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Panama City

$256+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
May 24 — May 311
Sun 5/24
Sun 5/31
1 adult, Economy
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Cheap flight deals from Detroit to Panama City

Cheapest flights from Detroit to Panama City
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2026.

This Mytrip deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Sun 5/314:25 am
PTY
-
DTW
3 stops26h 27m
Multiple Airlines
Deal found 4/20$499
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 am
DTW
-
PTY
3 stops19h 05m
Multiple Airlines
Wed 5/204:25 am
PTY
-
DTW
2 stops18h 28m
Multiple Airlines
Deal found 4/22$526
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Sun 5/174:25 am
PTY
-
DTW
3 stops26h 27m
Multiple Airlines
Deal found 4/21$540
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
DTW
-
PTY
2 stops28h 15m
Multiple Airlines
Tue 5/265:55 pm
PTY
-
DTW
2 stops28h 58m
Multiple Airlines
Deal found 4/21$576
This Trip.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:50 am
DTW
-
PTY
3 stops20h 05m
Multiple Airlines
Tue 6/94:25 am
PTY
-
DTW
3 stops30h 10m
Multiple Airlines
Deal found 4/24$590

Find flight deals from Detroit to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$499
(Mytrip)

One-way from

$256
(Kiwi.com)

Popular in

April

Cheapest in

October

Average price

$1,139
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Panama City Tocumen Intl flights.
Search Deals
From Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($98 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

10:55 am-6:37 pm

1 stop8h 42m

Panama City Tocumen Intl

Wed 9/30

9:45 am-8:37 pm

1 stop9h 52m

$733
Quickest round-trip

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/16

6:30 am-12:56 pm

1 stop7h 26m

Panama City Tocumen Intl

Wed 9/30

2:21 pm-11:40 pm

1 stop8h 19m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 9/9

5:20 am-1:13 pm

1 stop8h 53m

Panama City Tocumen Intl

Wed 9/23

2:21 pm-11:40 pm

1 stop8h 19m

$733

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 9/15

5:50 am-6:37 pm

2 stops13h 47m

Panama City Tocumen Intl

Tue 9/29

10:00 am-10:30 pm

1 stop11h 30m

$737

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 7/23

7:00 am-4:04 am

1 stop22h 04m

Panama City Tocumen Intl

Fri 7/31

10:55 pm-9:26 am

1 stop9h 31m

$769

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 7/23

5:20 am-1:05 pm

1 stop8h 45m

Panama City Tocumen Intl

Fri 7/31

2:24 pm-11:54 pm

1 stop8h 30m

$783

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 10/17

5:45 am-6:37 pm

2 stops13h 52m

Panama City Tocumen Intl

Sat 11/7

10:00 am-7:38 pm

1 stop9h 38m

$790

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 6/16

6:15 am-6:37 pm

1 stop13h 22m

Panama City Tocumen Intl

Tue 6/30

9:45 am-8:13 pm

1 stop9h 28m

$792
Cheapest one-way

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 6/19

6:10 am-8:30 am

2 stops27h 20m

$256

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 6/18

2:02 pm-7:20 pm

2 stops30h 18m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 15 resultsSorted by cheapest first
1
2

Compare providers for flights from Detroit to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $704). Flying from Detroit Metropolitan Wayne County Airport to Panama City in April is currently the most expensive (average of $1,139). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 24, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andUnited Airlines from Detroit Metropolitan Wayne County Airport to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,451 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,451 reviews
Delta
7.9
Good
8,451 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,577 reviews
Delta
7.9
Good
8,451 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,643 reviews
Delta
7.9
Good
8,451 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,666 reviews
Delta
7.9
Good
8,451 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Panama City?

    A quick flight from Detroit Metropolitan Wayne County Airport to Panama City can take about 7h 26m. United Airlines provides one of the quickest options available for as low as $733. The distance from Detroit Metropolitan Wayne County Airport to Panama City is about 2302 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to Panama City round-trip?

    According to our current data, Copa Airlines ($611), American Airlines ($628), and United Airlines ($629) offers the cheapest pricing from Detroit Metropolitan Wayne County Airport to Panama City. These flights start at 26% lower than the current average price 3 months from now.

  • Can I find deals for flights from Detroit to Panama City that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama City.

  • Can I find deals for business class flights from Detroit to Panama City?

    Yes. Cheapflights offers flight deals from Detroit to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City (average of $704). Flying from Detroit Metropolitan Wayne County Airport to Panama City in April is currently the most expensive (average of $1,139). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Detroit to Panama City

Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$611Average$801FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$628Average$821FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$629Average$811FlexibilityNo cancel feeOn-time69%
DeltaCheapest$668Average$907FlexibilityNo cancel feeOn-timeN/A

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