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Wilkes-Barre

$254+ Cheap flights from Des Moines (DSM) to Wilkes-Barre, PA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ABE
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Wilkes-Barre

Cheapest flights from Des Moines to Wilkes-Barre
Explore the most affordable flight options available from Des Moines to Wilkes-Barre. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:40 amDSM - AVP
1 stop11h 39mAmerican Airlines
Mon 12/296:00 amAVP - DSM
1 stop7h 54mAmerican Airlines
Deal found 12/10$395
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/253:14 pmDSM - AVP
1 stop4h 31mUnited Airlines
Mon 12/297:45 pmAVP - DSM
2 stops23h 20mUnited Airlines
Deal found 12/10$486
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/224:03 pmDSM - AVP
1 stop15h 38mMultiple Airlines
Tue 12/238:32 pmAVP - DSM
1 stop24h 55mMultiple Airlines
Deal found 12/9$516
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:14 pmDSM - AVP
1 stop4h 31mUnited Airlines
Sun 12/287:45 pmAVP - DSM
2 stops26h 55mUnited Airlines
Deal found 12/9$580
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:47 amDSM - AVP
1 stop9h 32mAmerican Airlines
Sun 12/286:00 amAVP - DSM
1 stop9h 53mAmerican Airlines
Deal found 12/9$622
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:00 amDSM - AVP
1 stop7h 25mUnited Airlines
Tue 12/2310:31 amAVP - DSM
2 stops12h 09mUnited Airlines
Deal found 12/9$673

Find flight deals from Des Moines to Wilkes-Barre

Keep the following information in mind while searching for Des Moines to Wilkes-Barre flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$315
(United Airlines)

One-way from

$254
(American Airlines)
Provider with most accurate pricing for Des Moines-Wilkes-Barre Scranton flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Wilkes-Barre Scranton flights.
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From Des Moines to Wilkes-Barre
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One-way flight from Des Moines to Wilkes-Barre
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Wilkes-Barre that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Wilkes-Barre that are best for you.

Fly from

Des Moines

Fly to

Wilkes-Barre

Route

Depart

Return

Price

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Sat 1/24

3:35 pm-9:00 pm

1 stop4h 25m

Wilkes-Barre Scranton

Wed 1/28

10:00 am-2:33 pm

1 stop5h 33m

$315

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Thu 12/25

6:40 am-7:19 pm

1 stop11h 39m

Wilkes-Barre Scranton

Mon 12/29

6:00 am-12:54 pm

1 stop7h 54m

$395

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Fri 1/23

6:48 pm-9:00 pm

1 stop25h 12m

Wilkes-Barre Scranton

Tue 1/27

5:17 pm-9:50 pm

1 stop5h 33m

$416

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Fri 1/23

3:35 pm-9:00 pm

1 stop4h 25m

Wilkes-Barre Scranton

Fri 1/30

7:45 pm-9:50 pm

2 stops27h 05m

$428

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Thu 12/25

3:14 pm-8:45 pm

1 stop4h 31m

Wilkes-Barre Scranton

Mon 12/29

7:45 pm-6:05 pm

2 stops23h 20m

$486

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Sun 5/3

2:38 pm-9:33 pm

1 stop5h 55m

$254

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Wed 12/17

3:18 pm-9:10 pm

1 stop4h 52m

$305

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Thu 12/18

8:00 am-4:25 pm

1 stop7h 25m

$329

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Tue 12/16

3:17 pm-8:49 pm

1 stop4h 32m

$330

Des MoinesScranton

DSM - AVP

DSMAVP

Des Moines

Tue 12/16

10:00 am-8:41 am

3 stops45h 41m

$352

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 13 results
1
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Best time to book a flight from Des Moines to Wilkes-Barre

Have a flexible travel schedule? Discover the best time to fly to Wilkes-Barre from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Wilkes-Barre
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Wilkes-Barre

Get insights into the airlines that provide service to Wilkes-Barre. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Wilkes-Barre. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown American Airlines from Des Moines to Wilkes-Barre. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Entertainment

6.9

Food

6.5

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Entertainment

6.9

Food

6.5

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Wilkes-Barre. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Wilkes-Barre?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly out of when you book flights from Des Moines to Wilkes-Barre. 3 airlines have flights from Des Moines to Wilkes-Barre on a regular basis. Booking flights from Des Moines to Wilkes-Barre should not be difficult; the airport handles an average of 0 outbound flights to Wilkes-Barre per day.

  • How long is the flight from Des Moines to Wilkes-Barre?

    United Airlines can get you from Des Moines to Wilkes-Barre in just under 4h 25m. Your travel time can differ by up to . Des Moines and Wilkes-Barre are separated by a distance of 927 mi.

  • Can I find deals for flights from Des Moines to Wilkes-Barre that include hotel bookings?

    Yes. In addition to deals on Des Moines to Wilkes-Barre flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Wilkes-Barre?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Wilkes-Barre.

  • Can I find deals for business class flights from Des Moines to Wilkes-Barre?

    Yes. Cheapflights offers flight deals from Des Moines to Wilkes-Barre by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from Des Moines to Wilkes-Barre

Discover the top 3 airlines that operate flights from Des Moines to Wilkes-Barre. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$256Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$283Average$490FlexibilityNo cancel feeOn-time69%
DeltaCheapest$304Average$364FlexibilityNo cancel feeOn-timeN/A

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