$126+ Cheap flights from South Dakota to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Mar 6 — Mar 131
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Dakota to St. Louis
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Cheapest flights from South Dakota to St. LouisExplore the most affordable flight options available from South Dakota to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
Explore the most affordable flight options available from South Dakota to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:51 pm
FSD
- STL
1 stop5h 07m
United Airlines
Tue 6/25:29 pm
STL
- FSD
1 stop4h 09m
United Airlines
Deal found 2/1![United Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Sun 2/226:25 am
STL
- FSD
1 stop4h 21m
United Airlines
Deal found 2/3![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:29 pm
RAP
- STL
1 stop5h 54m
Delta
Mon 3/96:29 am
STL
- RAP
1 stop4h 51m
Delta
Deal found 2/1![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
FSD
- STL
1 stop7h 05m
American Airlines
Sat 3/288:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Sat 2/218:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/3![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:29 pm
RAP
- STL
1 stop5h 54m
Delta
Sat 2/216:10 am
STL
- RAP
1 stop4h 55m
Delta
Deal found 2/1![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:00 am
FSD
- STL
1 stop6h 24m
Delta
Sun 3/296:29 am
STL
- FSD
1 stop3h 52m
Delta
Deal found 2/2![Delta logo]()
$288
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/22:52 pm
RAP
- STL
1 stop4h 34m
United Airlines
Mon 3/95:15 am
STL
- RAP
1 stop4h 55m
United Airlines
Deal found 2/2![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/134:29 pm
RAP
- STL
1 stop5h 54m
Delta
Mon 2/165:29 pm
STL
- RAP
1 stop5h 58m
Delta
Deal found 2/2![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Sat 2/217:41 am
STL
- FSD
1 stop6h 59m
United Airlines
Deal found 2/4![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:15 pm
FSD
- STL
1 stop3h 59m
United Airlines
Wed 2/182:45 pm
STL
- FSD
1 stop5h 54m
United Airlines
Deal found 2/2![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:10 pm
RAP
- STL
1 stop6h 15m
Delta
Sat 2/1411:30 am
STL
- RAP
1 stop5h 14m
Delta
Deal found 2/2![Delta logo]()
$339
Best flights from South Dakota to St. LouisDiscover carefully curated flight deals from South Dakota to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
Discover carefully curated flight deals from South Dakota to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 4, 2026.
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:51 pm
FSD
- STL
1 stop5h 07m
United Airlines
Tue 6/25:29 pm
STL
- FSD
1 stop4h 09m
United Airlines
Deal found 2/1![United Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/181:26 pm
FSD
- STL
1 stop6h 03m
American Airlines
Sat 2/218:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:29 pm
RAP
- STL
1 stop5h 54m
Delta
Mon 3/96:29 am
STL
- RAP
1 stop4h 51m
Delta
Deal found 2/1![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Sun 2/226:25 am
STL
- FSD
1 stop4h 21m
United Airlines
Deal found 2/3![United Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/137:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Wed 5/205:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 2/4![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:29 pm
RAP
- STL
1 stop5h 54m
Delta
Sat 2/216:10 am
STL
- RAP
1 stop4h 55m
Delta
Deal found 2/1![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:45 pm
FSD
- STL
1 stop4h 14m
United Airlines
Mon 2/234:49 pm
STL
- FSD
1 stop5h 08m
United Airlines
Deal found 2/4![United Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
FSD
- STL
1 stop7h 05m
American Airlines
Sat 3/288:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/11:20 pm
FSD
- STL
1 stop3h 25m
Delta
Mon 8/35:30 pm
STL
- FSD
1 stop5h 16m
Delta
Deal found 2/2![Delta logo]()
$288
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Sat 2/218:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/3![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:00 am
FSD
- STL
1 stop6h 24m
Delta
Sun 3/296:29 am
STL
- FSD
1 stop3h 52m
Delta
Deal found 2/2![Delta logo]()
$288
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:45 pm
FSD
- STL
1 stop4h 14m
United Airlines
Sat 2/217:41 am
STL
- FSD
1 stop6h 59m
United Airlines
Deal found 2/1![United Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:15 pm
FSD
- STL
1 stop5h 50m
United Airlines
Wed 2/186:00 pm
STL
- FSD
1 stop5h 44m
United Airlines
Deal found 1/31![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
RAP
- STL
1 stop4h 32m
Delta
Sat 5/165:47 pm
STL
- RAP
1 stop5h 37m
Delta
Deal found 2/2![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/2510:55 am
RAP
- STL
1 stop5h 03m
United Airlines
Sat 2/284:30 pm
STL
- RAP
1 stop5h 14m
United Airlines
Deal found 2/3![United Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/22:52 pm
RAP
- STL
1 stop4h 34m
United Airlines
Sat 3/75:15 am
STL
- RAP
1 stop6h 05m
United Airlines
Deal found 2/2![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:54 am
RAP
- STL
2 stops8h 49m
Delta
Sat 3/76:10 am
STL
- RAP
1 stop4h 55m
Delta
Deal found 2/2![Delta logo]()
$412
Last-minute flights from South Dakota to St. LouisDiscover last-minute flight deals from South Dakota to St. Louis. Data last updated February 4, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to St. Louis. Data last updated February 4, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/712:35 pm
RAP
- STL
1 stop7h 23m
United Airlines
Tue 2/104:15 pm
STL
- RAP
1 stop5h 17m
United Airlines
Deal found 2/3![United Airlines logo]()
$354
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:10 pm
RAP
- STL
1 stop6h 15m
Delta
Sat 2/1411:30 am
STL
- RAP
1 stop5h 14m
Delta
Deal found 2/2![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/134:29 pm
RAP
- STL
1 stop5h 54m
Delta
Mon 2/165:29 pm
STL
- RAP
1 stop5h 58m
Delta
Deal found 2/2![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/143:15 pm
FSD
- STL
1 stop5h 50m
United Airlines
Wed 2/186:25 am
STL
- FSD
1 stop4h 21m
United Airlines
Deal found 2/3![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:29 pm
RAP
- STL
1 stop5h 54m
Delta
Sat 2/216:10 am
STL
- RAP
1 stop4h 55m
Delta
Deal found 2/1![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Sun 2/226:25 am
STL
- FSD
1 stop4h 21m
United Airlines
Deal found 2/3![United Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Sat 2/218:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/3![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Sat 2/217:41 am
STL
- FSD
1 stop6h 59m
United Airlines
Deal found 2/4![United Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:29 pm
RAP
- STL
1 stop5h 54m
Delta
Mon 3/96:29 am
STL
- RAP
1 stop4h 51m
Delta
Deal found 2/1![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/22:52 pm
RAP
- STL
1 stop4h 34m
United Airlines
Mon 3/95:15 am
STL
- RAP
1 stop4h 55m
United Airlines
Deal found 2/2![United Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/252:06 pm
FSD
- STL
1 stop7h 05m
American Airlines
Sat 3/288:00 am
STL
- FSD
1 stop5h 33m
American Airlines
Deal found 2/2![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:00 am
FSD
- STL
1 stop6h 24m
Delta
Sun 3/296:29 am
STL
- FSD
1 stop3h 52m
Delta
Deal found 2/2![Delta logo]()
$288
One-way flights from South Dakota to St. LouisSearch for one-way flight options from South Dakota to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
Search for one-way flight options from South Dakota to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- STL
1 stop22h 53m
Frontier
Deal found 1/31![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:35 pm
FSD
- STL
2 stops32h 44m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:56 am
FSD
- STL
1 stop5h 53m
Delta
Deal found 2/2![Delta logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:51 pm
FSD
- STL
3 stops36h 00m
Multiple Airlines
Deal found 1/31![Multiple Airlines logo]()
$325
Find flight deals from South Dakota to St. Louis
Keep the following information in mind while searching for South Dakota to St. Louis flight deals. Data was last updated February 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (United Airlines) |
One-way from | $126 (Kiwi.com) |
Popular in | July |
Cheapest in | August |
Average price | $298 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from South Dakota to St. Louis that are best for you.
Fly from
South Dakota
Fly to
St. Louis
Route
Depart
Return
Price
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 5/27
6:51 pm-11:58 pm
1 stop5h 07m
Lambert-St Louis
Tue 6/2
5:29 pm-9:38 pm
1 stop4h 09m
$249
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 2/18
1:26 pm-7:29 pm
1 stop6h 03m
Lambert-St Louis
Sat 2/21
8:00 am-1:33 pm
1 stop5h 33m
$259
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 2/18
9:00 am-4:58 pm
1 stop7h 58m
Lambert-St Louis
Sun 2/22
6:25 am-10:46 am
1 stop4h 21m
$259
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 2/19
6:45 pm-10:59 pm
1 stop4h 14m
Lambert-St Louis
Mon 2/23
4:49 pm-9:57 pm
1 stop5h 08m
$259
Rapid CitySt. Louis
RAP - STL
RAPSTL
Rapid City
Mon 3/2
4:29 pm-11:23 pm
1 stop5h 54m
Lambert-St Louis
Mon 3/9
6:29 am-10:20 am
1 stop4h 51m
$269
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 5/13
7:39 pm-11:56 pm
1 stop4h 17m
Lambert-St Louis
Wed 5/20
5:20 am-12:56 pm
1 stop7h 36m
$274
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 3/25
2:06 pm-9:11 pm
1 stop7h 05m
Lambert-St Louis
Sat 3/28
8:00 am-1:33 pm
1 stop5h 33m
$274
Rapid CitySt. Louis
RAP - STL
RAPSTL
Rapid City
Tue 2/17
4:29 pm-11:23 pm
1 stop5h 54m
Lambert-St Louis
Sat 2/21
6:10 am-10:05 am
1 stop4h 55m
$279
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 2/19
7:42 pm-11:48 pm
1 stop4h 06m
Lambert-St Louis
Sat 2/21
8:00 am-1:33 pm
1 stop5h 33m
$279
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 8/1
1:20 pm-4:45 pm
1 stop3h 25m
Lambert-St Louis
Mon 8/3
5:30 pm-10:46 pm
1 stop5h 16m
$288
Showing 1-10 of 21 results
Best time to book a flight from South Dakota to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from South Dakota with our price prediction graph.
FSD-STL
RAP-STL
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Everything you need to know about your flight from South Dakota to St. Louis
USSD-STL
FSD-STL
RAP-STL
What is the cheapest month to book a flight from South Dakota to St. Louis?
Currently, May is the cheapest month in which you can book a flight from South Dakota to St. Louis (average of $188). Flying from South Dakota to St. Louis in November is currently the most expensive (average of $378). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Dakota to St. Louis?
Related info for your journey
Find useful and relevant information for your journey from South Dakota to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus
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South Dakota and St. Louis flights
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South Dakota to St. Louis flights
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Top 3 airlines flying from South Dakota to St. Louis
Discover the top 3 airlines that operate flights from South Dakota to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$174 | Average$301 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$289 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$264 | Average$363 | FlexibilityNo cancel fee | On-time69% |