$145+ Cheap flights from South Dakota to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Oct 2 — Oct 91
Round-trip
1 adult, Economy
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Find cheap flights from South Dakota to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Dakota to St. Louis
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Best
Last-minute
One-way
Cheapest flights from South Dakota to St. LouisExplore the most affordable flight options available from South Dakota to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
Explore the most affordable flight options available from South Dakota to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 2, 2026.
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:50 pm -
1 stop4h 50m
Sat 9/129:00 am -
1 stop7h 33m
Deal found 9/1![United Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:56 pm -
1 stop5h 08m
Tue 10/611:31 am -
2 stops9h 42m
Deal found 9/1![American Airlines logo]()
$286
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop6h 15m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/29![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm -
1 stop6h 11m
Sun 9/135:43 am -
1 stop6h 33m
Deal found 8/30![American Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:07 pm -
1 stop5h 20m
Sun 9/275:43 am -
1 stop5h 04m
Deal found 9/2![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:07 pm -
1 stop5h 20m
Sun 9/205:43 am -
1 stop5h 04m
Deal found 8/31![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop4h 38m
Sat 10/314:39 pm -
1 stop5h 04m
Deal found 9/1![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am -
1 stop4h 40m
Mon 9/144:40 pm -
1 stop6h 53m
Deal found 8/30![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:05 am -
2 stops13h 16m
Sun 9/276:00 am -
1 stop5h 15m
Deal found 8/31![United Airlines logo]()
$566
Best flights from South Dakota to St. LouisDiscover carefully curated flight deals from South Dakota to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
Discover carefully curated flight deals from South Dakota to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 2, 2026.
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:41 pm -
1 stop5h 46m
Sat 10/311:01 am -
2 stops9h 44m
Deal found 8/28![American Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:50 am -
1 stop4h 23m
Sun 10/45:36 pm -
1 stop5h 35m
Deal found 8/28![United Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:35 am -
1 stop6h 59m
Sun 9/206:55 pm -
1 stop4h 49m
Deal found 9/1![United Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:07 pm -
1 stop5h 20m
Sun 9/205:43 am -
1 stop5h 04m
Deal found 8/31![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:20 pm -
1 stop7h 39m
Sat 10/311:40 pm -
1 stop6h 24m
Deal found 8/30![United Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:56 pm -
2 stops11h 31m
Sun 10/45:43 am -
1 stop6h 33m
Deal found 8/28![American Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop4h 38m
Sat 10/314:39 pm -
1 stop5h 04m
Deal found 9/1![United Airlines logo]()
$399
Last-minute flights from South Dakota to St. LouisDiscover last-minute flight deals from South Dakota to St. Louis. Data last updated September 2, 2026 and is based on user searches.
Discover last-minute flight deals from South Dakota to St. Louis. Data last updated September 2, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:56 pm -
1 stop6h 11m
Sun 9/135:43 am -
1 stop6h 33m
Deal found 8/30![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:50 pm -
1 stop4h 50m
Sat 9/129:00 am -
1 stop7h 33m
Deal found 9/1![United Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:56 pm -
1 stop5h 08m
Tue 10/611:31 am -
2 stops9h 42m
Deal found 9/1![American Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 am -
1 stop4h 40m
Mon 9/144:40 pm -
1 stop6h 53m
Deal found 8/30![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:07 pm -
1 stop5h 20m
Sun 9/205:43 am -
1 stop5h 04m
Deal found 8/31![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop6h 15m
Mon 9/215:18 pm -
1 stop7h 11m
Deal found 8/29![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:07 pm -
1 stop5h 20m
Sun 9/275:43 am -
1 stop5h 04m
Deal found 9/2![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/247:05 am -
2 stops13h 16m
Sun 9/276:00 am -
1 stop5h 15m
Deal found 8/31![United Airlines logo]()
$566
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:56 pm -
1 stop5h 08m
Tue 10/65:00 am -
1 stop6h 34m
Deal found 9/1![American Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop4h 38m
Sat 10/314:39 pm -
1 stop5h 04m
Deal found 9/1![United Airlines logo]()
$399
One-way flights from South Dakota to St. LouisSearch for one-way flight options from South Dakota to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
Search for one-way flight options from South Dakota to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/219:55 am -
3 stops51h 15m
Deal found 8/31![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:52 pm -
2 stops40h 18m
Deal found 8/31![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:02 pm -
3 stops45h 15m
Deal found 9/2![Multiple Airlines logo]()
$260
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:48 pm -
1 stop6h 09m
Deal found 8/31![American Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:55 am -
1 stop6h 36m
Deal found 8/31![Delta logo]()
$274
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:16 am -
2 stops11h 13m
Deal found 8/31![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:12 am -
1 stop4h 26m
Deal found 8/29![United Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:42 am -
2 stops13h 17m
Deal found 9/1![United Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:48 pm -
3 stops45h 29m
Deal found 9/2![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:56 pm -
3 stops38h 39m
Deal found 9/1![Multiple Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:18 pm -
3 stops43h 38m
Deal found 8/31![Multiple Airlines logo]()
$447
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:04 pm -
3 stops25h 39m
Deal found 8/31![United Airlines logo]()
$449
Find flight deals from South Dakota to St. Louis
Keep the following information in mind while searching for South Dakota to St. Louis flight deals. Data was last updated September 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $281 (American Airlines) |
One-way from | $145 (Kiwi.com) |
Popular in | May |
Cheapest in | December |
Average price | $388 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Dakota to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
Use the filters below to find and compare flights from South Dakota to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/30
6:41 pm-12:27 am
1 stop5h 46m
Lambert-St Louis
Sat 10/3
11:01 am-8:45 pm
2 stops9h 44m
$286
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/30
7:50 am-12:13 pm
1 stop4h 23m
Lambert-St Louis
Sun 10/4
5:36 pm-11:11 pm
1 stop5h 35m
$290
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Tue 9/29
12:56 pm-6:04 pm
1 stop5h 08m
Lambert-St Louis
Tue 10/6
5:00 am-11:34 am
1 stop6h 34m
$290
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/16
9:35 am-4:34 pm
1 stop6h 59m
Lambert-St Louis
Sun 9/20
6:55 pm-11:44 pm
1 stop4h 49m
$329
Rapid CitySt. Louis
RAP Rapid City - STL Lambert-St Louis
RAPSTL
Rapid City
Wed 9/16
6:07 pm-12:27 am
1 stop5h 20m
Lambert-St Louis
Sun 9/20
5:43 am-9:47 am
1 stop5h 04m
$349
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 10/28
1:20 pm-8:59 pm
1 stop7h 39m
Lambert-St Louis
Sat 10/31
1:40 pm-8:04 pm
1 stop6h 24m
$351
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Wed 9/30
12:56 pm-12:27 am
2 stops11h 31m
Lambert-St Louis
Sun 10/4
5:43 am-12:16 pm
1 stop6h 33m
$380
Quickest round-trip
Rapid CitySt. Louis
RAP Rapid City - STL Lambert-St Louis
RAPSTL
Rapid City
Wed 10/28
7:00 am-12:38 pm
1 stop4h 38m
Lambert-St Louis
Sat 10/31
4:39 pm-8:43 pm
1 stop5h 04m
$399
Cheapest one-way
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Mon 9/21
9:55 am-1:10 pm
3 stops51h 15m
$145
Sioux FallsSt. Louis
FSD Sioux Falls Joe Foss Field - STL Lambert-St Louis
FSDSTL
Sioux Falls Joe Foss Field
Mon 9/21
8:52 pm-1:10 pm
2 stops40h 18m
$185
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from South Dakota to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from South Dakota with our price prediction graph.
FSD-STL
RAP-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Dakota to St. Louis
USSD-STL
FSD-STL
RAP-STL
What is the cheapest month to book a flight from South Dakota to St. Louis?
Currently, December is the cheapest month in which you can book a flight from South Dakota to St. Louis (average of $303). Flying from South Dakota to St. Louis in June is currently the most expensive (average of $617). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Dakota to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
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South Dakota and St. Louis flights
Browse other South Dakota and St. Louis flight options. Last updated on September 2, 2026.
Popular flight searches
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 2, 2026.
South Dakota to St. Louis flights
Consider these flights traveling from South Dakota to St. Louis.
Top 3 airlines flying from South Dakota to St. Louis
Discover the top 3 airlines that operate flights from South Dakota to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$192 | Average$373 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$208 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$377 | FlexibilityNo cancel fee | On-time71% |